60 research outputs found

    Comment Sanna Marin est-elle representée dans deux articles de journaux franco-phones?

    No full text
    Tämän tutkielman tarkoituksena on vertailla kahta ranskankielistä aikakauslehden artikkelia (Le Journal des Femmes ja L’Illustré). Nämä lehdet julkaisivat artikkelin Sanna Marinista sen jälkeen, kun hänet valittiin Suomen pääministeriksi vuonna 2019. Media on tiedon ja viestinnän väline, mutta se vaikuttaa myös ta paamme nähdä asiat. Tutkimuksen pääkysymys on se, millaisena henkilönä Sanna Marin esitetään näissä aikakauslehtiartikkeleissa. Tämä tutkimuksen teoreettinen viitekehys sijoittuu diskurssianalyysin kentälle. Kyseessä on laadullinen tutkimus. Tutkielma keskittyy representaation käsitteeseen selvittääkseen kuvaa, jonka nämä artikkelit antavat nuoresta pääministeristä. Lisäksi tutkielma analysoi käytettyä kieltä. Suoritetun analyysin perusteella on päädytty siihen, että Sanna Marin on esitetty näissä sanomalehdissä lähes identtisesti: Marin nuorena johtajana, Marin päättäväisenä naisena, Marin ympäristönsuojelijana, Marin tavallisena politiikkona. Näin ollen neljä representaatiota on esitett

    Megacystis Microcolon Intestinal Hypoperistalsis Syndrome

    No full text

    Congenital anomalies of kidney and urinary tract in siblings: An uncommon condition

    No full text
    Congenital anomalies of kidney and urinary tract (CAKUT) are important causes of chronic kidney disease (CKD) in childhood. Most do not have a definite identifiable genetic defect and occur in isolation. Rarely, familial occurrence of CAKUT has been reported. The burden of CKD to a family in a developing country is enormous, and if more than one child is afflicted with the condition, the situation is almost catastrophic. We present here two families with siblings having upper and lower urinary tract obstruction

    Adrenocortical suppression in children with nephrotic syndrome treated with low-dose alternate day corticosteroids

    No full text
    Corticosteroids form the mainstay of therapy for all forms of nephrotic syndrome. The long-term use of this medication is associated with serious side effects including adrenocortical suppression. The primary objective of this study was to identify adrenocortical suppression (assessed by single morning serum cortisol levels) in children with nephrotic syndrome on treatment with low-dose alternate day steroids. This cross-sectional study was conducted in the Department of Pediatrics in a tertiary care hospital from January 2014 to January 2015. Seventy children (1–18 years) with nephrotic syndrome (steroid sensitive and resistant) who were in remission and on low-dose alternate day steroids for at least 8 weeks or had received steroids of 2 mg/kg/d for at least 2 weeks in the last 1 year (infrequent relapsers) were enrolled. Relevant history was taken, clinical examination was done and blood samples were drawn for serum cortisol, lipid profile, kidney function tests, fasting blood sugar, glycated hemoglobin (HbA1c), and serum albumin. Forty percent (28/70) children had adrenocortical suppression as assessed by low morning serum cortisol levels. The mean serum cortisol levels were 188 nmol/L and were significantly lower in frequently relapsing individuals (85.9 nmol/L) as compared to other types of nephrotic syndrome (P = 0.05). The prevalence of adrenocortical suppression was higher in steroid-resistant patients (57%) as compared to 28% in frequently relapsing and 11% in steroid-dependent patients. Fifty-seven percent of patients with adrenocortical suppression had short stature while 50% had obesity. All individuals had normal serum HbA1clevels. The cumulative steroid doses and total duration of corticosteroid therapy were significantly higher in patients with adrenocortical suppression. Children with nephrotic syndrome treated with low-dose alternate day steroids have a high prevalence of adrenocortical suppression on screening with single morning cortisol sample. Those with frequently relapsing or steroid-resistant diseases are at a higher risk of suppression

    Comparison of hemodynamic response of small dose ketamine versus midazolam as co- induction agent to propofol: a randomized double blind interventional study

    No full text
    The Anaesthesiology Department at Sawai Man Singh Medical College carried out this study. For this, 60 ASA grade I and II patients undergoing planned general surgery were randomly assigned into two groups of 30 each, with Group KP (n=30) receiving injections of ketamine at 0.3 mg/kg and Group MP receiving injections of midozolam at 0.03 mg/kg and Propofol I.V. The main goal of the study was to find the best induction by analysing changes in hemodynamic indicators from baseline to various time points after induction. On the basis of the necessary induction dose and hemodynamic characteristics, the groups were contrasted. The strategy used was to present the categorical data as percentages and compare them between groups using the Chi square test. The mean and standard deviation of the quantitative data were displayed, and students' t-tests were used to compare them. According to the study described above, group MP saw a greater fluctuation in heart rate than did group KP, whose heart rate remained more constant during the anaesthetic time. Group MP's blood pressure dropped more quickly after induction compared to group KP. The ketamine group's blood pressure remained the most stable out of all the groups. Apnea, pain upon injection, and uncontrollable movements were absent in the KP group. Of all the groups, the ketamine-propofol group required the least induction dose. As a result, we came to the conclusion that pretreatment with ketamine at a dose of 0.3 mg/kg results in better hemodynamic stability and requires less propofol for induction than midazolam does. The ketamine-propofol group is therefore the best of the two groups, making it the optimum induction agen

    Focal nodular hyperplasia with steroid-resistant nephrotic syndrome: A paraneoplastic condition or coincidental findings?

    No full text
    Background: Paraneoplastic glomerulonephritis (GN) are defined as glomerular lesions not directly related to tumor burden, invasion, or metastasis but induced by products of tumor cells. They are usually associated with solid tumors of gastrointestinal tract and hematological malignancies. Nephrotic syndrome is a rare manifestation of paraneoplastic syndromes, especially in children and biopsy findings are usually those of minimal change disease (MCD) or membranous nephropathy. We describe a case of steroid-resistant nephrotic syndrome with focal nodular hyperplasia (FNH) of liver. To the best of our knowledge, this has not been reported previously. Clinical Description: A 9-year-old boy presented with features of nephrotic syndrome and had a significant hepatomegaly. Based on radiological features and histopathological confirmation, the child was diagnosed to have a hepatic tumor consistent with a diagnosis of FNH, and the renal biopsy was suggestive of MCD. Management: As FNH did not require a surgical intervention, the nephrotic syndrome was managed with prednisolone initially, but the patient failed to achieve remission and was subsequently started on oral tacrolimus with enalapril and low-dose alternate day prednisolone. Remission of proteinuria was achieved within 2 months, and the child has been in follow-up for the past 18 months and the liver mass has been stable. Conclusion: This report suggests a possible paraneoplastic GN (steroid-resistant nephrotic syndrome) with FNH of liver that responded to immunosuppression

    Mantoux test revisited: Variability in reading tuberculin test in pediatric population

    No full text

    Nephrotic Syndrome with Central Retinal Artery Occlusion: A Unique Presentation

    No full text
    Childhood nephrotic syndrome is associated with significant morbidity because of recurrent relapses, infections, and episodes of thromboembolism. Thromboembolism in nephrotic syndrome may involve any major blood vessel. Timely recognition of symptoms and early initiation of anticoagulation therapy are important to avoid end-organ damage. We present here a case of a child with steroid-resistant nephrotic syndrome (SRNS) with bilateral central retinal artery occlusion (CRAO), whose vision improved with anticoagulation therapy
    • …
    corecore