5 research outputs found
Platelet-Activating Factor Receptor Plays a Role in Lung Injury and Death Caused by Influenza A in Mice
- Author
- A Bedirli
- Alexandre V. Machado
- Ana Paula C. Salgado
- B Opitz
- BJ Zheng
- BR Ruf
- Caio T. Fagundes
- CR Crowe
- Cristiana C. Garcia
- D Bruder
- DG Souza
- DG Souza
- DL Barnard
- DS Fedson
- FJ Culley
- FY Aoki
- G Montrucchio
- Geovanni D. Cassali
- GK Marathe
- H Fujisawa
- H Shindou
- HC Santiago
- I Julkunen
- IC Allen
- J Gabrijelcic
- J McGill
- JA McCullers
- JA McCullers
- JC Horvat
- JE Kohlmeier
- JP Wang
- KF van der Sluijs
- KL Hartshorn
- KL Lin
- LA McNamee
- LA Perrone
- Lirlândia P. Sousa
- Luciana P. Tavares
- M Chignard
- M Kiso
- M Michaelis
- M Seki
- Mauro M. Teixeira
- MJ Tuvim
- ML Colamussi
- MR White
- N Schmitz
- NJ White
- NM Bouvier
- O Mandelboim
- PG Thomas
- R Le Goffic
- Rafael B. Polidoro
- RC Russo
- RE Young
- Remo C. Russo
- RG Landgraf
- Rodrigo Guabiraba
- Ron A. M. Fouchier
- S Ishii
- S Nourshargh
- S Sakai
- S Uhlig
- SM Prescott
- TM Tumpey
- TR Maines
- VA Dolgachev
- XJ Chen
- Y Hashimoto
- Y Imai
- Y Jin
- Y Mandi
- Y Watanabe
- YM Lee
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Influenza A virus causes annual epidemics which affect millions of people
worldwide. A recent Influenza pandemic brought new awareness over the health
impact of the disease. It is thought that a severe inflammatory response against
the virus contributes to disease severity and death. Therefore, modulating the
effects of inflammatory mediators may represent a new therapy against Influenza
infection. Platelet activating factor (PAF) receptor (PAFR) deficient mice were
used to evaluate the role of the gene in a model of experimental infection with
Influenza A/WSN/33 H1N1 or a reassortant Influenza A H3N1 subtype. The following
parameters were evaluated: lethality, cell recruitment to the airways, lung
pathology, viral titers and cytokine levels in lungs. The PAFR antagonist
PCA4248 was also used after the onset of flu symptoms. Absence or antagonism of
PAFR caused significant protection against flu-associated lethality and lung
injury. Protection was correlated with decreased neutrophil recruitment, lung
edema, vascular permeability and injury. There was no increase of viral load and
greater recruitment of NK1.1+ cells. Antibody responses were
similar in WT and PAFR-deficient mice and animals were protected from
re-infection. Influenza infection induces the enzyme that synthesizes PAF,
lyso-PAF acetyltransferase, an effect linked to activation of TLR7/8. Therefore,
it is suggested that PAFR is a disease-associated gene and plays an important
role in driving neutrophil influx and lung damage after infection of mice with
two subtypes of Influenza A. Further studies should investigate whether
targeting PAFR may be useful to reduce lung pathology associated with Influenza
A virus infection in humans
Measurement of the inclusive cross-section for the production of jets in association with a Z boson in proton-proton collisions at 8 TeV using the ATLAS detector
- Author
- Aad G
- Abbott B
- Abbott DC
- Abdinov O
- Abeling K
- Abhayasinghe DK
- Abidi SH
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- Abraham NL
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- Acharya BS
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- Zaripovas DR
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- Zenin O
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- Zhang M
- Zhang R
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Fachmedien Wiesbaden GmbH'
- Publication date
- 01/10/2019
- Field of study
The inclusive cross-section for jet production in association with a Z boson decaying into an electron–positron pair is measured as a function of the transverse momentum and the absolute rapidity of jets using 19.9 fb −1 of s√=8 TeV proton–proton collision data collected with the ATLAS detector at the Large Hadron Collider. The measured Z + jets cross-section is unfolded to the particle level. The cross-section is compared with state-of-the-art Standard Model calculations, including the next-to-leading-order and next-to-next-to-leading-order perturbative QCD calculations, corrected for non-perturbative and QED radiation effects. The results of the measurements cover final-state jets with transverse momenta up to 1 TeV, and show good agreement with fixed-order calculations
Persistent Alterations in Mesolimbic Gene Expression with Abstinence from Cocaine Self-Administration
- Author
- A Bisaga
- A Kumar
- AC Boudreau
- AM Graybiel
- AN Samaha
- AR Childress
- BC Wallace
- C Marie-Claire
- C Wahlestedt
- CA Dackis
- CA McClung
- CB McCracken
- CP O'Brien
- CP O'Brien
- CP O'Brien
- D Maley
- D Marcellino
- D Morgan
- D Morgan
- D Morgan
- D Morgan
- David C S Roberts
- DC Roberts
- DC Roberts
- DJ Rohsenow
- Drake Morgan
- E Valjent
- EJ Nestler
- F Fumagalli
- FH Gawin
- G Paxinos
- GV Rebec
- IC Weave
- J Douglass
- JB Daunais
- JF Bowyer
- JL Lee
- JL Lee
- JN Jaworski
- JS Fosnaugh
- JW Grimm
- Kent E Vrana
- KJ Livak
- KK Szumlinski
- Kruti M Patel
- L Lu
- L Lu
- L Lu
- L Lu
- L Lu
- M Gossop
- M Werme
- MA Sutton
- Malinda E Lull
- Mandi Erwin
- MB Ghasemzadeh
- MS Brenz Verca
- MS Todtenkopf
- ND Volkow
- NH Mutschler
- NM Tsankova
- P Chomczynski
- P Fagergren
- P Taepavarapruk
- PW Kalivas
- R Moratalla
- R Sinha
- RC Risinger
- RG Hunter
- RH Zetterstrom
- Robert M Brucklacher
- SA Bennett
- SC Westwood
- SJ Ward
- SR Vorel
- TE Helton
- TE Thiele
- TY Roh
- WA Carlezon Jr
- Willard M Freeman
- WM Freeman
- WM Freeman
- WM Freeman
- WM Freeman
- Y Mateo
- Y Shaham
- YL Hurd
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Resolution of the ATLAS muon spectrometer monitored drift tubes in LHC Run 2
- Author
- Aad G
- Abbott B
- Abbott DC
- Abdinov O
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Achkar B
- Adachi S
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Ahmed WS
- Ai X
- Aielli G
- Akatsuka S
- Akesson TP
- Akilli E
- Akimov A
- Al Khoury K
- Alberghi GL
- Albert J
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexandre D
- Alexopoulos T
- Alfonsi A
- Alhroob M
- Ali B
- Alimonti G
- Alison J
- Alkire SP
- Allaire C
- Allbrooke BMM
- Allen BW
- Allport PP
- Aloisio A
- Alonso A
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- Alshehri AA
- Alvarez Estevez M
- Alvarez Piqueras D
- Alviggi MG
- Amaral Coutinho Y
- Ambler A
- Ambroz L
- Amelung C
- Amidei D
- Amor Dos Santos SP
- Amoroso S
- Amrouche CS
- An F
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anders JK
- Andreazza A
- Andrei V
- Anelli CR
- Angelidakis S
- Angerami A
- Anisenkov A
- Annovi A
- Antel C
- Anthony MT
- Antonelli M
- Antrim DJA
- Anulli F
- Aoki M
- Aparisi Pozo JA
- Arabidze G
- Araque JP
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- Argyropoulos S
- Arling J
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- Armitage LJ
- Armstrong A
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- Asimakopoulou EM
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- Astigarraga MEP
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- Atmani H
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- Avolio G
- Avramidou R
- Ayoub MK
- Azoulay AM
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- Batista SJ
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- Bobbink GJ
- Bobrovnikov VS
- Bocchetta SS
- Bocci A
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- Boerner D
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- Bogdanchikov AG
- Bohm C
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- Boldyrev AS
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- Boonekamp M
- Borecka-Bielska HM
- Borisov A
- Borissov G
- Bortfeldt J
- Bortoletto D
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- Boscherini D
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- Boumediene D
- Bourdarios CA
- Boutle SK
- Boveia A
- Boyd J
- Boye D
- Boyko IR
- Bozson AJ
- Bracinik J
- Brahimi N
- Brandt G
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- Braren F
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- Brau B
- Brau JE
- Brendlinger K
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- Bressler S
- Bret MC
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- Briglin DL
- Britton D
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- Brock I
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- Brooijmans G
- Brooks WK
- Brost E
- Broughton JH
- Bruncko D
- Bruni A
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- Bruni LS
- Bruno S
- Brunt BH
- Bruschi M
- Bruscino N
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- Bryngemark L
- Buanes T
- Buat Q
- Buchholz P
- Buckley AG
- Budagov IA
- Buescher V
- Bugge MK
- Bulekov O
- Burch TJ
- Burdin S
- Burgard CD
- Burger AM
- Burghgrave B
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- Buschmann E
- Bussey PJ
- Butler JM
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- Buttinger W
- Buzatu A
- Buzykaev AR
- Bylund OB
- Cabras G
- Cabrera Urban S
- Caforio D
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- Cairo VMM
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- Caloba LP
- Calvente Lopez S
- Calvet D
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- Calvet TP
- Calvetti M
- Camarda S
- Camarero Munoz D
- Camarri P
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- Campanelli M
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- Canesse A
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- Cardarelli R
- Cardillo FC
- Carli I
- Carli T
- Carlino G
- Carlson BT
- Carminati L
- Carney RMD
- Caron S
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- Castillo FL
- Castillo LRF
- Castro NF
- Catinaccio A
- Catmore JR
- Cattai A
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- Chakraborty D
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- Chan WY
- Chapman JD
- Chargeishvili B
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- Zhang L
- Zhang M
- Zhang R
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2019
- Field of study
The momentum measurement capability of the ATLAS muon spectrometer relies fundamentally on the intrinsic single-hit spatial resolution of the monitored drift tube precision tracking chambers. Optimal resolution is achieved with a dedicated calibration program that addresses the specific operating conditions of the 354 000 high-pressure drift tubes in the spectrometer. The calibrations consist of a set of timing offsets and drift time to drift distance transfer relations, and result in chamber resolution functions. This paper describes novel algorithms to obtain precision calibrations from data collected by ATLAS in LHC Run 2 and from a gas monitoring chamber, deployed in a dedicated gas facility. The algorithm output consists of a pair of correction constants per chamber which are applied to baseline calibrations, and determined to be valid for the entire ATLAS Run 2. The final single-hit spatial resolution, averaged over 1172 monitored drift tube chambers, is 81.7 ± 2.2 μm
Measurement of distributions sensitive to the underlying event in inclusive Z boson production in pp collisions at root s=13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott DC
- Abdinov O
- Abeling K
- Abhayasinghe DK
- Abidi SH
- AbouZeid OS
- Abraham NL
- Abramowicz H
- Abreu H
- Abud AA
- Abulaiti Y
- Acharya BS
- Achkar B
- Adachi S
- Adam L
- Adamczyk L
- Adamek L
- Adelman J
- Adersberger M
- Adiguzel A
- Adorni S
- Adye T
- Affolder AA
- Afik Y
- Agapopoulou C
- Agaras MN
- Aggarwal A
- Agheorghiesei C
- Aguilar-Saavedra JA
- Ahmadov F
- Ahmed WS
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- Aielli G
- Akatsuka S
- Akesson TP
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- Al Khoury K
- Alberghi GL
- Albert J
- Alconada Verzini MJ
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexandre D
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- Siegert F
- Sijacki D
- Silva Jr. M
- Silva Oliveira V M
- Silverstein SB
- Simion S
- Simioni E
- Simoniello R
- Simsek S
- Sinervo P
- Sinev NB
- Sioli M
- Siral I
- Sivoklokov SY
- Sjolin J
- Skorda E
- Skubic P
- Slawinska M
- Sliwa K
- Slovak R
- Smakhtin V
- Smart BH
- Smiesko J
- Smirnov N
- Smirnov SY
- Smirnov Y
- Smirnova LN
- Smirnova O
- Smith JW
- Smizanska M
- Smolek K
- Smykiewicz A
- Snesarev AA
- Snoek HL
- Snyder IM
- Snyder S
- Sobie R
- Soffa AM
- Soffer A
- Sogaard A
- Sohns F
- Sola JDB
- Soldatov EY
- Soldevila U
- Solis AL
- Solodkov AA
- Soloshenko A
- Solovyanov V O
- Solovyev V
- Sommer P
- Son H
- Song W
- Sopczak A
- Sopkova F
- Sotiropoulou CL
- Sottocornola S
- Soualah R
- Soukharev AM
- South D
- Spagnolo S
- Spalla M
- Span F
- Spangenberg M
- Sperlich D
- Spieker TM
- Spighi R
- Spigo G
- Spina M
- Spiteri DP
- Spousta M
- Stabile A
- Stamas BL
- Stamen R
- Stamenkovic M
- Stanecka E
- Stanek RW
- Stanislaus B
- Stanitzki MM
- Stankaityte M
- Stapf B
- Starchenko EA
- Stark GH
- Stark J
- Stark SH
- Staroba P
- Starovoitov P
- Staszewski R
- Stavropoulos G
- Stegler M
- Steinberg P
- Steinhebel AL
- Stelzer B
- Stelzer HJ
- Stelzer-Chilton O
- Stenzel H
- Stevenson TJ
- Stewart GA
- Stockton MC
- Stoicea G
- Stolarski M
- Stolte P
- Stonjek S
- Straessner A
- Strandberg J
- Strandberg S
- Strauss M
- Straz S
- Strizenec P
- Stroehmer R
- Strom DM
- Stroynowski R
- Strubig A
- Stucci SA
- Stugu B
- Stupak J
- Styles NA
- Su D
- Suchek S
- Sulin VV
- Sullivan MJ
- Sultan DMS
- Sultansoy S
- Sumida T
- Sun S
- Sun X
- Suruliz K
- Suster CJE
- Sutton MR
- Suzuki S
- Svatos M
- Swiatlowski M
- Swift SP
- Swirski T
- Sydorenko A
- Sykora I
- Sykora M
- Sykora T
- Ta D
- Tackmann K
- Taenzer J
- Taffard A
- Tafirout R
- Takai H
- Takashima R
- Takeda K
- Takeshita T
- Takeva EP
- Takubo Y
- Talby M
- Talyshev AA
- Tamir NM
- Tanaka J
- Tanaka M
- Tanaka R
- Tapprogge S
- Tarem S
- Tarna G
- Tartarelli GF
- Tas P
- Tasevsky M
- Tashiro T
- Tassi E
- Tavares Delgado A
- Tayalati Y
- Taylor AJ
- Taylor GN
- Taylor W
- Tee AS
- Tehrani FS
- Teixeira-Dias P
- Ten Kate H
- Teoh JJ
- Terada S
- Terashi K
- Terron J
- Terzo S
- Testa M
- Teuscher RJ
- Thais SJ
- Theveneaux-Pelzer T
- Thiele F
- Thomas DW
- Thomas JO
- Thomas JP
- Thompson AS
- Thompson PD
- Thomsen LA
- Thomson E
- Tian Y
- Tikhomirov VO
- Tikhonov YA
- Timoshenko S
- Tipton P
- Tisserant S
- Tobon CAM
- Todome K
- Todorova-Nova S
- Todt S
- Tojo J
- Tokar S
- Tokushuku K
- Tolley E
- Tomiwa KG
- Tomoto M
- Tompkins L
- Toms K
- Tong B
- Tornambe P
- Toro RC
- Torrence E
- Torres H
- Torres RET
- Tosciri C
- Toth J
- Tovey DR
- Traeet A
- Treado CJ
- Trefzger T
- Tresoldi F
- Tricoli A
- Trigger IM
- Trincaz-Duvoid S
- Trischuk W
- Trocme B
- Trofymov A
- Troncon C
- Trovatelli M
- Trovato F
- Truong L
- Trzebinski M
- Trzupek A
- Tsai F
- Tseng JC
- Tsiareshka V P
- Tsirigotis A
- Tsirintanis N
- Tsiskaridze V
- Tskhadadze EG
- Tsopoulou M
- Tsukerman II
- Tsulaia V
- Tsuno S
- Tsybychev D
- Tu Y
- Tudorache A
- Tudorache V
- Tulbure TT
- Tuna AN
- Turchikhin S
- Turgeman D
- Turner RJ
- Turra RT
- Tuts PM
- Tzamarias S
- Tzovara E
- Ucchielli G
- Uchida K
- Ueda I
- Ughetto M
- Ukegawa F
- Unal G
- Undrus A
- Unel G
- Ungaro FC
- Unno Y
- Uno K
- Urban J
- Urquijo P
- Usai G
- Usui J
- Uysal Z
- Vacavant L
- Vacek V
- Vachon B
- Vadla KOH
- Vaidya A
- Valderanis C
- Valente M
- Valentinetti S
- Valero A
- Valery L
- Vallance RA
- Vallier A
- Valls Ferrer JA
- Van Daalen TR
- Van Gemmeren P
- Van Vulpen I
- Vanadia M
- Vandelli W
- Vaniachine A
- Vannicola D
- Vari R
- Varnes EW
- Varni C
- Varol T
- Varouchas D
- Varvell KE
- Vasile ME
- Vasquez GA
- Vasquez JG
- Vazeille F
- Vazquez Furelos D
- Vazquez JGP
- Veatch J
- Vecchio V
- Veen MJ
- Veloce LM
- Veloso F
- Veneziano S
- Ventura A
- Venturi N
- Vera AMR
- Verbytskyi A
- Vercesi V
- Verducci M
- Vergara JCR
- Vergis C
- Verkerke W
- Vermeulen AT
- Vermeulen JC
- Vetterli MC
- Vickey T
- Viehhauser GHA
- Vigani L
- Villa M
- Villar DIN
- Vilucchi E
- Vincter MG
- Vinogradov VB
- Vishwakarma A
- Vittori C
- Vivarelli I
- Vogel M
- Vokac P
- von Buddenbrock SE
- Von Toerne E
- Vorobel V
- Vorobev K
- Vos M
- Vossebeld JH
- Vozak M
- Vranjes N
- Vrba V
- Vreeswijk M
- Vuillermet R
- Vukotic I
- Wagner P
- Wagner W
- Wagner-Kuhr J
- Wahlberg H
- Wakamiya K
- Walbrecht VM
- Walder J
- Walker R
- Walker SD
- Walkowiak W
- Wallangen V
- Wang AM
- Wang C
- Wang F
- Wang H
- Wang J
- Wang P
- Wang Q
- Wang R
- Wang SM
- Wang W
- Wang WT
- Wang WX
- Wang Y
- Wang Z
- Wanotayaroj C
- Warburton A
- Ward CP
- Wardrope DR
- Warrack N
- Washbrook A
- Watson AT
- Watson MF
- Watts G
- Waugh BM
- Webb AF
- Webb S
- Weber C
- Weber MS
- Weber SA
- Weber SM
- Weidberg AR
- Weingarten J
- Weirich M
- Weiser C
- Wells PS
- Wenaus T
- Wengler T
- Wenig S
- Wermes N
- Werner MD
- Werner P
- Wessels M
- Weston TD
- Whalen K
- Whallon NL
- Wharton AM
- White A
- White AS
- White MJ
- Whiteson D
- Whitmore BW
- Wickens FJ
- Wiedenmann W
- Wielers M
- Wieseotte N
- Wiglesworth C
- Wiik-Fuchs LAM
- Wilk F
- Wilkens HG
- Wilkins LJ
- Williams HH
- Williams S
- Willis C
- Willocq S
- Wilson JA
- Wingerter-Seez I
- Winkels E
- Winklmeier F
- Winston OJ
- Winter BT
- Wittgen M
- Wobisch M
- Wolf A
- Wolf TMH
- Wolff R
- Wolker RW
- Wollrath J
- Wolter MW
- Wolters H
- Wong VWS
- Woods NL
- Worm SD
- Wosiek BK
- Wozniak KW
- Wraight K
- Wu SL
- Wu X
- Wu Y
- Wyatt TR
- Wynne BM
- Xella S
- Xi Z
- Xia L
- Xu D
- Xu H
- Xu L
- Xu T
- Xu W
- Xu Z
- Yabsley B
- Yacoob S
- Yajima K
- Yallup DP
- Yamaguchi D
- Yamaguchi Y
- Yamamoto A
- Yamanaka T
- Yamane F
- Yamatani M
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang HJ
- Yang HT
- Yang S
- Yang X
- Yang Y
- Yao W
- Yap YC
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yeletskikh I
- Yexley MR
- Yigitbasi E
- Yildirim E
- Yildiz HD
- Yorita K
- Yoshihara K
- Young C
- Young CJS
- Yu J
- Yuan R
- Yue X
- Yuen SPY
- Zabinski B
- Zacharis G
- Zaffaroni E
- Zahreddine J
- Zaitsev AM
- Zakareishvili T
- Zakharchuk N
- Zambito S
- Zanzi D
- Zaripovas DR
- Zeissner V S
- Zeitnitz C
- Zemaityte G
- Zeng JC
- Zenin O
- Zenis T
- Zerwas D
- Zgubic M
- Zhang DF
- Zhang F
- Zhang G
- Zhang H
- Zhang J
- Zhang L
- Zhang M
- Zhang R
- Zhang X
- Zhang Y
- Zhang Z
- Zhao P
- Zhao Y
- Zhao Z
- Zhemchugov A
- Zheng Z
- Zhong D
- Zhou B
- Zhou C
- Zhou M
- Zhou MS
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu HL
- Zhu J
- Zhu Y
- Zhuang X
- Zhukov K
- Zhulanov V
- Zieminska D
- Zimine I N
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zivkovic L
- Zobernig G
- Zoccoli A
- Zoch K
- Zorbas TG
- Zou R
- Zu Theenhausen HM
- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2019
- Field of study