44 research outputs found
Katherine Fishburn, Doris Lessing: Life, Work, and Criticism
- Author
- Publication venue
- International Fiction Review
- Publication date
- 06/06/1989
- Field of study
Reading the Crisis: The Polemics of Salman Rushdie's "The Satanic Verses"
- Author
- Publication venue
- The Johns Hopkins University Press
- Publication date
- 01/10/1989
- Field of study
Shirley Neuman, ed., Another Country: Writings by and about Henry Kreisel
- Author
- Publication venue
- International Fiction Review
- Publication date
- 01/01/1988
- Field of study
George Orwell and Iris Murdoch: Patterns of Power
- Author
- Publication venue
- International Fiction Review
- Publication date
- 06/06/1986
- Field of study
Peter J. Conradi, Iris Murdoch: The Saint and the Artist
- Author
- Publication venue
- International Fiction Review
- Publication date
- 06/06/1987
- Field of study
SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues
- Author
- Abd Elghafar Mohamed S.
- Abdel-Aziz Mahmoud
- Abdollahi Hamed
- Abdullah Tala
- Abecasis Goncalo R.
- Abedalthagafi Malak
- Abul-Husn Noura S.
- Acquilini Donatella
- Adams Emma L.
- Adamsara Alireza
- Adeleye Olumide
- Adra Darin
- Afilalo Jonathan
- Afilalo Marc
- Afrasiabi Zaman
- Agüero Daiana
- Ahmadi Saeideh
- Aksentijevich Alexandra
- Al Harthi Fawz
- Al Mutairi Amal
- Al-Afghani Hani
- Al-Awdah Laila
- Alaamery Manal
- Alahmadey Ziab Z.
- Alaverdian Diana
- Alavere Helene
- Albader Anoud
- Albaiceta Guillermo M.
- Albakri Jehad K.
- AlBardis Hadeel
- Albeladi Maha
- Albesher Nour
- Albrich Werner
- AlDhawi Nouf
- Aleagha Afshar Etemadi
- Alghamdi Bader
- Alghamdi Jahad
- Ali Altaf
- Aliannejad Rasoul
- Aljawini Nora
- AlJohani Sameera
- Alkwai Sarah
- Allos Raili
- AlMalik Abdulaziz
- Almalki Faisal
- Almohammed Iman
- Almutairi Mansour
- Alotaibi Sara
- Alowayn Albandary M.
- Alqahtani Saleh
- Alqubaishi Fatimah
- Alrashed May
- Alshareef Abdulraheem
- Alsolm Ebtehal
- Alswailm Moneera
- AlZahrani Deema
- Amirsavadkouhi Ali
- Amitrano Sara
- Andolfo Immacolata
- Andretta Francesca
- Andreucci Elena
- Andrews Shea J.
- Andrews Shea J.
- Andrews Shea J.
- Anedda Federico
- Anemoli Valentina
- Anne Feng Yen-Chen
- Annis Aubrey
- Antinori Andrea
- Antoni Melania Degli
- Aprile von Hohenstaufen Kathrin
- Arabi Yaseen M.
- Armstrong Jacob
- Arning Nicolas
- Arranz Maria J.
- Arribas Elisa
- Arthur Timothy D.
- Artuso Rosangela
- Arumugam Prabhu
- Ascolillo Steven
- Atkinson Elizabeth G.
- Aucella Filippo
- Auld Daniel
- Azarzar Samira
- Åsvold Bjørn Olav
- Bachetti Tiziana
- Balaconis Mary K.
- Baldassarri Margherita
- Ball Catherine A.
- Baltzell Asher Haug
- Band Gavin
- Bandini Maria
- Baraka Dona
- Baras Aris
- Baratti Stefano
- Barbieri Chiara
- Bargagli Elena
- Barhoush Eman
- Barnes Kathleen C.
- Baroni Silvia
- Bartels Meike
- Bassetti Matteo
- Batini Chiara
- Baya Nikolas
- Beck Andrew
- Beckmann Noam D.
- Bedini Josep L.
- Bee Catherine E.
- Beguin Yves
- Belbin Gillian M.
- Belhaj Yasmine
- Beligni Giada
- Belisle Alexandre
- Belli Mary Ann
- Below Jennifer
- Benetti Elisa
- Bennett David
- Bergantini Laura
- Bergomi Paola
- Berkowitz Nathan
- Bernardo David
- Bibert Stéphanie
- Biscarini Filippo
- Blay Natalia
- Bochud Pierre-Yves
- Boillat Noémie
- Bottà Giordano
- Bouab Meriem
- Boughton Andrew P.
- Bradford Yuki
- Branka Vulesevic Nardin Rezk
- Brassard Nathalie
- Brenner Bluma
- Britvan Bari
- Brumpton Ben M.
- Bruno Raffaele
- Bruttini Mirella
- Bryant Sam
- Bryant Sam
- Buring Julie E.
- Busani Stefano
- Bussotti Maurizio
- Butler-Laporte Guillaume
- Butler-Laporte Guillaume
- Butterworth Adam S.
- Buxbaum Joseph D.
- Cal-Sabater Paloma de la
- Caldarelli Gian Piero
- Callier Shawneequa
- Cameli Paolo
- Campbell Archie
- Campbell Archie
- Canaccini Anna
- Cantarini Luca
- Cantor Michael N.
- Capasso Mario
- Capitani Katia
- Cappelli Silvia
- Carella Massimo
- Carey Dave J.
- Carreras Anna
- Carriero Miriam Lucia
- Castaño-Vinyals Gemma
- Castelli Francesco
- Castori Marco
- Catena Emanuele
- Caulfield Mark J.
- Cárcel-Márquez Jara
- Ceri Stefano
- Chamnanphon Monpat
- Chan Georgia
- Chang Xiao
- Chang Xiao
- Chariyavilaskul Pajaree
- Charney Alexander W.
- Chasman Daniel I.
- Chassé Michaël
- Chaudhary Kumardeep
- Chavan Sameer
- Chen Hung-Hsin
- Cheng Nathan
- Chetruengchai Wanna
- Chittoor Geetha
- Cho Judy H.
- Cho Kelly
- Choi Sam
- Churchhouse Claire
- Chwialkowska Karolina
- Claassen Sabine
- Claringbould Annique
- Coignet Marie
- Coiro Gabriella
- Collins Brett L.
- Colobrán Roger
- Colombo Riccardo
- Conticini Edoardo
- Cordioli Mattia
- Cordioli Mattia
- Cordioli Mattia
- Cordioli Mattia
- Cordioli Mattia
- Cordioli Mattia
- Cordioli Mattia
- Cordioli Mattia
- Corridi Marta
- Cortés Beatriz
- Cossarizza Andrea
- Coto Eliecer
- Coviello Domenico A.
- CRiPSI null
- Croci Leonardo
- Croci Susanna
- Crook Derrick W.
- Crooks Kristy
- Crotti Lia
- Cullell Natalia
- Cusick Caroline
- Daga Sergio
- Dalmau David
- Daly Mark
- Danesh John
- Darcis Gilles
- Daya Michelle
- de Cid Rafael
- de Felipe Mimbrera Alicia
- de geus Eco (E. J. C. )
- De Vivo Oreste
- DeDiego Marta L.
- Deelen Patrick
- Dei Simona
- Della Monica Matteo
- Desanctis Elena
- Di Angelantonio Emanuele
- Di Biagio Antonio
- Di Domenico Paolo
- Di Pietro Massimo
- Di Sarno Laura
- Dietl Beatriz
- Do Ron
- Dobaño Carlota
- Doddato Gabriella
- Domingo Carlos
- Domínguez-Mayoral Anna
- Donati Alice
- Donner Kati
- Durand Madeleine
- D’Alessandro Miriana
- D’Antonio Matteo
- D’Antonio-Chronowska Agnieszka
- D’Arminio Monforte Antonella
- D’Mellow Kenton
- Earle Sarah G.
- Eid Mohammed A.
- El-Jawhari Jehan J.
- El-Lawaty Walaa M.
- El-shanshory Mohamed R.
- El-Sherbiny Yasser M.
- Elhadidy Tamer A.
- Elnagdy Marwa H.
- Eltoukhy Madonna M.
- Emiliozzi Arianna
- Emma Duncan
- Erard Véronique
- Esko Tõnu
- Fabbiani Massimiliano
- Falcone Marco
- Fallerini Chiara
- Farré Xavier
- Fava Francesca
- Fawns-Ritchie Chloe
- Fawns-Ritchie Chloe
- Fawzy Mohammad S.
- Felemban Walaa A.
- Feri Marco
- Fernandez-Cadenas Israel
- Ferreira Manuel A. R.
- Ferri Claudio
- FHoGID null
- Finer Sarah
- FinnGen null
- Finucane Hilary
- Fiorentino Giuseppe
- Fiz-López Aida
- Forgetta Vincenzo
- Forgetta Vincenzo
- Fowler Tom
- Francesco Bianchi Antonio Perrella
- Franchi Federico
- Francisci Daniela
- Franco Giulianini
- Frazer Kelly A.
- Frediani Bruno
- Free Robert C.
- Frippiat Frederic
- Frithiof Robert
- Frullanti Elisa
- Furini Simone
- Gabbi Chiara
- Gabrieli Arianna
- Gaddis Michael
- Galván-Femenía Iván
- Ganna Andrea
- Ganna Andrea
- Garcia-Aymerich Judith
- García-Clemente Marta
- García-Madrona Sebastian
- Gass Matthew C.
- Gatti Francesca
- Gaziano J. Michael
- Genes &
- Georges Michel
- Gettler Kyle
- Ghosh Biswarup
- Giannattasio Ferdinando
- Gignoux Christopher R.
- Giliberti Annarita
- Giorli Alessia
- Giot Jean-Baptiste
- Girardis Massimo
- Girshick Ahna
- Glessner Joseph R.
- Glessner Joseph T.
- Gofflot Stéphanie
- Goldstein Jacqueline I.
- Gomez Juan
- González-Villa Esther
- Gori Marco
- Grassi Davide
- Green Robert C.
- Griffiths Christopher J.
- Grip Jonathan
- Guarnaccia Alessandra
- Guerrini Susanna
- Guidelli Luca
- Guindo-Martinez Marta
- Guiot Julien
- Guntz Julien
- Gupta Rahul
- Guturu Harendra
- Guyatt Anna L.
- Guzman Charlotte
- Hakonarson Hakon
- Hakonarson Hakon
- Halawani Roaa T.
- Harerimana Nadia
- Harris Jennifer R.
- Hasanato Rana
- Hayward Caroline
- Hayward Caroline
- Health Research Team null
- Hegazy Mohamed A. F.
- Helgeland Øyvind
- Henry Danielle
- Hensen Kati
- Hiester Liam L.
- Hirankarn Nattiya
- Ho Yuk-Lam
- Hoggart Clive
- Hollox Edward J.
- Hong Eurie L.
- Horowitz Julie E.
- Hosseini Abdolmajid
- Hottenga Jouke Jan
- Huang Qin Qin
- Huckins Laura M.
- Huffman Jennifer E.
- Hultström Michael
- Hunt Karen A.
- Huynen Pascale
- Hveem Kristian
- Iglesias Lara Lloret
- Ikram M. Arfan
- Iolascon Achille
- Itan Yuval
- Jacques Jessica
- Jantarabenjakul Watsamon
- Jiménez-Xarrié Elena
- John Catherine
- Jordan Daniel M.
- Josyula Navya Shilpa
- Jung Junghyun
- Justice Anne E.
- Kallaste Anne
- Kamdar Dhryata
- Kanai Masahiro
- Kanai Masahiro
- Kanai Masahiro
- Karczewski Konrad J.
- Karjalainen Juha
- Karlson Elizabeth W.
- Karp Avromie
- Kaufmann Daniel E.
- Kaunisto Mari
- Keller Katherine
- Kenny Eimear E.
- Kerr Shona M.
- Khafaga Walid T.
- Khattab Amin K.
- Kimchi Nofar
- King Daniel
- Kisand Kai
- Kivinen Katja
- Knight Spencer
- Koelling Nils
- Kogevinas Manolis
- Koskelainen Sami
- Kosmicki Jack A.
- Kousathanas Athanasios
- Kristiansson Kati
- La Rovere Maria Teresa
- Laane Edward
- Labkowsky Alexander
- Laisk Triin
- Lambermont Bernard
- Lanting Pauline
- Lathrop G. Mark
- Lauren Petty E.
- Laurent Laetitia
- Läll Kristi
- Leader Joseph B.
- Lee Paul H.
- Lee Yunsung
- LeFaive Jonathon
- Lena Fabio
- Lepage Pierre
- Lepamets Maarja
- Levy Tess
- Léonard Philippe
- Li Binglan
- Li Kevin W.
- Li Rui
- Liao Rachel G.
- Lin Shang-Kuan
- Lipcsey Miklos
- Lista Mirjam
- Llucià-Carol Laia
- Lo Rizzo Caterina
- Loos Ruth J. F.
- Lopera Esteban
- Lorubbio Maria
- Lozano Francisco
- Lu Wenhan
- Lucas Anastasia
- Luchi Sauro
- Ludovisi Serena
- Maggiolo Franco
- Magnus Per
- Mahmoud Ebrahim S.
- Malaise Olivier
- Mamlouk Noor
- Mancarella Sandro
- Mandalà Marco
- Mangino Massimo
- Mangul Serghei
- Manson JoAnn E.
- Mantovani Stefania
- Marcantonio Simona
- Marciano Carmen
- Mari Francesca
- Maricic Tomislav
- Marike Boezen Lude Franke
- Martin Alicia R.
- Martin Hilary C.
- Martinelli Enrico
- Martí-Fàbregas Joan
- Martín-Nalda Andrea
- Martínez Alba Parra
- Masjuan Jaime
- Mason Dan
- Massadeh Salam
- Masucci Luca
- Matsui Hiroko
- Mazzei Maria Antonietta
- Márquez Leonardo
- Mägi Reedik
- McCormick Joseph B.
- McCurdy Shannon
- Medina-Gomez Carolina
- Meigs James B.
- Meloni Ilaria
- Menatti Elisabetta
- Mencarelli Maria Antonietta
- Menéndez-Valladares Paloma
- Mercader Josep
- Mercader Josep Maria
- Merla Giuseppe
- Metsalu Kristjan
- Metspalu Andres
- Meuris Christelle
- Milani Lili
- Miraglia Federica Gaia
- Mirshahi Tooraj
- Misset Benoit
- Moahmed Hanteera S.
- Mohamed Attia A. S.
- Mohseni Moghaddam Seyed Behrooz
- Mondelli Mario Umberto
- Montagnani Francesca
- Mooser Vincent
- Moreno Victor
- Morris Marcela
- Morrison David R.
- Moutschen Michel
- Moutsianas Loukas
- Muiño Elena
- Murphy Shawn N.
- Mussini Cristina
- Naaber Paul
- Naderpour Zeinab
- Nadkarni Girish N.
- Nakanishi Tomoko
- Nakanishi Tomoko
- Neale Benjamin M.
- Nencioni Cesira
- Neofytos Dionysios
- Nguyen Huy
- Nguyen Jennifer P.
- Niavarani Ahmadreza
- Niblo Kristi
- Niemi Mari E. K.
- Niemi Mari E. K.
- Niemi Mari E. K.
- Niemi Mari E. K.
- Niemi Mari E. K.
- Nilaratanakul Voraphoj
- Nivard Michel (M. G. )
- Nkambul Lindo
- Nkambul Lindokuhle
- Nkambul Lindokuhle
- Nkambule Lindokuhle
- Nkambule Lindokuhle
- North Kari
- Noto Keith
- Nussle Semira Gonseth
- Odhams Christopher A.
- Ognibene Agostino
- Okasha Kamal
- Oliveira Maureen
- Ori Anil P. S.
- O’Connell Anne Marie
- O’Donnell Christopher J.
- O’Reilly Paul
- P-PredictUs null
- Paciosi Francesco
- Paciosi Francesco
- Packer Richard J.
- Palmer Duncan S.
- Palmieri Maria
- Palotie Aarno
- Pancrazzi Alessandro
- Panese Sandro
- Parati Gianfranco
- Parisi Saverio Giuseppe
- Park Danny
- Parravicini Pierpaolo
- Partha Raghavendran
- Pasko Dorota
- Pathak Gita A.
- Pathak Gita A.
- Pavlovic Milos
- Peloso Gina
- Perez Emma F.
- Perez-Tur Jordi
- Perna Rita
- Perola Markus
- Peruggia Michael
- Pessina Gloria
- Pesukova Jaana
- Peterson Pärt
- Petitjean Louis
- Petrocelli Paola
- Phokaew Chureerat
- Piacentini Paolo
- Picchiotti Nicola
- Pigazzini Sara
- Pigazzini Sara
- Pigazzini Sara
- Pigazzini Sara
- Pinoli Pietro
- Pinto Anna Maria
- Pirinen Matti
- Piscopo Carmelo
- Planas Anna M.
- Polikowski Hannah
- Polimanti Renato
- Polymeropoulos Christos
- Polymeropoulos Mihael H.
- Polymeropoulos Vasilios
- Pongpanich Monnat
- Porteous David J.
- Porteous David J.
- Poscente Monica
- Preuss Michael
- Przychodzen Bartlomiej P.
- Putchareon Opass
- Puthanakit Thanyawee
- Puusepp Mairo
- Quinodoz Mathieu
- Quiros-Roldan Eugenia
- Rader Daniel
- Rafaels Nicholas
- Raggi Pamela
- Ragoussis Jiannis
- Rahmouni Souad
- Raimondi Francesco
- Rancan Ilaria
- Rand Kristin
- Ravaglia Sabrina
- RegCOVID null
- Reimann Ene
- Rendon Augusto
- Renieri Alessandra
- Rhead Brooke
- Rhodes Daniel
- Richards J. Brent
- Richards J. Brent
- Richmond Anne
- Richmond Anne
- Rico Veronica
- Ridker Paul M.
- Ringmets Inge
- Ripamonti Diego
- Ripatti Samuli
- Ritchie Marylyn D.
- Riva Agostino
- Rivolta Carlo
- Rizzi Marco
- Roberts Genevieve
- Robles Veronica
- Rogne Tormod
- Rojo Silvia
- Romani Davide
- Rooyackers Olav
- Rossetti Barbara
- Rudkin Justine K.
- Ruiz Luong
- Ruiz-Jaén Francisca
- Ruotsalainen Sanni
- Rusconi Stefano
- Russo Roberta
- Sabrina Ravaglia
- Saeedi Morteza
- Safieh Leen Abu
- Salerni Lorenzo
- Salib Irene
- Samir Amr
- Sanarico Maurizio
- Sanguinetti Maurizio
- Sarma Gopal
- Sarzi-Braga Simona
- Satterstrom F. Kyle
- Sauvage Anne-Sophie
- Sawaji Mona
- Scaggiante Renzo
- Scala Raffaele
- Schadt Eric E.
- Schiaroli Elisabetta
- Schurr Erwin
- Scolletta Sabino
- Scott Richard H.
- Scotton Pier Giorgio
- Sealfon Stuart C.
- Sebastian Zöllner Brooke Wolford
- Sebra Robert P.
- Seed Cotton
- Segala Francesco Vladimiro
- Segura Tomás
- SeroCOVID null
- Serra-Llovich Alex
- Serrano-Heras Gemma
- Sesso Howard D.
- Shahin Doaa
- Sharififard Bahareh
- Shaw Douglas M.
- Shortt Jonathan
- Shotelersuk Vorasuk
- Shrine Nick
- Siano Matteo
- Sloofman Laura G.
- Smieszek Sandra P.
- Smith Albert V.
- Smoller Jordan W.
- Sobh Ali
- Sodsai Pimpayao
- Soler Pere
- Solligard Erik
- Solomonson Matthew
- Solomonson Matthew
- Soranzo Nicole
- Soriano Alex
- Spargi Genni
- Spector Tim D.
- Spencer Chris C. A.
- Spertilli Chiara
- Squeo Gabriella Maria
- Starkopf Joel
- Stella Alessandra
- Stevens Christine
- Stevens Christine
- Stuckey Alex
- Suardi Claudia
- Suchartlikitwong Pintip
- Suh Noémie
- Suliman Bandar A.
- Sumoy Lauro
- Sun Yan V.
- Suttichet Thitima B.
- Tabri Jekaterina
- Tacconi Danilo
- Tadi Hengameh Ansari
- Tamm Anu
- Tanfoni Marco
- Tang Lara
- Tardif Nicolas
- Tavecchia Luisa
- Tenesa Albert
- Thompson Ryan C.
- Thys Marie
- Timmers Paul R. H. J.
- Tiseo Giusy
- Tita Rossella
- Tobin Martin D.
- Tommasi Andrea
- Torky Mohamed S.
- Torrents David
- Torvorapanit Pattama
- Trankiem Amy
- Trembath Richard C.
- Trivedi Bhavi
- Trogstad Lill-Iren S.
- Trotta Tullio
- Tsao Phil
- Tselios Chris
- Tsuo Kristin
- Tumbarello Mario
- Turley Patrick
- Uitterlinden Andre G.
- Underwood Slayton J.
- Vaghi Massimo
- Valente Serafina
- Valentino Floriana
- van Blokland Irene
- van Heel David A.
- Vecchia Marco
- Veerapen Kumar
- Venn Laura D.
- Venturelli Sophie
- Vergori Alessandra
- Verma Anurag
- Verma Shefali S.
- Verzuri Agnese
- Villalonga Joan Montaner
- Vincenti Antonella
- Voide Cathy
- Von Frenckell Christian
- Vonk Judith. M.
- Wain Louise V.
- Walker Susan
- Walters Raymond K.
- Wang Jiongming
- Wang Xueyang
- Wanying Zhu
- Warmerdam Robert
- Weiss Scott T.
- Wicks Stephen J.
- Willer Cristen
- Williams Alexander T.
- Wilson Daniel J.
- Wilson James F.
- Wolford Brooke
- Wolford Brooke
- Woolley Ann E.
- Wright John
- Wyllie David H.
- Xue Xiaoqing
- Yadav Ashish
- Yassen Amr M.
- Zanella Isabella
- Zeberg Hugo
- Zguro Kristina
- Zhang Miao
- Zhao Jing Hua
- Zhou Wei
- Zhou Wei
- Zlatopolsky Menachem
- Zucchi Patrizia
- Zyndorf Marissa
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to
genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility
and 19 for COVID-19 disease severity. Four of these 23 loci likely have an ethnicity-specific component.
Genome-wide association study (GWAS) signals in 11 loci colocalize with expression quantitative trait loci
(eQTLs) associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene),
including lung, brain, heart, muscle, and skin as well as the digestive system and immune system. We perform
genetic fine mapping to compute 99% credible SNP sets, which identify 10 GWAS loci that have eight or fewer
SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the
diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome, affecting gene expression levels in a wide variety of tissue types
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
- Author
- Aamir Faiqa Binte
- Aamir Syed Roohan
- Ababneh Adnan
- Abbal Muhammad Anas
- Abbas Ahmed M
- Abbas Mostafa
- Abd-Albain Montasir A
- Abdalei Abdulwahab
- Abdalla Ahmed
- Abdalla Ahmed Yassir
- Abdalla Mohamed Galal Ali
- Abdalla Zainab
- Abdallah Mohamed M
- Abdalmahmoud Noon Ezzeldien
- Abdalsadeg Rowa
- Abdelaal Ahmed M
- Abdelbagi Alnazeer Y
- Abdelbaky Mostafa
- Abdelbaset Doaa
- AbdElbaset Esraa
- Abdelbast Menhag
- Abdelfatah Mohammed Abdelnasser
- Abdelgawad Samia
- Abdelhamid Mohamed M
- Abdeljaber Mahmoud
- Abdelkhalig Mubarak
- Abdelmaksoud Mohamed
- Abdelmeguid Rana
- Abdelmelek Dhia Errahmane
- Abdelnaeam Samah
- Abdelnasser Mohammad K
- Abdelrahim Najwa
- Abdelrahman Amira
- Abdelrahman Ayman
- Abdelsalam Hebatalla
- Abdelsamed Enas Abdelbaset
- Abdelwahab Khaled
- Abdoun Meriem
- Abdulali Fatima
- Abdulaziz Mohamed
- Abdulla Dheba Almukhtar
- Abdullah Bahiyah
- Abdullah Bahiyah
- Abdullah Walaa
- Abdullahi Habiba Ibrahim
- Abdulrahman Ahmed
- Abdulrasheed Lubabatu
- Abdulwahed Eman
- Abdulwahed Eman
- Abeysirigunawardana Dewmi
- Abidin Muhammad Fihmi Zainal
- Abiola Olukayode
- Abiyere Henry
- Abodina Ahmed Mohammed
- Aboelela Reham
- AboElfarh Hadeer Elsaeed
- Aboudlal Husein
- AbouHiekal Osama
- Aboulfotouh Ahmed
- Abozid Anwaar
- Abubaker Noora
- Abubaker Noora
- Abufanas Asma
- Abughanima Mahmoud
- Abuhashem Shehab
- Abulafia Daniel
- Abushaala Fatima
- Abushanab Khaled
- AbuShawareb Issa
- Abuuqteish Hamza
- Abuzaho Amany
- Achem Arome
- Adam Eithar
- Adam Mohammed
- Adam Mohammed A
- Addalla Mohamed
- Addley Jordan
- Adeleye Gbadebo
- Adeniyi Adebayo
- Adewole Nathaniel
- Adeyemo Olabisi
- Adeyeye Ademola
- Adeyeye Ademola
- Adly Michael
- Adnan Siti Nasyirah Nisya
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adze Joel Amwe
- Afeikhena Ehis
- Agida Teddy
- Agilla Hamza
- Agnew Emilie
- Agu Joy Onyekachi
- Ahmad Zatul Akmar
- Ahmed Abdalla
- Ahmed Ahmed
- Ahmed Ahmed
- Ahmed Alaaaldeen
- Ahmed Entisar
- Ahmed Habeeba
- Ahmed Hatem
- Ahmed Reem
- Ahmed Rehab
- Ahmed Rihab
- Ahmed Rogia Ahmed Abdalla
- Ahmed Ruaa
- Ahmed Sharwany
- Ahmed Uzair
- Ahmed Wahiba
- Ahmeed Sultan
- Airede Lydia Regina
- Aitchison Lori
- Ajredini Mirac
- Ajulo Adeshina A
- Akaba Godwin
- Akasha Mazin
- Akbar Maha Ghulam
- Akbuz Seyma Orcan
- Akdere Hakan
- Akın Bilge
- Akkaya Ege Nur
- Akpamgbo Chukwunonso Nnamdi
- Akwaisah Ayoub
- Al Hammoud Amr
- Al Rawashdeh Toka
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- Yeung Kar Long
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- Yildirim Yasemin
- Yildiz Ahmet
- Yıldız Berkay
- Yilmaz Hakan
- Yin Chonghao
- Ying Geoffrey
- Yodkitydomying Chatnapa
- Yong Nathania
- Yoon Si Woo
- You Ha Seong
- Young Simon
- Young Stevie
- Younus Khadijah
- Yousif Fatima Imad
- Yousri Mohamed
- Youssef Ahmed A
- Youssef Arkan
- Yu Hoi Hang
- Yu Victor
- Yuan Grace
- Yue Bosco
- Yue Tiffany
- Yunos Mohamed Haseef Mohamed
- Yusuf Stephen
- Yuzgec Ayse Nilufer
- Zachomitros Fotios
- Zaed Moahmed
- Zafar Fatima
- Zaghloul Ahmed
- Zaheer Adil
- Zaidi Faseeh
- Zain Ahmad
- Zakaria Ahmed
- Zakaria Andee Dzulkarnaen
- Zakaria Mohd Zaim
- Zalloum Jihad
- Zamanbandhon Bushra
- Zambon Mattia
- Zapsalis Konstantinos
- Zargar Kamran
- Zarzour Mohamed A
- Zeng Raymond
- Zeng Raymond
- Zengin Kagan
- Zertuche Juventino Tadeo Guerrero
- Zhang Caitlin
- Zhang Edward
- Zhang Shane
- Zhang Yichi
- Zhao Hailin
- Zheng Helen
- Zhou Karen
- Zhou Yida
- Ziergiebel Felix
- Zou Peishan
- Zuylekom Kate Van
- Zuylekom Katie Van
- Zwain Yasir Adnan
- Zyul'korneeva Sof'ya
- Aladna Abdallah
- Aljoumaa Abdullah
- Nawfal Hamdi
- Niazi Ammar
- Publication venue
- Publication date
- 01/01/2024
- Field of study
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Use of anticoagulants and antiplatelet agents in stable outpatients with coronary artery disease and atrial fibrillation. International CLARIFY registry
- Author
- A. L. R. Ng
- Abardia Oliva F. J.
- Abdel Malak S.
- Abdel Wahab H.
- Abdul Kareem B. B.
- Abdul Manap H.
- Abdul Rahim A. A.
- Abdulkader F.
- Abdulla A. H. K.
- AbdulWahab M. Z.
- Abduvalieva V.
- Abele S.
- Aboyans V.
- Abreu P. E.
- Adam-Blanpain M.
- Adamaszek K.
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- Adamkiewicz-Piejko A.
- Adda M.
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- Akbar M.
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- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2015
- Field of study
Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
- Author
- Abate Yohannes Habtegiorgis
- Abbas Jaffar
- Abbasi Madineh Akram
- Abbasian Mohammadreza
- Abbastabar Hedayat
- Abd-Rabu Rami
- Abdelmasseh Michael
- Abdollahi Mohammad
- Abdollahi Mozhan
- Abdollahifar Mohammad-Amin
- Abdulah Deldar Morad
- Abdullahi Auwal
- Abedi Aidin
- Abedi Vida
- Abeldaño Zuñiga Roberto Ariel
- Abidi Hassan
- Abiodun Olumide
- Aboagye Richard Gyan
- Abolhassani Hassan
- Aboyans Victor
- Abrha Woldu Aberhe
- Abu-Gharbieh Eman
- Abualhasan Ahmed
- Aburuz Salahdein
- Adamu Lawan Hassan
- Addo Isaac Yeboah
- Adebayo Oladimeji M
- Adekanmbi Victor
- Adekiya Tayo Alex
- Adikusuma Wirawan
- Adnani Qorinah Estiningtyas Sakilah
- Adra Saryia
- Afework Tsion
- Afolabi Aanuoluwapo Adeyimika
- Afraz Ali
- Afzal Saira
- Aghamiri Shahin
- Agodi Antonella
- Agyemang-Duah Williams
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Danish
- Ahmad Sajjad
- Ahmadzade Amir Mahmoud
- Ahmed Ali
- Ahmed Ayman
- Ahmed Haroon
- Ahmed Jivan Qasim
- Ahmed Luai A
- Ahmed Muktar Beshir
- Ahmed Syed Anees
- Ajami Marjan
- Aji Budi
- Ajumobi Olufemi
- Akade Seyed Esma'il
- Akbari Morteza
- Akbarialiabad Hossein
- Akhlaghi Shiva
- Akinosoglou Karolina
- Akinyemi Rufus Olusola
- Akonde Maxwell
- Al Hasan Syed Mahfuz
- AL-Ahdal Tareq Mohammed Ali
- Al-amer Rasmieh Mustafa
- Al-Gheethi Adel Ali Saeed
- Al-Omari Basem
- Al-Shahi Salman Rustam
- Al-Tawfiq Jaffar A
- Al-Worafi Yaser Mohammed
- Alahdab Fares
- Albashtawy Mohammed
- AlBataineh Mohammad T
- Aldawsari Khalifah A
- Alemi Hediyeh
- Alemi Sharifullah
- Algammal Abdelazeem M
- Alhalaiqa Fadwa Alhalaiqa Naji
- Alhassan Robert Kaba
- Ali Abid
- Ali Endale Alemayehu
- Ali Liaqat
- Ali Mohammed Usman
- Ali Musa Mohammed
- Ali Rafat
- Ali Shahid
- Ali Syed Shujait Shujait
- Ali Zahid
- Alif Sheikh Mohammad
- Alimohamadi Yousef
- Aliyi Ahmednur Adem
- Aljofan Mohamad
- Aljunid Syed Mohamed
- Alladi Suvarna
- Almazan Joseph Uy
- Almustanyir Sami
- Alqahtani Jaber S
- Alqasmi Ibrahim
- Alqutaibi Ahmed Yaseen
- Altaany Zaid
- Altirkawi Khalid A
- Alvis-Guzman Nelson
- Aly Hany
- Aly Safwat
- Alzoubi Karem H
- Amani Reza
- Amindarolzarbi Alireza
- Amiri Sohrab
- Amirzade-Iranaq Mohammad Hosein
- Amu Hubert
- Amugsi Dickson A
- Amusa Ganiyu Adeniyi
- Amzat Jimoh
- Ancuceanu Robert
- Anderlini Deanna
- Anderson David B
- Andrei Catalina Liliana
- Androudi Sofia
- Angappan Dhanalakshmi
- Angesom Teklit W
- Anil Abhishek
- Ansari-Moghaddam Alireza
- Anwer Razique
- Arafat Mosab
- Aravkin Aleksandr Y
- Areda Demelash
- Ariffin Hany
- Arifin Hidayat
- Arkew Mesay
- Arooj Mahwish
- Artamonov Anton A
- Artanti Kurnia Dwi
- Aruleba Raphael Taiwo
- Asadi-Pooya Ali A
- Asena Tilahun Ferede
- Asghari-Jafarabadi Mohammad
- Ashraf Muhammad
- Ashraf Tahira
- Atalell Kendalem Asmare
- Athari Seyyed Shamsadin
- Atinafu Bantalem Tilaye Tilaye
- Atorkey Prince
- Atout Maha Moh'd Wahbi
- Atreya Alok
- Aujayeb Avinash
- Avan Abolfazl
- Ayala Quintanilla Beatriz Paulina
- Ayatollahi Haleh
- Ayinde Olatunde O
- Ayyoubzadeh Seyed Mohammad
- Azadnajafabad Sina
- Azizi Zahra
- Azizian Khalil
- Azzam Ahmed Y
- Babaei Mahsa
- Badar Muhammad
- Badiye Ashish D
- Baghdadi Soroush
- Bagherieh Sara
- Bai Ruhai
- Baig Atif Amin
- Balakrishnan Senthilkumar
- Balalla Shivanthi
- Baltatu Ovidiu Constantin
- Banach Maciej
- Bandyopadhyay Soham
- Banerjee Indrajit
- Baran Mehmet Firat
- Barboza Miguel A
- Barchitta Martina
- Bardhan Mainak
- Barker-Collo Suzanne Lyn
- Barrow Amadou
- Bashash Davood
- Bashiri Hamideh
- Bashiru Hameed Akande
- Basiru Afisu
- Basso João Diogo
- Basu Sanjay
- Batiha Abdul-Monim Mohammad
- Batra Kavita
- Baune Bernhard T
- Bedi Neeraj
- Begde Ahmet
- Begum Tahmina
- Behnam Babak
- Behnoush Amir Hossein
- Beiranvand Maryam
- Bekele Alehegn
- Belete Melaku Ashagrie
- Belgaumi Uzma Iqbal
- Bemanalizadeh Maryam
- Bender Rose G
- Benfor Bright
- Bennett Derrick A
- Bensenor Isabela M
- Berice Betyna
- Bettencourt Paulo J G
- Beyene Kebede A
- Bhadra Abhishek
- Bhagat Devidas S
- Bhangdia Kayleigh
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhargava Ashish
- Bhaskar Sonu
- Bhat Ajay Nagesh
- Bhat Vivek
- Bhatti Gurjit Kaur
- Bhatti Jasvinder Singh
- Bhatti Rajbir
- Bijani Ali
- Bikbov Boris
- Bilalaga Mariah Malak
- Biswas Atanu
- Bitaraf Saeid
- Bitra Veera R
- Bjørge Tone
- Bodolica Virginia
- Bodunrin Aadam Olalekan
- Boloor Archith
- Braithwaite Dejana
- Brayne Carol
- Brenner Hermann
- Briko Andrey
- Bringas Vega Maria L
- Brown Julie
- Budke Christine M
- Buonsenso Danilo
- Burkart Katrin
- Burns Richard A
- Bustanji Yasser
- Butt Muhammad Hammad
- Butt Nadeem Shafique
- Butt Zahid A
- Bärnighausen Till Winfried
- Béjot Yannick
- Cabral Lucas Scotta
- Caetano dos Santos Florentino Luciano
- Calina Daniela
- Campos-Nonato Ismael R
- Cao Bochen
- Cao Chao
- Carabin Hélène
- Carreras Giulia
- Carvalho Andre F
- Castañeda-Orjuela Carlos A
- Casulli Adriano
- Catalá-López Ferrán
- Catapano Alberico L
- Cavallera Vanessa
- Caye Arthur
- Cegolon Luca
- Cenderadewi Muthia
- Cerin Ester
- Chacón-Uscamaita Pamela R Uscamaita
- Chan Jeffrey Shi Kai
- Chanie Gashaw Sisay
- Charan Jaykaran
- Chattu Vijay Kumar
- Chekol Abebe Endeshaw
- Chen Hui
- Chen Jianqi
- Chi Gerald
- Chichagi Fatemeh
- Chidambaram Saravana Babu
- Chimoriya Ritesh
- Ching Patrick R
- Chitheer Abdulaal
- Chong Yuen Yu
- Chopra Hitesh
- Choudhari Sonali Gajanan
- Chowdhury Enayet Karim
- Chowdhury Rajiv
- Christensen Hanne
- Chu Dinh-Toi
- Chukwu Isaac Sunday
- Chung Eric
- Coberly Kaleb
- Columbus Alyssa
- Comachio Josielli
- Conde Joao
- Cortesi Paolo Angelo
- Costa Vera Marisa
- Cousin Ewerton
- Couto Rosa A S
- Criqui Michael H
- Cruz-Martins Natália
- Cárdenas Rosario
- D'Amico Emanuele
- Dabbagh Ohadi Mohammad Amin
- Dadana Sriharsha
- Dadras Omid
- Dai Xiaochen
- Dai Zhaoli
- Danawi Hadi A
- Dandona Lalit
- Dandona Rakhi
- Darwish Amira Hamed
- Das Saswati
- Das Subasish
- Dascalu Ana Maria
- Dash Nihar Ranjan
- Dashti Mohsen
- De la Hoz Fernando Pio
- de la Torre-Luque Alejandro
- De Leo Diego
- Dean Frances E
- Dehghan Amin
- Dehghan Azizallah
- Dejene Hiwot
- Demant Daniel
- Demetriades Andreas K
- Demissie Solomon
- Deng Xinlei
- Desai Hardik Dineshbhai
- Devanbu Vinoth Gnana Chellaiyan
- Dhama Kuldeep
- Dharmaratne Samath Dhamminda
- Dhimal Meghnath
- Dias da Silva Diana
- Diaz Daniel
- Dibas Mahmoud
- Ding Delaney D
- Dinu Monica
- Dirac M Ashworth
- Diress Mengistie
- Do Thanh Chi
- Do Thao Huynh Phuong
- Doan Khanh Duy Khanh
- Dodangeh Milad
- Doheim Mohamed Fahmy
- Dokova Klara Georgieva
- Dongarwar Deepa
- Dsouza Haneil Larson
- Dua Tarun
- Dube John
- Duraisamy Senbagam
- Durojaiye Oyewole Christopher
- Dutta Sulagna
- Dziedzic Arkadiusz Marian
- Edinur Hisham Atan
- Eissazade Negin
- Ekholuenetale Michael
- Ekundayo Temitope Cyrus
- El Nahas Nevine
- El Sayed Iman
- Elahi Najafi Mohammad Amin
- Elbarazi Iffat
- Elemam Noha Mousaad
- Elgar Frank J
- Elgendy Islam Y
- Elhabashy Hala Rashad
- Elhadi Muhammed
- Elilo Legesse Tesfaye
- Ellenbogen Richard G
- Elmeligy Omar Abdelsadek Abdou
- Elmonem Mohamed A
- Elshaer Mohammed
- Elsohaby Ibrahim
- Emamverdi Mehdi
- Emeto Theophilus I
- Endres Matthias
- Esezobor Christopher Imokhuede
- Eskandarieh Sharareh
- Fadaei Abdolmajid
- Fagbamigbe Adeniyi Francis
- Fahim Ayesha
- Faramarzi Ali
- Fares Jawad
- Farjoud Kouhanjani Mohsen
- Faro Andre
- Farzadfar Farshad
- Fatehizadeh Ali
- Fathi Mobina
- Fathi Saeid
- Fatima Syeda Anum Fatima
- Feigin Valery L
- Feizkhah Alireza
- Fereshtehnejad Seyed-Mohammad
- Ferrari Alize J
- Ferreira Nuno
- Fetensa Getahun
- Firouraghi Neda
- Fischer Florian
- Fonseca Ana Catarina
- Force Lisa M
- Fornari Arianna
- Foroutan Behzad
- Fukumoto Takeshi
- Gadanya Muktar A
- Gaidhane Abhay Motiramji
- Galali Yaseen
- Galehdar Nasrin
- Gan Quan
- Gandhi Aravind P
- Ganesan Balasankar
- Gardner William M
- Garg Naval
- Gau Shuo-Yan
- Gautam Rupesh K
- Gebre Teshome
- Gebrehiwot Mesfin
- Gebremeskel Gebreamlak Gebremedhn
- Gebreslassie Haftay Gebremedhin
- Getacher Lemma
- Ghaderi Yazdi Bardiya
- Ghadirian Fataneh
- Ghaffarpasand Fariborz
- Ghanbari Reza
- Ghasemi MohammadReza
- Ghazy Ramy Mohamed
- Ghimire Sailaja
- Gholami Ali
- Gholamrezanezhad Ali
- Ghotbi Elena
- Ghozy Sherief
- Gialluisi Alessandro
- Gill Paramjit Singh
- Glasstetter Logan M
- Gnedovskaya Elena V
- Golchin Ali
- Golechha Mahaveer
- Goleij Pouya
- Golinelli Davide
- Gomes-Neto Mansueto
- Goulart Alessandra C
- Goyal Anmol
- Gray Richard J
- Grivna Michal
- Guadie Habtamu Alganeh
- Guan Bin
- Guarducci Giovanni
- Guicciardi Stefano
- Gunawardane Damitha Asanga
- Guo Hanbing
- Gupta Bhawna
- Gupta Rajeev
- Gupta Sapna
- Gupta Veer Bala
- Gupta Vivek Kumar
- Gutiérrez Reyna Alma
- Habibzadeh Farrokh
- Hachinski Vladimir
- Haddadi Rasool
- Hadei Mostafa
- Hadi Najah R
- Haep Nils
- Hagins Hailey
- Haile Teklehaimanot Gereziher
- Haj-Mirzaian Arvin
- Hall Brian J
- Halwani Rabih
- Hameed Sajid
- Hamiduzzaman Mohammad
- Hammoud Ahmad
- Han Hannah
- Hanifi Nasrin
- Hankey Graeme J
- Hannan Md. Abdul
- Hao Junwei
- Harapan Harapan
- Hareru Habtamu Endashaw
- Hargono Arief
- Harlianto Netanja I.
- Haro Josep Maria
- Hartman Nicholas Nathaniel
- Hasaballah Ahmed I.
- Hasan Faizul
- Hasani Hamidreza
- Hasanian Mohammad
- Hassan Amr
- Hassan Shoaib
- Hassanipour Soheil
- Hassankhani Hadi
- Hassen Mohammed Bheser
- Haubold Johannes
- Hay Simon I
- Hayat Khezar
- Hegazy Mohamed I
- Heidari Golnaz
- Heidari Mohammad
- Heidari-Soureshjani Reza
- Hesami Hamed
- Hezam Kamal
- Hiraike Yuta
- Hoffman Howard J
- Holla Ramesh
- Hopf Kathleen Pillsbury
- Horita Nobuyuki
- Hossain Md Mahbub
- Hossain Md. Belal
- Hossain Sahadat
- Hosseinzadeh Hassan
- Hosseinzadeh Mehdi
- Hostiuc Sorin
- Hu Chengxi
- Huang Junjie
- Huda Md. Nazmul
- Hussain Javid
- Hussein Nawfal R
- Huynh Hong-Han
- Hwang Bing-Fang
- Ibitoye Segun Emmanuel
- Ilaghi Mehran
- Ilesanmi Olayinka Stephen
- Ilic Irena M
- Ilic Milena D
- Immurana Mustapha
- Iravanpour Farideh
- Islam Sheikh Mohammed Shariful
- Ismail Faisal
- Iso Hiroyasu
- Isola Gaetano
- Iwagami Masao
- Iwu Chidozie C D
- Iyer Mahalaxmi
- Jaan Ali
- Jacob Louis
- Jadidi-Niaragh Farhad
- Jafari Mahboobeh
- Jafarinia Morteza
- Jafarzadeh Abdollah
- Jahankhani Kasra
- Jahanmehr Nader
- Jahrami Haitham
- Jaiswal Abhishek
- Jakovljevic Mihajlo
- Jamora Roland Dominic G
- Jana Somnath
- Javadi Nilofer
- Javed Saad
- Javeed Saad
- Jayapal Sathish Kumar
- Jayaram Shubha
- Jiang Heng
- Johnson Catherine Owens
- Johnson Walter D
- Jokar Mohammad
- Jonas Jost B
- Joseph Abel
- Joseph Nitin
- Joshua Charity Ehimwenma
- Jürisson Mikk
- Kabir Ali
- Kabir Zubair
- Kabito Gebisa Guyasa
- Kadashetti Vidya
- Kafi Fatemeh
- Kalani Rizwan
- Kalantar Farnaz
- Kaliyadan Feroze
- Kamath Ashwin
- Kamath Sagarika
- Kanchan Tanuj
- Kandel Amit
- Kandel Himal
- Kanmodi Kehinde Kazeem
- Karajizadeh Mehrdad
- Karami Jafar
- Karanth Shama D
- Karaye Ibraheem M
- Karch André
- Karimi Behnagh Arman
- Karimi Aliasghar
- Karimi Hanie
- Kasraei Hengameh
- Kassebaum Nicholas J
- Kauppila Joonas H
- Kaur Harkiran
- Kaur Navjot
- Kayode Gbenga A
- Kazemi Foad
- Keikavoosi-Arani Leila
- Keller Cathleen
- Keykhaei Mohammad
- Khadembashiri Mohammad Amin
- Khader Yousef Saleh
- Khafaie Morteza Abdullatif
- Khajuria Himanshu
- Khalaji Amirmohammad
- Khamesipour Faham
- Khammarnia Mohammad
- Khan Suheb Mahammed Ziauddin
- Khan Maseer
- Khan Moien AB
- Khan Yusra H
- Khanmohammadi Shaghayegh
- Khanna Tripti
- Khatab Khaled
- Khatatbeh Haitham
- Khatatbeh Moawiah Mohammad
- Khateri Sorour
- Khatib Mahalaqua Nazli
- Khayat Kashani Hamid Reza
- Khonji Mohammad Saeid
- khorashadizadeh Fatemeh
- Khormali Moein
- Khubchandani Jagdish
- Kian Saeid
- Kim Grace
- Kim Jihee
- Kim Min Seo
- Kim Yun Jin
- Kimokoti Ruth W
- Kisa Adnan
- Kisa Sezer
- Kivimäki Mika
- Kochhar Sonali
- Kolahi Ali-Asghar
- Koly Kamrun Nahar
- Kompani Farzad
- Koroshetz Walter J
- Kosen Soewarta
- Kourosh Arami Masoumeh
- Koyanagi Ai
- Kravchenko Michael A
- Krishan Kewal
- Krishnamoorthy Vijay
- Kuate Defo Barthelemy
- Kuddus Md Abdul
- Kumar Ashish
- Kumar G Anil
- Kumar Manasi
- Kumar Nithin
- Kumsa Netsanet Bogale
- Kundu Satyajit
- Kurniasari Maria Dyah
- Kusuma Dian
- Kuttikkattu Ambily
- Kyu Hmwe Hmwe
- La Vecchia Carlo
- Ladan Muhammad Awwal
- Lahariya Chandrakant
- Laksono Tri
- Lal Dharmesh Kumar
- Lallukka Tea
- Lami Faris Hasan
- Landires Iván
- Langguth Berthold
- Lasrado Savita
- Latief Kamaluddin
- Latifinaibin Kaveh
- Lau Kathryn Mei-Ming
- Laurens Matthew B
- Lawal Basira Kankia
- Le Long Khanh Dao
- Le Thao Thi Thu
- Ledda Caterina
- Lee Munjae
- Lee Sang-woong
- Lee Seung Won
- Lee Wei-Chen
- Lee Yo Han
- Leonardi Matilde
- Lerango Temesgen L
- Li Ming-Chieh
- Li Wei
- Ligade Virendra S
- Lim Stephen S
- Linehan Christine
- Liu Chaojie
- Liu Jue
- Liu Wei
- Lo Chun-Han
- Lo Warren David
- Lobo Stany W
- Logroscino Giancarlo
- Lopes Graciliana
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- Park Seoyeon
- Parthasarathi Ashwaghosha
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- Rezaei Nazila
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- Saddik Basema
- Sadeghi Erfan
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- Udoakang Aniefiok John
- Ulhaq Inam
- Umair Muhammad
- Umakanthan Srikanth
- Umapathi Krishna Kishore
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- Unnikrishnan Bhaskaran
- Vaithinathan Asokan Govindaraj
- Vakilian Alireza
- Valadan Tahbaz Sahel
- Valizadeh Rohollah
- Van den Eynde Jef
- Vart Priya
- Varthya Shoban Babu
- Vasankari Tommi Juhani
- Vaziri Siavash
- Vellingiri Balachandar
- Venketasubramanian Narayanaswamy
- Verras Georgios-Ioannis
- Vervoort Dominique
- Villafañe Jorge Hugo
- Villani Leonardo
- Vinueza Veloz Andres Fernando
- Viskadourou Maria
- Vladimirov Sergey Konstantinovitch
- Vlassov Vasily
- Volovat Simona Ruxandra
- Vos Theo
- Vu Loc Tri
- Vujcic Isidora S
- Wagaye Birhanu
- Waheed Yasir
- Wahood Waseem
- Walde Mandaras Tariku
- Wang Fang
- Wang Shu
- Wang Yanzhong
- Wang Yuan-Pang
- Waqas Muhammad
- Waris Abdul
- Weerakoon Kosala Gayan
- Weintraub Robert G
- Weldemariam Abrha Hailay
- Westerman Ronny
- Whisnant Joanna L
- Wickramasinghe Dakshitha Praneeth
- Wickramasinghe Nuwan Darshana
- Willekens Barbara
- Wilner Lauren B
- Winkler Andrea Sylvia
- Wolfe Charles D A
- Wu Ai-Min
- Wulf Hanson Sarah
- Xu Suowen
- Xu Xiaoyue
- Yadollahpour Ali
- Yaghoubi Sajad
- Yahya Galal
- Yamagishi Kazumasa
- Yang Lin
- Yano Yuichiro
- Yao Yao
- Yehualashet Sisay Shewasinad
- Yeshaneh Alex
- Yesiltepe Metin
- Yi Siyan
- Yiğit Arzu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- You Yuyi
- Younis Mustafa Z
- Yu Chuanhua
- Yusuf Hadiza
- Zadey Siddhesh
- Zahedi Mohammad
- Zakham Fathiah
- Zaki Nazar
- Zali Alireza
- Zamagni Giulia
- Zand Ramin
- Zandieh Ghazal G Z
- Zangiabadian Moein
- Zarghami Amin
- Zastrozhin Mikhail Sergeevich
- Zeariya Mohammed G M
- Zegeye Zelalem Banjaw
- Zeukeng Francis
- Zhai Chunxia
- Zhang Chen
- Zhang Haijun
- Zhang Yunquan
- Zhang Zhi-Jiang
- Zhao Hanqing
- Zhao Yang
- Zheng Peng
- Zhou Hengxing
- Zhu Bin
- Zhumagaliuly Abzal
- Zielińska Magdalena
- Zikarg Yossef Teshome
- Zoladl Mohammad
- Ärnlöv Johan
- Publication venue
- Elsevier
- Publication date
- 01/04/2024
- Field of study
BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed