33 research outputs found

    Introduction

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    Cysteine-mediated redox signalling in the mitochondria

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    Information Systems Development (ISD) in Complex Settings as Interlocking Spirals of Sense-Making

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    This paper assesses a research framework against the findings of a field research study. The framework employs the metaphor of a triple spiral as a means by which Weick’s sense-making concepts can be applied to ISD activities. The study examines the experiences of members of a large manufacturing organisation in a multinational company. Study participants included project teams members, consultants and senior management. This research is ongoing and other organisations are being engaged in the study. Results suggest that the framework is applicable to the ISD activity and could be used to encourage broad-based research in ISD i.e. research that brings together and understands the relationship between the IS as a social artefact and its complex organisational context. The results support the notion that the framework aids the understanding and management of change at micro- and macro- levels within organisations

    Social Cognition in Adolescent Girls With Fragile X Syndrome

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    This study aimed to characterize social cognition, executive functions (EFs), and everyday social functioning in adolescent girls with fragile X syndrome, and identify relationships among these variables. Participants were 20 girls with FXS and 20 typically developing peers. Results showed significant between-groups differences in social cognition, accounted for by differences in IQ and language. Within the FXS group, IQ and language were related to social cognition; parent-reported social functioning was related to language and EFs; and self-reported social functioning was generally good and not related to cognitive or social cognition variables. Results suggest that intervention might focus on managing language and cognitive contributions to social functioning, rather than social cognition, and underscore the importance of considering parent and adolescent perspectives. (120 words
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