Lower jaw modularity in the African clawed frog (Xenopus laevis) and fire salamander (Salamandra salamandra gigliolii)

Modularity describes the degree to which the components of complex phenotypes vary semi-autonomously due to developmental, genetic and functional correlations. This is a key feature underlying the potential for evolvability, as it can allow individual components to respond to different selective pressures semi-independently. The vertebrate lower jaw has become a model anatomical system for understanding modularity, but to date most of this work has focused on the mandible of mammals and other amniotes. In contrast, modularity in the mandible of lissamphibians has been less well studied. Here, we used geometric morphometrics to quantify the static (intraspecific) modularity patterns in Xenopus laevis and Salamandra salamandra gigliolii. We tested developmental and functional hypotheses of modularity and demonstrate that both species exhibit significant modularity. Functional modularity was supported in both Xenopus and Salamandra. Allometry has a small yet significant impact on lower jaw shape in both taxa and sex has a significant effect on shape in Xenopus. The high lower jaw modularity in both species observed here, combined with the well-established modularity of the amphibian cranium, suggests that modularity is a ubiquitous feature of the tetrapod head

Photographic Assessment of Change in Trichotillomania: Psychometric Properties and Variables Influencing Interpretation

Although photographic assessment has been found to be reliable in assessing hair loss in Trichotillomania, the validity of this method is unclear, particularly for gauging progress in treatment. The current study evaluated the psychometric properties of photographic assessment of change in Trichotillomania. Photographs showing hair loss of adults with Trichotillomania were taken before and after participating in a clinical trial for the condition. Undergraduate college students (N = 211) rated treatment response according to the photos, and additional archival data on hair pulling severity and psychosocial health were retrieved from the clinical trial. Photographic assessment of change was found to possess fair reliability (ICC = 0.53), acceptable criterion validity (r = 0.51), good concurrent validity (r = 0.30–0.36), and excellent incremental validity (ΔR2 = 8.67, p \u3c 0.01). In addition, photographic measures were significantly correlated with change in quality of life (r = 0.42), and thus could be considered an index of the social validity of Trichotillomania treatment. Gender of the photo rater and pulling topography affected the criterion validity of photographic assessment (partial η2 = 0.05–0.11). Recommendations for improving photographic assessment and future directions for hair pulling research are discussed

Controlling, protective, or both: An examination of parenting behaviors associated with child anxiety

Overcontrol and overprotection are often used interchangeably within parenting literature. This has also impacted the questionnaires that are used to assess these parenting behaviors. However, theoretical differences between these constructs may result in different associations with child anxiety. These autonomy-restricting parenting behaviors may be of particular importance during middle childhood/early adolescence as children are building independence during this developmental period. The current study examined measures of overprotective and overcontrolling parenting behaviors in a sample of 262 parents of 8- to- 14-year-old children via online recruitment. Three measures of parenting associated with parental overprotection and overcontrol were examined. Further, a series of factor analyses were completed to examine the factor structures of these measures. An additional factor analysis examined items across all three questionnaires. Individual factors of overcontrol and overprotection that map onto theoretical definitions of the constructs were not found. Findings may indicate that current measures are unable to distinguish between these constructs. Additionally, a measure of overcontrol and a measure of overprotection were both positively associated with child anxiety. There was not a significant difference between the strength of correlations. This research highlights the need for clarity in definitions and measurement of parenting behaviors. Continued research may result in increased utility of parenting measures in the evaluation of child anxiety treatment outcomes

fenics_ice 1.0: A framework for quantifying initialisation uncertainty for time-dependent ice-sheet models

Mass loss due to dynamic changes in ice sheets is a significant contributor to sea level rise, and this contribution is expected to increase in the future. Numerical codes simulating the evolution of ice sheets can potentially quantify this future contribution. However, the uncertainty inherent in these models propagates into projections of sea level rise is and hence crucial to understand. Key variables of ice sheet models, such as basal drag or ice stiffness, are typically initialized using inversion methodologies to ensure that models match present observations. Such inversions often involve tens or hundreds of thousands of parameters, with unknown uncertainties and dependencies. The computationally intensive nature of inversions along with their high number of parameters mean traditional methods such as Monte Carlo are expensive for uncertainty quantification. Here we develop a framework to estimate the posterior uncertainty of inversions and project them onto sea level change projections over the decadal timescale. The framework treats parametric uncertainty as multivariate Gaussian and exploits the equivalence between the Hessian of the model and the inverse covariance of the parameter set. The former is computed efficiently via algorithmic differentiation, and the posterior covariance is propagated in time using a time-dependent model adjoint to produce projection error bars. This work represents an important step in quantifying the internal uncertainty of projections of ice sheet models.</p

Global phylogeography and evolution of chelonid fibropapilloma-associated herpesvirus

A global phylogeny for chelonid fibropapilloma-associated herpesvirus (CFPHV), the most likely aetiological agent of fibropapillomatosis (FP) in sea turtles, was inferred, using dated sequences, through Bayesian Markov chain Monte Carlo analysis and used to estimate the virus evolutionary rate independent of the evolution of the host, and to resolve the phylogenetic positions of new haplotypes from Puerto Rico and the Gulf of Guinea. Four phylogeographical groups were identified: eastern Pacific, western Atlantic/eastern Caribbean, mid-west Pacific and Atlantic. The latter comprises the Gulf of Guinea and Puerto Rico, suggesting recent virus gene flow between these two regions. One virus haplotype from Florida remained elusive, representing either an independent lineage sharing a common ancestor with all other identified virus variants or an Atlantic representative of the lineage giving rise to the eastern Pacific group. The virus evolutionary rate ranged from 1.62x10(-4) to 2.22x10(-4) substitutions per site per year, which is much faster than what is expected for a herpesvirus. The mean time for the most recent common ancestor of the modern virus variants was estimated at 192.90-429.71 years ago, which, although more recent than previous estimates, still supports an interpretation that the global FP pandemic is not the result of a recent acquisition of a virulence mutation(s). The phylogeographical pattern obtained seems partially to reflect sea turtle movements, whereas altered environments appear to be implicated in current FP outbreaks and in the modern evolutionary history of CFPHV.DNER-PR; US NMFS (NMFS-NOAA) [NA08NMF4720436]; US-Fish and Wildlife Service (USFWS); Sociedad Chelonia; WIDECAST; US Environmental Protection Agency (US-EPA); Lisbon Oceanarium, Portugal; Interdisciplinary Research Center for Animal Health of the Faculty of Veterinary Medicine of the Technical University of Lisbon (FMV/TUL)info:eu-repo/semantics/publishedVersio

A multi-resolution analysis of the radio-FIR correlation in the Large Magellanic Cloud

We investigate the local correlation betwen the 1.4 GHz radio continuum and 60 micron far-infrared (FIR) emission within the Large Magellanic Cloud (LMC) on spatial scales between 0.05 and 1.5 kpc. On scales below ~1 kpc, the radio-FIR correlation is clearly better than the correlation of the cold gas tracers with either the radio or the FIR emission. For the LMC as a whole, there is a tight correlation between the radio and FIR emission on spatial scales above ~50 pc. By decomposing the radio emission into thermal and non-thermal components, however, we show that the scale on which the radio-FIR correlation breaks down is inversely proportional to the thermal fraction of the radio emission: regions that show a strong correlation to very small scales are the same regions where the thermal fraction of the radio emission is high. Contrary to previous studies of the local radio-FIR correlation in the LMC, we show that the slope of the relation between the radio and FIR emission is non-linear. In bright star-forming regions, the radio emission increases faster than linearly with respect to the FIR emission (power-law slope of ~1.2), whereas a flatter slope of ~0.6-0.9 applies more generally across the LMC. Our results are consistent with a scenario in which the UV photons and cosmic rays in the LMC have a common origin in massive star formation, but the cosmic rays are able to diffuse away from their production sites. Our results do not provide direct evidence for coupling between the magnetic field and the local gas density, but we note that synchrotron emission may not be a good tracer of the magnetic field if cosmic rays can readily escape the LMC.Comment: 20 pages, accepted MNRAS, full-resolution version available at http://www.atnf.csiro.au/people/twong/preprints/lmcwavlt.pd

Determinants of the income velocity of money in Portugal: 1891–1998

This paper performs a long-run time series analysis of the behaviour of the income velocity of money in Portugal between 1891 and 1998 by assessing the importance of both macroeconomic and institutional factors and looking for particularities in the Portuguese case. We estimate two cointegration vectors for the income velocity of money, macroeconomic variables and institutional variables. It is apparent that one of these vectors reflects the relationship between income velocity and macroeconomic variables, while the other reflects the relationship between income velocity and institutional variables. Moreover, a regression analysis reveals that the usual U-shaped pattern is displayed with a relatively late inflection point located around 1970, which is consistent with the Spanish case. It is further noted that this is a feature of countries with a late economic and institutional development process.info:eu-repo/semantics/publishedVersio

Initial results from the C1XS X-ray spectrometer on Chandrayaan-1

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