Functioning Ovarian Tumours: A Clinical and Pathological Study with Special Reference to the Occurrence of Male-Directed Cells in Granulosa Cell Tumors

(1) A series of 123 ovarian tumours is reported of which 36 were hormonally active. (2) The comparative infertility of women who suffer from ovarian tumours is noted. (3) The prognosis in cases of granulosa cell tumour was found to be good, in cases of carcinoma of the ovary extremely bad. (4) The significance of male directed elements in functioning ovarian tumour is discussed. (3) Evidence is produced that granulosa in tumours should be regarded as a transition between Sertoli and luteal cells. (6) The discarding of such anomalous terms as arrhenoblastoma, androblastoma and gynandroblastoma is recommended as these tumours are shown to be granulosa cell tumours in varying stages of differentiation