Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability

Pseudohypoparathyroidism: A Case Report of a Rare Disease with Uncommon Presentation Producing Diagnostic Dilemma

Pseudohypoparathyroidism (PHP) is a rare hereditary  disorder having the prevalence of 3.4 per million. It is  characterized by symptoms and signs of  hypoparathyroidism, typically in association with distinctive  skeletal and developmental defects. The features of  hypoparathyroidism are due to tissue resistance to the effect  of parathyroid hormone (PTH). We will describe a 32-yearold  woman who had recurrent convulsion for 16 years,  infertility, cataract, psychosis, candidiasis and typical  features of Albright’s hereditary osteodystrophy (AHO),  which include a round face, short neck, short stature and  brachydactyly. Laboratory investigations showed  hypocalcemia, hyperphosphatemia with high PTH level.  Computed tomography scan of head revealed wide spread   calcification in basal ganglia and cerebral hemispheres. X  ray of left foot showed short left 4th metatarsal bone. The  patient was diagnosed as a case of PHP on the basis of  somatic features of AHO with typical biochemical  abnormalities and uncontrolled convulsion with combined  antiepileptic drugs for 16 years. The unusual features in our  case are long delay in clinical diagnosis and absence of family  history. She was treated with calcium salt and vitamin D.  With this treatment patient’s condition was improved and she  experiences no attack of convulsion and carpal spasm.  Anticonvulsants were withdrawn gradually. We recommend  that hypocalcaemia should be excluded before commencing  anticonvulsant therapy in all epileptic patients and those  patients whose seizures are refractory to anticonvulsant drugs   DOI: http://dx.doi.org/10.3329/jbcps.v29i4.11331   J Bangladesh Coll Phys Surg 2011; 29: 227-230</jats:p

Effect of Ipns With Cowdung Bio-Slurry on The Performance of Water Melon in Ganges Tidal Floodplain

The experiment was conducted in medium highland at Dacope, Khulna during rabi season of 2010-11. The aim of the study was to observe the effect of integrated use of bio-slurry along with inorganic fertilizer on the performance of water melon grown in AEZ 13. The experiment was laid out in a randomized complete block design with four replications. Three fertilizer doses viz. T1 : Soil test based inorganic fertilizer dose for high yield goal (HYG), T2 : Cowdung bio-slurry @ 5t/ha + IPNS basis inorganic fertilizer dose for high yield goal and T3 : Farmers’ practice (average of 20 farmers surveyed) were taken as treatment. Results showed that yield and yield contributing characters of water melon were significantly influenced by the treatments. The highest fruit yield (44.50 t/ha) was recorded in cowdung bio-slurry@ 5 t/ha + IPNS basis inorganic fertilizer dose (T2) followed by T1 (40.27 t/ha). The lowest yield (35.20 t/ha) was obtained from farmers’ practice. Economic analysis also revealed that the gross return (Tk. 534000.00/ha) and gross margin (Tk. 427515.00/ha) were higher in T2. Benefit-cost ratio (BCR) was also higher in T2 (5.01).DOI: http://dx.doi.org/10.3329/jesnr.v6i2.22097 J. Environ. Sci. &amp; Natural Resources, 6(2): 61-63 2013</jats:p

Incidence of Endodontic Flare-up in Diabetic and Normal Individual: A 100 case study

Diabetic mellitus is a burning issue in medical ground. If Pulp or periapical pathology develops on diabetic patient, it may need extra attention to manage by root canal treatment. Because very often diabetic patients develop hyperglycemia, leading complex immune response and enhanced virulence of certain microorganism and commonly cause exaggerbration of inter appointment clinical complain like, pain and swelling known as flare-up. The purpose of this study was to clinically examine the development of endodontic flare-up following endodontic intervention in control and in diabetic patient group. In the present study, overall incidence of inter-appointment flare-up in diabetic patients was found to be 19% whereas in non-diabetic group, incidence was 8% that was almost half to the diabetic group. So, this study conclude that root canal treatment can be comfortably done in controlled diabetic patient but need extra care during endodontic treatment if the patient is suffered from uncontrolled diabetes mellitus.&#x0D; Update Dent. Coll. j: 2019; 9 (2): 3-6</jats:p

Responses of barley genotypes for salt tolerance under in vitro culture condition

An experiment was undertaken at Agricultural Botany Laboratory, Patuakhali Science and Technology, to screen out salt tolerant barley (Hordeum vulgare L.) genotypes. The evaluation was done based on germination percentage, shoot length, root length and shoot: root ratio. Five barley genotypes including BARI barley 2, BARI barley 3, BARI barley 4, BARI barley 5 and BARI barley 7 were used in the screening program. The barley genotypes were grown in eight levels NaCl solution like 0(Control), 20, 40, 60, 80, 100 and 120 mM. The present study shows that salinity reduced germination percentage of barley and the extent of reduction increased with the increase in the concentration of salinity in the growth medium. Shoot dry weight (1.40 mg), root dry weight (0.21 mg), shoot moisture content (80.0%), root elongation rate (1.81), vigor index (21.30), speed of germination (7.91) and root length (21.67 cm) were obtained from the variety BARI barley 4 with 80 mMNaCL (V3T4). Based on the growth attributes the genotypes BARI barley 7 and BARI barley 4 were found tolerant to salt stress as they grown up to 60 mM and 80 mMNaCl solution respectively. The genotypes BARI barley 4 was therefore selected to be grown in south coastal saline soil of Bangladesh.&#x0D; Progressive Agriculture 32 (1): 1-9, 2021</jats:p

Investigation of constraints to health and production of cattle in North-East Bangladesh

The study was designed to investigate the constraints to health and productivity of dairy farms and their possible remedies in Sadar Upazila (sub-district) of Sylhet, Sreemangal Upazila at Moulavi Bazar, Chatak and South Sunamgonj Upazila at Sunamgonj districts. Ninety dairy farms including marginal and small (2-10 cows), medium (11-25 cows) and large (&gt;25 cows) of urban, suburban and rural areas were randomly selected for multistage sampling. Farmers were interviewed using pre-tested questionnaire. The major constraints were high price of concentrate, poor knowledge of feeding, scarcity of forage, weak recording system, cost of high yielding well-adapted milking cows, prolonged postpartum anoestrus, repeat breeding, incorrect timing of AI, mastitis, low pregnancy rate, lack of milk co-operative, weak milk marketing and high veterinary cost. To overcome the current situation government should give incentives on cattle feed and credit facility with soft interest to the farmers; DLS and other organizations should arrange effective training on dairy farm management. The Bangladesh Veterinarian (2020) 37(1 - 2): 1-13</jats:p

Compressive Strength of Direct Tooth Colored Restorative Materials

New materials are being introduced to address the need for restoring both carious and non carious (caused by a combination of abrasion, erosion and abfraction) lesions. In an era when more and more patients are retaining their natural dentition, the need for this restoration is increasing. The ideal materials should be adhesive, tooth colored and abrasion-resistant&#x0D; Materials and Methods: Seven disc samples of Compomer, Giomer &amp; Composite restorative materials were prepared for measurement of compressive strength.&#x0D; Results: The value of Compressive strength of Giomer becomes high in comparison to Compomer but not significant in comparison to Composite.&#x0D; Update Dent. Coll. j: 2019; 9 (2): 36-39</jats:p