3,524 research outputs found
Low-damping transmission of spin waves through YIG/Pt-based layered structures for spin-orbit-torque applications
We show that in YIG-Pt bi-layers, which are widely used in experiments on the
spin transfer torque and spin Hall effects, the spin-wave amplitude
significantly decreases in comparison to a single YIG film due to the
excitation of microwave eddy currents in a Pt coat. By introducing a novel
excitation geometry, where the Pt layer faces the ground plane of a microstrip
line structure, we suppressed the excitation of the eddy currents in the Pt
layer and, thus, achieved a large increase in the transmission of the
Damon-Eshbach surface spin wave. At the same time, no visible influence of an
external dc current applied to the Pt layer on the spin-wave amplitude in the
YIG-Pt bi-layer was observed in our experiments with YIG films of micrometer
thickness
Primena molekularnih markera u napretku stoÄarstva
With recent developments in DNA technologies, a large number of genetic polymorphisms at DNA sequence level has been introduced over the last decades as named DNA-based markers. The discovery of new class of DNA profiling markers has facilitated the development of marker-based gene tags, mapbased cloning of livestock important genes, variability studies, phylogenetic analysis, synteny mapping, marker-assisted selection of favourable genotypes, etc. The most commonly used DNA-based markers have advantages over the traditional phenotypic and biochemical markers since they provide data that can be analyzed objectively. In this article the main applications of molecular markers in present-day breeding strategies for livestock improvement - parentage determination, genetic distance estimation, genetic diversity, gene mapping and marker-assisted selection have been reviewed.Sa razvojem DNK tehnologija, veliki broj genetskih polimorfizama na nivou DNK sekvence su predstavljene poseldnjih godina pod nazivom DNK markeri. OtkriÄe novih klasa DNK markera je olakÅ”alo razvoj marker gena, kloniranja gena od važnosti u stoÄarstvu i to na bazi mapa, ispitivanje varijabilnosti, filogenetske analize, mapiranja, selekcije poželjnih genotipova pomoÄu markera, itd. Markeri na bazi DNK koji se najÄeÅ”Äe koriste imaju prednost u odnosu na tradicionalne fenotiske i biohemijske markere jer obezbeÄuju podatke koji se mogu objektivno analizirati. U ovom radu su predstavljeni naÄini koriÅ”Äenja i aplikacija molekularnih markera u postojeÄim odgajivaÄkim strategijama odn. napretku stoÄarstva - odreÄivanje porekla, ocena genetske distance, genetskog diverziteta, mapiranje gena i selekcija pomoÄu markera
Security and confidentiality approach for the Clinical E-Science Framework (CLEF)
Objectives: CLEF is an MRC sponsored project in the E-Science programme that aims to establish methodologies and a technical infrastructure for the next generation of integrated clinical and bioscience research. Methods: The heart of the CLEF approach to this challenge is to design and develop a pseudonymised repository of histories of cancer patients that can be accessed by researchers. Robust mechanisms and policies have been developed to ensure that patient privacy and confidentiality are preserved while delivering a repository of such medically rich information for the purposes of scientific research. Results: This paper summarises the overall approach adopted by CLEF to meet data protection requirements, including the data flows, pseudonymisation measures and additional monitoring policies that are currently being developed. Conclusion: Once evaluated, it is hoped that the CLEF approach can serve as a model for other distributed electronic health record repositories to be accessed for research
Security and confidentiality approach for the Clinical E-Science Framework (CLEF)
CLEF is an MRC sponsored project in the E-Science programme that aims to
establish policies and infrastructure for the next generation of integrated clinical and
bioscience research. One of the major goals of the project is to provide a
pseudonymised repository of histories of cancer patients that can be accessed by
researchers. Robust mechanisms and policies are needed to ensure that patient
privacy and confidentiality are preserved while delivering a repository of such
medically rich information for the purposes of scientific research. This paper
summarises the overall approach adopted by CLEF to meet data protection
requirements, including the data flows and pseudonymisation mechanisms that are
currently being developed. Intended constraints and monitoring policies that will
apply to research interrogation of the repository are also outlined. Once evaluated, it
is hoped that the CLEF approach can serve as a model for other distributed
electronic health record repositories to be accessed for research
Joining up health and bioinformatics: e-science meets e-health
CLEF (Co-operative Clinical e-Science Framework) is an MRC sponsored project in the e-Science programme that aims to establish methodologies and a technical infrastructure forthe next generation of integrated clinical and bioscience research. It is developing methodsfor managing and using pseudonymised repositories of the long-term patient histories whichcan be linked to genetic, genomic information or used to support patient care. CLEF concentrateson removing key barriers to managing such repositories ? ethical issues, informationcapture, integration of disparate sources into coherent ?chronicles? of events, userorientedmechanisms for querying and displaying the information, and compiling the requiredknowledge resources. This paper describes the overall information flow and technicalapproach designed to meet these aims within a Grid framework
The statistical properties of the city transport in Cuernavaca (Mexico) and Random matrix ensembles
We analyze statistical properties of the city bus transport in Cuernavaca
(Mexico) and show that the bus arrivals display probability distributions
conforming those given by the Unitary Ensemble of random matrices.Comment: 4 pages, 3 figure
Nanofabricated tips for device-based scanning tunneling microscopy
We report on the fabrication and performance of a new kind of tip for
scanning tunneling microscopy. By fully incorporating a metallic tip on a
silicon chip using modern micromachining and nanofabrication techniques, we
realize so-called smart tips and show the possibility of device-based STM tips.
Contrary to conventional etched metal wire tips, these can be integrated into
lithographically defined electrical circuits. We describe a new fabrication
method to create a defined apex on a silicon chip and experimentally
demonstrate the high performance of the smart tips, both in stability and
resolution. In situ tip preparation methods are possible and we verify that
they can resolve the herringbone reconstruction and Friedel oscillations on
Au(111) surfaces. We further present an overview of possible applications
Computing generalized inverses using LU factorization of matrix product
An algorithm for computing {2, 3}, {2, 4}, {1, 2, 3}, {1, 2, 4} -inverses and
the Moore-Penrose inverse of a given rational matrix A is established. Classes
A(2, 3)s and A(2, 4)s are characterized in terms of matrix products (R*A)+R*
and T*(AT*)+, where R and T are rational matrices with appropriate dimensions
and corresponding rank. The proposed algorithm is based on these general
representations and the Cholesky factorization of symmetric positive matrices.
The algorithm is implemented in programming languages MATHEMATICA and DELPHI,
and illustrated via examples. Numerical results of the algorithm, corresponding
to the Moore-Penrose inverse, are compared with corresponding results obtained
by several known methods for computing the Moore-Penrose inverse
Investigation of gene pool and genealogical links between sheep breeds of southern Russia by blood groups and DNA microsatellites
To study the gene pool and the establishment of genealogical relationships between breeds of sheep of different directions productivity bred in Russia, were used two classes of genetic markers - blood and DNA microsatellites. The included sample sheep are fine-wool Merino breeds: Grozny (GR), Caucasian (CA), Manychskij merino (MM), the Soviet Merino (SM), Stavropol (ST) and coarse wool breeds: Edilbaevskaya (ED), Karakul (CR) and Romanov (RO). For the study of erythrocyte, were selected antigens (blood group) in 1159 samples from 11 breeding farms. For microsatellite DNA study - 598 from 10 breeding farms. Microsatellite analysis revealed that the most polymorphic were Stavropol breed sheep that have identified an average of 18.27 alleles per locus were relatively conservative Romanov breed sheep - 9.7 alleles per locus. The minimum genetic distances established between Grozny and Soviet Merino - 0.0569 (for microsatellites) and 0.0741 (blood groups - later in the same sequence). The rocks of the Stavropol - Grozny were 0.0861 and 0, 0810. Whereas Stavropol and Soviet Merino 0.0861 and 0.1094. Also relatively close between Grozny - Edilbaevskoy, Grozny Karakul, Edilbaevskoy - Karakul: 0.1364 and 0.0851, respectively; 0.1620 and 0.1208; 0.1875 and 0.1192. The highest genetic distances were between Stavropol and Karakul 0.2664 and 0.1804, as well as between the Romanov and all studied species - 0.2491 ... 0.3211 and 0.1734 ... 0.2235
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