Optimising the value of the evidence generated in Implementation Science : the use of ontologies to address the challenges

Our thanks to Marta Marques, Emma Norris, Ildiko Tombor, Holly Walton, Olga Perski and Hilary Groarke for comments on an earlier draft of this editorial. The project is funded by a Wellcome Trust collaborative award [The Human Behaviour-Change Project: Building the science of behaviour change for complex intervention development’, 201,524/Z/16/Z].Peer reviewedPublisher PD

Changing clinical behaviour by making guidelines specific

Efforts to get doctors to follow guidelines have overlooked the importance of clear and concise recommendation

Taking stock of structural funds implementation : current challenges and future opportunities

This paper highlights several themes which have informed programme management since IQ-Net meeting in June 2002, held in Lulea, Sweden. First, it provides an overview of the main development in programme implementation and the financial execution of programmes, including an exploration of the risks of automatic decommitment faced by the programmes. Second, it describes the progress made with the mid-term evaluations, following on the IQ-Net thematic paper on this subject presented at the Lulea conference. Third, it presents an overview of the current EU-level debate on simplification, highlighting the views of the network's partners as well as, where available, the member state

Increasing transmission efficiency with advanced signal processing

Optical CDMA is an advanced and flexible communication technology with a potential to offer very energy efficient and highly scalable networking. In addition it can also deliver increased physical layer privacy and on-demand bandwidth sharing management. We have developed, extensively investigated, and experimentally demonstrated highly scalable approach to incoherent OCDMA which can very efficiently increase the number of simultaneous users. In addition, the introduction of an advanced photonic signal processing results in an overall system power budget improvement by nearly 3dB. Error-free operation with the BER less than 10-12 was achieved. We have also shown that with demonstrated approach we can dramatically improve number of simultaneous network users (up to ten times) while keeping the related hardware count unchanged. By comparing this results to DWDM concept, this substantial increase in number of simultaneous users did not require to add any additional wavelength laser sources and was achieved by employing just three communication wavelengths

High Energy Gamma-rays from Globular Clusters

It is expected that specific globular clusters can contain up to a hundred of millisecond pulsars. These pulsars can accelerate leptons at the shock waves originated in collisions of the pulsar winds and/or inside the pulsar magnetospheres. Energetic leptons diffuse gradually through the globular cluster comptonizing stellar and microwave background radiation. We calculate the GeV-TeV $\gamma$-ray spectra for different models of injection of leptons and parameters of the globular clusters assuming reasonable, of the order of 1%, efficiency of energy conversion from the pulsar winds into the relativistic leptons. It is concluded that leptons accelerated in the globular cluster cores should produce well localized $\gamma$-ray sources which are concentric with these globular clusters. The results are shown for four specific globular clusters (47 Tuc, Ter 5, M13, and M15), in which significant population of millisecond pulsars have been already discovered. We argue that the best candidates, which might be potentially detected by the present Cherenkov telescopes and the planned satellite telescopes (AGILE, GLAST), are 47 Tuc on the southern hemisphere, and M13 on the northern hemisphere. We conclude that detection (or non-detection) of GeV-TeV $\gamma$-ray emission from GCs by these instruments put important constraints on the models of acceleration of leptons by millisecond pulsars.Comment: 12 pages, 10 figures, 1 table, accepted to MNRA