17 research outputs found
COVID-19 Severity and Survival over Time in Patients with Hematologic Malignancies: A Population-Based Registry Study
- Author
- Alegre Amor Adrián
- Alonso Arancha
- Aláez Usón María Concepción
- Arroyo Barea Andrés
- Bastos Oreiro Mariana Beatriz
- Benavente Cuesta Celina
- Bustelos Rodriguez Rosalía
- Calbacho Robles Maria
- Callejas Charavia Marta
- Canales Albendea Miguel Ángel
- Casas Rojo Jose Manuel
- Cedillo Ángel
- De la Cruz Javier
- Del Campo Juan Francisco
- Diez Martín José Luis
- Duarte Rafael
- Escolano Escobar Cristian
- Estival Monteliu Pablo
- Fuente Adolfo de la
- García Roa María
- García Suárez Julio
- Gil Manso Rodrigo
- González Gascón y Marín Isabel
- González Santillana Clara
- Grande Carlos
- Hernández Rivas José Ángel
- Herrera Puente Pilar
- Herráez Regina
- Jacome Yerovi Cristina
- Jiménez Yuste Víctor
- Kwon Mi
- Llamas Pilar
- Lumbreras Bermejo Carlos Juan
- López Jiménez Javier
- Marcheco-Pupo Eriel Alexis
- Martos Martinez Rafael
- Martínez Barranco Pilar
- Martínez Chamorro Carmen
- Martínez Díez Yolanda
- Martínez López Joaquín
- Matilla García Arturo
- Núñez Martín Buitrago Lucía
- Ortiz Javier
- Pascual Adriana
- Pérez Oteyza Jaime
- Quiroz Cervantes Keina
- Rosado Sierra Belén
- Ruiz Mediavilla Elena
- Sebrango Ana
- Sánchez Godoy Pedro
- Valenciano Susana
- Publication venue
- MDPI
- Publication date
- 01/01/2023
- Field of study
Mortality rates for COVID-19 have declined over time in the general population, but data in patients with hematologic malignancies are contradictory. We identified independent prognostic factors for COVID-19 severity and survival in unvaccinated patients with hematologic malignancies, compared mortality rates over time and versus non-cancer inpatients, and investigated post COVID-19 condition. Data were analyzed from 1166 consecutive, eligible patients with hematologic malignancies from the population-based HEMATO-MADRID registry, Spain, with COVID-19 prior to vaccination roll-out, stratified into early (February–June 2020; n = 769 (66%)) and later (July 2020–February 2021; n = 397 (34%)) cohorts. Propensity-score matched non-cancer patients were identified from the SEMI-COVID registry. A lower proportion of patients were hospitalized in the later waves (54.2%) compared to the earlier (88.6%), OR 0.15, 95%CI 0.11–0.20. The proportion of hospitalized patients admitted to the ICU was higher in the later cohort (103/215, 47.9%) compared with the early cohort (170/681, 25.0%, 2.77; 2.01–3.82). The reduced 30-day mortality between early and later cohorts of non-cancer inpatients (29.6% vs. 12.6%, OR 0.34; 0.22–0.53) was not paralleled in inpatients with hematologic malignancies (32.3% vs. 34.8%, OR 1.12; 0.81–1.5). Among evaluable patients, 27.3% had post COVID-19 condition. These findings will help inform evidence-based preventive and therapeutic strategies for patients with hematologic malignancies and COVID-19 diagnosis.Depto. de MedicinaFac. de MedicinaTRUEFundación Madrileña de Hematología y HemoterapiaFundación Leucemia y LinfomaAsociación Madrileña de Hematología y Hemoterapiapu
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
- Author
- Abdellaoui Abdel
- Abramova Liliya
- Adams Mark
- Adams Mark J.
- Adan Roger A. H.
- Adolfsson Rolf
- Adolfsson Rolf
- Adorjan Kristina
- Agartz Ingrid
- Agartz Ingrid
- Agerbo Esben
- Agerbo Esben
- Agerbo Esben
- Aguayo Samuel
- Ahuja Sunil
- Air Tracy M.
- Air Tracy M.
- Al Eissa Mariam
- Albani Diego
- Alda Martin
- Alda Martin
- Alfredsson Lars
- Alfredsson Lars
- Alfredsson Lars
- Alliey-Rodriguez Ney
- Als Thomas D.
- Andlauer Till F. M.
- Ando Tetsuya
- Andreassen Ole A.
- Andreassen Ole A.
- Andreassen Ole A.
- Anjorin Adebayo
- Anjorin Adebayo
- Antilla Verneri
- Antoniou Anastasia
- Appadurai Vivek
- Argyres Dean P.
- Arolt Volker
- Artigas Maria Soler
- Aschauer Harald
- Ashley-Koch Allison E.
- Aslan Mihaela
- Awasthi Swapnil
- Awasthi Swapnil
- Awasthi Swapnil
- Azevedo M. Helena
- Babadjanova Gulja
- Bacanu Silviu-Alin
- Backlund Lena
- Baek Ji Hyun
- Baker Jessica H.
- Ballas Zuhair
- Bass Nicholas
- Bass Nicholas
- Bau Claiton H. D.
- Bauer Michael
- Baune Bernhard T.
- Baune Bernhard T.
- Baune Bernhard T.
- Beckham Jean
- Beckham Jean
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- Bellivier Frank
- Bellivier Frank
- Bencko Vladimir
- Bengesser Susanne
- Bergen Andrew W.
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- Berger Klaus
- Berrettini Wade H.
- Berrettini Wade H.
- Berrettini Wade H.
- Bhushan Sujata
- Biernacka Joanna M.
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- Bigdeli Tim B.
- Bigdeli Tim B.
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- Brum Murielle
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- Cahn Wiepke
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- Cichon Sven
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- Clementi Maurizio
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- Coleman Jonathan R. I.
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- Connor Todd
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- Senner Fanny
- Serretti Alessandro
- Serretti Alessandro
- Servatius Richard
- Shabalin Andrey
- Shannon Weickert Cynthia
- Sharma Satish
- Sharp Sally
- Shayan Shahpoor
- Shen Ling
- Sherman Scott
- Shi Jianxin
- Shi Jianxin
- Shilling Paul D.
- Shyn Stanley I.
- Shyn Stanley I.
- Sigurdsson Engilbert
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- Sinnamon Grant C. B.
- Sirignano Lea
- Sirignano Lea
- Sklar Pamela
- Slachtova Lenka
- Slagboom P. Eline
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- Slof-Op ‘t Landt Margarita C. T.
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- Sorbi Sandro
- Southam Lorraine
- Spalletta Gianfranco
- Spijker Anne T.
- Sriram Peruvemba
- Stahl Eli A.
- Stahl Eli A.
- Stapley Todd
- Starnawska Anna
- Steen Vidar W.
- Stefansson Hreinn
- Stefansson Hreinn
- Stefansson Kari
- Stefansson Kari
- Stein Dan J.
- Stein Murray B.
- Steinberg Stacy
- Steinberg Stacy
- Stephens Brady
- Stordal Eystein
- Strauss John S.
- Strauss John S.
- Streit Fabian
- Streit Fabian
- Streit Fabian
- Streit Fabian
- Striker Robert
- Strober Michael
- Strober Michael
- Strohmaier Jana
- Strollo Patrick
- Stuber Garret D.
- Su Mei-Hsin
- Sullivan Patrick F.
- Sullivan Patrick F.
- Sullivan Patrick F.
- Sun Yan
- Szatkiewicz Jin P.
- Sánchez-Mora Cristina
- Sánchez-Mora Cristina
- Tachmazidou Ioanna
- Tandon Neeraj
- Tansey Katherine E.
- Teismann Henning
- Tenconi Elena
- Terao Chikashi
- Teumer Alexander
- Thompson Wesley
- Thomson Pippa A.
- Thorgeirsson Thorgeir E.
- Thorgeirsson Thorgeir E.
- Thornton Laura M.
- Thornton Laura M.
- Tiemeier Henning
- Toma Claudio
- Tooney Paul
- Tortorella Alfonso
- Tozzi Federica
- Traylor Matthew
- Treasure Janet
- Treasure Janet
- Treutlein Jens
- Treutlein Jens
- Trubetskoy Vassily
- Trubetskoy Vassily
- Trzaskowski Maciej
- Trzaskowski Maciej
- Tsao Philip
- Tsao Philip S.
- Tsao Philip S.
- Tsao Philip S.
- Tsermpini Evangelia-Eirini
- Tsitsika Artemis
- Tsuang Ming T.
- Turecki Gustavo
- Turecki Gustavo
- Tyszkiewicz-Nwafor Marta
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- Vedder Helmut
- Vieta Eduard
- Viktorin Alexander
- Vilar-Ribó Laura
- Villareal Gerardo
- Vincent John B.
- Vincent John B.
- Visscher Peter M.
- Völzke Henry
- Völzke Henry
- Wade Tracey D.
- Wagner Gudrun
- Waldman Irwin D.
- Wallbom Agnes
- Walters James T. R.
- Walters James T. R.
- Walton Esther
- Wang Yunpeng
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- Wasserman Danuta
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- Watson Hunna J.
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- Weickert Cynthia Shannon
- Weickert Thomas W.
- Weickert Thomas W.
- Weinsheimer Shantel Marie
- Weissman Myrna M.
- Weissman Myrna M.
- Wellmann Jürgen
- Werge Thomas
- Werge Thomas
- Werge Thomas
- Werge Thomas
- Whitbourne Stacey B.
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- Whiteman David C.
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- Whooley Mary
- Wichmann H. Erich
- Widen Elisabeth
- Willemsen Gonneke
- Williams Leanne M.
- Willour Virginia
- Wilson Peter
- Winsvold Bendik S.
- Witt Stephanie H.
- Witt Stephanie H.
- Witt Stephanie H.
- Witt Stephanie H.
- Won Hong-Hee
- Woodside D. Blake
- Woodside D. Blake
- Wray Naomi R.
- Wray Naomi R.
- Wray Naomi R.
- Wu Yang
- Xi Hualin S.
- Xi Simon
- Xu Junzhe
- Xu Wei
- Yang Jian
- Yao Shuyang
- Yeh Shing Shing
- Yilmaz Zeynep
- Yilmaz Zeynep
- Young Allan H.
- Young Hannah
- Zablocki Clement J.
- Zai Clement C.
- Zandi Peter P.
- Zeggini Eleftheria
- Zerwas Stephanie
- Zhang Futao
- Zhao Hongyu
- Zhou Hang
- Zillich Lea
- Zillich Lea
- Zipfel Stephan
- Zwart John-Anker
- Świątkowska Beata
- Świątkowska Beata
- Świątkowska Beata
- Publication venue
- Publication date
- 01/01/2021
- Field of study
Background Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. Methods We conducted a genome-wide association study (GWAS) of 29,782 suicide attempt (SA) cases and 519,961 controls in the International Suicide Genetics Consortium (ISGC). The GWAS of SA was conditioned on psychiatric disorders using GWAS summary statistics via multitrait-based conditional and joint analysis, to remove genetic effects on SA mediated by psychiatric disorders. We investigated the shared and divergent genetic architectures of SA, psychiatric disorders, and other known risk factors. Results Two loci reached genome-wide significance for SA: the major histocompatibility complex and an intergenic locus on chromosome 7, the latter of which remained associated with SA after conditioning on psychiatric disorders and replicated in an independent cohort from the Million Veteran Program. This locus has been implicated in risk-taking behavior, smoking, and insomnia. SA showed strong genetic correlation with psychiatric disorders, particularly major depression, and also with smoking, pain, risk-taking behavior, sleep disturbances, lower educational attainment, reproductive traits, lower socioeconomic status, and poorer general health. After conditioning on psychiatric disorders, the genetic correlations between SA and psychiatric disorders decreased, whereas those with nonpsychiatric traits remained largely unchanged. Conclusions Our results identify a risk locus that contributes more strongly to SA than other phenotypes and suggest a shared underlying biology between SA and known risk factors that is not mediated by psychiatric disorders.Peer reviewe
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
- Author
- Abarca-Gómez Leandra
- Abdeen Ziad A
- Abdrakhmanova Shynar
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Mohamad Hasnan
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmed Soheir H
- Ahrens Wolfgang
- Aitmurzaeva Gulmira
- Ajlouni Kamel
- Al Nsour Mohannad
- Al-Hazzaa Hazzaa M
- Al-Lahou Badreya
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Alvarez-Pedrerol Mar
- Aly Eman
- Amarapurkar Deepak N
- Amiri Parisa
- Amougou Norbert
- Amouyel Philippe
- Anderssen Sigmund A
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Aounallah-Skhiri Hajer
- Araújo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assunção Maria Cecília F
- Aung May Soe
- Auvinen Juha
- Avdicová Mária
- Avi Shina
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Baharudin Azli
- Bahijri Suhad
- Baker Jennifer L
- Balakrishna Nagalla
- Bamoshmoosh Mohamed
- Banach Maciej
- Bandosz Piotr
- Banegas José R
- Bao Tran Quoc
- Baran Joanna
- Barbagallo Carlo M
- Barceló Alberto
- Barkat Amina
- Barros Aluisio JD
- Barros Mauro Virgílio Gomes
- Basit Abdul
- Bastos Joao Luiz D
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- Batista Rosangela L
- Battakova Zhamilya
- Batyrbek Assembekov
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- Beaglehole Robert
- Bebakar Wan Mohamad Wan
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- Benchekor Sounnia Mediene
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- Benet Mikhail
- Bennett James E
- Bergh Ingunn Holden
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
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- Bezerra Jorge
- Bhagyalaxmi Aroor
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- Braeckman Lutgart
- Bragt Marjolijn CE
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- Döring Angela
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- Egbagbe Eruke E
- Eggertsen Robert
- Eghtesad Sareh
- Ei K Nang Ei
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- Ekelund Ulf
- El Ati Jalila
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- Ferrer Eldridge
- Ferrieres Jean
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- Gafencu Mihai
- Galbarczyk Andrzej
- Galenkamp Henrike
- Galeone Daniela
- Galfo Myriam
- Galvano Fabio
- Gao Jingli
- Garba Jamila Abubakar
- Garcia-de-la-Hera Manoli
- García-Solano Marta
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- Gottrand Frederic
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- Regecová Valéria
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- Rojas-Martinez Rosalba
- Rojroongwasinkul Nipa
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- Rosario Angelika Schaffrath
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- Rosengren Annika
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- Ruidavets Jean-Bernard
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- Varela-Moreiras Gregorio
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- Veronesi Giovanni
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- Vineis Paolo
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- Viswanathan Bharathi
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- Vollenweider Peter
- Voutilainen Ari
- Voutilainen Sari
- Vrijheid Martine
- Vrijkotte Tanja GM
- Vrkic Tajana Zeljkovic
- Völzke Henry
- Wade Alisha N
- Wagner Aline
- Waldhör Thomas
- Walton Janette
- Wambiya Elvis OA
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
- Wannamethee S Goya
- Wareham Nicholas
- Weber Adelheid
- Wedderkopp Niels
- Weerasekera Deepa
- Weghuber Daniel
- Wei Wenbin
- Weres Aneta
- Werner Bo
- Whincup Peter H
- Widhalm Kurt
- Widyahening Indah S
- Wiecek Andrzej
- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Julianne
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Jyh Eiin
- Wong Norazizah Ibrahim
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Jianfeng
- Wu Li Juan
- Wu Shouling
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yamborisut Uruwan
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yardim Nazan
- Yaseri Mehdi
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You Qi Sheng
- You San-Lin
- Younger-Coleman Novie O
- Yusoff Ahmad Faudzi
- Yusoff Muhammad Fadhli Mohd
- Zaccagni Luciana
- Zafiropulos Vassilis
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zamrazilová Hana
- Zapata Maria Elisa
- Zargar Abdul Hamid
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhao Wenhua
- Zhen Shiqi
- Zheng Wei
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhou Maigeng
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zuziak Monika
- Ängquist Lars
- Łuszczki Edyta
- Ševcíková Ludmila
- Publication venue
- eLife Sciences Publications
- Publication date
- 01/01/2021
- Field of study
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants
- Author
- Abarca-Gómez Leandra
- Abdeen Ziad A
- Abdul Rahim Hanan F
- Abu-Rmeileh Niveen M
- Acosta-Cazares Benjamin
- Adams Robert J
- Aekplakorn Wichai
- Afsana Kaosar
- Afzal Shoaib
- Agdeppa Imelda A
- Aghazadeh-Attari Javad
- Aguilar-Salinas Carlos A
- Agyemang Charles
- Ahmad Noor Ani
- Ahmadi Ali
- Ahmadi Naser
- Ahmadi Nastaran
- Ahmadizar Fariba
- Ahmed Soheir H
- Ahrens Wolfgang
- Ajlouni Kamel
- Al-Raddadi Rajaa
- Alarouj Monira
- AlBuhairan Fadia
- AlDhukair Shahla
- Ali Mohamed M
- Alkandari Abdullah
- Alkerwi Ala'a
- Allin Kristine
- Aly Eman
- Amarapurkar Deepak N
- Amougou Norbert
- Amouyel Philippe
- Andersen Lars Bo
- Anderssen Sigmund A
- Anjana Ranjit Mohan
- Ansari-Moghaddam Alireza
- Ansong Daniel
- Aounallah-Skhiri Hajer
- Araújo Joana
- Ariansen Inger
- Aris Tahir
- Arku Raphael E
- Arlappa Nimmathota
- Aryal Krishna K
- Aspelund Thor
- Assah Felix K
- Assunção Maria Cecília F
- Auvinen Juha
- Avdićová Mária
- Azevedo Ana
- Azimi-Nezhad Mohsen
- Azizi Fereidoun
- Azmin Mehrdad
- Babu Bontha V
- Bahijri Suhad
- Balakrishna Nagalla
- Balanova Yulia
- Bamoshmoosh Mohamed
- Banach Maciej
- Banadinović Maja
- Bandosz Piotr
- Banegas José R
- Baran Joanna
- Barbagallo Carlo M
- Barceló Alberto
- Barkat Amina
- Barreto Marta
- Barros Aluisio JD
- Barros Mauro Virgílio Gomes
- Bartosiewicz Anna
- Basit Abdul
- Bastos Joao Luiz D
- Bata Iqbal
- Batieha Anwar M
- Batyrbek Assembekov
- Baur Louise A
- Beaglehole Robert
- Belavendra Antonisamy
- Ben Romdhane Habiba
- Benet Mikhail
- Bennett James E
- Benson Lowell S
- Berkinbayev Salim
- Bernabe-Ortiz Antonio
- Bernotiene Gailute
- Bettiol Heloísa
- Bezerra Jorge
- Bhagyalaxmi Aroor
- Bhargava Santosh K
- Bia Daniel
- Biasch Katia
- Bika Lele Elysée Claude
- Bikbov Mukharram M
- Bista Bihungum
- Bjerregaard Peter
- Bjertness Espen
- Bjertness Marius B
- Björkelund Cecilia
- Bloch Katia V
- Blokstra Anneke
- Bo Simona
- Bobak Martin
- Boeing Heiner
- Boggia Jose G
- Boissonnet Carlos P
- Bojesen Stig E
- Bongard Vanina
- Bonilla-Vargas Alice
- Bopp Matthias
- Borghs Herman
- Bovet Pascal
- Boyer Christopher B
- Braeckman Lutgart
- Brajkovich Imperia
- Branca Francesco
- Breckenkamp Juergen
- Brenner Hermann
- Brewster Lizzy M
- Briceño Yajaira
- Brito Miguel
- Bruno Graziella
- Bueno Gloria
- Bueno-de-Mesquita H Bas
- Bugge Anna
- Burns Con
- Bursztyn Michael
- Cabrera de León Antonio
- Cacciottolo Joseph
- Cameron Christine
- Can Günay
- Capanzana Mario V
- Capuano Eduardo
- Capuano Vincenzo
- Cardoso Viviane C
- Carlsson Axel C
- Carrillo-Larco Rodrigo M
- Carvalho Joana
- Casanueva Felipe F
- Censi Laura
- Cervantes-Loaiza Marvin
- Chadjigeorgiou Charalambos A
- Chamukuttan Snehalatha
- Chan Angelique W
- Chan Queenie
- Chaturvedi Himanshu K
- Chaturvedi Nish
- Chee Miao Li
- Chen Chien-Jen
- Chen Fangfang
- Chen Huashuai
- Chen Shuohua
- Chen Zhengming
- Cheng Ching-Yu
- Cheraghian Bahman
- Cherkaoui Dekkaki Imane
- Chetrit Angela
- Chien Kuo-Liong
- Chiolero Arnaud
- Chiou Shu-Ti
- Chirita-Emandi Adela
- Chirlaque María-Dolores
- Cho Belong
- Christensen Kaare
- Christofaro Diego G
- Chudek Jerzy
- Cifkova Renata
- Cinteza Eliza
- Claessens Frank
- Clarke Janine
- Clays Els
- Cohen Emmanuel
- Concin Hans
- Cooper Cyrus
- Coppinger Tara C
- Costanzo Simona
- Cottel Dominique
- Cowan Melanie J
- Cowell Chris
- Craig Cora L
- Crampin Amelia C
- Crujeiras Ana B
- Cruz Juan J
- Csilla Semánová
- Cui Liufu
- Cureau Felipe V
- Cuschieri Sarah
- Cândido Ana Paula C
- D'Arrigo Graziella
- d'Orsi Eleonora
- Dallongeville Jean
- Damasceno Albertino
- Danaei Goodarz
- Dankner Rachel
- Dantoft Thomas M
- Dauchet Luc
- Davletov Kairat
- De Backer Guy
- De Bacquer Dirk
- De Curtis Amalia
- de Gaetano Giovanni
- De Henauw Stefaan
- de Oliveira Paula Duarte
- De Ridder David
- De Smedt Delphine
- Deepa Mohan
- Deev Alexander D
- DeGennaro Vincent Jr
- Delisle Hélène
- Demarest Stefaan
- Dennison Elaine
- Deschamps Valérie
- Dhimal Meghnath
- Di Castelnuovo Augusto F
- Dias-da-Costa Juvenal Soares
- Diaz Alejandro
- Dickerson Ty T
- Dika Zivka
- Djalalinia Shirin
- Do Ha TP
- Dobson Annette J
- Donfrancesco Chiara
- Donoso Silvana P
- Dorobantu Maria
- Doua Kouamelan
- Dragano Nico
- Drygas Wojciech
- Duante Charmaine A
- Duboz Priscilla
- Duda Rosemary B
- Dulskiene Virginija
- Dushpanova Anar
- Dzerve Vilnis
- Dziankowska-Zaborszczyk Elzbieta
- Döring Angela
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- Džakula Aleksandar
- Eddie Ricky
- Eftekhar Ebrahim
- Eggertsen Robert
- Eghtesad Sareh
- Eiben Gabriele
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- Panza Francesco
- Paoli Mariela
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- Piwonska Aleksandra
- Pizarro Andreia n
- Plans-Rubió Pedro
- Polašek Ozren
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- Wambiya Elvis OA
- Wan Bebakar Wan Mohamad
- Wan Mohamud Wan Nazaimoon
- Wanderley Júnior Rildo de Souza
- Wang Ming-Dong
- Wang Ningli
- Wang Qian
- Wang Xiangjun
- Wang Ya Xing
- Wang Ying-Wei
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- Wareham Nicholas
- Wei Wenbin
- Weres Aneta
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- Whincup Peter H
- Widhalm Kurt
- Widyahening Indah S
- Wiecek Andrzej
- Wilks Rainford J
- Willeit Johann
- Willeit Peter
- Williams Emmanuel A
- Wilsgaard Tom
- Wojtyniak Bogdan
- Wong Andrew
- Wong Tien Yin
- Wong-McClure Roy A
- Woo Jean
- Woodward Mark
- Wu Frederick C
- Wu Shouling
- Wyszynska Justyna
- Xu Haiquan
- Xu Liang
- Yaacob Nor Azwany
- Yan Weili
- Yang Ling
- Yang Xiaoguang
- Yang Yang
- Yasuharu Tabara
- Ye Xingwang
- Yiallouros Panayiotis K
- Yoosefi Moein
- Yoshihara Akihiro
- You San-Lin
- Younger-Coleman Novie O
- Yusoff Ahmad Faudzi
- Zainuddin Ahmad A
- Zakavi Seyed Rasoul
- Zamani Farhad
- Zambon Sabina
- Zampelas Antonis
- Zapata Maria Elisa
- Zaw Ko Ko
- Zdrojewski Tomasz
- Zejglicova Kristyna
- Zeljkovic Vrkic Tajana
- Zeng Yi
- Zhang Luxia
- Zhang Zhen-Yu
- Zhao Dong
- Zhao Ming-Hui
- Zhen Shiqi
- Zheng Yingfeng
- Zholdin Bekbolat
- Zhou Bin
- Zhu Dan
- Zins Marie
- Zitt Emanuel
- Zocalo Yanina
- Zoghlami Nada
- Zuñiga Cisneros Julio
- Čapková Naděžda
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/09/2021
- Field of study
Background
Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories.
Methods
We used data from 1990 to 2019 on people aged 30–79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined hypertension as having systolic blood pressure 140 mm Hg or greater, diastolic blood pressure 90 mm Hg or greater, or taking medication for hypertension. We applied a Bayesian hierarchical model to estimate the prevalence of hypertension and the proportion of people with hypertension who had a previous diagnosis (detection), who were taking medication for hypertension (treatment), and whose hypertension was controlled to below 140/90 mm Hg (control). The model allowed for trends over time to be non-linear and to vary by age.
Findings
The number of people aged 30–79 years with hypertension doubled from 1990 to 2019, from 331 (95% credible interval 306–359) million women and 317 (292–344) million men in 1990 to 626 (584–668) million women and 652 (604–698) million men in 2019, despite stable global age-standardised prevalence. In 2019, age-standardised hypertension prevalence was lowest in Canada and Peru for both men and women; in Taiwan, South Korea, Japan, and some countries in western Europe including Switzerland, Spain, and the UK for women; and in several low-income and middle-income countries such as Eritrea, Bangladesh, Ethiopia, and Solomon Islands for men. Hypertension prevalence surpassed 50% for women in two countries and men in nine countries, in central and eastern Europe, central Asia, Oceania, and Latin America. Globally, 59% (55–62) of women and 49% (46–52) of men with hypertension reported a previous diagnosis of hypertension in 2019, and 47% (43–51) of women and 38% (35–41) of men were treated. Control rates among people with hypertension in 2019 were 23% (20–27) for women and 18% (16–21) for men. In 2019, treatment and control rates were highest in South Korea, Canada, and Iceland (treatment >70%; control >50%), followed by the USA, Costa Rica, Germany, Portugal, and Taiwan. Treatment rates were less than 25% for women and less than 20% for men in Nepal, Indonesia, and some countries in sub-Saharan Africa and Oceania. Control rates were below 10% for women and men in these countries and for men in some countries in north Africa, central and south Asia, and eastern Europe. Treatment and control rates have improved in most countries since 1990, but we found little change in most countries in sub-Saharan Africa and Oceania. Improvements were largest in high-income countries, central Europe, and some upper-middle-income and recently high-income countries including Costa Rica, Taiwan, Kazakhstan, South Africa, Brazil, Chile, Turkey, and Iran.
Interpretation
Improvements in the detection, treatment, and control of hypertension have varied substantially across countries, with some middle-income countries now outperforming most high-income nations. The dual approach of reducing hypertension prevalence through primary prevention and enhancing its treatment and control is achievable not only in high-income countries but also in low-income and middle-income settings
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
- Author
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- Łuszczki E
- Šalaj S
- Ševčíková Ľ
- Żegleń M
- Publication venue
- Elsevier
- Publication date
- Field of study
Background Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. Methods We used data from 3663 population-based studies with 222 million participants that measured height and weight in representative samples of the general population. We used a Bayesian hierarchical model to estimate trends in the prevalence of different BMI categories, separately for adults (age ≥20 years) and school-aged children and adolescents (age 5–19 years), from 1990 to 2022 for 200 countries and territories. For adults, we report the individual and combined prevalence of underweight (BMI 2 SD above the median). Findings From 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. The combined prevalence increased in 162 countries (81%) for women and 140 countries (70%) for men with a posterior probability of at least 0·80. In 2022, the combined prevalence of underweight and obesity was highest in island nations in the Caribbean and Polynesia and Micronesia, and countries in the Middle East and north Africa. Obesity prevalence was higher than underweight with posterior probability of at least 0·80 in 177 countries (89%) for women and 145 (73%) for men in 2022, whereas the converse was true in 16 countries (8%) for women, and 39 (20%) for men. From 1990 to 2022, the combined prevalence of thinness and obesity decreased among girls in five countries (3%) and among boys in 15 countries (8%) with a posterior probability of at least 0·80, and increased among girls in 140 countries (70%) and boys in 137 countries (69%) with a posterior probability of at least 0·80. The countries with highest combined prevalence of thinness and obesity in school-aged children and adolescents in 2022 were in Polynesia and Micronesia and the Caribbean for both sexes, and Chile and Qatar for boys. Combined prevalence was also high in some countries in south Asia, such as India and Pakistan, where thinness remained prevalent despite having declined. In 2022, obesity in school-aged children and adolescents was more prevalent than thinness with a posterior probability of at least 0·80 among girls in 133 countries (67%) and boys in 125 countries (63%), whereas the converse was true in 35 countries (18%) and 42 countries (21%), respectively. In almost all countries for both adults and school-aged children and adolescents, the increases in double burden were driven by increases in obesity, and decreases in double burden by declining https://researchonline.ljmu.ac.uk/images/research_banner_face_lab_290.jpgunderweight or thinness. Interpretation The combined burden of underweight and obesity has increased in most countries, driven by an increase in obesity, while underweight and thinness remain prevalent in south Asia and parts of Africa. A healthy nutrition transition that enhances access to nutritious foods is needed to address the remaining burden of underweight while curbing and reversing the increase in obesity
Diminishing benefits of urban living for children and adolescents’ growth and development
- Author
- Abarca-Gómez L
- Abdeen ZA
- Abdrakhmanova S
- Abdul Rahim HF
- Abdurrahmonova Z
- Abril GL
- Abu-Rmeileh NM
- Acosta-Cazares B
- Adam I
- Adamczyk M
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- Aghazadeh-Attari J
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- Agyemang C
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- Al Hourani HM
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- Van Minh H
- Van Schoor NM
- van Valkengoed IGM
- Vanderschueren D
- Vanuzzo D
- Varbo A
- Varela-Moreiras G
- Vargas LN
- Varona-Pérez P
- Vasan SK
- Vasques DG
- Vega T
- Veidebaum T
- Velasquez-Melendez G
- Velika B
- Verloigne M
- Veronesi G
- Verschuren WMM
- Victora CG
- Viegi G
- Viet L
- Vik FN
- Vilar M
- Villalpando S
- Vioque J
- Virtanen JK
- Visvikis-Siest S
- Viswanathan B
- Vladulescu M
- Vlasoff T
- Vocanec D
- Vollenweider P
- Voutilainen A
- Vrijheid M
- Vrijkotte TGM
- Vrkic TZ
- Völzke H
- Wade AN
- Waldhör T
- Walton J
- Wambiya EOA
- Wang M-D
- Wang N
- Wang Q
- Wang X
- Wang Y-W
- Wang YX
- Wannamethee SG
- Wareham N
- Weber A
- Webster-Kerr K
- Wedderkopp N
- Weghuber D
- Wei W
- Weres A
- Werner B
- Westbury LD
- Whincup PH
- Wickramasinghe K
- Widhalm K
- Widyahening IS
- Wild PS
- Wilks RJ
- Willeit J
- Willeit P
- Williams J
- Wilsgaard T
- Wirth JP
- Więcek A
- Wojciech R
- Wojtyniak B
- Wolf K
- Wong A
- Wong EB
- Wong JE
- Wong NI
- Wong TY
- Wong-McClure RA
- Woo J
- Woodward M
- Wu FC
- Wu H-Y
- Wu J
- Wu LJ
- Wu S
- Wyszyńska J
- Xu H
- Xu L
- Yaacob NA
- Yamborisut U
- Yan W
- Yang L
- Yang X
- Yang Y
- Yardim N
- Yasuharu T
- Yiallouros PK
- Yngve A
- Yoosefi M
- Yoshihara A
- You QS
- You S-L
- Younger-Coleman NO
- Yu Y
- Yu Y-L
- Yusof SM
- Yusoff AF
- Yusoff MFM
- Zaccagni L
- Zafiropulos V
- Zainuddin AA
- Zakavi SR
- Zamani F
- Zambon S
- Zampelas A
- Zamrazilová H
- Zapata ME
- Zargar AH
- Zaw KK
- Zayed AA
- Zdrojewski T
- Zejglicova K
- Zeng Y
- Zhang L
- Zhang Z-Y
- Zhao D
- Zhao M-H
- Zhao W
- Zhecheva YV
- Zhen S
- Zheng W
- Zheng Y
- Zholdin B
- Zhou B
- Zhou M
- Zhu D
- Zins M
- Zitt E
- Zocalo Y
- Zoghlami N
- Zuziak M
- Ängquist L
- Čapková N
- Łuszczki E
- Šalaj S
- Ševčíková Ľ
- Żegleń M
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
AbstractOptimal growth and development in childhood and adolescence is crucial for lifelong health and well-being1–6. Here we used data from 2,325 population-based studies, with measurements of height and weight from 71 million participants, to report the height and body-mass index (BMI) of children and adolescents aged 5–19 years on the basis of rural and urban place of residence in 200 countries and territories from 1990 to 2020. In 1990, children and adolescents residing in cities were taller than their rural counterparts in all but a few high-income countries. By 2020, the urban height advantage became smaller in most countries, and in many high-income western countries it reversed into a small urban-based disadvantage. The exception was for boys in most countries in sub-Saharan Africa and in some countries in Oceania, south Asia and the region of central Asia, Middle East and north Africa. In these countries, successive cohorts of boys from rural places either did not gain height or possibly became shorter, and hence fell further behind their urban peers. The difference between the age-standardized mean BMI of children in urban and rural areas was <1.1 kg m–2 in the vast majority of countries. Within this small range, BMI increased slightly more in cities than in rural areas, except in south Asia, sub-Saharan Africa and some countries in central and eastern Europe. Our results show that in much of the world, the growth and developmental advantages of living in cities have diminished in the twenty-first century, whereas in much of sub-Saharan Africa they have amplified.</jats:p
Studying Mixing in Non-Newtonian Blue Maize Flour Suspensions Using Color Analysis
- Author
- A Castañeda-Ovando
- A Guida
- A Tamburini
- AC-Y Wong
- Adriana Ballescá-Estrada
- Alberto Aliseda
- Cecilia Rojas-de Gante
- CM Bryant
- CMS Trèche
- D Bulnes Abundis
- D Bulnes-Abundis
- D Patel
- DW King
- E Olmos
- EJ Aguirre-Ezkauriatza
- F Alberini
- F Fayolle
- G Chang
- G Méndez-Montealvo
- Grissel Trujillo-de Santiago
- GS Dhillon
- H Afshari-Jouybari
- H Lei
- H Shi
- HL Zhang
- HR Moreira
- J De la Rosa-MIllán
- J-C Gabelle
- JA Sánchez-Pérez
- JC Harrington
- JF Maingonnat
- JP Celli
- K Suzuki
- KJ Craig
- L Bouvier
- M Karsheva
- M Migliori
- M Soos
- M Urias-Peraldí
- Mario Moisés Alvarez
- MB Machado
- MC Núñez-Santiago
- MI Sánchez-Cervantes
- MM Alvarez
- N Domingues
- OS Wolfbeis
- PE Arratia
- Q Liu
- S Bhattacharya
- S Chen
- SH Ryu
- Silverio García-Lara
- SJ Curran
- TH Nguyen
- W Kelly
- Y Chen
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
The Telomerase Reverse Transcriptase Subunit from the Dimorphic Fungus Ustilago maydis
- Author
- A Brachmann
- A Cukusic
- AD Mozdy
- Antonio Celestino-Montes
- Arthur J. Lustig
- B Choudhary
- B Gillissen
- C Cifuentes-Rojas
- C Kelleher
- C Vazquez-Cruz
- C Yang
- CA Dalla Torre
- Candelario Vázquez-Cruz
- CB Harley
- CJ Cairney
- D Ding
- DL Gomez
- Dolores Bautista-España
- E Vollmeister
- ER Westin
- Erasmo Negrete-Abascal
- Estela Anastacio-Marcelino
- EY Yu
- F Banuett
- F Goldman
- GM Church
- Guillermo Horta-Valerdi
- HB Mann
- Hortensia Reyes-Cervantes
- I Flores
- J Kamper
- J Schirawski
- JD Podlevsky
- JE Puhalla
- K Masutomi
- KH Kalmbach
- L Armstrong
- MI Zvereva
- Milorad Kojic
- NW Kim
- P Huang
- P Martinez
- P Sanchez-Alonso
- P Sanchez-Alonso
- PA Guzman
- Patricia Sánchez-Alonso
- Plinio Guzmán
- R Dean
- R Holliday
- S Makovets
- S Redon
- SC Teng
- SE Gold
- T Brefort
- T Spellig
- T Tsukuda
- TS Lendvay
- V Lundblad
- V Walbot
- VD Longo
- WK Holloman
- XF Chen
- Y Hu
- YJ Chiang
- Z Ding
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Influence of Relining Post on the Bond Strength of Resin Cements
- Author
- Aguiar TC Saad JRC, Pinto SCS, Calixto LR, Lima DM, Silva MAS, Bandéca MC.
- AlEisa K Al-Dwairi ZN, Lynch E, Lynch CD.
- Arisu HD Kivanç BH, Saðlam BC, Þimþek E, Görgül G.
- Barjau-Escribano A Sancho-Bru JL, Forner-Navarro L, Rodríguez-Cervantes PJ, Pérez-Gónzález A, Sánchez-Marín FT.
- Bouillaguet S Troesch S, Wataha JC, Krejci I, Meyer JM, Pashley DH.
- Clavijo VG Reis JM, Kabbach W, Silva AL, Oliveira Junior OB, Andrade MF.
- D'Arcangelo C Cinelli M, De Angelis F, D'Amario M.
- D'Arcangelo C Zazzeroni S, D'Amario M, Vadini M, De Angelis F, Trubiani O, Caputi S.
- de Durâo Mauricio PJ González-López S, Aguilar-Mendoza JA, Félix S, González-Rodríguez MP.
- Dimitrouli M Günay H, Geurtsen W, Lührs AK.
- Erdemir U Mumcu E, Topcu FT, Yildiz E, Yamanel K, Akyol M.
- Faria-e-Silva AL Pedrosa-Filho Cde F, Menezes Mde S, Silveira DM, Martins LR.
- Fokkinga WA Kreulen CM, Vallittu PK, Creugers NH.
- Goracci C Ferrari M.
- Goracci C Sadek FT, Fabianelli A, Tay FR, Ferrari M.
- Grandini S Goracci C, Monticelli F, Borracchini A, Ferrari M.
- Kececi AD Ureyen Kaya B, Adanir N.
- Mosharraf R Haerian A.
- Othman HI Elshinawy MI, Abdelaziz KM.
- Pereira JR Lins do Valle A, Ghizoni JS, Lorenzoni FC, Ramos MB, Dos Reis Só MV.
- Schwartz RS Robbins JW.
- Zhang L Huang L, Xiong Y, Fang M, Chen JH, Ferrari M.
- Zorba YO Erdemir A, Turkyilmaz A, Eldeniz AU.
- Publication venue
- 'Jaypee Brothers Medical Publishing'
- Publication date
- Field of study
Metal bioavailability and toxicity in freshwaters
- Author
- A Eroglu
- A Munné
- A Santoro
- A Smiejan
- A Sofyan
- A Stockdale
- AADS Machado
- ACS Cruz Da
- AD Laurie
- AE El-Enany
- AH Rosa
- AK Shanker
- ALS Rodrigues
- AM Farag
- AM Gower
- B Carney Almroth
- B Jezierska
- B Koukal
- B Nunes
- BA Ahner
- BA Butler
- BI Escher
- Brauner CJ
- C Cervantes
- C Munger
- C Sarin
- CCME Canadian Council of Ministers of the Environment
- CCME Canadian Council of Ministers of the Environment
- CJ Brauner
- CJ Brauner
- CP Marasinghe Wadige
- CW Hickey
- D Gasparatos
- D Saglam
- DA Monteiro
- DA Vignati
- DA Vignati
- Daniel Forsin Buss
- Danielly de Paiva Magalhães
- Darcilio Fernandes Baptista
- DB Kosolapov
- De Schamphelaere
- DG Heijerick
- DM McKnight
- DM Templeton
- DM Templeton
- DM Toro Di
- DP Magalhães
- DR Livingstone
- E Has-Schön
- E Kurek
- E Pinto
- E Tipping
- E Tipping
- EH Jho
- EJ Mitchell
- EK Raftopoulou
- ER Weiner
- FAA Al-Rub
- FAA Al-Rub
- G Atli
- G Blackmore
- GR Phillips
- GR Phillips
- H Karadede
- H Marcussen
- H Schat
- HE Allen
- HP Singh
- I Komjarova
- I Komjarova
- I Komjarova
- I Lavoie
- I Rodea-Palomares
- J Forsberg
- J Gonçalves
- J Han
- J Hellou
- J Klinck
- JA Hagger
- JC Amiard
- JC Rocha
- JC Rocha
- JF Alcedo
- JG Hering
- JG Lee
- JG Richards
- JHR Kägi
- JW Ho
- JW Rudd
- K Lock
- K Nishikawa
- KA Keteles
- KA Robinson
- KA Schamphelaere De
- KAC Schamphelaere De
- KAC Schamphelaere De
- KL Goodyear
- KL Wilde
- KN Baer
- L Zhang
- LK Pandey
- M Enk
- M Grosell
- M Kamo
- M Oven
- M Pesavento
- M Prica
- M Sevcikova
- M Yamazaki
- MA Turner
- MC Bisinoti
- MC Zaccaro
- MG Vijver
- MI Nystrand
- MJ Tamas
- MK Schubauer-Berigan
- ML Schwartz
- MT Monteiro
- MTK Tsui
- Mônica Regina da Costa Marques
- N Ospina-Alvarez
- NJ Robinson
- NM Franklin
- NM Franklin
- O Čelechovská
- P Alcorlo
- P Bjerregaard
- P Gunkel-Grillon
- P Sánchez-Marín
- PA Olsvik
- PC Nagajyoti
- PE Lombardi
- PG McWilliams
- PGC Campbell
- PR Paquin
- PS Rainbow
- PSS Bezerra
- Q Zhou
- R Cornelis
- R Henderson
- R Reeve
- R Weltens
- RC Playle
- RC Playle
- RC Santore
- RW Winner
- S Baken
- S Clemens
- S Lemaire
- S Niyogi
- S Niyogi
- S Sinha
- S Siripornadulsil
- S Stankovic
- SE Hook
- SE Hook
- SM Macfie
- SR Smith
- SS Sharma
- SSS Sarma
- SV Matagi
- T Backhaus
- T Kozlova
- TE English
- TS Schmidt
- TT Duong
- U Borgmann
- U Memmert
- USEPA United States Environmental Protection Agency
- V Funes
- V Tsiridis
- V Velma
- VH Resh
- W Oueslati
- W-X Wang
- W-X Wang
- WG Wallace
- WG Wallace
- WG Wallace
- WH Clements
- WH Clements
- WH Clements
- WJ Berry
- Y Mu
- Y Tepe
- Y Wei
- YY Mosleh
- ZZ Chen
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study