22 research outputs found
Frequency of the different mutations causing spinocerebellar ataxia (SCA1, SCA2, MJD/SCA3 and DRPLA) in a large group of Brazilian patients
Coordenação da assistĂŞncia prestada Ă s pessoas que vivem com HIV/AIDS em um municĂpio do Estado de SĂŁo Paulo, Brasil
Cloning, Expression, Purification, and Characterization of a Novel Esterase from Lactobacillus plantarum
Atividade agrĂcola e externalidade ambiental: uma análise a partir do uso de agrotĂłxicos no cerrado brasileiro
The effective population size of malaria mosquitoes: large impact of vector control.
Malaria vectors in sub-Saharan Africa have proven themselves very difficult adversaries in the global struggle against malaria. Decades of anti-vector interventions have yielded mixed results--with successful reductions in transmission in some areas and limited impacts in others. These varying successes can be ascribed to a lack of universally effective vector control tools, as well as the development of insecticide resistance in mosquito populations. Understanding the impact of vector control on mosquito populations is crucial for planning new interventions and evaluating existing ones. However, estimates of population size changes in response to control efforts are often inaccurate because of limitations and biases in collection methods. Attempts to evaluate the impact of vector control on mosquito effective population size (N(e)) have produced inconclusive results thus far. Therefore, we obtained data for 13-15 microsatellite markers for more than 1,500 mosquitoes representing multiple time points for seven populations of three important vector species--Anopheles gambiae, An. melas, and An. moucheti--in Equatorial Guinea. These populations were exposed to indoor residual spraying or long-lasting insecticidal nets in recent years. For comparison, we also analyzed data from two populations that have no history of organized vector control. We used Approximate Bayesian Computation to reconstruct their demographic history, allowing us to evaluate the impact of these interventions on the effective population size. In six of the seven study populations, vector control had a dramatic impact on the effective population size, reducing N(e) between 55%-87%, the exception being a single An. melas population. In contrast, the two negative control populations did not experience a reduction in effective population size. This study is the first to conclusively link anti-vector intervention programs in Africa to sharply reduced effective population sizes of malaria vectors
A mulher climatérica
O autor faz uma revisĂŁo sobre os diversos aspectos envolvidos na abordagem clĂnica do climatĂ©rio. É enfatizado o papel do exercĂcio, salientando que os dados da literatura, relacionando a atividade fĂsica com a sĂndrome climatĂ©rica, sĂŁo, muitas vezes, oriundos de estudos com importantes falhas metodolĂłgicas