IoT-based solution to reduce waste and promote a sustainable farming industry

Waste and the necessity to increase sustainability in the farming industry are some of the challenges addressed in the agri-food chain. With the potential of digital technologies, e.g., the Internet of Things (IoT) and Artificial Intelligence, to revolutionize agriculture by enabling more efficient and intelligent monitoring, system architecture and IoT nodes were developed to support relevant parameters for composing a Sustainability Index for the Bio-economy (siBIO). These nodes are scalable, modular, capable of meeting on-demand production needs, and provide a cost-effective alternative to commercial solutions or manual data collection methods. The collected data is transmitted to middleware and then stored, analyzed, and displayed on a user-friendly dashboard, providing data to siBIO and consequently contributing to a more sustainable farming industry and reducing waste of resources and food. The results include the implementation of IoT nodes in a case study involving a vineyard and an apple orchard. The nodes are successfully collecting data on environmental, operational, and energy parameters such as temperature, air humidity, soil moisture, precipitation, and water and electricity consumption for irrigation. The tests of data transmission and collection, functionality and robustness of the proposed solution were promising, offering a way to quantify the sustainability index and facilitate the exchange of agricultural information in a reliable and standardized way.This work has been conducted under the project BIOMA Bioeconomy integrated solutions for the mobilization of the Agro-food market (POCI-01-0247-FEDER-046112). This work has been also supported by the Foundation for Sci- ence and Technology (FCT, Portugal) through national funds FCT/MCTES (PIDDAC) to CeDRI (UIDB/05757/2020 and UIDP/05757/2020) and SusTEC (LA/P/0007/2021). Authors Gustavo Funchal and Vict oria Melo thank the FCT for the PhD Grants 2022.13712.BD and 2022.13868.BD, respectively.info:eu-repo/semantics/publishedVersio

Aptidão Agrícola e adequação de uso das terras do assentamento-acampamento Sebastião Lan I e II.

A Aptidão Agrícola e Adequação de Uso das Terras do Assentamento- Acampamento Sebastião Lan I e II faz parte do Projeto ?Caracterização Pedológica e Recomendações de Manejo das Áreas do Assentamento- Acampamento Sebastião Lan I e II?, do convênio entre o INCRA e a Embrapa Solos. A área situa-se no município de Silva Jardim-RJ, entre as coordenadas geográficas 22°32?30" e 22°35?30" de latitude Sul e 42°15?00" e 42°11?00" de longitude Oeste, com aproximadamente 2.000 ha. As principais classes de solos são: Cambissolos Háplicos, Gleissolos Háplicos, Gleissolos Tiomórficos e Organossolos Tiomórficos. A Aptidão Agrícola das Terras dominante na área é a classe 6, sem aptidão para uso agrícola e indicada para preservação da fauna e da flora, ocupando 58,1%. Os impedimentos principais desses solos são: ocorrência generalizada de alumínio trocável em níveis tóxicos; ocorrência localizada, porém frequente, de caráter tiomórfico; intensa oxidação da matéria orgânica; acidez generalizada da água e do solo, carência generalizada de nutrientes e excesso de água. As terras com aptidão Regular para lavouras, referentes às classes 2(a)bc e 2abc, ocupam 24,2% da área. As terras enquadradas como classe 4(p), Restrita para pastagem plantada, ocupam 13,6%. Em termos de Adequação de Uso, 60,5% da área não são indicadas para uso agrícola, sendo 56,1% Inaptas e 4,4% de Reserva Legal. As áreas Aptas perfazem apenas 27% e as áreas Restritas 11,3% de Sebastião Lan. O manejo do solo deverá, obrigatoriamente, incluir o manejo do lençol freático por meio de comportas, minimizando os efeitos da sulfatação da área, necessitando de maiores estudos para a compreensão do comportamento de culturas sob tais condições.bitstream/item/87963/1/BPD-207-Aptidao-Assentamento-Lan-I-e-Lan-II.pd

Two new species of Phalangopsis Serville, 1831 (Orthoptera: Grylloidea: Phalangopsidae) from Brazilian Amazon Forest

We describe here two new species of the genus Phalangopsis Serville, 1831 from the Brazilian Amazon Forest. The male genitalia and the female copulatory papilla were described, and a combination of diagnostic characteristics was given to separate both new species from the other described species. The principal morphological characteristics of this genus were discussed.Aqui foram descritas duas espécies novas do gênero Phalangopsis Serville, 1831 da Floresta Amazônica brasileira. A genitália masculina e a papila copulatória feminina são descritas, bem como uma combinação de características diagnósticas para separar ambas as novas espécies das outras espécies descritas. As principais características morfológicas foram discutidas

Mutations of the GLA gene in young patients with stroke: the PORTYSTROKE study-screening genetic conditions in Portuguese young stroke patients

BACKGROUND AND PURPOSE: Fabry disease is an X-linked monogenic disorder caused by mutations in the GLA gene. Recent data suggest that stroke in young adults may be associated with Fabry disease. We aimed to ascertain the prevalence of this disorder among young adult patients with stroke in Portugal by GLA genotyping. METHODS: During 1 year, all patients aged 18 to 55 years with first-ever stroke, who were admitted into any of 12 neurology hospital departments in Portugal, were prospectively enrolled (n=625). Ischemic stroke was classified according to Trial of Org 10172 in Acute Stroke Treatment criteria. Alpha-galactosidase activity was further assayed in all patients with GLA mutations. RESULTS: Four hundred ninety-three patients (mean age, 45.4 years; 61% male) underwent genetic analyses: 364 with ischemic stroke, 89 with intracerebral hemorrhage, 26 with subarachnoid hemorrhage, and 14 with cerebral venous thrombosis. Twelve patients had missense GLA mutations: 9 with ischemic stroke (p.R118C: n=4; p.D313Y: n=5), including 5 patients with an identified cause of stroke (cardiac embolism: n=2; small vessel disease: n=2; other cause: n=1), 2 with intracerebral hemorrhage (p.R118C: n=1; p.D313Y: n=1), and one with cerebral venous thrombosis (p.R118C: n=1). Leukocyte alpha-galactosidase activity was subnormal in the hemizygous males and subnormal or low-normal in the heterozygous females. Estimated prevalence of missense GLA mutations was 2.4% (95% CI, 1.3% to 4.1%). CONCLUSIONS: Despite a low diagnostic yield, screening for GLA mutations should probably be considered in different types of stroke. Restricting investigation to patients with cryptogenic stroke may underestimate the true prevalence of Fabry disease in young patients with stroke

The Portuguese Society of Rheumatology position paper on the use of biosimilars

Biotechnological drugs have become a fundamental resource for the treatment of rheumatic patients. Patent expiry of some of these drugs created the opportunity for biopharmaceutical manufacturers to develop biosimilar drugs intended to be as efficacious as the originator product but with a lower cost to healthcare systems. Due to the complex manufacturing process and highly intricate structure of biologicals, a biosimilar can never be an exact copy of its reference product. Consequently, regulatory authorities issued strict preclinical and clinical guidelines to ensure safety and efficacy equivalence and, in September 2013, the biosimilar of infliximab was the first biosimilar monoclonal antibody to be authorized for use in the European Union. The current document is a position statement of the "Sociedade Portuguesa de Reumatologia" (Portuguese Society of Rheumatology) on the use of biosimilar drugs in rheumatic diseases. Two systematic literature reviews were performed, one concerning clinical trials and the other one concerning international position papers on biosimilars. The results were presented and discussed in a national meeting and a final position document was discussed, written and approved by Portuguese rheumatologists. Briefly, this position statement is contrary to automatic substitution of the originator by the biosimilar, defends either a different INN or the prescription by brand name, supports that switching between biosimilars and the originator molecule should be done after at least 6 months of treatment and based on the attending physician decision and after adequate patient information, recommends the registration of all biosimilar treated patients in Reuma.pt for efficacy, safety and immunogenicity surveillance, following the strategy already ongoing for originators, and opposes to extrapolation of indications approved to the originator to completely different diseases and/or age groups without adequate pre-clinical, safety or efficacy data.info:eu-repo/semantics/publishedVersio

Portuguese-Brazilian Evidence-Based Guideline on the Management of Hyperglycemia in Type 2 Diabetes Mellitus

Background: In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and Portugal was established to develop an evidence-based guideline for treatment of hyperglycemia in T2DM. Methods: MEDLINE (via PubMed) was searched for randomized clinical trials, meta-analyses, and observational studies related to diabetes treatment. When there was insufficient high-quality evidence, expert opinion was sought. Updated positions on treatment of T2DM patients with heart failure (HF), atherosclerotic CV disease (ASCVD), chronic kidney disease (CKD), and patients with no vascular complications were developed. The degree of recommendation and the level of evidence were determined using predefined criteria. Results and conclusions: In non-pregnant adults, the recommended HbA1c target is below 7%. Higher levels are recommended in frail older adults and patients at higher risk of hypoglycemia. Lifestyle modification is recommended at all phases of treatment. Metformin is the first choice when HbA1c is 6.5-7.5%. When HbA1c is 7.5-9.0%, dual therapy with metformin plus an SGLT2i and/or GLP-1RA (first-line antidiabetic agents, AD1) is recommended due to cardiovascular and renal benefits. If an AD1 is unaffordable, other antidiabetic drugs (AD) may be used. Triple or quadruple therapy should be considered when HbA1c remains above target. In patients with clinical or subclinical atherosclerosis, the combination of one AD1 plus metformin is the recommended first-line therapy to reduce cardiovascular events and improve blood glucose control. In stable heart failure with low ejection fraction ( 30 mL/min/1.73 m2, metformin plus an SGLT-2i is recommended to reduce cardiovascular mortality and heart failure hospitalizations and improve blood glucose control. In patients with diabetes-associated chronic kidney disease (CKD) (eGFR 30-60 mL/min/1.73 m2 or eGFR 30-90 mL/min/1.73 m2 with albuminuria > 30 mg/g), the combination of metformin and an SGLT2i is recommended to attenuate loss of renal function, reduce albuminuria and improve blood glucose control. In patients with severe renal failure, insulin-based therapy is recommended to improve blood glucose control. Alternatively, GLP-1RA, DPP4i, gliclazide MR and pioglitazone may be considered to reduce albuminuria. In conclusion, the current evidence supports individualizing anti-hyperglycemic treatment for T2DM.info:eu-repo/semantics/publishedVersio

Unveiling relationships between crime and property in England and Wales via density scale-adjusted metrics and network tools

Scale-adjusted metrics (SAMs) are a significant achievement of the urban scaling hypothesis. SAMs remove the inherent biases of per capita measures computed in the absence of isometric allometries. However, this approach is limited to urban areas, while a large portion of the world’s population still lives outside cities and rural areas dominate land use worldwide. Here, we extend the concept of SAMs to population density scale-adjusted metrics (DSAMs) to reveal relationships among different types of crime and property metrics. Our approach allows all human environments to be considered, avoids problems in the definition of urban areas, and accounts for the heterogeneity of population distributions within urban regions. By combining DSAMs, cross-correlation, and complex network analysis, we find that crime and property types have intricate and hierarchically organized relationships leading to some striking conclusions. Drugs and burglary had uncorrelated DSAMs and, to the extent property transaction values are indicators of affluence, twelve out of fourteen crime metrics showed no evidence of specifically targeting affluence. Burglary and robbery were the most connected in our network analysis and the modular structures suggest an alternative to "zero-tolerance" policies by unveiling the crime and/or property types most likely to affect each other