1,076 research outputs found
Parallel Multi-Objective Evolutionary Algorithms: A Comprehensive Survey
Multi-Objective Evolutionary Algorithms (MOEAs) are powerful search techniques that have been extensively used to solve difficult problems in a wide variety of disciplines. However, they can be very demanding in terms of computational resources. Parallel implementations of MOEAs (pMOEAs) provide considerable gains regarding performance and scalability and, therefore, their relevance in tackling computationally expensive applications. This paper presents a survey of pMOEAs, describing a refined taxonomy, an up-to-date review of methods and the key contributions to the field. Furthermore, some of the open questions that require further research are also briefly discussed
Docencia de arquitectura orientada a servicios
Este trabajo presenta los contenidos del curso “Web
2.0: Arquitectura Orientada a Servicios en Java” de
la Escuela de Posgrado de la Universidad de Granada.
El objetivo del curso es familiarizar al alumno
con la programación de ServiciosWeb. Dada la gran
variedad de técnicas disponibles para utilizar Arquitectura
Orientada a Servicios, se presentan los siguientes
temas: utilización de protocolos bien definidos
para comunicación y contrato (SOAP y WSDL),
creación de Web Services con JAX-WS y orquestación
de ServiciosWeb con BPEL. Al final del curso,
el alumno será capaz de crear, utilizar y mantener
Servicios Web para el desarrollo de aplicaciones interempresariales,
utilizando servicios creados o ya
disponibles en la web, así como la orquestación lógica
de los mismos.SUMMARY: This work presents the contents of the course
“Web 2.0: Service Oriented Architecture on Java”
from the Graduate School of the University of Granada.
The course objective is to familarize students
with Web Services programming. Due to the wide
variety of available technologies, several subjects
are presented: the usage of well-defined protocols
to contract and communication (SOAP and WSDL),
web services creation using JAX-WS, and service
orchestration with BPEL. At the end of the course,
students will be capable to create, use and manage
Web Services for business applications, using new
or available services in the web, and also their logical
orchestration.Peer Reviewe
Fiabilidad y validez de las mediciones en hombro y codo: análisis de una aplicación de Android y un goniómetro
El texto completo de este trabajo no está disponible en el Repositorio Académico UPC por restricciones de la casa editorial donde ha sido publicado.Carta al EditorRevisión por pare
Fractional reaction-diffusion equations
In a series of papers, Saxena, Mathai, and Haubold (2002, 2004a, 2004b)
derived solutions of a number of fractional kinetic equations in terms of
generalized Mittag-Leffler functions which provide the extension of the work of
Haubold and Mathai (1995, 2000). The subject of the present paper is to
investigate the solution of a fractional reaction-diffusion equation. The
results derived are of general nature and include the results reported earlier
by many authors, notably by Jespersen, Metzler, and Fogedby (1999) for
anomalous diffusion and del-Castillo-Negrete, Carreras, and Lynch (2003) for
reaction-diffusion systems with L\'evy flights. The solution has been developed
in terms of the H-function in a compact form with the help of Laplace and
Fourier transforms. Most of the results obtained are in a form suitable for
numerical computation.Comment: LaTeX, 17 pages, corrected typo
Solution of generalized fractional reaction-diffusion equations
This paper deals with the investigation of a closed form solution of a
generalized fractional reaction-diffusion equation. The solution of the
proposed problem is developed in a compact form in terms of the H-function by
the application of direct and inverse Laplace and Fourier transforms.
Fractional order moments and the asymptotic expansion of the solution are also
obtained.Comment: LaTeX, 18 pages, corrected typo
Molecular characterization of thioester-containing proteins in Biomphalaria glabrata and their differential gene expression upon Schistosoma mansoni exposure
Schistosomiasis is a disease caused by trematode parasites of the genus Schistosoma that affects approximately 200 million people worldwide. Schistosomiasis has been a persistent problem in endemic areas as there is no vaccine available, currently used anti-helmintic medications do not prevent reinfection, and most concerning, drug resistance has been documented in laboratory and field isolates. Thus, alternative approaches to curtail this human disease are warranted. Understanding the immunobiology of the obligate intermediate host of these parasites, which include the freshwater snail Biomphalaria glabrata, may facilitate the development of novel methods to stop or reduce transmission to humans. Molecules from the thioester-containing protein (TEP) superfamily have been shown to be involved in immunological functions in many animals including corals and humans. In this study we identified, characterized, and compared TEP transcripts and their expression upon S. mansoni exposure in resistant and susceptible strains of B. glabrata snails. Results showed the expression of 11 unique TEPs in B. glabrata snails. These transcripts present high sequence identity at the nucleotide and putative amino acid levels between susceptible and resistant strains. Further analysis revealed differences in several TEPs’ constitutive expression levels between resistant and susceptible snail strains, with C3-1, C3-3, and CD109 having higher constitutive expression levels in the resistant (BS90) strain, whereas C3-2 and TEP-1 showed higher constitutive expression levels in the susceptible (NMRI) strain. Furthermore, TEP-specific response to S. mansoni miracidia exposure reiterated their differential expression, with resistant snails upregulating the expression of both TEP-4 and TEP-3 at 2 h and 48 h post-exposure, respectively. Further understanding the diverse TEP genes and their functions in invertebrate animal vectors will not only expand our knowledge in regard to this ancient family of immune proteins, but also offer the opportunity to identify novel molecular targets that could aid in the efforts to develop control methods to reduce schistosomiasis transmission
Study of the solvatochromic effect on natural phenolic compounds
Se describen las características espectrofluorimétricas de dos derivados de quercetina aislados de las hojas de
Flaveria bidentis, un derivado de 6-prenilpinocembrina, aislado de las raíces de Dalea elegans y un compuesto de
estructura antraquinónica aislado de las hojas de Heterophyllaea pustulata. Todos ellos presentan espectros de
absorción con máximos en la región UV-visible acordes con los grupos cromóforos presentes en su estructura. Los
cuatro compuestos estudiados presentan fluorescencia nativa. La posición de los máximos de emisión de fluorescencia
se modifica en función del disolvente. Los desplazamientos producidos están relacionados con el diferente grado
de solvatación de las moléculas en estado excitado según la polaridad del disolvente. La adición de ácidos minerales
provoca desplazamientos en los máximos de fluorescencia concordantes con los ya descritos para compuestos de
estructura similar. Estas modificaciones espectrales tienen un gran interés analítico desde el punto de vista de la
identificación y caracterización de productos naturales de estructura fenólica.The spectrofluorimetric behaviour of two derivatives of quercetin isolated from the leaves of Flaveria bidentis, a
derivative of 6-prenylpinocembrin isolated from the roots of Dalea elegans and an anthraquinonic derivative isolated
from the leaves of Heterophyllaea pustulata, is described. The UV-visible absorption spectra of these compounds
exhibit the maximum values corresponding to the chromophores present in each structure. All of the compounds studied
show native fluorescence in different solvents. The maximum shift in fluorescence emission to the red spectral region
when the polarity of the solvents is increased, can be attributed to varying degrees of solvation in the excited state in
the different solvents. Additions of small amounts of H2SO4 cause shifts in excitation and emission wavelengths, in
agreement with those described for compounds with similar chemical structures. Such fluorescent spectral changes are
of considerable analytical interest, given that they allow the presence of phenolic compounds in the extracts of natural
plant material to be detected easily.Program for University Co-operation conve-
ned in 2001 by Agencia Española de Cooperación Internacional (AECI)
Towards Machine Wald
The past century has seen a steady increase in the need of estimating and
predicting complex systems and making (possibly critical) decisions with
limited information. Although computers have made possible the numerical
evaluation of sophisticated statistical models, these models are still designed
\emph{by humans} because there is currently no known recipe or algorithm for
dividing the design of a statistical model into a sequence of arithmetic
operations. Indeed enabling computers to \emph{think} as \emph{humans} have the
ability to do when faced with uncertainty is challenging in several major ways:
(1) Finding optimal statistical models remains to be formulated as a well posed
problem when information on the system of interest is incomplete and comes in
the form of a complex combination of sample data, partial knowledge of
constitutive relations and a limited description of the distribution of input
random variables. (2) The space of admissible scenarios along with the space of
relevant information, assumptions, and/or beliefs, tend to be infinite
dimensional, whereas calculus on a computer is necessarily discrete and finite.
With this purpose, this paper explores the foundations of a rigorous framework
for the scientific computation of optimal statistical estimators/models and
reviews their connections with Decision Theory, Machine Learning, Bayesian
Inference, Stochastic Optimization, Robust Optimization, Optimal Uncertainty
Quantification and Information Based Complexity.Comment: 37 page
Docencia de arquitectura orientada a servicios
Este trabajo presenta los contenidos del curso “Web
2.0: Arquitectura Orientada a Servicios en Java” de
la Escuela de Posgrado de la Universidad de Granada.
El objetivo del curso es familiarizar al alumno
con la programación de ServiciosWeb. Dada la gran
variedad de técnicas disponibles para utilizar Arquitectura
Orientada a Servicios, se presentan los siguientes
temas: utilización de protocolos bien definidos
para comunicación y contrato (SOAP y WSDL),
creación de Web Services con JAX-WS y orquestación
de ServiciosWeb con BPEL. Al final del curso,
el alumno será capaz de crear, utilizar y mantener
Servicios Web para el desarrollo de aplicaciones interempresariales,
utilizando servicios creados o ya
disponibles en la web, así como la orquestación lógica
de los mismos
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