1,175 research outputs found
High-affinity glucose uptake in Saccharomyces cerevisiae is not dependent on the presence of glucose-phosphorylating enzymes
Application of diagnostic techniques to an experimental aircraft fuel rig
An important issue for Aerospace and Defence Systems providers is how to
reduce the risks associated with installing a new Fault Detection Tool (FDT) on a system.
It is highly desirable that some degree of assessment, selection and validation is carried
out before the FDT is integrated with the system. This paper describes the initial phases
of a project to investigate the processes behind the assessment and validation using an
Experimental Aircraft Fuel Rig (referred to as the Advanced Diagnostic Test-bed ADT).
This paper also presents results from preliminary verification and validation work that has
been used on a mathematical model of the ADT, and also some results from some initial
diagnostic technique assessment that has been performed using real experimental data
from the ADT and simulated data from mathematical models
Multi-annual and multi-decadal evolution of sediment accretion in a saltmarsh of the French Atlantic coast: Implications for carbon sequestration
Coastal marshes offer natural solutions for adapting to and mitigating the effects of climate change and sea level rise. However, the resilience of the marsh physical system and, with it, the ecosystem services that it provides, is largely site specific. This calls for the increase in the spatial cover of coastal marsh studies in order to assess the controlling factors of marsh evolution, and their long-term carbon storage capacities. Here, we study the spatio-temporal variations in sedimentation rates and organic carbon (OC) sequestration capacity of the macrotidal minerogenic saltmarshes in Aiguillon Bay, belonging to one of the largest French coastal marshes. Supported by aerial photographs and satellite image analysis, we first show that saltmarshes of the Aiguillon Bay have prograded at very high rates, up to 14 m yr−1 since 1950. Sediment accumulation rates (SAR) were estimated at both multi-annual to multi-decadal scales based on two approaches: (i) LiDAR-based digital elevation models from multiple acquisition dates (2010–2021); and (ii) depth profiles of 210Pb in excess and 137Cs in sediment cores collected along cross-shore transects in the saltmarshes. Long-term SAR range from 0.8 to 2.2 cm yr−1 and are among the highest reported worldwide for equivalent systems. The positive accretion balance (accretion rate minus local sea-level rise rate) provides important clues on marsh resilience suggesting that the Aiguillon Bay is currently able to adapt to rising sea level. Despite relatively low organic carbon content (1.3–6.0%), high SAR leads to high carbon sequestration rates (99–345 gC m−2 yr−1; or a mean value of 2.5 Mg C ha−1 yr−1). The isotopic signature of sediment OC reveals a significant and rapid decomposition of organic material in surface cores, while allochthonous sediment of marine origin dominates the signature of chemically-stable OC of marsh sediments. This implies that the carbon sequestration capacity of minerogenic saltmarshes, such as those of the Pertuis Charentais, also depends upon the wealth of adjacent coastal environments through high sediment supply and primary productivity.Evolution de l'identité patrimoniale des marais des Pertuis Charentais en réponse à l'aléa de submersion marin
Global Emergence of Trimethoprim/Sulfamethoxazole Resistance in Stenotrophomonas maltophilia Mediated by Acquisition of sul Genes
The first sul2 genes have been found in S. maltophilia from several different countries
GUP1 and its close homologue GUP2, encoding multi-membrane-spanning proteins involved in active glycerol uptake in Saccharomyces cerevisiae
Many yeast species can utilise glycerol, both as sole carbon source and as an osmolyte. In Saccharomyces cerevisiae, physiological studies have previously shown the presence of an active uptake system driven by electrogenic proton symport. We have used transposon mutagenesis to isolate mutants affected in the transport of glycerol into the cell. Here we present the identification of YGL084c, encoding a multi-membrane-spanning protein, as being essential for proton symport of glycerol into Saccharomyces cerevisiae. The gene is named GUP1 (Glycerol UPtake) and is important for growth on glycerol as carbon and energy source, as well as for osmotic protection by added glycerol, of a strain deficient in glycerol production. Another ORF, YPL189w, presenting a high degree of homology to YGL084c, similarly appears to be involved in active glycerol uptake in salt-containing glucose-based media in strains deficient in glycerol production. Analogously, this gene is named GUP2. To our knowledge, this is the first report on a gene product involved in active transport of glycerol in yeasts. Mutations with the same phenotypes occurred in two other open reading frames of previously unknown function, YDL074c and YPL180w.Comunidade Europeia (CE) - contract BIO4-CT95-0161
A SAT Approach to Clique-Width
Clique-width is a graph invariant that has been widely studied in
combinatorics and computer science. However, computing the clique-width of a
graph is an intricate problem, the exact clique-width is not known even for
very small graphs. We present a new method for computing the clique-width of
graphs based on an encoding to propositional satisfiability (SAT) which is then
evaluated by a SAT solver. Our encoding is based on a reformulation of
clique-width in terms of partitions that utilizes an efficient encoding of
cardinality constraints. Our SAT-based method is the first to discover the
exact clique-width of various small graphs, including famous graphs from the
literature as well as random graphs of various density. With our method we
determined the smallest graphs that require a small pre-described clique-width.Comment: proofs in section 3 updated, results remain unchange
Grain Surface Models and Data for Astrochemistry
AbstractThe cross-disciplinary field of astrochemistry exists to understand the formation, destruction, and survival of molecules in astrophysical environments. Molecules in space are synthesized via a large variety of gas-phase reactions, and reactions on dust-grain surfaces, where the surface acts as a catalyst. A broad consensus has been reached in the astrochemistry community on how to suitably treat gas-phase processes in models, and also on how to present the necessary reaction data in databases; however, no such consensus has yet been reached for grain-surface processes. A team of ∼25 experts covering observational, laboratory and theoretical (astro)chemistry met in summer of 2014 at the Lorentz Center in Leiden with the aim to provide solutions for this problem and to review the current state-of-the-art of grain surface models, both in terms of technical implementation into models as well as the most up-to-date information available from experiments and chemical computations. This review builds on the results of this workshop and gives an outlook for future directions
Detector Description and Performance for the First Coincidence Observations between LIGO and GEO
For 17 days in August and September 2002, the LIGO and GEO interferometer
gravitational wave detectors were operated in coincidence to produce their
first data for scientific analysis. Although the detectors were still far from
their design sensitivity levels, the data can be used to place better upper
limits on the flux of gravitational waves incident on the earth than previous
direct measurements. This paper describes the instruments and the data in some
detail, as a companion to analysis papers based on the first data.Comment: 41 pages, 9 figures 17 Sept 03: author list amended, minor editorial
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Search for supersymmetry with a dominant R-parity violating LQDbar couplings in e+e- collisions at centre-of-mass energies of 130GeV to 172 GeV
A search for pair-production of supersymmetric particles under the assumption
that R-parity is violated via a dominant LQDbar coupling has been performed
using the data collected by ALEPH at centre-of-mass energies of 130-172 GeV.
The observed candidate events in the data are in agreement with the Standard
Model expectation. This result is translated into lower limits on the masses of
charginos, neutralinos, sleptons, sneutrinos and squarks. For instance, for
m_0=500 GeV/c^2 and tan(beta)=sqrt(2) charginos with masses smaller than 81
GeV/c^2 and neutralinos with masses smaller than 29 GeV/c^2 are excluded at the
95% confidence level for any generation structure of the LQDbar coupling.Comment: 32 pages, 30 figure
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