10 research outputs found
Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome
- Author
- Publication venue
- Cold Spring Harbor Laboratory Press
- Publication date
- 14/07/2008
- Field of study
Down syndrome (DS) is a genetic disorder arising from the presence of a third copy of the human chromosome 21 (Hsa21). Recently, OâDoherty and colleagues in an earlier study generated a new genetic mouse model of DS (Tc1) that carries an almost complete Hsa21. Since DS is the most common genetic cause of mental retardation, we have undertaken a detailed analysis of cognitive function and synaptic plasticity in Tc1 mice. Here we show that Tc1 mice have impaired spatial working memory (WM) but spared long-term spatial reference memory (RM) in the Morris watermaze. Similarly, Tc1 mice are selectively impaired in short-term memory (STM) but have intact long-term memory (LTM) in the novel object recognition task. The pattern of impaired STM and normal LTM is paralleled by a corresponding phenotype in long-term potentiation (LTP). Freely-moving Tc1 mice exhibit reduced LTP 1 h after induction but normal maintenance over days in the dentate gyrus of the hippocampal formation. Biochemical analysis revealed a reduction in membrane surface expression of the AMPAR (α-amino-3-hydroxy-5-methyl-4-propionic acid receptor) subunit GluR1 in the hippocampus of Tc1 mice, suggesting a potential mechanism for the impairment in early LTP. Our observations also provide further evidence that STM and LTM for hippocampus-dependent tasks are subserved by parallel processing streams
Congenital Factor XIII Deficiency: A Patient Report and Review of the Literature
- Author
- Publication venue
- 'SAGE Publications'
- Publication date
- Field of study
Recommended from our members
Hygroscopic properties of Amazonian biomass burning and European background HULIS and investigation of their effects on surface tension with two models linking H-TDMA to CCNC data
- Author
- Publication venue
- MĂŒnchen : European Geopyhsical Union
- Publication date
- 01/01/2010
- Field of study
HUmic-LIke Substances (HULIS) have been identified as major contributors to the organic carbon in atmospheric aerosol. The term "HULIS" is used to describe the organic material found in aerosol particles that resembles the humic organic material in rivers and sea water and in soils. In this study, two sets of filter samples from atmospheric aerosols were collected at different sites. One set of samples was collected at the K-puszta rural site in Hungary, about 80 km SE of Budapest, and a second was collected at a site in RondĂŽnia, Amazonia, Brazil, during the Large-Scale Biosphere-Atmosphere Experiment in Amazonia â Smoke Aerosols, Clouds, Rainfall and Climate (LBA-SMOCC) biomass burning season experiment. HULIS were extracted from the samples and their hygroscopic properties were studied using a Hygroscopicity Tandem Differential Mobility Analyzer (H-TDMA) at relative humidity (RH) 100%. The H-TDMA measurements were carried out at a dry diameter of 100 nm and for RH ranging from 30 to 98%. At 90% RH the HULIS samples showed diameter growth factors between 1.04 and 1.07, reaching values of 1.4 at 98% RH. The cloud nucleating properties of the two sets of aerosol samples were analysed using two types of thermal static cloud condensation nucleus counters. Two different parameterization models were applied to investigate the potential effect of HULIS surface activity, both yielding similar results. For the K-puszta winter HULIS sample, the surface tension at the point of activation was estimated to be lowered by between 34% (47.7 mN/m) and 31% (50.3 mN/m) for dry sizes between 50 and 120 nm in comparison to pure water. A moderate lowering was also observed for the entire water soluble aerosol sample, including both organic and inorganic compounds, where the surface tension was decreased by between 2% (71.2 mN/m) and 13% (63.3 mN/m)
Effect of auxin and ethylene on elongation of intact primary roots of maize (Zeamays L.)
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Strong correlation between isoprene emission and gross photosynthetic capacity during leaf phenology of the tropical tree species Hymenaea courbaril with fundamental changes in volatile organic compounds emission composition during early leaf development
- Author
- Adam K.P.
- Alonso W.R.
- Alonso W.R.
- Andreae M.O.
- Barr J.G.
- Bruggemann N.
- Burke C.
- Burke C.
- Clastre M.
- Colby S.M.
- Collins W.D.
- Croteau R.
- Croteau R.
- Fall R.
- Fischbach R.J.
- Fuentes J.D.
- Gash J.H.C.
- Geron C.
- Gershenzon J.
- Gershenzon J.
- Grinspoon J.
- Guenther A.B.
- Guenther A.B.
- Harley P.C.
- Harley P.C.
- Heide L.
- Kempf K.
- Kesselmeier J.
- Kuhn U.
- Kuhn U.
- Kuhn U.
- Kuzma J.
- Laisk A.
- Langenheim J.H.
- Langenheim J.H.
- Larcher W.
- Litvak M.E.
- Monson R.K.
- Otter L.
- Pearcy R.W.
- Phillips M.A.
- Rajaonarivony J.I.M.
- Saelim S.
- Schnitzler J.P.
- Serca D.
- Sharkey T.D.
- Sharkey T.D.
- Silver G.M.
- Teskey R.O.
- Tholl D.
- Wildermuth M.C.
- Wolfertz M.
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Global modeling of the nitrate radical (NO3) for present and pre-industrial scenarios
- Author
- A.T. Archibald
- Aliwell
- Allan
- Allan
- Andreae
- Archer-Nicholls
- Archibald
- Archibald
- Asaf
- Asaf
- Atkinson
- Atkinson
- Ball
- Bertram
- Biggs
- Biggs
- Breider
- Brown
- Brown
- Brown
- Brown
- Brown
- Brown
- C.J. Percival
- Canosa-Mas
- Carslaw
- Collins
- Crowley
- Crowley
- D.E. Shallcross
- Daele
- Derwent
- Fish
- Galmarini
- Geyer
- Geyer
- Geyer
- Granier
- Hall
- Hallquist
- Heintz
- Henze
- Houweling
- Hoyle
- Jenkin
- Kane
- Khan
- King
- Klein Goldewijk
- Kukui
- Lathiere
- Li
- M.A.H. Khan
- M.C. Cooke
- M.E. Jenkin
- Matsumoto
- Matsumoto
- McLaren
- Mellouki
- Mihelcic
- Mikaloff-Fletcher
- Monks
- Ng
- Orlando
- Ouyang
- P. Xiao
- Penkett
- Percival
- Platt
- Platt
- Platt
- Presto
- R.G. Derwent
- Ray
- S.R. Utembe
- Shallcross
- Sommariva
- Stark
- Stone
- Stutz
- Taatjes
- Tsigaridis
- Utembe
- Utembe
- van Aardenne
- Vaughan
- Vrekoussis
- W.C. Morris
- Wang
- Wang
- Watson
- Wayne
- Welz
- Wood
- Yvon
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study
Predicting the Ecosystem Consequences of Biodiversity Loss: the Biomerge Framework
- Author
- A. Balmford
- A. Hector
- A. Stephan
- A.J. Symstad
- A.J. Symstad
- A.J. Symstad
- A.J. Symstad
- A.Y. Troumbis
- A.Y. Troumbis
- B. Schmid
- B. Schmid
- B. Statzner
- B.-a. Li
- B.J. Cardinale
- B.J. Enquist
- B.J. Enquist
- B.L. Foster
- B.M. Bolker
- C. Carbone
- C. Mazancourt De
- C. Mulder
- C. Roscher
- C.G. Jones
- C.P.H. Mulder
- D. Tilman
- D. Tilman
- D. Tilman
- D.A. Heemsbergen
- D.A. Wardle
- D.A. Wardle
- D.A. Wardle
- D.A. Wardle
- D.F. Doak
- D.L. Wohl
- D.S. Wilcove
- D.U. Hooper
- D.U. Hooper
- D.U. Hooper
- D.U. Hooper
- D.W. Freckman
- E. Garnier
- E.M. Spehn
- E.M. Spehn
- E.O. Wilson
- E.S. Zavaleta
- E.S. Zavaleta
- F. SchlÀpfer
- F.S. Chapin III
- F.W. Preston
- G. Bell
- G. Sugihara
- G.A. Polis
- G.C. Daily
- G.E. Likens
- G.M. Woodwell
- H. Cyr
- H. SetÀlÀ
- H.S. Horn
- I.J. Wright
- J. Harte
- J. Kaiser
- J. LepĆĄ
- J. Lubchenco
- J. McGrady-Steed
- J. Mikola
- J. Mikola
- J. Vandermeer
- J. Vandermeer
- J. Wright
- J.B. Hughes
- J.D. Fridley
- J.E. Duffy
- J.G. Hodgson
- J.H. Brown
- J.H. Brown
- J.H. Brown
- J.J. Elser
- J.J. Stachowicz
- J.M. Chase
- J.M. Levine
- J.W. Fox
- K. Gaston
- K.A.M. Engelhardt
- K.J. Niklas
- L. Guterman
- L. ĂvreĂ„s
- M. Liiri
- M. Loreau
- M. Loreau
- M. Loreau
- M. Palmer
- M. Sankaran
- M. Solan
- M.-L. Navas
- M.A. Cavigelli
- M.C. Emmerson
- M.C. Emmerson
- M.E. Power
- M.E. Soulé
- M.G.A. Heijden Van der
- M.H. Beare
- M.O. Andreae
- M.P. Austin
- M.P. Austin
- M.P. Austin
- N.B. Grimm
- N.D. Martinez
- N.G.S. Hairston
- O. Andren
- O.E. Sala
- O.L. Petchey
- O.L. Petchey
- O.L. Petchey
- P.A. Marquet
- P.B. Adler
- P.B. Adler
- P.B. Reich
- P.H. Raven
- P.M. Vitousek
- P.R. Ehrlich
- R. Costanza
- R. Joffre
- R.D. Bardgett
- R.G. Hughes
- R.H. Groves
- R.H. MacArthur
- R.M. Callaway
- R.M. May
- R.P. McIntosh
- S. DĂaz
- S. DĂaz
- S. Lavorel
- S. Naeem
- S. Naeem
- S. Naeem
- S. Naeem
- S. Naeem
- S. Naeem
- S. Naeem
- S. Naeem
- S. Naeem
- S. Yachi
- S.P. Hubbell
- T. Fukami
- T.S. Kuhn
- V. Torsvik
- Y. Bai
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study
Plant Growth Regulators III : Gibberellins, Ethylene, Abscisic Acid, their Analogues and Inhibitors; Miscellaneous Compounds.
- Author
- A. Altman
- A. Altman
- A. Altman
- A. Altman
- A. Apelbaum
- A. Apelbaum
- A. Azpeitia
- A. Bennici
- A. Bennici
- A. Binns
- A. Blumenfeld
- A. Bouchereau
- A. Chlyah
- A. Fujiwara
- A. Gonzalez
- A. Grantz
- A. Jacoboni
- A. Kebebew
- A. Mehra
- A. Mensualisodi
- A. Perl
- A. Swiatek
- A. Yahia
- A.A. Fienberg
- A.B. Bleecker
- A.B. Das
- A.D. Savage
- A.F. Tiburcio
- A.F. Tiburcio
- A.G. Taeb
- A.G. Taylor
- A.J Khan
- A.J. Buchala
- A.K. Kukreja
- A.K. Mattoo
- A.K. Tyagi
- A.L. Engelke
- A.M Rubluo
- A.M.C. Emons
- A.N. Stepanova
- A.R. Miller
- A.R. Miller
- A.S. Bachmann
- A.V. Chadwick
- A.W. Galston
- A.W. Galston
- A.W. Galston
- B. Bisbis
- B. Bisbis
- B. Castillo
- B. Delbreil
- B. Ghosh
- B. Mcgurl
- B. Righetti
- B. Righetti
- B. Steinitz
- B. Tisserat
- B. Tisserat
- B. Tisserat
- B. Tisserat
- B. Vinocur
- B.A. Nwankwo
- B.C. Jarvis
- B.C. Jarvis
- B.J. Nairn
- B.N. Patel
- B.V. Milborrow
- C. Akimoto
- C. Bigot
- C. Brosa
- C. Hanfrey
- C. Kevers
- C. Kevers
- C. Kevers
- C. Martin
- C. Putz
- C. Stasolla
- C. Voyiatzi
- C.A. Beasley
- C.A. Lembi
- C.A. Robie
- C.A. Ryan
- C.A. Schroeder
- C.C. Dalton
- C.G. Mata
- C.H. Zhang
- C.T. Twyford
- C.W.T. Lee
- C.Y. Lu
- C.Y. Lu
- C.Y. Lu
- Ch. Moncousin
- D. Beretta
- D. Dorley
- D. Fabijan
- D. Hagege
- D. Hagege
- D. Le Rudulier
- D. Levy
- D. Mohen
- D. Poder
- D. Sankhla
- D. Sankhla
- D.A. Evans
- D.D. Songstad
- D.des Thomas
- D.des Thomas
- D.E. Nelson
- D.G. Davis
- D.I. Dunstan
- D.J. Bradley
- D.J. Brown
- D.J. James
- D.L. Smith
- D.P. Stimart
- D.R. Duncan
- D.R. Duncan
- D.R. Smith
- D.R. Walters
- D.S. Dagnino
- D.S. Koetje
- D.T. Webb
- DE
- DE
- E. Chalutz
- E. Forche
- E. Heberle-Bors
- E. Langhe De
- E. Miklashevichs
- E. Rugini
- E. Sondheimer
- E.-C. Pua
- E.C. Sisler
- E.C. Sisler
- E.C. Sisler
- E.C. Sisler
- E.G.M Meijer
- E.J. Cheong
- E.M. Beyer
- E.M. Beyer
- E.M. Beyer
- E.M. Linsmaier
- E.R.M. Wickremesinhe
- E.W. Noh
- F. Bertossi
- F. Charriere
- F. Garcia
- F. Garcia
- F. Komai
- F. Ledily
- F. Marani
- F. Meins Jr
- F. Meins Jr
- F. Meins Jr
- F. Meins Jr
- F. Pythoud
- F. Ringe
- F. Shoeb
- F. Skoog
- F.B. Abeles
- F.C. Mellor
- F.I. Rodriguez
- G. Bufler
- G. Dalessandro
- G. Felix
- G. Fridborg
- G. Fridborg
- G. Hussey
- G. Hussey
- G. Jacobs
- G. Jacobs
- G. Lakshmi Sita
- G. Morel
- G. Nemeth
- G. Vengadesan
- G. Vengadesan
- G. Wulster
- G.-L. Chi
- G.A. Vacha
- G.B. Kerbauy
- G.C. Colclasure
- G.C. Martin
- G.C. Phillips
- G.G. Laties
- G.H. Davidonis
- G.M. Moore
- G.P. Creissen
- G.S. PullmansĆ
- G.V. Novikova
- G.V. Novikova
- G.V. Novikova
- G.V.H. Jackson
- H. Gawronska
- H. Gundlach
- H. Isikawa
- H. Kamada
- H. Kohlenbach
- H. Mizukami
- H. Pal Bais
- H. Pittet
- H. Rohrig
- H. Schaller
- H. Schraudolf
- H. Soffer
- H. Suge
- H.-H. Schott
- H.C. Li
- H.E. Flores
- H.F. Taylor
- H.J. Newbury
- H.J.J. Nijkamp
- H.M. Anderson
- H.R. Kerns
- H.R. Owen
- H.S. Aldwinckle
- H.S. Ku
- H.W. Elmore
- H.Y. Rey
- I. Gavidia
- I.A. Mackenzie
- I.E Moshkov
- I.E Moshkov
- I.O. Sanders
- J. Aartrijk Van
- J. Bela
- J. Button
- J. Dai
- J. Dai
- J. Durner
- J. Guern
- J. Kochba
- J. Kochba
- J. Kochba
- J. Leon
- J. Li
- J. Li
- J. Margara
- J. Martin-Tanguy
- J. Narvaezvasquez
- J. Reinert
- J. Riov
- J. Smalle
- J.-P. Bourgin
- J.A. Jackson
- J.A. Robbins
- J.A. Simmonds
- J.B. Barroso
- J.B. Delamomarco
- J.C. Fidler
- J.D. Mauseth
- J.F. Martinez-Garcia
- J.F. Shepard
- J.J. Frett
- J.J. Kieber
- J.M. Al-Khayri
- J.M. Bonga
- J.M. Bostrack
- J.M. Canhoto
- J.M. Dunwell
- J.M. Kulpa
- J.M. Santamaria
- J.M. Widholm
- J.M. Zatyko
- J.P. Roustan
- J.P.C. Geyt Van
- J.T. Chen
- J.W. Radin
- J.W. Wang
- K. Rahbar
- K. Rajasekaran
- K. Syono
- K. Torres
- K. Tran Thanh Van
- K.E.P. Robinson
- K.F.J NovĂĄ
- K.K. Kartha
- K.K. Kartha
- K.K. Kartha
- K.K. Nanda
- K.M. Chraibi
- K.N. Pandey
- L JOHANSSON
- L. Johansson
- L. Maene
- L. Purnhauser
- L. Talmon
- L. Winata
- L.B. Torrizo
- L.W. Roberts
- L.W. Roberts
- LE
- M. Antonelli
- M. Boulay
- M. Camloh
- M. Camloh
- M. Capuana
- M. Cvikrova
- M. Delledonne
- M. Ikeda
- M. Ishitani
- M. Noma
- M. NĂșñez
- M. Panaia
- M. Tran Thanh Van
- M. Valles
- M. Valles
- M. Varga
- M. Vendrell
- M. Zeroni
- M.-T. Lepage-Degivry
- M.A. Hall
- M.A. Hartmann
- M.A. Smith
- M.A. Venis
- M.A. Weatherhead
- M.A. Weatherhead
- M.B. Jackson
- M.B. Jackson
- M.B. Jackson
- M.C. Fiore
- M.C. Mok
- M.C. Mok
- M.C. Pedroso
- M.C. Sanchez-Gras
- M.F. Coumans-Gillés
- M.G. Hahn
- M.G. Mullins
- M.H. Oh
- M.J. Constantin
- M.J. Constantin
- M.J. Hutchinson
- M.J. Muhitch
- M.J. Pan
- M.J. Thomas
- M.K. Chattopadhyay
- M.M. Khalafalla
- M.M. Laloraya
- M.P. Bridgen
- M.P. Proft De
- M.R. Suresh
- M.V. Beligni
- N. Bagni
- N. Bagni
- N. Bagni
- N. Bagni
- N. Mirjalili
- N. Palavan
- N. Sankhla
- N.L. Biddington
- N.S. Ranga Swamy
- N.S. Ranga Swamy
- O. Faure
- O. Huhtinen
- O.-L. Lau
- O.-L. Lau
- O.H. Elmer
- O.L. Gamborg
- O.L. Gamborg
- O.L. Gamborg
- O.M. Heide
- O.M. Heide
- O.P. Jones
- O.P. Jones
- P. Aducci
- P. Albersheim
- P. Gavinlertvatana
- P. Krogstrup
- P. Lambe
- P. Rosati
- P. Sauerbrey
- P. SPIEGEL-Roy
- P. Spiegel-Roy
- P. Vernieri
- P.B. Goodwin
- P.F. Wareing
- P.G. Alderson
- P.G. Bartels
- P.H. Bressan
- P.H. Jerie
- P.J. Yates
- P.J.J. Hooykaas
- P.K. Busk
- P.M. Bradley
- P.N. Walker
- P.P. Kumar
- P.R. Fobert
- P.R. Johnson
- P.S. Rao
- P.T. Evans
- P.V. Ammirato
- P.V. Ammirato
- P.V. Ammirato
- P.W. Brian
- P.W.J. Taylor
- PH. Boxus
- PH. Boxus
- PH. Druart
- PH. Druart
- Q. Chao
- R. Aloni
- R. Ernst
- R. Feirer
- R. Friedman
- R. Friedman
- R. Jona
- R. Kaur-Sawhney
- R. Keller
- R. Moore
- R. Phillips
- R. Phillips
- R. Puschmann
- R. Scorza
- R. Scorza
- R. Stuart
- R. Theiler
- R. Tizio
- R.A. Fletcher
- R.C. Shoemaker
- R.D. Rice
- R.D. Slocum
- R.E. Litz
- R.E. Young
- R.F. Elliott
- R.G.S. Brown
- R.H. Wallace
- R.J. Eilers
- R.J. Gautheret
- R.J. Gautheret
- R.K. Kakkar
- R.L. Jarret
- R.L. Malmberg
- R.L. Scholl
- R.M. Behki
- R.N. Konar
- R.P. Feirer
- R.R. Henke
- R.S. Sangwan
- R.W. Zobel
- S. Bajaj
- S. Bajaj
- S. Biondi
- S. Biondi
- S. Fernandez
- S. Fujioka
- S. Hiraga
- S. Jelaska
- S. Mukund
- S. Pennazio
- S. Takayama
- S. Tanimoto
- S. Yanagisawa
- S.-C. Cho
- S.B. Ryu
- S.C. Fernando
- S.C. Minocha
- S.D. Clouse
- S.F. Yang
- S.I. Gibson
- S.J. Nissen
- S.J. Nissen
- S.J. Vine
- S.K. Pattnaik
- S.K. Pillai
- S.K. Rijhwani
- S.K. Srivastava
- S.M. McCulloch
- S.P. Burg
- S.T. Fujioka
- S.T.C. Wright
- S.W. Adkins
- S.Y. Byun
- S.Y. Wang
- T. Berglund
- T. Fujimura
- T. Hatanaka
- T. Hisamatsu
- T. Ishizaki
- T. Iwasaki
- T. Langowska
- T. Murashige
- T. Murashige
- T. Nomura
- T.-Y. Cheng
- T.A. McKeon
- T.A. Smith
- T.A. Smith
- T.A. Smith
- T.A. Thorpe
- T.A. Thorpe
- T.A.G. Larue
- T.D. Davis
- T.D. Ghazi
- T.G. Guevin
- T.J. Huxter
- T.J. Huxter
- T.M. Lee
- T.M. Lee
- T.S. Hooker
- T.S. Kochhar
- T.T. Hahn
- T.T. Sekioka
- TH. Gaspar
- Th. GASPAR
- U. Heinzmann
- U. Heinzmann
- U. Rao
- V. Alchanatis
- V. Babic
- V. Piironen
- V. Vasil
- V.A. Bapat
- V.I. Oshmarina
- V.K. Anand
- V.K. Gautam
- V.L. Dodeman
- V.M. Jimenez
- V.M. Jimenez
- VON
- W. Barz
- W. Greef De
- W. Horn
- W. Rademacher
- W. Tang
- W.A. Andreae
- W.Abou-Mandour A.A. Hartung
- W.B. McGlasson
- W.C. Anderson
- W.C. Chang
- W.C. Chang
- W.C. Wilson
- W.D. Lane
- W.D. Lane
- W.J. Blackmon
- W.J. Blackmon
- W.K. Coleman
- W.K. Coleman
- W.K. Coleman
- W.K. Coleman
- W.S. York
- Y. Heimer
- Y. Hu
- Y. Kato
- Y. Sahoo
- Y. Shoyama
- Y. Tokuji
- Y. Yukimune
- Y.-B. Yu
- Y.H. Yang
- Y.W. Kim
- Y.Y. Ford
- Y.Y. Leshem
- Z. Even-Chen
- Z. Kefu
- Z.H. He
- Z.J. Guo
- Z.S. Wochok
- Z.S. Wochok
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2007
- Field of study
Literature
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2008
- Field of study
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- Publication venue
- 'Wiley'
- Publication date
- Field of study