249 research outputs found
Translational dynamics effects on the non-local correlations between two atoms
A pair of atoms interacting successively with the field of the same cavity
and exchanging a single photon, leave the cavity in an entangled state of
Einstein-Podolsky-Rosen (EPR) type (see, for example, [S.J.D. Phoenix, and S.M.
Barnett, J. Mod. Opt. \textbf{40} (1993) 979]). By implementing the model with
the translational degrees of freedom, we show in this letter that the
entanglement with the translational atomic variables can lead, under
appropriate conditions, towards the separability of the internal variables of
the two atoms. This implies that the translational dynamics can lead, in some
cases, to difficulties in observing the Bell's inequality violation for massive
particles.Comment: 5 pages, 1 figur
On the observability of Bell's inequality violation in the optical Stern-Gerlach model
Using the optical Stern-Gerlach model, we have recently shown that the
non-local correlations between the internal variables of two atoms that
successively interact with the field of an ideal cavity in proximity of a nodal
region are affected by the atomic translational dynamics. As a consequence,
there can be some difficulties in observing violation of the Bell's inequality
for the atomic internal variables. These difficulties persist even if the atoms
travel an antinodal region, except when the spatial wave packets are exactly
centered in an antinodal point.Comment: 5 pages, 1 figure, submitted to European Physical Journal
Adventures of clinical psychology
Clinical psychology strives to fully grasp the person in his totality and in his individuality, helping him adequately address his own deep internal suffering and discomfort, social uneasiness, and harmonize his own needs, desires and, attachments [...]
Embracing the complexity of neurodevelopmental disorders
Neurodevelopmental disorders are a group of neuropsychiatric diseases that affect the developing brain due to a complex interaction between genetic and environmental factors [...]
The non dissipative damping of the Rabi oscillations as a "which-path" information
Rabi oscillations may be viewed as an interference phenomenon due to a
coherent superposition of different quantum paths, like in the Young's two-slit
experiment. The inclusion of the atomic external variables causes a non
dissipative damping of the Rabi oscillations. More generally, the atomic
translational dynamics induces damping in the correlation functions which
describe non classical behaviors of the field and internal atomic variables,
leading to the separability of these two subsystems. We discuss on the
possibility of interpreting this intrinsic decoherence as a "which-way"
information effect and we apply to this case a quantitative analysis of the
complementarity relation as introduced by Englert [Phys. Rev. Lett.
\textbf{77}, 2154 (1996)].Comment: 5 pages, 2 figure
Survey of the Beneficial Flowers Available in Coimbatore District, Tamil Nadu, India
The flora of an area is considered a vital part of the environment, regulating the prosperity of the biosphere and people's health. It is highly suggested that the proper utilization of plant resources in each part of a country has been useful in conserving the availability and productivity of the flora. The present investigation aimed to evaluate the survey of the beneficial flowers available in Coimbatore District, Tamil Nadu, India, from December 2019 to February 2020. The survey studies were divided into four different zones in Coimbatore District: Perur, Ganapathy, Thudiyalur, and Periyanaickenpalayam, respectively. The survey resulted in the collection of 40 plant species belonging to 38 genera, dispersed over 25 families of flowering plants / angiosperms. The dominant families were Apocynaceae and Oleaceae when compared to other families. This study reveals that species such as Calotropis gigantean, Chrysanthemum morifolium, Couroupita guianensis, Nerium oleander, Nyctanthes arbortristis, Nelumbo nucifera, and Tabernaemontana divaricata were used as ritual flowers. The beneficial flowers showed a maximum for ornamental flowers (43 percent), followed by ritual flowers (35 percent), medicinal flowers (15 percent), and cooking flowers (7 percent), respectively. The highest blooming of the flowers (14.89 percent) occurred in March, and the lowest in November and December. Flowers were documented as having economic value, with the highest rate in Rosa sp., and Jasminum sp., which were used as ornamental, medicinal, and cosmetic preparations as valuable resources. Scientific key information on taxonomy and technical approaches to beneficial flowers was analyzed. Flowers play a vital role in human life from birth to death and are used in all auspicious events in India, especially in daily prayers in temples and Indian households
The new covid-19 related psychological distress pandemic
Although a few years have passed since the beginning of the COVID-19 pandemic, a large body of scientific literature is already present on the impact that the worldwide spread of the virus has had on people's quality of life [...]
Thioflavin T triggers \u3b2 amyloid peptide (1-40) fibrils formation.
Introduction
A general characteristic of aggregation is the multiple interaction and cross-feedback among distinct mechanisms
occurring at different hierarchical levels. The comprehension of the different species interconversion during aggregation
is very important since emerging evidences indicate intermediate oligomeric aggregates as primary toxic species. In this
context, A\u3b2 amyloid peptide provides a challenging model for studying aggregation phenomena both for the complexity
of its association process and for the direct implications in Alzheimer\u2019s Disease. Aggregates growth conditions strongly
affect the final morphology, the fibrillar molecular structure as well as the aggregation pathway which is characterized
by the occurrence of multiple transient species.
Methods
The fluorescent dye Thioflavin T (ThT) is widely used to detect amyloid deposits and it is often used in situ to study
aggregation kinetics, under the hypothesis that its presence does not affect the aggregation processes under study. Here
we present an experimental study on A\u3b2(1-40) peptide fibrillation kinetics at pH 7.4. In the observed conditions, A\u3b2(1-
40) undergoes aggregation only if Thioflavin T is present in solution. This phenomenon was analyzed as a function of
temperature, ThT and peptide concentrations in order to explore the underlying fibrillation mechanism. Light scattering,
ThT fluorescence emission, two photon excitation fluorescence microscopy, were used in a kinetic fashion to highlight
different sides and critical phases of the aggregation pathway. Circular Dichroism and FTIR measurements are used to
characterize secondary structure of the aggregates.
Results
The selected approach gives detailed information on the time evolution of A\u3b2(1-40) fibrillation process highlighting
structural changes at molecular level, different aggregate species growth and their morphologies. Our data show that
A\u3b2(1-40) fibrillation process occurs only in the presence of ThT and that the observed aggregation involves at least
three different aggregation mechanisms acting in competition. In the first step, small oligomers, which bind ThT, are
formed via non nucleated polymerization mechanism and represent an activated state for following fibrils growth. This
process appear to be a rate limiting step for two distinct fibril nucleation mechanisms probably affected by an high
degree of spatial heterogeneity.
Conclusions
We demonstrated that in the selected experimental conditions ThT triggers the A\u3b2(1 1240) fibrillation process (D\u2019Amico
et. al 2012). Sterical and chemical properties of ThT molecule may modulate the peptide conformation, with similar
mechanisms to the ones that usually drive the binding of this dye to already formed amyloids. So, the presence of ThT
in solution may change the thermodynamic equilibrium trapping specificmore ordered conformations prone to
supramolecular assembly
Protein materials as sustainable non- and minimally invasive strategies for biomedical applications
Protein-based materials have found applications in a wide range of biomedical fields because of their biocompatibility, biodegradability and great versatility. Materials of different physical forms including particles, hydrogels, films, fibers and microneedles have been fabricated e.g. as carriers for drug delivery, factors to promote wound healing and as structural support for the generation of new tissue. This review aims at providing an overview of the current scientific knowledge on protein-based materials, and selected preclinical and clinical studies will be reviewed in depth as examples of the latest progress within the field of protein-based materials, specifically focusing on non- and minimally invasive strategies mainly for topical application
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