Post-functionalized iridium Zr-MOF as a promising recycle catalyst for the hydrogenation of aromatics

[EN] The multifunctional heterogeneous catalyst iridium–Zr-based MOF is able to effectively catalyze the hydrogenation of aromatic compounds in high yields under mild conditions. The catalyst was found to be highly active and reusable, giving similar reactivity and selectivity after at least five catalytic uses.We thank the MINECO of Spain (project MAT2011-29020-C02-02), Consolider-Ingenio 2010-(CSD-0050-MULTICAT). for financial support. A.M.R.A. thanks MINECO for the FPI program.Rasero Almansa, AM.; Corma Canós, A.; Iglesias, M.; Sánchez Alonso, F. (2014). Post-functionalized iridium Zr-MOF as a promising recycle catalyst for the hydrogenation of aromatics. Green Chemistry. 16(7):3522-3527. https://doi.org/10.1039/c4gc00581cS3522352716

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Bifunctional iridium-(2-aminoterephthalate)-Zr-MOF chemoselective catalyst for the synthesis of secondary amines one-pot three-step cascade reaction

[EN] A simple and efficient method for the synthesis of N-alkyl amines via a cascade reaction (hydrogenation + reductive amination) using a new recyclable hybrid catalyst that combines the catalytic power of transition metal complexes with the architecture of metal organic frameworks (MOFs). (C) 2012 Elsevier Inc. All rights reserved.We thank CONSOLIDER-INGENIO 2010-(CSD-0050-MULTICAT) and the MINECO of Spain (Project MAT2011-29020-C02-02) for financial supportPintado Sierra, M.; Rasero Almansa, AM.; Corma Canós, A.; Iglesias, M.; Sánchez, F. (2013). Bifunctional iridium-(2-aminoterephthalate)-Zr-MOF chemoselective catalyst for the synthesis of secondary amines one-pot three-step cascade reaction. Journal of Catalysis. 299:137-145. https://doi.org/10.1016/j.jcat.2012.12.004S13714529

Unveiling the potential of a covalent triazine framework based on [1]benzothieno[3,2-b][1]benzothiophene (DPhBTBT-CTF) as a metal-free heterogeneous photocatalyst

The development of photocatalysts that are effective in different organic processes is a topic of great interest to researchers in materials chemistry. Herein, we report the design and synthesis of a new covalent triazine framework (CTF) built by acid-catalyzed trimerization of 4,4′-(benzo[b]benzo[4,5]thieno[2,3-d]thiophene-2,7-diyl)dibenzonitrile activated by microwaves that generates a new organic polymer, DPhBTBT-CTF. This CTF exhibits visible-light absorption due to the electron-donating BTBT units and the extended π-conjugated framework with the electron-acceptor triazine node and proves to be an efficient and versatile metal-free heterogeneous photocatalyst for different organic processes such as selective oxidations of both sulfides and benzyl alcohols to sulfoxides and benzaldehydes, respectively or the oxidative bromination of electron rich aromatic compounds. Moreover, two different proof of concept reactions were tested: the Diels-Alder cycloaddition and the hydroxylation of boronic acids. Heterogeneity studies confirmed that this photocatalyst can be recycled without significant loss of selectivity, and also some mechanistic tests suggested the preferred oxidation pathway.The authors acknowledge the grants PID2020-112590GB-C22 and PID2020-112590GB-C21 funded by MCIN/AEI/ 10.13039/501100011033. The authors also acknowledge Dr M Luisa Ferrer and Laura González for the electrochemical analysi

Phenyl Extended Naphthalene-Based Covalent Triazine Frameworks as Versatile Metal-Free Heterogeneous Photocatalysts

Two new covalent triazines frameworks (CTFs) containing phenyl extended naphthalene units (with and without methoxy groups in the naphthalene core) are prepared by thermal and microwave activation. Both procedures yield similar chemical structures combining triazine acceptor units with donor aromatic groups, but they generate some differences in the morphology, structural organization, CO adsorption capacity, and thermal and optical properties. Besides, the methoxy groups of the naphthalene core have also influence in some of these properties. The resulting phenyl extended naphthalene CTFs are efficiently utilized as metal-free heterogeneous photocatalyst for the selective aerobic oxidation of sulfides and the dehydrogenative cross-coupling reactions under visible-light irradiation, showing a high chemical stability.The authors acknowledge grants MAT2017-82288-C2-2-P and PID2020-112590GB-C22 funded by MCIN/AEI/10.13039/501100011033 and by“ERDF A way of making Europe”. A.V.G. thanks Ministerio de Universidades for FPU17/0346

Convergence of Gaussian-beam Modes in Corrugated Conical Horns

Gaussian beam-mode expansion with only the fundamental mode does not work properly when the angular region of interest is wide. It is necessary to use higher-order mode for the expansion. A study of the convergence of these higher order modes is presented for the case of a corrugated conical horn. Conclusions about the number of modes necessary for good accuracy are given