Mental Fatigue Affects Visual Selective Attention

Mental fatigue is a form of fatigue, induced by continuous task performance. Mentally fatigued people often report having a hard time keeping their attention focussed and being easily distracted. In this study, we examined the relation between mental fatigue, as induced by time on task, and attention-related changes in event-related potentials (ERPs). EEG, reaction times and response accuracies were obtained from 17 healthy volunteers during two hours of task performance on an adapted Eriksen flanker task. In this task, the size of targets and flankers was manipulated to discern neuronal processes that are related to processing of relevant information from processes related to the processing of irrelevant information. The ERP data showed that effects induced by target size manipulation were not affected by time on task, while an initial effect of flanker size manipulation decreased gradually with increasing time on task. We conclude that attention was affected by mental fatigue, in the form of a decrease in the ability to suppress irrelevant information. In behavioural results, this was reflected by a tendency of participants to increasingly base their response decision on irrelevant information, resulting in decreased response accuracies

Is Categorization in Visual Working Memory a Way to Reduce Mental Effort? A Pupillometry Study

Recent studies on visual working memory (VWM) have shown that visual information can be stored in VWM as continuous (e.g., a specific shade of red) as well as categorical representations (e.g., the general category red). It has been widely assumed, yet never directly tested, that continuous representations require more VWM mental effort than categorical representations; given limited VWM capacity, this would mean that fewer continuous, as compared to categorical, representations can be maintained simultaneously. We tested this assumption by measuring pupil size, as a proxy for mental effort, in a delayed estimation task. Participants memorized one to four ambiguous (boundaries between adjacent color categories) or prototypical colors to encourage continuous or categorical representations, respectively; after a delay, a probe indicated the location of the to‐be‐reported color. We found that, for memory load 1, pupil size was larger while maintaining ambiguous as compared to prototypical colors, but without any difference in memory precision; this suggests that participants relied on an effortful continuous representation to maintain a single ambiguous color, thus resulting in pupil dilation while preserving precision. Strikingly, this effect gradually inverted, such that for memory load 4, pupil size was smaller while maintaining ambiguous and prototypical colors, but memory precision was now substantially reduced for ambiguous colors; this suggests that with increased memory load participants increasingly relied on categorical representations for ambiguous colors (which are by definition a poor fit to any category). Taken together, our results suggest that continuous representations are more effortful than categorical representations and that very few continuous representations (perhaps only one) can be maintained simultaneously

Concurrent guidance of attention by multiple working memory items:Behavioral and computational evidence

During visual search, task-relevant representations in visual working memory (VWM), known as attentional templates, are assumed to guide attention. A current debate concerns whether only one (Single-Item-Template hypothesis; SIT) or multiple (Multiple-Item-Template hypothesis; MIT) items can serve as attentional templates simultaneously. The current study was designed to test these two hypotheses. Participants memorized two colors, prior to a visual-search task in which the target and the distractor could match or not match the colors held in VWM. Robust attentional guidance was observed when one of the memory colors was presented as the target (reduced response times (RTs) on target-match trials) or the distractor (increased RTs on distractor-match trials). We constructed two drift-diffusion models that implemented the MIT and SIT hypotheses, which are similar in their predictions about overall RTs, but differ in their predictions about RTs on individual trials. Critically, simulated RT distributions and error rates revealed a better match of the MIT hypothesis to the observed data than the SIT hypothesis. Taken together, our findings provide behavioral and computational evidence for the concurrent guidance of attention by multiple items in VWM

Neural correlates associated with successful working memory performance in older adults as revealed by spatial ICA

To investigate which neural correlates are associated with successful working memory performance, fMRI was recorded in healthy younger and older adults during performance on an n-back task with varying task demands. To identify functional networks supporting working memory processes, we used independent component analysis (ICA) decomposition of the fMRI data. Compared to younger adults, older adults showed a larger neural (BOLD) response in the more complex (2-back) than in the baseline (0-back) task condition, in the ventral lateral prefrontal cortex (VLPFC) and in the right fronto-parietal network (FPN). Our results indicated that a higher BOLD response in the VLPFC was associated with increased performance accuracy in older adults, in the more complex task condition. This 'BOLD-performance' relationship suggests that the neural correlates linked with successful performance in the older adults are related to specific working memory processes present in the complex but not in the baseline task condition [corrected].Furthermore, the selective presence of this relationship in older but not in younger adults suggests that increased neural activity in the VLPFC serves a compensatory role in the aging brain which benefits task performance in the elderly

Correction: Neural Correlates Associated with Successful Working Memory Performance in Older Adults as Revealed by Spatial ICA

There are errors in the fourth and fifth sentences of the Abstract. The correct sentences are: Our results indicated that a higher BOLD response in the VLPFC was associated with increased performance accuracy in older adults, in the more complex task condition. This ‘BOLD-performance’ relationship suggests that the neural correlates linked with successful performance in the older adults are related to specific working memory processes present in the complex but not in the baseline task condition.There are errors in the second and third sentences of the second paragraph of the “Independent component analysis (ICA)” portion of the “fMRI image analysis” subsection of the Materials and Methods. The correct sentences are: The GLM design matrix was based on the task events (onsets), as well as the movement parameters derived from the realignment step and their first derivatives and a high pass filter of 230 seconds, implemented using a discrete cosine transform (DCT) set. The task events were convolved with three basis functions of the hemodynamic response function (HRF): the canonical HRF, its time derivative and its dispersion derivative.There are multiple errors throughout the “Performance and age” section of the Results. The correct text is: Older adults had a mean accuracy cost of.23 (SD = .12) and a mean speed cost of.47 (.19). Younger adults had a mean accuracy cost of.08 (.04) and a mean speed cost of.31 (.18). Coefficients for the main effects of age on accuracy and speed cost were based on the regression model assessing the effects of age and/or BOLD load effect in the VLPFC component. Older adults had a higher accuracy cost (β age = .147, t(74) = 7.08, p < .0005; R2 = .419, F(3,74) = 18.8, p < .0005) and speed cost (β age = .167, t(74) = 4.01, p < .0005; R2 = .215, F(3,74) = 6.5, p < .0005) than younger adults. Additional regression models, performed in each load condition, revealed that older adults had lower accuracy scores in the 2-back load than younger adults (β age = −.129, t(74) = −6.47, p < .0005; R2 = .414, F(3,74) = 16.7, p < .0005). Furthermore, older adults were slower than younger adults in both load conditions (0-back: β age = 115.32, t(74) = 9.83, p < .0005; R2 = .581, F(3,74) = 32.9, p < .0005 and 2-back: β age = 249.01, t(74) = 9.61, p < .0005; R2 = .569, F(3,74) = 31.3, p < .0005; see Table 2).There are multiple errors throughout the “Components of interest: Age and BOLD load effect” section of the Results. The correct text is: The main repeated measure ANOVA on the BOLD load effects observed in the eight ICs associated with working memory processes, showed a general interaction between age and BOLD load effect (F(7,511) = 3.1, p = .007). To identify which of these 8 ICs showed an age-related BOLD load effect, additional post-hoc two sample t-tests were performed. These tests revealed that the difference in BOLD activation between the 2-back and the 0-back load condition was larger for older than younger adults in 3 ICs. Namely, the ICs containing mainly the VLPFC (t(73) = 1.9, p = .061), the right FPN (t(73) = 2.2, p = .035) and the left FPN (t(73) = 4, p < .0005).After identifying these 3 ICs, we subsequently performed a one-sample t-test in younger and older adults, separately. The purpose of these tests was to investigate whether the BOLD activation in each of the 3 selected ICs differed significantly between the 0-back and the 2-back load condition within each age-group. The one-sample t-test was significant in all 3 ICs, for younger (VLPFC: t(37) = 6.5, p< .0005; right FPN: t(37) = 3, p = .005 and left FPN: t(37) = -4.1, p< .0005) and older adults (VLPFC (t(36) = 9.8, p< .0005), the right FPN (t(36) = 6, p< .0005 and the left FPN (t(36) = -1.7, p = .093). For all participants, the BOLD activation in the right FPN and the VLPFC increased with task load. However, the BOLD activation of the left FPN was negatively modulated by the task, as revealed by the negative beta-weights and the positive spatial map of this component (see Fig 2B and Fig 3). In young adults, the BOLD activation in the left FPN became more negative with increasing task demands. To determine whether age modulated the BOLD signal in these 3 ICs of interest in the 0-back, in the 2-back or in both load conditions, subsequent post-hoc independent two sample t-tests were performed. These tests showed that compared to younger adults, older adults had a higher BOLD activation in the VLPFC (t(73) = 3, p = .006) and the right FPN (t(73) = 2.4, p = .020), in the 2-back load condition. In the 0-back load condition, younger and older adults showed similar BOLD activation in the VLPFC and the right FPN. On the other hand, older adults had a more negative BOLD response in the left FPN than younger adults, in the 0-back load condition (t(73) = 4.5, p < .0005). Younger and older adults had comparable BOLD load effect in the other working memory related ICs

Effects of cue validity on attentional selection

Visual attention can be allocated to locations or objects, leading to enhanced processing of information at the specific location (space-based effects) or specific object (object-based effects). Previous studies have observed object-based effects to be smaller and less robust than space-based effects, with large individual differences in their temporal occurrence. Studies on space- and object-based effects are often based on a two-rectangle paradigm in which targets appear at cued locations more often than uncued locations. It is, however, unclear whether and how the target's spatial probability affects the temporal occurrence of these effects. In three experiments with different cue validities (80%, 50% and 33%), we systematically changed the interval between the cue and the target from 50 to 600 ms. On a group level and for individuals, we examined how cue validity affects the occurrence of object- and space-based effects. We observed that the magnitude and the prevalence of space-based effects heavily decreased with reduced cue validity. Object-based effects became even more sparse and turned increasingly negative with decreasing cue validity, representing a different-object rather than a same-object advantage. These findings indicate that changes in cue-validity affect both space- and object-based effects, but it does not account for the low prevalence and magnitude of object-based effects

Dynamic modulation of neural feedback processing and attention during spatial probabilistic learning

Learned stimulus-reward associations can modulate behavior and the underlying neural processing of information. We investigated the cascade of these neurocognitive mechanisms involved in the learning of spatial stimulus-reward associations. Using electroencephalogram recordings while participants performed a probabilistic spatial reward learning task, we observed that the feedback-related negativity component was more negative in response to loss feedback compared to gain feedback but showed no modulation by learning. The late positive component became larger in response to losses as the learning set progressed but smaller in response to gains. In addition, feedback-locked alpha frequency oscillations measured over occipital sites were predictive of N2pc amplitudes—a marker of spatial attention orienting—observed on the next trial. This relationship was found to become stronger with learning set progression. Taken together, we elucidated neurocognitive dynamics underlying feedback processing during spatial reward learning, and the subsequent effects of these learned spatial stimulus-reward associations on spatial attention

Dynamics in typewriting performance reflect mental fatigue during real-life office work

Mental fatigue has repeatedly been associated with decline in task performance in controlled situations, such as the lab, and in less controlled settings, such as the working environment. Given that a large number of factors can influence the course of mental fatigue, it is challenging to objectively and unobtrusively monitor mental fatigue on the work floor. We aimed to provide a proof of principle of a method to monitor mental fatigue in an uncontrolled office environment, and to study how typewriting dynamics change over different time-scales (i.e., time-on-task, time-of-day, day-of-week). To investigate this, typewriting performance of university employees was recorded for 6 consecutive weeks, allowing not only to examine performance speed, but also providing a natural setting to study error correction. We show that markers derived from typewriting are susceptible to changes in behavior related to mental fatigue. In the morning, workers first maintain typing speed during prolonged task performance, which resulted in an increased number of typing errors they had to correct. During the day, they seemed to readjust this strategy, reflected in a decline in both typing speed and accuracy. Additionally, we found that on Mondays and Fridays, workers adopted a strategy that favored typing speed, while on the other days of the week typing accuracy was higher. Although workers are allowed to take breaks, mental fatigue builds up during the day. Day-to-day patterns show no increase in mental fatigue over days, indicating that office workers are able to recover from work-related demands after a working day

Second Chances in Learning:Does a Resit Prospect Lower Study-Time Investments on a First Test?

Previous studies have shown that the prospect of a resit opportunity lowers hypothetical study-time investments for a first exam, as compared to a single-chance exam (i.e., the resit effect). The present paper describes a first experiment in which we aimed to generalize this effect from hypothetical study-time investments to a learning task allowing for the optimization of actual study-time investments while participants studied pairs of pseudowords for a subsequent multiple-choice test, given either a single chance or two chances to pass. Against our expectations, the results of the experiment showed no resit effect for the amount of actual time participants spent studying the materials in the experimental learning task. To better allow for the optimization of study-time investments, the learning task was adapted for a second experiment to include an indication of passing probability. These results, however, also did not show a resit effect. A third experiment addressed whether it was the investment of actual time that led to this absence of a resit effect with the learning task. The results suggested, however, that it was most likely the lack of a priori deliberation that caused this absence of the effect. Taken together with findings from a fourth questionnaire study showing that students seem to take a resit prospect into account by indicating they would have studied more for an exam if the option to resit would not have been available, these findings lead us to argue that a resit prospect may primarily affect advance study-time allocation decisions

Other road users’ adaptations to increase safety in response to older drivers’ behaviour

Changes in physical and cognitive abilities not only challenge the driving ability of older adults, in some situations age-related changes in driving behaviour require other road users to adapt their behaviour to maintain a safe traffic situation. In this study, we aimed to map age-related differences in driving behaviour and assess the impact on other road users. A group younger and a group older adults drove four different routes containing challenging situations (e.g., merging into motorway traffic) in a driving simulator while measures of driving behaviour were collected. Other road users’ deceleration responses to the driver's behaviour were also collected as a measure of behavioural adaptation. Our results showed similar driving performance between young and older drivers when task complexity was low, but reduced performance in older drivers when tasks requirements increased. Lower driving speed and longer waiting times that were observed in older drivers can be interpreted as compensatory behaviour aimed at creating more time to lower task requirements. Crucially, in a non-time critical situation this compensatory behaviour was found to be successful, however in a time-critical situation (merging onto a motorway) this strategy had negative side effects because other road users had to decelerate in order to keep a safe distance. Our results show the importance of anticipation and adaptation by other road users for the success of older driver's strategies and traffic safety