Signals of CP Violation Beyond the MSSM in Higgs and Flavor Physics

We study an extension of the Higgs sector of the Minimal Supersymmetric Standard Model (MSSM), considering the effects of new degrees of freedom at the TeV scale, and allowing for sources of CP violation beyond the MSSM (BMSSM). We analyze the impact of the BMSSM sources of CP violation on the Higgs collider phenomenology and on low energy flavor and CP violating observables. We identify distinct Higgs collider signatures that cannot be realized, either in the case without CP violating phases or in the CP violating MSSM, and investigate the prospects to probe them at the Tevatron and the LHC. The most striking benchmark scenario has three neutral Higgs bosons that all decay dominantly into W boson pairs and that are well within the reach of the 7 TeV LHC run. On the other hand, we also present scenarios with three Higgs bosons that have masses M_Hi > 150 GeV and decay dominantly into b bbar. Such scenarios are much more challenging to probe and can even lie completely outside the reach of the 7 TeV LHC run. We explore complementary scenarios with standard MSSM Higgs signals that allow to accommodate a sizable B_s mixing phase as indicated by D0, as well as the excess in B_s --> mu+ mu- candidates recently reported by CDF. We find that, in contrast to the MSSM, a minimal flavor violating soft sector is sufficient to generate significant corrections to CP violating observables in meson mixing, compatible with EDM constraints. In particular, a sizable B_s mixing phase, S_psiphi < 0.4, can be achieved for specific regions of parameter space. Such a large B_s mixing phase would unambiguously imply a sizable suppression of S_psiKs with respect to the SM prediction and a BR(B_s --> mu+ mu-) close to the 95% C.L. upper bound reported by CDF.Comment: 58 pages, 15 figures, 2 tables, v2 matches published versio

Heterogeneities along the 2009 L’Aquila normal fault inferred by the b-value distribution

In this study we map the distribution of the b-value of the Gutenberg-Richter law—as well as complementary seismicity parameters—along the fault responsible for the 2009 MW 6.1 L'Aquila earthquake. We perform the calculations for two independent aftershock sub-catalogs, before and after a stable magnitude of completeness is reached. We find a substantial spatial variability of the b-values, which range from 0.6 to 1.3 over the fault plane. The comparison between the spatial distribution of the b-values and the main-shock slip pattern shows that the largest slip occurs in normal-to-high b-values portion of the fault plane, while low b-value is observed close to the main-shock nucleation. No substantial differences are found in the b-value computed before and after the main-shock struck in the small region of the fault plane populated by foreshocks

Automated detection of lung nodules in low-dose computed tomography

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector computed-tomography (CT) images has been developed in the framework of the MAGIC-5 Italian project. One of the main goals of this project is to build a distributed database of lung CT scans in order to enable automated image analysis through a data and cpu GRID infrastructure. The basic modules of our lung-CAD system, consisting in a 3D dot-enhancement filter for nodule detection and a neural classifier for false-positive finding reduction, are described. The system was designed and tested for both internal and sub-pleural nodules. The database used in this study consists of 17 low-dose CT scans reconstructed with thin slice thickness (~300 slices/scan). The preliminary results are shown in terms of the FROC analysis reporting a good sensitivity (85% range) for both internal and sub-pleural nodules at an acceptable level of false positive findings (1-9 FP/scan); the sensitivity value remains very high (75% range) even at 1-6 FP/scanComment: 4 pages, 2 figures: Proceedings of the Computer Assisted Radiology and Surgery, 21th International Congress and Exhibition, Berlin, Volume 2, Supplement 1, June 2007, pp 357-35

Flank sliding: A valve and a sentinel for paroxysmal eruptions and magma ascent at Mount Etna, Italy

Rising magma, dike intrusions, and flank collapse are observed at many volcanoes worldwide, but how they interact is still poorly documented. Extensive synthetic aperture radar interferometry and continuous global positioning system observations captured a sharp dike intrusion at Mount Etna, Italy, during the 2018 paroxysm that triggered a vigorous seaward sliding of the eastern flank connected with brittle failure and deep magmatic resourcing. We propose a feedback process between flank acceleration and magma intrusion that derives from the interaction between the long- and short-term deformation of the volcano. The flank sliding acts as a valve that modulates the emplacement and eruption of magma within the shallow system. Rapid flank acceleration could potentially evolve into sudden collapses and seismic release at shallow depth. In turn, flank slip events could act as a sentinel for changes in magma depth and paroxysmal eruptions at Mount Etna

The role of erythropoietin stimulating agents in anemic patients with heart failure: solved and unresolved questions.

Anemia is a common finding in congestive heart failure (CHF) and is associated with an increased mortality and morbidity. Several conditions can cause depression of erythroid progenitor cells: reduction of iron absorption and reuptake, decreased bone marrow activity, reduced endogenous erythropoietin production, and chronic inflammatory state. Anemia's etiology in CHF is complex and partially understood; it involves several systems including impaired hemodynamic condition, reduced kidney and bone perfusion, increased inflammatory activity, and neurohormonal overdrive. The use of erythropoiesis stimulating agents (ESAs) such as erythropoietin and its derivatives is recently debated; the last interventional trial seems to demonstrate a neutral or negative effect in the active arm with darbepoetin treatment. The current data is opposite to many single blind studies and previous meta-analysis showing an improvement in quality of life, New York Heart Association class, and exercise tolerance using ESA therapy. These contrasting data raise several concerns regarding the target of hemoglobin levels needing intervention, the exact anemia classification and categorization, and the standardization of hematocrit cutoffs. Some cardiac and systemic conditions (ie, hypertension, atrial fibrillation, prothrombotic status) may predispose to adverse events, and ESA administration should be avoided. To prevent the negative effects, high-dosage and chronic administration should be avoided. Clarification of these items could probably identify patients that may benefit from additional iron or ESA treatment. In this review, we discuss the interventional trials made in anemic heart failure patients, the underlying mechanism of anemia in CHF, and the potential role of ESA in this setting

Factorizing the time evolution operator

There is a widespread belief in the quantum physical community, and in textbooks used to teach Quantum Mechanics, that it is a difficult task to apply the time evolution operator Exp{-itH/h} on an initial wave function. That is to say, because the hamiltonian operator generally is the sum of two operators, then it is a difficult task to apply the time evolution operator on an initial wave function f(x,0), for it implies to apply terms operators like (a+b)^n. A possible solution of this problem is to factorize the time evolution operator and then apply successively the individual exponential operator on the initial wave function. However, the exponential operator does not directly factorize, i. e. Exp{a+b} is not equal to Exp{a}Exp{b}. In this work we present a useful procedure for factorizing the time evolution operator when the argument of the exponential is a sum of two operators, which obey specific commutation relations. Then, we apply the exponential operator as an evolution operator for the case of elementary unidimensional potentials, like the particle subject to a constant force and the harmonic oscillator. Also, we argue about an apparent paradox concerning the time evolution operator and non-spreading wave packets addressed previously in the literature.Comment: 24 pages; added references; one figure change

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

PURPOSE: The primary aim of the present study was to assess the pharmacokinetic bioequivalence between a generic formulation of meloxicam 15 mg tablets (Meloxicam Hexal) and its respective brand product (Mobic), in order to verify whether the generic product conforms to the regulatory standards of bioequivalence in the postmarketing setting. As a secondary exploratory aim, the pharmacodynamic effects of the two formulations were also evaluated by means of rating scales following hyperalgesia induced by cutaneous freeze injury. SUBJECTS AND METHODS: A single 15 mg dose of generic or branded meloxicam tablets was administered to 24 healthy male volunteers in a crossover fashion. Plasma samples, collected for 24 hours after dosing, were assayed for meloxicam concentration by a validated highperformance liquid chromatography method. RESULTS: THE ANALYSIS OF PHARMACOKINETIC PARAMETERS DID NOT SHOW ANY SIGNIFICANT DIFFERENCE BETWEEN THE TWO MELOXICAM FORMULATIONS: the 90% confidence intervals fell within the acceptance range of 80%-125% (0.84-1.16 for area under the curve [0-24], and 0.89-1.23 for peak concentration). No difference in the pharmacodynamic end point was observed between the two groups. CONCLUSION: The pharmacokinetic profiles of the two meloxicam formulations confirm the regulatory criteria for bioequivalence; pharmacodynamic data indicate a similar antihyperalgesic effect. The two formulations can be used interchangeably in the clinical setting

synchronous angiosarcoma melanoma and morphea of the breast skin 14 years after radiotherapy for mammary carcinoma

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On the Impact of Link Layer Retransmissions on TCP for Aeronautical Communications

In this article, we evaluate the impact of link layer retransmissions on the performance of TCP in the context of aeronautical communications.We present the architecture of aeronautical networks, which is manly driven by an important channel access delay, and the various retransmission strategies that can be implemented at both link and transport layers. We consider a worst case scenario to illustrate the benefits provided by the ARQ scheme at the link layer in terms of transmission delay.We evaluate the trade-off between allowing a fast data transmission and a low usage of satellite capacity by adjusting link layer parameters

Seismicity and seismogenic structures of Central Apennines (Italy): constraints on the present-day stress field from focal mechanisms – The SLAM (Seismicity of Lazio-Abruzzo and Molise) project

The aim of the SLAM (Seismicity of Lazio, Abruzzo and Molise region) project is to provide new insight on the seismotectonic and seismogenesis of a wide portion of central Italy situated between areas affected by recent destructive events such as the 2009, Mw = 6.3, L’Aquila earthquake to the north and the 2002, Mw = 5.8, Molise earthquake to the east. We present new results for the microseismic activity in the Central Apennines, occurred in the period 2009 – 2013, by analyzing seismogram recordings from two temporary networks of up to 17 stations in combination with data from three networks of permanent stations