Examining a Natural Duty of Justice and its Implications

John Rawls crafts a natural duty of justice to legitimize a duty to obey and support a just political institution. In creating this natural duty, Rawls assumes an objective standard of justice, which has significant implications on his natural duty. Political institutions often have aspects of justice and injustice, and in this paper I examine the implications of this gradient of justice and how it affects the resulting duty that Rawls identifies. In addition to this examination, the consequences of an imperfect duty resulting from a political institution which is not perfectly just will also be addressed and Rawls’ principle, undermined

Detection and Mapping of Quantitative Trait Loci that Determine Responsiveness

Exposure to 70% N2O evokes a robust antinociceptive effect in C57BL/6 (B6) but not in DBA/2 (D2) inbred mice. This study was conducted to identify quantitative trait loci (QTL) in the mouse genome that might determine responsiveness to N2O. Offspring from the F2 generation bred from B6 and D2 progenitors exhibited a broad range of responsiveness to N2O antinociception as determined by the acetic acid-induced abdominal constriction test. QTL analysis was then used to dissect this continuous trait distribution into component loci, and to map them to broad chromosomal regions. To this end, 24 spleens were collected from each of the following four groups: male and female F2 mice responding to 70% N2O in oxygen with 100% response (high-responders); and male and female F2 mice responding with 0% response (low-responders). Genomic DNA was extracted from the spleens and genotyped with simple sequence length polymorphism MapPairs markers. Findings were combined with findings from the earlier QTL analysis from BXD recombinant inbred mice [Brain Res 725 (1996) 23]. Combined results revealed two significant QTL that influence responsiveness to nitrous oxide on proximal chromosome 2 and distal chromosome 5, and one suggestive QTL on midchromosome 18. The chromosome 2 QTL was evident only in males. A significant interaction was found between a locus on chromosome 6 and another on chromosome 13 with a substantial effect on N2O antinociception

AOIPS water resources data management system

A geocoded data management system applicable for hydrological applications was designed to demonstrate the utility of the Atmospheric and Oceanographic Information Processing System (AOIPS) for hydrological applications. Within that context, the geocoded hydrology data management system was designed to take advantage of the interactive capability of the AOIPS hardware. Portions of the Water Resource Data Management System which best demonstrate the interactive nature of the hydrology data management system were implemented on the AOIPS. A hydrological case study was prepared using all data supplied for the Bear River watershed located in northwest Utah, southeast Idaho, and western Wyoming

Job Coaching: A Means to Reduce Unemployment and Underemployment in the Deaf Community

Historically, vocational rehabilitation approaches to assisting deaf people to succeed in employment have been lacking. This contributes to unemployment and underemployment among the deaf community. This article discusses barriers to employment experienced by deaf people, the traditional role of vocational rehabilitation services, and service gaps related to job retention and advancement. A model for the provision of job coach services is provided that calls for the coach to be a member of a team providing routine ongoing services. Current and future efforts to develop coach training opportunities are described as well

Integrative Review: Parent Perspectives on Care of Their Child at the End of Life

This integrative review aims to describe parents\u27 perspectives on end-of-life care for their children. Fifteen publications from a literature search of the Cochrane databases, CINAHL, MEDLINE, and PSYCHinfo were included in the review. Recurring themes included poor communication/lack of information, strained relationships/inadequate emotional support, parental need to maintain parent/child relationships in life and death, quality of care continues after the death of the child, influence of services/planning on parent/child impacts quality of life, and the difficult decision to terminate life support. No studies were identified that focused on parents\u27 perspectives on the care their child received at the end of life. Further research that focuses on the special needs of parents at this difficult time is needed

Volume and quality of sand and gravel aggregate in the submerged paleodeltas of the Kennebec and Penobscot River mouth areas, Maine

Maine Geological Survey, Open-File Report 97-5. Reports on results of a geophysical and coring investigation of sand volumes at mouths of Kennebec and Penobscot Rivershttps://digitalmaine.com/mgs_publications/1117/thumbnail.jp

Southeast Asian refugee children: Self-esteem as a predictor of depression and scholastic achievement in the U.S.

The eruption of conflicts and war in this century has led to new masses of refugees and displaced persons. Globally, host countries will continue to confront issues of how to ensure the successful adaptation of refugees who typically are women and children. The United States received three major waves of Southeast Asian (SEA) refugees during the past twenty-five years. One million SEA refugees arrived in the past decade; the majority were children and adolescents. Today, there is still a lack of understanding surrounding mental health issues and their relationship to children\u27s violence experience. We know that SEA refugee children suffered violence during the war in Southeast Asia, their escape from homelands, in camps of asylum and in the U.S. Although researchers have examined the relationship of violence with depression and post-traumatic stress disorder in refugee children, the findings have been unclear and sometimes conflictual in their relationship to scholastic achievement. In the U.S., healthy self-esteem is recognized as an important component of mental health and academic success, while low self-esteem is associated with depression and academic failure. In general, self-esteem and measures of self-esteem have not been studied cross-culturally. The authors report the findings of a measure of self-esteem, depression and academic achievement in a convenience sample of 237 Southeast Asian refugee children aged 6 to 17 years of age in the U.S. Internationally, nurses who assess the mental health of refugee children and design interventions to assist in their adaptation, will want to have an understanding of mental health issues cross-culturally

The seafloor revealed: The geology of the northwestern Gulf of Maine inner continental shelf

Maine Geological Survey, Open-File Report 96-6. Explains the surficial geology, physiography, and geologic history of the Maine coast. Methods and analysis detail how the seafloor was studied. Data were interpreted from side-scan sonar records, seismic reflection profiles, bottom samples, and submersible dives.https://digitalmaine.com/mgs_publications/1118/thumbnail.jp

Development in the Gulf of Maine: Avoiding Geohazards and Embracing Opportunities

Mapping for marine-spatial planning is crucial if Maine is to safely develop its offshore resources, espe­cially wind and tidal energy. The authors focus on shallow natural gas (methane) deposits, an important and widespread geohazard in Maine’s seafloor. They describe the origin, occur­rence, and identification of natural gas in Maine’s seafloor; explain the hazards associated with these deposits and how to map them; and discuss what Maine can learn from European nations that have already developed their offshore wind resources. Because the U.S. gives states a central role in coastal management, Maine has the chance to be proactive in delineating coastal resources and demarcating potential seafloor hazards

Automatically Recognizing Medication and Adverse Event Information From Food and Drug Administration\u27s Adverse Event Reporting System Narratives

BACKGROUND: The Food and Drug Administration\u27s (FDA) Adverse Event Reporting System (FAERS) is a repository of spontaneously-reported adverse drug events (ADEs) for FDA-approved prescription drugs. FAERS reports include both structured reports and unstructured narratives. The narratives often include essential information for evaluation of the severity, causality, and description of ADEs that are not present in the structured data. The timely identification of unknown toxicities of prescription drugs is an important, unsolved problem. OBJECTIVE: The objective of this study was to develop an annotated corpus of FAERS narratives and biomedical named entity tagger to automatically identify ADE related information in the FAERS narratives. METHODS: We developed an annotation guideline and annotate medication information and adverse event related entities on 122 FAERS narratives comprising approximately 23,000 word tokens. A named entity tagger using supervised machine learning approaches was built for detecting medication information and adverse event entities using various categories of features. RESULTS: The annotated corpus had an agreement of over .9 Cohen\u27s kappa for medication and adverse event entities. The best performing tagger achieves an overall performance of 0.73 F1 score for detection of medication, adverse event and other named entities. C ONCLUSIONS: In this study, we developed an annotated corpus of FAERS narratives and machine learning based models for automatically extracting medication and adverse event information from the FAERS narratives. Our study is an important step towards enriching the FAERS data for postmarketing pharmacovigilance