678 research outputs found
Experimental Measurement of the Berry Curvature from Anomalous Transport
Geometrical properties of energy bands underlie fascinating phenomena in a
wide-range of systems, including solid-state materials, ultracold gases and
photonics. Most famously, local geometrical characteristics like the Berry
curvature can be related to global topological invariants such as those
classifying quantum Hall states or topological insulators. Regardless of the
band topology, however, any non-zero Berry curvature can have important
consequences, such as in the semi-classical evolution of a wave packet. Here,
we experimentally demonstrate for the first time that wave packet dynamics can
be used to directly map out the Berry curvature. To this end, we use optical
pulses in two coupled fibre loops to study the discrete time-evolution of a
wave packet in a 1D geometrical "charge" pump, where the Berry curvature leads
to an anomalous displacement of the wave packet under pumping. This is both the
first direct observation of Berry curvature effects in an optical system, and,
more generally, the proof-of-principle demonstration that semi-classical
dynamics can serve as a high-resolution tool for mapping out geometrical
properties
Composing and Factoring Generalized Green's Operators and Ordinary Boundary Problems
We consider solution operators of linear ordinary boundary problems with "too
many" boundary conditions, which are not always solvable. These generalized
Green's operators are a certain kind of generalized inverses of differential
operators. We answer the question when the product of two generalized Green's
operators is again a generalized Green's operator for the product of the
corresponding differential operators and which boundary problem it solves.
Moreover, we show that---provided a factorization of the underlying
differential operator---a generalized boundary problem can be factored into
lower order problems corresponding to a factorization of the respective Green's
operators. We illustrate our results by examples using the Maple package
IntDiffOp, where the presented algorithms are implemented.Comment: 19 page
An improved method for high-throughput quantification of autophagy in mammalian cells
Autophagy is a cellular homeostatic pathway with functions ranging from cytoplasmic protein turnover to immune defense. Therapeutic modulation of autophagy has been demonstrated to positively impact the outcome of autophagy-dysregulated diseases such as cancer or microbial infections. However, currently available agents lack specificity, and new candidates for drug development or potential cellular targets need to be identified. Here, we present an improved method to robustly detect changes in autophagy in a high-throughput manner on a single cell level, allowing effective screening. This method quantifies eGFP-LC3B positive vesicles to accurately monitor autophagy. We have significantly streamlined the protocol and optimized it for rapid quantification of large numbers of cells in little time, while retaining accuracy and sensitivity. Z scores up to 0.91 without a loss of sensitivity demonstrate the robustness and aptness of this approach. Three exemplary applications outline the value of our protocols and cell lines: (I) Examining autophagy modulating compounds on four different cell types. (II) Monitoring of autophagy upon infection with e.g. measles or influenza A virus. (III) CRISPR/Cas9 screening for autophagy modulating factors in T cells. In summary, we offer ready-to-use protocols to generate sensitive autophagy reporter cells and quantify autophagy in high-throughput assays
Spawning rings of exceptional points out of Dirac cones
The Dirac cone underlies many unique electronic properties of graphene and
topological insulators, and its band structure--two conical bands touching at a
single point--has also been realized for photons in waveguide arrays, atoms in
optical lattices, and through accidental degeneracy. Deformations of the Dirac
cone often reveal intriguing properties; an example is the quantum Hall effect,
where a constant magnetic field breaks the Dirac cone into isolated Landau
levels. A seemingly unrelated phenomenon is the exceptional point, also known
as the parity-time symmetry breaking point, where two resonances coincide in
both their positions and widths. Exceptional points lead to counter-intuitive
phenomena such as loss-induced transparency, unidirectional transmission or
reflection, and lasers with reversed pump dependence or single-mode operation.
These two fields of research are in fact connected: here we discover the
ability of a Dirac cone to evolve into a ring of exceptional points, which we
call an "exceptional ring." We experimentally demonstrate this concept in a
photonic crystal slab. Angle-resolved reflection measurements of the photonic
crystal slab reveal that the peaks of reflectivity follow the conical band
structure of a Dirac cone from accidental degeneracy, whereas the complex
eigenvalues of the system are deformed into a two-dimensional flat band
enclosed by an exceptional ring. This deformation arises from the dissimilar
radiation rates of dipole and quadrupole resonances, which play a role
analogous to the loss and gain in parity-time symmetric systems. Our results
indicate that the radiation that exists in any open system can fundamentally
alter its physical properties in ways previously expected only in the presence
of material loss and gain
Impact of dispersive and saturable gain/loss on bistability of nonlinear parity-time Bragg gratings
We report on the impact of realistic gain and loss models on the bistable operation of nonlinear parity–time (PT) Bragg gratings. In our model we include both dispersive and saturable gain and show that levels of gain/loss saturation can have a significant impact on the bistable operation of a nonlinear PT Bragg grating based on GaAs material. The hysteresis of the nonlinear PT Bragg grating is analyzed for different levels of gain and loss and different saturation levels. We show that high saturation levels can improve the nonlinear operation by reducing the intensity at which the bistability occurs. However, when the saturation intensity is low, saturation inhibits the PT characteristics of the grating
Ultrafast optical switching using parity-time symmetric Bragg gratings
This paper reports on time-domain modeling of an optical switch based on the parity–time (PT) symmetric Bragg grating. The switching response is triggered by suddenly switching on the gain in the Bragg grating to create a PT-symmetric Bragg grating. Transient and dynamic behaviors of the PT Bragg gratings are analyzed using the time-domain numerical transmission line modeling method including a simple gain saturation model. The on/off ratio and the switching time of the PT Bragg grating optical switch are analyzed in terms of the level of gain introduced in the system and the operating frequency. The paper also discusses the effect the gain saturation has on the operation of the PT-symmetric Bragg gratings
Evidence for the η_b(1S) Meson in Radiative Υ(2S) Decay
We have performed a search for the η_b(1S) meson in the radiative decay of the Υ(2S) resonance using a sample of 91.6 × 10^6 Υ(2S) events recorded with the BABAR detector at the PEP-II B factory at the SLAC National Accelerator Laboratory. We observe a peak in the photon energy spectrum at E_γ = 609.3^(+4.6)_(-4.5)(stat)±1.9(syst) MeV, corresponding to an η_b(1S) mass of 9394.2^(+4.8)_(-4.9)(stat) ± 2.0(syst) MeV/c^2. The branching fraction for the decay Υ(2S) → γη_b(1S) is determined to be [3.9 ± 1.1(stat)^(+1.1)_(-0.9)(syst)] × 10^(-4). We find the ratio of branching fractions B[Υ(2S) → γη_b(1S)]/B[Υ(3S) → γη_b(1S)]= 0.82 ± 0.24(stat)^(+0.20)_(-0.19)(syst)
A versatile all-optical parity-time signal processing device using a Bragg grating induced using positive and negative Kerr-nonlinearity
The properties of gratings with Kerr nonlinearity and PT symmetry are investigated in this paper. The impact of the gain and loss saturation on the response of the grating is analysed for different input intensities and gain/loss parameters. Potential applications of these gratings as
switches, logic gates and amplifiers are also shown
Solitary waves in the Nonlinear Dirac Equation
In the present work, we consider the existence, stability, and dynamics of
solitary waves in the nonlinear Dirac equation. We start by introducing the
Soler model of self-interacting spinors, and discuss its localized waveforms in
one, two, and three spatial dimensions and the equations they satisfy. We
present the associated explicit solutions in one dimension and numerically
obtain their analogues in higher dimensions. The stability is subsequently
discussed from a theoretical perspective and then complemented with numerical
computations. Finally, the dynamics of the solutions is explored and compared
to its non-relativistic analogue, which is the nonlinear Schr{\"o}dinger
equation. A few special topics are also explored, including the discrete
variant of the nonlinear Dirac equation and its solitary wave properties, as
well as the PT-symmetric variant of the model
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