Effect of various configurations of swirl generator system on the hydrothermal performance of the flat-plate solar collector

This is a numerical study that analysis the heat extraction potential of solar collector tubes by assembling a couple of nozzles at the sealed end of the pipe to make swirl flow. Swirl flow intensifies the turbulence rate which augments heat transfer by ruffling the boundary layer. To this end, several decisive factors including nozzle angle (A: 30�, 45�, 60�, 90�), tube diameter (D: 20 mm, 50 mm), nozzle edge size (N: 6.25, 12.5, 25 mm (for D50) and N: 2.5, 5, 10 mm (for D20)), and mass flow rate (M: 0.1, 0.5, 1 kg/s (for D50) and M: 0.04, 0.2, 0.4 kg/s (for D20)) were considered. Results demonstrated that all of the models of class ’’A.../D20/N.../M...‘‘ had higher heat extraction potential but lower friction factor compared with ”A.../D50/N.../M...‘‘. Maximum and minimum values of heat flux extractions are 2113390 W/m2 and 59239 W/m2 that were obtained by ”A60/ D20/N2.5/M0.400 and ‘‘A30/D50/N25/M0.100. The created friction factor by class ”A.../D50/N .../M...‘‘ is higher than class ’’A.../D20/N.../M...”. The highest friction factor is 3.51 (’’A90/D 20/N2.5/M0.0400) and the lowest friction factor is 0.019 (‘‘A30/D20/N2.5/M0.200). Overall, for all cases, class ”A.../D50/N.../M...‘‘ bear the higher TPF compared with class ”A.../D50/N.../M ...‘‘ so that the greatest and lowest values of TPF are 5.09 and 0.49 achieved by ”A30/D50/N6.2 5/M100 and ‘‘A90/D20/N5/M0.400, respectively

Splenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis

In polytrauma patients, the impact of splenectomy is equivocal, ranging from negative to protective. We investigated the impact of splenectomy on immune responses in the 1st-hit polytrauma alone and on survival in the post-traumatic sepsis (2nd hit). Female BALB/c mice underwent polytrauma (1st hit) consisting of either a) TH: femur fracture, hemorrhagic shock or b) TSH: splenectomy, femur fracture, hemorrhagic shock. Additionally, the polytrauma hit was followed by cecal ligation and puncture (CLP) 48 h later and compared to CLP alone. Splenectomy improved the 28-day survival in secondary sepsis to 92% (from 62%), while TH lowered it to 46% (p < 0.05). The improved survival was concurrent with lower release of inflammatory cytokines (IL-6, CXCL-1, MCP-1) and increase of C5a post-CLP. In the polytrauma hit alone, TSH induced stronger neutrophilia (1.9 fold) and lymphocytosis (1.7 fold) when compared to TH mice. Moreover, TSH resulted in a 41% rise of regulatory T-cells and reduced the median fluorescence intensity of MHC-2 on monocytes by 55% within 48 h (p < 0.05). Conversely, leukocyte phagocytic capacity was significantly increased by 4-fold after TSH despite a similar M1/M2 macrophage profile in both groups. Summarizing, splenectomy provoked both immuno-suppressive and immuno-stimulatory responses but was life-saving in secondary sepsis. Additionally, the polytrauma components in 2-hit models should be tested for their effects on outcome; the presumed end-effect of the 1st hit solely based on the common immuno-inflammatory parameters could be misleading

Systemic inhibition and liver-specific over-expression of PAI-1 failed to improve survival in all-inclusive populations or homogenous cohorts of CLP mice

International audienc

Optimal exergy-based control of internal combustion engines

© 2016 Elsevier Ltd Exergy or availability is defined as the maximum useful work during a process. This metric has been used to analyze and understand loss mechanisms of Internal Combustion Engines (ICEs). In this paper, an optimal control method based on exergy is introduced for transient and steady state operation of ICEs. First, an exergy model is developed for a single cylinder Ricardo engine. The ICE exergy model is based on the Second Law of Thermodynamics (SLT) and characterizes irreversibilities. Such quantifications are not identified in the First Law of Thermodynamics (FLT) analysis. For steady-state operation of the ICE, a set of 175 different operating conditions is used to construct the SLT efficiency maps. Two different SLT efficiency maps are generated depending on the applications whether work, or Combined Power and Exhaust Exergy (CPEX) is the desired output. To include transient ICE operation, a model to predict exergy loss/destruction during engine transients is developed. The sources of exergy destruction/loss are identified for a Homogeneous Charge Compression Ignition (HCCI) engine. Based on the engine operating conditions (i.e., steady-state or transient) SLT efficiency contour maps or predicted exergy losses are determined at every given engine load. An optimization algorithm is proposed to find the optimum combustion phasing to maximize the SLT efficiency. Application of the optimization algorithm is illustrated for combustion phasing control. The results show that using the exergy-based optimal control strategy leads to an average of 6.7% fuel saving and 8.3% exergy saving compared to commonly used FLT based combustion control in which a fixed combustion phasing (e.g., 8°aTD) is used