'Working our way to health': Final Evaluation Report

This summary presents the findings of an independent evaluation of the ‘Working our Way to Health’ programme. This programme was delivered by Sefton PCT, funded through the Neighbourhood Renewal Fund, and was aimed at improving the health of men in three of the most deprived wards in its locality. It aimed to encourage men to be health aware and increase access to health and leisure services in order to improve key lifestyle behaviours and advance gender equity. The programme included: • Community agency and health staff training • Peer mentoring programme • Healthy lifestyle programme It aimed to promote community partnerships to assist the expansion of health advice and services into a new community arena and engage a previously unattainable section of the male population in healthier lifestyle interventions

Exploring the Emotional Impact of Breastfeeding Difficulties in the Context of Continued Breastfeeding.

PETITION FOR REVIEW TO THE UTAH COURT OF APPEALS FROM THE INDUSTRIAL COMMISSION OF UTA

Red blood cell exchange for SARS-CoV-2: A Gemini of therapeutic opportunities

© 2020 Elsevier Ltd As of now, therapeutic strategies for the novel coronavirus (SARS-CoV-2) are limited and much focus has been placed on social distancing techniques to “flatten the curve”. Initial treatment efforts including ventilation and hydroxychloroquine garnered significant controversy and today, SARS-CoV-2 outbreaks are still occurring throughout the world. Needless to say, new therapeutic strategies are needed to combat this unprecedented pandemic. Nature Reviews Immunology recently published an article hypothesizing the pathogenesis of TAM (Tyro3, Axl, and Mer) receptor signaling in COVID-19. In it they expressed that hypercoagulation and immune hyper-reaction could occur secondary to decreased Protein S (PROS1). And hypoxia has been recently discovered to significantly decrease expression of PROS1. Regarding the cause of hypoxia in COVID-19; NIH funded research utilizing state-of-the-art topologies has recently demonstrated significant metabolomic, proteomic, and lipidomic structural aberrations in hemoglobin (Hb) secondary to infection with SARS-CoV-2. In this setting, Hb may be incapacitated and unable to respond to environmental variations, compromising RBCs and oxygen delivery to tissues. The use of red blood cell exchange would target hypoxia at its source; representing a Gemini of therapeutic opportunities

High resolution mapping of Puget Sound shorelines

In an effort to collect high-resolution baseline coastal topographic data of beaches and bluffs around the Puget Sound and Strait of Juan de Fuca, the Washington State Department of Ecology Coastal Monitoring & Analysis Program (CMAP) conducted a series of boat-based lidar surveys in October 2013, May through September 2015, and May 2016 at a total of 16 sites spanning 220 km of shoreline and over two dozen drift cells. The drift cells were selected based on a rigorous and systematic geospatial analysis of bluff-backed beaches for their potential for significant bluff sediment supply to intact shorelines identified as having a relative abundance of habitat for forage fish, eelgrass, herring, shellfish, and geoduck, as well as having previous investments in beach restoration projects, and potential for future shoreline armoring and habitat loss based on population growth scenarios. As such, the surveyed drift cells are top candidates for implementing drift cell-scale protection and restoration strategies. The boat-based lidar and GPS topography data were used to produce 0.5-m digital elevation models (DEMs) for the beaches and bluffs at each of the survey sites. These DEMs provide the opportunity to inventory and characterize the shoreline landscape that affects nearshore ecosystem services such as feeder bluff activity, beach slope and width, and the position, length, and elevation of armoring relative to the backshore. Boat-based lidar provides an advantageous point of view of the bluff face, resulting in high resolution data which is needed to gain insight into bluff failure and erosion mechanisms and corresponding sediment transport processes. In addition, it successfully collects data under overhanging vegetation and overwater structures. Repeat surveys in the future would enable change analyses for quantifying bluff sediment supply, changes in marine riparian vegetation, and a better understanding of the linkages between physical and ecological processes

A Case of Multisystem Inflammatory Syndrome in Children Mimicking Acute Appendicitis in a COVID-19 Pandemic Area.

The outbreak of the novel coronavirus (2019-nCoV) began in Wuhan, China and spread rapidly throughout the world. As of now, there have been numerous reports demonstrating clinical, radiological and pathological findings in adults. In children, the disease has essentially been seen as mild and self-limiting. However, more recently, children have been presenting with findings reminiscent of Kawasaki\u27s disease. And secondary to this, the benign nature of COVID-19 disease in children is beginning to be challenged. This phenomenon is now referred to as multisystem inflammatory syndrome in children (MIS-C). Further understanding the clinical course in MIS-C and its temporal association with coronavirus disease 2019 will be paramount for treatment and public health decision making. This correspondence describes a case of MIS-C with gastrointestinal manifestations mimicking acute appendicitis in a child presenting from a COVID-19 endemic area

Evaluating methods to obtain high resolution nearshore bathymetry and coastal topography for Puget Sound

The Washington State Department of Ecology Coastal Monitoring & Analysis Program performed a coastal topographic and bathymetric survey of Port Gamble Bay between March 9 and March 28, 2014. Boat-based topographic lidar was collected along the shoreline of the bay and multibeam bathymetric sonar was collected throughout the bay to obtain a seamless topographic-bathymetric surface with complete coverage of Port Gamble Bay. The survey was performed with a R2Sonic 2022 multibeam echosounder, an Optech ILRIS-HD-ER mobile laser scanner, and an Applanix POS MV 320 v5 receiving real-time kinematic positioning corrections. The Joint Airborne Lidar Bathymetry Technical Center of Expertise (JALBTCX) performed a topographic and bathymetric lidar survey of Port Gamble Bay on September 4, 2014. The Coastal Zone Mapping and Imaging Lidar (CZMIL) system was used to obtain seamless coastal topographic-bathymetric coastal intertidal and nearshore coverage of Port Gamble Bay. The bathymetric depth coverage is limited to laser extinction, which is determined by water clarity. The availability of these two datasets provides the unique opportunity to compare data between high-resolution boat-based lidar and multibeam systems and the state-of-the-art airborne topo-bathy lidar system and also assess detection and resolution of specific features throughout a range of water depths across the nearshore important to habitat and restoration efforts. This effort provides a detailed comparison of coverage and resolution of nearshore features and will help clarify differences between these capabilities to aid in planning complementary efforts in coastal zone mapping and monitoring

Large-scale structure in a new deep IRAS galaxy redshift survey

We present here the first results from two recently completed, fully sampled redshift surveys comprising 3703 IRAS Faint Source Survey (FSS) galaxies. An unbiased counts-in-cells analysis finds a clustering strength in broad agreement with other recent redshift surveys and at odds with the standard cold dark matter model. We combine our data with those from the QDOT and 1.2 Jy surveys, producing a single estimate of the IRAS galaxy clustering strength. We compare the data with the power spectrum derived from a mixed dark matter universe. Direct comparison of the clustering strength seen in the IRAS samples with that seen in the APM-Stromlo survey suggests b_O/b_I=1.20+/-0.05 assuming a linear, scale independent biasing. We also perform a cell by cell comparison of our FSS-z sample with galaxies from the first CfA slice, testing the viability of a linear-biasing scheme linking the two. We are able to rule out models in which the FSS-z galaxies identically trace the CfA galaxies on scales 5-20h^{-1}Mpc. On scales of 5 and 10h^{-1}Mpc no linear-biasing model can be found relating the two samples. We argue that this result is expected since the CfA sample includes more elliptical galaxies which have different clustering properties from spirals. On scales of 20h^{-1}Mpc no linear-biasing model with b_O/b_I < 1.70 is acceptable. When comparing the FSS-z galaxies to the CfA spirals, however, the two populations trace the same structures within our uncertaintie

Effects of Uniform and Differential Rotation on Stellar Pulsations

We have investigated the effects of uniform rotation and a specific model for differential rotation on the pulsation frequencies of 10 \Msun\ stellar models. Uniform rotation decreases the frequencies for all modes. Differential rotation does not appear to have a significant effect on the frequencies, except for the most extreme differentially rotating models. In all cases, the large and small separations show the effects of rotation at lower velocities than do the individual frequencies. Unfortunately, to a certain extent, differential rotation mimics the effects o f more rapid rotation, and only the presence of some specific observed frequencies with well identified modes will be able to uniquely constrain the internal rotation of pulsating stars.Comment: 33 pages, 16 figures. Accepted for publication in Ap