A importância dos Sistemas de Informação Geográfica para as políticas públicas.

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An empirical analysis of habit and addiction to antibiotics

Because of bacterial resistance, current antibiotic consumption is reinforced by past use, and future utility is lower. The purpose of this article is to provide evidence on habit and addictive behavior toward antibiotics by exploring variations in the average consumption of antibiotics across 20 Italian regions. Using a balanced panel data set (2000-2009), we estimate myopic and rational addiction models, in which antibiotic consumption depends upon demographic and socioeconomic characteristics of the population, the supply of health care in the community, antibiotic price, and the "capital stock” of endogenous bacterial resistance measured by past and future consumption. Our empirical evidence shows that past antibiotic consumption stimulates current consumption and is also consistent with the rational addiction hypothesis. The low price elasticity of antibiotic demand suggests that policy measures targeted at antibiotic co-payments may not be effective in controlling antibiotic consumption. There is scope for other policy interventions, such as incentives and information campaigns targeted at doctor

Geociências: As bases do desenvolvimento sustentável.

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Os impactos ambientais no contexto da sustentabilidade.

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Use of Perylene Diimides in Synthetic Photochemistry

Perylene diimides (PDIs) are valuable organic chromophores that stand out for their outstanding optical and redox properties. Owing to these features, PDIs have emerged as prominent dyes capable of acting as photocatalysts for numerous relevant organic transformations. This Minireview highlights the recent advances in the application of PDIs in organic photocatalysis. The various mechanistic pathways of the photo-reduction reaction of aryl halides, recently proposed in independent studies, are discussed with an eye to unsolved challenges and forward-looking opportunities regarding the use of PDIs within this field

Assessment of multiaxial fatigue life prediction methodologies for Inconel 718

Abstract Fatigue life prediction methodologies for the assessment of the structural integrity of safety critical components in modern turbine engines require a close integration of advanced multiaxial fatigue life prediction procedures and of specific multiaxial tests, representative of the service conditions of turbine engine components and materials. The objective of the research work presented in this paper is to extend currently employed methodologies for the assessment of fatigue strength of turbine engines disks by integrating suitable multiaxial fatigue criteria and test results of multiaxial fatigue experiments conducted on Inconel 718 material at temperatures similar to those experienced by the disc materials during service. Smooth tubular specimens of Inconel 718 have been employed for conducting tension/torsion strain controlled high temperature fatigue tests. Specimens have been cut out from forged parts utilised for the production of engine discs, thus preserving the typical properties of disc materials (microstructure, basic mechanical properties, etc.). Different models/criteria have been evaluated by comparing fatigue life predictions and multiaxial fatigue experiments. It's well known that agreement of life predictions with experimental life is strongly affected not only by the choice of the multiaxial fatigue criteria but also by the way the reference fatigue data are integrated in the criteria. Therefore, specific multiaxial fatigue tests have been carried out, in order to validate and to improve the assessment capabilities of the lifing procedures. Moreover, multiaxial fatigue tests permit advances in the basic understanding of materials behaviour that might be utilised in the processes of declaring component service lives