226 research outputs found

    Price Performance of IPOS in Indian Stock Market

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    The present study   has been undertaken to gauge the underpricing in NSE in the short run periods, i.e., from the listing day to the six months after the listing and for the long period. The results depict that the presence of underpricing.   The study also tries to analyse the influence of factors on IPOs pricing performance. The results show that these factors viz. Subscription level, Issue size, Listing lead time and Age influence the initial returns, i.e., R_Ret. of the listing day of the company

    Aflatoxin B1 production in chillies (Capsicum annuum L.) kept in cold stores

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    An attempt has been made to isolate and enumerate the mycoflora invading chillies kept in cold storage since May, 1999. Chilli pods were collected from the cold stores at monthly intervals for a period of one year between December 2002 to November 2003. The incidence of molds on unsterilized as well as surface sterilized samples was recorded. Species of Aspergillus found to be dominant on stored chillies were screened for antimicrobial activity. The toxins from A. flavus and A. niger exhibited antibacterial and antifungal activity. Incidences of Alternaria alternata, Fusarium spp. and Mucor spp. was low on stored chillies when compared to Aspergillus spp. Chilli seeds aseptically collected from the pods were also tested for mycoflora. Natural occurrence of aflatoxin B1 in chilli pods kept in cold storage was tested. Results from HPLC analysis revealed that the samples were contaminated with aflatoxin B1 to the extent of 5.5 &#181g Kg-1. Key words: Chillies, aflatoxin B1, cold storage.African Journal of Biotechnology Vol. 4 (8), pp. 791-79

    Clinical manifestation and prevalence of peripheral neuropathy and nerve dysfunction in patients with chronic kidney disease

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    Background: Chronic Kidney Disease (CKD) is recognized as a major health problem. Prevalence of CKD is rising continuously; mostly CKD is affecting the elderly aged population and/or patients with diabetes and hypertension. Present study was aimed to explore clinical manifestation and evaluate the prevalence of peripheral neuropathy and peripheral nerve dysfunction in CKD patients attending our hospital with reference to the severity and duration of the CKD.Methods: The present cross sectional study was conducted in 74 patients affected with chronic kidney disease, of different age groups at the medical wards of King George Hospital, Visakhapatnam. The presence of peripheral nerve dysfunction was assessed by nerve dysfunction clinically (motor or sensory symptoms and signs) and electrophysiological nerve conduction studies.Results: Out of 74 patients, 65% of study population was suffering from chronic kidney disease with peripheral nerve dysfunction. The peripheral nerves dysfunction was more prevalent in elder age (>65 years) subjects when compared to subjects with age <65 years. Moreover, the results shown that the rate of prevalence of peripheral nerves dysfunction was observed higher in subjects with longer duration of CKD. Male subjects were affected more when creatinine clearance is <15 ml/minute. Both sexes were affected equally when creatinine clearance is between 30-59 ml/minute.Conclusion: This study enlightens the prevalence and clinical presentation of peripheral nerve dysfunction in patients with CKD. The CKD was found to cause peripheral neuropathy including overt and subclinical neuropathy, of which distal symmetrical sensory motor neuropathy was common in CKD. The prevalence of peripheral neuropathy was directly proportional to duration and severity of CKD.

    System Architecture for Low-Power Ubiquitously Connected Remote Health Monitoring Applications With Smart Transmission Mechanism

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    We present a novel smart transmission technique with seamless handoff mechanism to achieve ubiquitous connectivity using multiple on-chip radios targeting remote health monitoring applications. For the first time to the best of our knowledge, a system architecture for low-power ubiquitously connected multiparametric remote health monitoring system is proposed in this paper. The architecture proposed uses a generic adaptive rule engine for classifying the collected multiparametric data from patient and smartly transmit the data when only needed. The on-chip seamless handoff mechanism proposed aids for the ubiquitous connectivity with a very good energy savings by intelligent controlling of the multiple on-chip radios. The performance analysis of the proposed on-chip seamless handoff mechanism along with adaptive rule engine-based smart transmission mechanism achieves on an average of 50.39% of energy saving and 51.01% reduction in duty cycle of transmitter taken over 20 users compared with the continuous transmission. From the hardware complexity analysis made on the proposed seamless handoff controller and adaptive rule engine concludes that they require only 2082 CMOS transistors for real-time implementation

    DRIVER CAUTION SYSTEM FOR SAFETY USING SMART LED DISPLAY BOARDS

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    To prevent accidents and also to alert the motorists concerning the speed limits such type of places the highway department have placed the signboards. Nowadays individuals are driving extremely fast, accidents are occurring frequently, we lost our valuable existence by looking into making small mistake while driving (zone wise, hillsides area, highways). But, May too easy to view that sort of signboards and there's a way for accident. To intimate the motive force concerning the posted speed limit at zones and also to identify crashes instantly, is completed by way of using MEMS, RF, Gps navigation, GSM technology. The primary objective would be to design a good Display controller intended for vehicle’s posted speed limit and crash alerts which could operate on an embedded system. Smart Display &amp; Control (SDC) could be custom-designed to suit right into a vehicle’s dashboard, and displays info on the automobile

    AN EMBEDDED DEVICE TO REGULATE AIR CIRCULATION IN HOT CONDITIONS IN A VEHICLE SYSTEM

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    Microcontroller controls the positioning of the home windows autonomously and individually from the driver’s presence, following predefined formula that utilizes sensors data acquired in the vehicle’s surroundings. The module is implemented utilizing a microcontroller like a central logical unit and a number of sensors which offer sufficient data to make sure functional, but additionally efficient, reliable and safe ventilation and safety of passengers. To be able to mitigate overheated interior of the vehicle parked within the hot summer time sun and therefore to help make the getting into the automobile much more comfortable, and stopping passengers from injuries when accident occurs, microcontroller managed module for automatic ventilation of car interior is created. The ventilation process is conducted by opening vehicle home windows slightly, which helps air to flow. Besides temperature, the most crucial factors to make sure quality implementation of ventilation are detected movements round the vehicle, the existence of humidity along with other. As well as microcontroller controls airbags position. This project uses controlled 5V, 500mA power. 7805 three terminal current regulator can be used for current regulation. Bridge type full wave rectifier can be used to rectify the ac creation of secondary of 230/12V step lower transformer. Using the vibration sensor data for enabling the environment bags open when accident happened towards the vehicle. This paper shows the constituents, their intention and abilities, pros and cons, in addition to potential implementations and upgrades. The exam results give understanding of utilization options of the module and it is effectiveness

    Separation of <i>cis/trans</i> fatty acid isomers on gas chromatography compared to the Ag-TLC method

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    The present study investigates the separation of the <i>cis/trans</i> isomers of fatty acids on the 75 m SP2560 column under different gas chromatographic (GC) conditions including an isothermal program and a time-temperature program. The time-temperature program showed improved separation of <i>cis/trans</i> isomers of C<sub>14:1</sub>, C<sub>16:1</sub>, C<sub>18:1</sub>, C<sub>18:2</sub> and C<sub>18:3</sub> fatty acids along with short chain fatty acids compared to the isothermal program. The separation of <i>trans/trans</i> isomers of C<sub>18:1</sub> fatty acids including elaidic acid (C<sub>18:1</sub> ∆9t) and vaccenic acid (C<sub>18:1</sub> ∆11t) was difficult with the time-temperature program. The thin layer chromatography impregnated with silver nitrate (Ag- TLC) method was performed to separate <i>cis/trans</i> fractions and GC analysis was carried out with the <i>trans</i> fraction. But GC analysis showed a co-elution of trans isomers of C<sub>18:1</sub> fatty acid. Thus the study shows that a time-temperature programmed GC method with the highly polar cyanopropyl column is sufficient to resolve trans fatty acids along with short chain fatty acids when a large number of samples has to be analyzed.<br><br>El presente estudio investiga la separación de isómeros <i>cis/trans</i> de ácidos grasos mediante cromatografía de gases (GC) utilizando una columna de SP2560 de 75 m y diferentes condiciones que incluyen un programa isotérmico y una programación temperatura-tiempo. La programación temperatura- tiempo mostró una mejor separación de isómeros cis / trans de los ácidos grasos C<sub>14:1</sub>, C<sub>16:1</sub>, C<sub>18:1</sub>, C<sub>18:2</sub> y C<sub>18:3</sub> con los ácidos grasos de cadena corta en comparación con el programa isotermo. La separación de los isómeros trans/trans de los ácidos grasos C<sub>18:1</sub> incluyendo ácido elaídico (C<sub>18:1</sub> Δ9t) y ácido vaccénico (C<sub>18:1</sub>Δ11t) fué difícil mediante programación temperatura-tiempo. La cromatografía en capa fina impregnada con nitrato de plata (Ag-TLC) se realizó para separar fracciones cis/trans y el análisis de la fracciones se llevó a cabo mediante GC. El análisis GC mostró co-elución de los isómeros <i>trans</i> del ácido graso C<sub>18:1</sub>. Así, el estudio muestra que una programación temperatura-tiempo en GC con columna de cianopropilo altamente polar es suficiente para resolver los ácidos grasos trans, junto con los ácidos grasos de cadena corta cuando un gran número de muestras tiene que ser analizado

    An Effective Strategy for the Synthesis of Biocompatible Gold Nanoparticles Using Cinnamon Phytochemicals for Phantom CT Imaging and Photoacoustic Detection of Cancerous Cells

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    This is a post-print version of the Pharmaceutical Research Article. The original publication is available at www.springerlink.com. DOI 10.1007/s11095-010-0276-6Purpose: The purpose of the present study was to explore the utilization of cinnamon coated gold nanoparticles (Cin-AuNPs) as CT/optical contrast enhancement agent for detection of cancer cells. Methods: Cin-AuNPs were synthesized by a “Green” procedure and the detailed characterization has been performed by physic-chemical analysis. Cytotoxicity and cellualar uptake studies were carried out in normal human fibroblast and cancerous (PC-3 and MCF-7) cells respectively. The efficacy of detecting cancerous cells was monitored using photoacoustic technique. In vivo biodistribution was studied after IV injection of Cin-AuNPs in mice and a CT phantom model was generated. Results: Biocompatible Cin-AuNPs were synthesized with high purity. Significant uptake of these gold nanoparticles was observed in PC-3 and MCF-7 cells. Cin-AuNPs internalized in cancerous cells facilitate detectable photoacoustic signals. In vivo biodistribution in normal mouse shows steady accumulation of gold nanoparticles in lungs and rapid clearance from blood. Quantitative analysis of CT values in phantom model reveals that the cinnamon phytochemicals coated AuNPs has reasonable attenuation efficiency. Conclusions: The results indicate that these non-toxic Cin-AuNPs can serve as excellent CT/ photoacoustic contrast enhancement agents and may provide a novel approach toward the tumor detection through nanopharmaceuticals.This work has been supported by grants from the National Institutes of Health/National Cancer Institute under the Cancer Nanotechnology Platform program (grant number: 5R01CA119412-01), NIH - 1R21CA128460-01; NIH-SBIR-Contract no. 241, and University of Missouri-Research Board - Program C8761 RB 06-030
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