A Novel Approach of Determining the Risks for the Development of Hyperinsulinemia in the Children and Adolescent Population Using Radial Basis Function and Support Vector Machine Learning Algorithm

Hyperinsulinemia is a condition with extremely high levels of insulin in the blood. Various factors can lead to hyperinsulinemia in children and adolescents. Puberty is a period of significant change in children and adolescents. They do not have to have explicit symptoms for prediabetes, and certain health indicators may indicate a risk of developing this problem. The scientific study is designed as a cross-sectional study. In total, 674 children and adolescents of school age from 12 to 17 years old participated in the research. They received a recommendation from a pediatrician to do an OGTT (Oral Glucose Tolerance test) with insulinemia at a regular systematic examination. In addition to factor analysis, the study of the influence of individual factors was tested using RBF (Radial Basis Function) and SVM (Support Vector Machine) algorithm. The obtained results indicated statistically significant differences in the values of the monitored variables between the experimental and control groups. The obtained results showed that the number of adolescents at risk is increasing, and, in the presented research, it was 17.4%. Factor analysis and verification of the SVM algorithm changed the percentage of each risk factor. In addition, unlike previous research, three groups of children and adolescents at low, medium, and high risk were identified. The degree of risk can be of great diagnostic value for adopting corrective measures to prevent this problem and developing potential complications, primarily type 2 diabetes mellitus, cardiovascular disease, and other mass non-communicable diseases. The SVM algorithm is expected to determine the most accurate and reliable influence of risk factors. Using factor analysis and verification using the SVM algorithm, they significantly indicate an accurate, precise, and timely identification of children and adolescents at risk of hyperinsulinemia, which is of great importance for improving their health potential, and the health of society as a whole

IL-33/ST2 Pathway and Galectin-3 as a New Analytes in Pathogenesis and Cardiometabolic Risk Evaluation in Psychosis

Schizophrenia and treatment of this disorder are often accompanied with metabolic syndrome and cardiovascular issues. Alterations in the serum level of innate immune mediators, such as interleukin-33 (IL-33) and its receptor IL-33R (ST2) and Galectin-3 (Gal-3) were observed in these conditions. Moreover, these parameters are potential prognostic and therapeutic markers. There is also accumulating evidence that these molecules play a role in neuroinflammation. Therefore, in this study we have investigated the serum level of Gal-3, IL-33 and soluble ST2 (sST2) in different stages of schizophrenia. Gal-3 levels were elevated in remission and lower in schizophrenia exacerbation in comparison with controls. Levels of IL-33 and sST2 are higher in schizophrenia exacerbation in comparison with controls and patients in remission. This initial analysis of new markers of neuroinflammation suggested their involvement in schizophrenia pathophysiology and/or cardiometabolic comorbidity

Diagnostic Accuracy of Platelet Count and Platelet Indices in Noninvasive Assessment of Fibrosis in Nonalcoholic Fatty Liver Disease Patients

Objective. Keeping in mind the rising prevalence of nonalcoholic fatty liver disease (NAFLD) and the need to establish noninvasive tests for its detection, the aim of our study was to investigate whether platelet count (PC), mean platelet volume (MPV), and platelet distribution width (PDW) can predict the presence of liver fibrosis in this group of patients. Methods. In 98 patients with NAFLD and 60 healthy volunteers, complete blood counts with automated differential counts were performed and values of PC, PDW, MPV, and PCT were analyzed. Results. Patients with NAFLD had lower PC and higher MPV, PCT, and PDW compared to the controls (P < 0.05). When NAFLD group was stratified according to severity of liver fibrosis, there was a statistically significant difference in the average values of PDW and PC between the groups (P < 0.05). Conclusion. Patients with NAFLD have significantly higher values of PCT, PDW, and MPV when compared to the healthy controls. Further studies are needed to establish their potential use for prediction of the degree of liver steatosis and fibrosis in NAFLD patients

HERSUS Sharing Platform [Commendation at 44th Salon of Architecture]

The HERSUS Sharing Platform is a digital platform for researchers and students conceived as an educational tool and archive of resources around the topics of sustainability and heritage awareness in architecture and urban design. The platform has been designed and developed as a source of reference and inspiration to refer to when doing research in the fields that the HERSUS project aims to investigate. In the platform, links are created between apparently distant subjects, showing underlying narratives, connections and overlappings that bring contents together on different levels

Open House Seville - Exhibition

On 11 May 2023, in the framework of the USE HERSUS Event series, the USE OPEN HOUSE activity of the international HERSUS project took place. The Open House was organized in a form of exhibition which consists of three parts: (1) RESULTS OF THE HERSUS STUDENT WORKSHOPS (The brief preview of the Syllabuses and Student Results – research and designs), (2) AWARDED PROPOSALS OF THE HERSUS PRIZE ON MODERN HERITAGE (The awarded, finalist and shortlisted proposals for each of 4 categories – Edu- cation Students, Education Instructors, Practice, and Research), and (3) PRESENTATION OF HERSUS INTELLECTUAL OUTPUTS AND OTHER ACTIVITIES (Timeline of the HERSUS Intellectual outputs followed by presenta- tion of organized events and main achievements including HERSUS in numbers presentation) The exhibition was held at the LOBBY OF THE USE SCHOOL OF ARCHITECTURE ETSAS with participation and interest of local students, academics, and representatives from practice. Moreover, USE Team organized School tour for all HERSUS Partners and exhibition visitors in order to introduce the school profile and student life.HERSUS Consortium Vladan Djokić, Ana Radivojević, Ana Nikezić, Jelena Živković, Nataša Ćuković Ignjatović, Milica Milojević, Jelena Ristić Trajković, Aleksandra Milovanović, Aleksandra Djordjević, Mladen Pešić, Ana Zorić, Bojana Zeković, Tamara Popović, Nevena Lukić, Emanuela Sorbo, Enrico Anguillari, Sofia Tonello, Irene Sgarro,Maria Philokyprou, Aimilios Michael, Andreas Savvides, Panayiota Pyla, Odysseas Kontovourkis, Stavroula Thravalou, Maria Nodaraki, Theodora Hadjipetrou, Konstantinos Sakantamis, Alkmini Paka, Kleoniki Axarli, Maria Doussi, Angeliki Chatzidimitriou, Sofoklis Kotsopoulos, Mar Loren-Méndez, José Peral López, Enrique Larive, Julia Rey, Marta García de Casasola Gómez, María Carrascal, Daniel Pinzón-Ayala, María Álvarez de los Corrales, Roberto Alonso-Jiménez. Учесници: Архитектонски факултет, Универзитет у Београду (Србија), IUAV University of Venice (Италија), University of Cyprus (Кипар), Aristotle University of Thessaloniki (Грчка), и University of Seville – UNESCO Chair on Built Urban Heritage CREhAR in the digital era (Шпанија)

Hersus пројекат и дигитална платформа дељења (2020–2023) [65. Међународни сајам технике и техничких достигнућа]

HERSUS je Erasmus + стратешко партнерство које окупља пет универзитета из Србије, Италије, Кипра, Грчке и Шпаније који заједно раде на дизајну и развоју иновативних интелектуалних исхода и изградњи дигиталне платформу дељења. HERSUS платформа дељења је дигитална платформа за истраживаче и студенте замишљена као архива ресурса о темама одрживости и свести о наслеђу у архитектури и урбанизму. У платформи се стварају везе између наизглед удаљених тема, показујући основне наративе, везе и преклапања која се налазе на различитим просторним и друштвеним нивоима.Учесници: Архитектонски факултет, Универзитет у Београду (Србија), IUAV University of Venice (Италија), University of Cyprus (Кипар), Aristotle University of Thessaloniki (Грчка), и University of Seville – UNESCO Chair on Built Urban Heritage CREhAR in the digital era (Шпанија). HERSUS Consortium Vladan Djokić, Ana Radivojević, Ana Nikezić, Jelena Živković, Nataša Ćuković Ignjatović, Milica Milojević, Jelena Ristić Trajković, Aleksandra Milovanović, Aleksandra Djordjević, Mladen Pešić, Ana Zorić, Bojana Zeković, Tamara Popović, Nevena Lukić, Emanuela Sorbo, Enrico Anguillari, Sofia Tonello, Irene Sgarro,Maria Philokyprou, Aimilios Michael, Andreas Savvides, Panayiota Pyla, Odysseas Kontovourkis, Stavroula Thravalou, Maria Nodaraki, Theodora Hadjipetrou, Konstantinos Sakantamis, Alkmini Paka, Kleoniki Axarli, Maria Doussi, Angeliki Chatzidimitriou, Sofoklis Kotsopoulos, Mar Loren-Méndez, José Peral López, Enrique Larive, Julia Rey, Marta García de Casasola Gómez, María Carrascal, Daniel Pinzón-Ayala, María Álvarez de los Corrales, Roberto Alonso-Jiménez (2022)

Open House Venice - Exhibition

On 1 APRIL 2023, in the framework of the IUAV OPEN DAY, the Iuav OPEN HOUSE activity of the international HERSUS project took place. For the occasion, the area dedicated to the University's Master's and Bachelor's degree courses in Architecture hosted Hersus POSTERS, DIGITAL MATERIALS AND POSTCARDS for the presentation of the 4 published Intellectual Outputs (01: Review of the Best Practices on Educating Sustainability and Heritage, 02: Questionnaire for the State of Art, 03: Statements for Teaching through Design for Sustainability of the Built Environment and Heritage Awareness, 04: HERSUS Sharing Platform), the 3 International Workshops (C2: Student Workshop 1: Sustainable Reconstruction in Urban Areas; C3: Student Workshop 2: Adaptive Reuse; C4: Student Workshop 3: Resilience and Climate Change) and the dissemination activities of the project, such as international conferences (C1: Seminar for Teachers: Teaching through design for Sustainability of the Built Environment and Heritage Awareness; E1: HERSUS Intro Presentation; E2: Presentation of the professional profile) and awards (HERSUS International Prize on Modern Built Heritage). At the event participated MORE THAN 1.250 PEOPLE, including students, parents and teachers from secondary schools and first and second-level university cycles.HERSUS Consortium Vladan Djokić, Ana Radivojević, Ana Nikezić, Jelena Živković, Nataša Ćuković Ignjatović, Milica Milojević, Jelena Ristić Trajković, Aleksandra Milovanović, Aleksandra Djordjević, Mladen Pešić, Ana Zorić, Bojana Zeković, Tamara Popović, Nevena Lukić, Emanuela Sorbo, Enrico Anguillari, Sofia Tonello, Irene Sgarro,Maria Philokyprou, Aimilios Michael, Andreas Savvides, Panayiota Pyla, Odysseas Kontovourkis, Stavroula Thravalou, Maria Nodaraki, Theodora Hadjipetrou, Konstantinos Sakantamis, Alkmini Paka, Kleoniki Axarli, Maria Doussi, Angeliki Chatzidimitriou, Sofoklis Kotsopoulos, Mar Loren-Méndez, José Peral López, Enrique Larive, Julia Rey, Marta García de Casasola Gómez, María Carrascal, Daniel Pinzón-Ayala, María Álvarez de los Corrales, Roberto Alonso-Jiménez. Учесници: Архитектонски факултет, Универзитет у Београду (Србија), IUAV University of Venice (Италија), University of Cyprus (Кипар), Aristotle University of Thessaloniki (Грчка), и University of Seville – UNESCO Chair on Built Urban Heritage CREhAR in the digital era (Шпанија)

Open House Thessaloniki - Exhibition

HERSUS Project Open House in Thessaloniki took place from the 8th till the 16th of June 2023 with an exhibition open to the public at the Centre for Architecture of the Municipality of Thessaloniki. The exhibition presented the activities and results of HERSUS Project, including six Intelectual Outputs, three International Student Workshops, awarded projects with Prize on Modern Built Heritage, as well as HERSUS international presence and media projection. The HERSUS project proposes enhancing and testing of innovative teaching practices in the field of sustainability of the built heritage and strives to enhance the competence and motivation of educators and researchers to include curricula elements that will have tangible results, preparing students and educators to become real actors of the environmental change.HERSUS Consortium Vladan Djokić, Ana Radivojević, Ana Nikezić, Jelena Živković, Nataša Ćuković Ignjatović, Milica Milojević, Jelena Ristić Trajković, Aleksandra Milovanović, Aleksandra Djordjević, Mladen Pešić, Ana Zorić, Bojana Zeković, Tamara Popović, Nevena Lukić, Emanuela Sorbo, Enrico Anguillari, Sofia Tonello, Irene Sgarro,Maria Philokyprou, Aimilios Michael, Andreas Savvides, Panayiota Pyla, Odysseas Kontovourkis, Stavroula Thravalou, Maria Nodaraki, Theodora Hadjipetrou, Konstantinos Sakantamis, Alkmini Paka, Kleoniki Axarli, Maria Doussi, Angeliki Chatzidimitriou, Sofoklis Kotsopoulos, Mar Loren-Méndez, José Peral López, Enrique Larive, Julia Rey, Marta García de Casasola Gómez, María Carrascal, Daniel Pinzón-Ayala, María Álvarez de los Corrales, Roberto Alonso-Jiménez. Учесници: Архитектонски факултет, Универзитет у Београду (Србија), IUAV University of Venice (Италија), University of Cyprus (Кипар), Aristotle University of Thessaloniki (Грчка), и University of Seville – UNESCO Chair on Built Urban Heritage CREhAR in the digital era (Шпанија)

Open House Nicosia - Exhibition

The UCY HERSUS OPEN HOUSE activity of the International HERSUS project took place at the Department of Architecture of the University of Cyprus (UCy) on June 7th. The exhibition presented the activities and results of HERSUS Project, including (1) Presentation of HERSUS Intellectual Outputs (01: Review of the Best Practices on Educating Sustainability and Heritage, 02: Questionnaire for the State of Art, 03: Statements for Teaching through Design for Sustainability of the Built Environment and Heritage Awareness, 04: HERSUS Sharing Platform) and other activities (timeline of the Hersus outputs, main achievements etc), (2) Results of the three International HERSUS Student Workshops (C2: Student Workshop 1: Sustainable Reconstruction in Urban Areas; C3: Student Workshop 2: Adaptive Reuse; C4: Student Workshop 3: Resilience and Climate Change), (3) Awarded projects of the HERSUS Prize on Modern Built Heritage (awarded finalist and shortlisted proposals for each of the four categories – Education Students, Education Instructors, Practice and Research). The exhibition was held at the Lobby of the UCY Department of Architecture at the same time as the students’ final projects exhibition for the academic year 2022-2023. The event was well attended, with participation and interest by students and faculty, as well as representatives from various municipalities, public entities and of course from practice. Moreover, introductory keynotes for the event were delivered by the university’s Vice-Rector of Academic Affairs, the Vice- Dean of the School of Engineering, the president of the Cyprus Scientific and Technical Chamber, the president of the Cyprus Architects Association and last but by no means least, the UCY Hersus coordinator

HERSUS [Commendation at 44th Salon of Architecture]

HERSUS (Enhancing of Heritage Awareness and Sustainability of Built Environment in Architectural and Urban Design Higher Education) is Erasmus + Strategic Partnerships for higher education which brings together five Universities from Serbia, Italy, Cyprus, Greece, and Spain working together on the design and development of the courses while disseminating knowledge through international training courses, workshops, and a jointly built Sharing Platform