Preparation and charge transport properties of 11-V compounds

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Coherent state transfer between an electron- and nuclear spin in 15N@C60

Electron spin qubits in molecular systems offer high reproducibility and the ability to self assemble into larger architectures. However, interactions between neighbouring qubits are 'always-on' and although the electron spin coherence times can be several hundred microseconds, these are still much shorter than typical times for nuclear spins. Here we implement an electron-nuclear hybrid scheme which uses coherent transfer between electron and nuclear spin degrees of freedom in order to both controllably turn on/off dipolar interactions between neighbouring spins and benefit from the long nuclear spin decoherence times (T2n). We transfer qubit states between the electron and 15N nuclear spin in 15N@C60 with a two-way process fidelity of 88%, using a series of tuned microwave and radiofrequency pulses and measure a nuclear spin coherence lifetime of over 100 ms.Comment: 5 pages, 3 figures with supplementary material (8 pages

DNA as a programmable viscoelastic nanoelement

The two strands of a DNA molecule with a repetitive sequence can pair into many different basepairing patterns. For perfectly periodic sequences, early bulk experiments of Poerschke indicate the existence of a sliding process, permitting the rapid transition between different relative strand positions [Biophys. Chem. 2 (1974) 83]. Here, we use a detailed theoretical model to study the basepairing dynamics of periodic and nearly periodic DNA. As suggested by Poerschke, DNA sliding is mediated by basepairing defects (bulge loops), which can diffuse along the DNA. Moreover, a shear force f on opposite ends of the two strands yields a characteristic dynamic response: An outward average sliding velocity v~1/N is induced in a double strand of length N, provided f is larger than a threshold f_c. Conversely, if the strands are initially misaligned, they realign even against an external force less than f_c. These dynamics effectively result in a viscoelastic behavior of DNA under shear forces, with properties that are programmable through the choice of the DNA sequence. We find that a small number of mutations in periodic sequences does not prevent DNA sliding, but introduces a time delay in the dynamic response. We clarify the mechanism for the time delay and describe it quantitatively within a phenomenological model. Based on our findings, we suggest new dynamical roles for DNA in artificial nanoscale devices. The basepairing dynamics described here is also relevant for the extension of repetitive sequences inside genomic DNA.Comment: 10 pages, 7 figures; final version to appear in Biophysical Journa

Export Coefficient Modelling of Nutrient Neutrality to Protect Aquatic Habitats in the River Wensum Catchment, UK

The pressure of nutrient pollution derived from wastewater treatment works and agricultural runoff is a reason for the decline in the ecological health of aquatic habitats. Projected residential development in catchments creates further nutrient loading that can be offset by nutrient management solutions that maintain ‘nutrient neutrality’ either onsite or elsewhere within the same catchment. This study developed an export coefficient model in conjunction with detailed farm business data to explore a nature-based solution to nutrient neutrality involving seven scenarios of crop conversion to mixed woodland or grazing grass in an area of intensive arable cultivation in the groundwater-fed Blackwater sub-catchment of the River Wensum, UK. When compared with the monitored riverine export of nutrients, the calculated nitrogen (N) and phosphorus (P) inputs under current land use showed that subsurface denitrification is removing 48–78% of the leached N and that P is accumulating in the field soils. The addition of 235 residential homes planned for 2018–2038 in the Blackwater will generate an additional nutrient load of 190 kg N a−1 and 4.9 kg P a−1. In six of the seven scenarios, the modelled fractions of crop conversion (0.02–0.21) resulted in the required reduction in P loading and more than sufficient reduction in N loading (196–1874 kg a−1 for mixed woodland and 287–2103 kg a−1 for grazing grass), with the additional reduction in N load above the requirement for nutrient neutrality potentially contributing to further improvement in water quality. The cost of land conversion is modelled in terms of crop gross margins and nutrient credits generated in the form of 0.1 kg units of N or P. For the range of scenarios considered, the annual cost per credit ranged from GBP 0.78–11.50 for N for mixed woodland (GBP 0.74–7.85 for N for grazing grass) and from GBP 160–782 for P for both scenarios. It is concluded that crop conversion is a viable option to achieve nutrient neutrality in arable catchments in eastern England when considered together with other nutrient management solutions

Assessing the farm-scale impacts of cover crops and non-inversion tillage regimes on nutrient losses from an arable catchment

The efficacy of cover crops and non-inversion tillage regimes at minimising farm-scale nutrient losses were assessed across a large, commercial arable farm in Norfolk, UK. The trial area, covering 143 ha, was split into three blocks: winter fallow with mouldboard ploughing (Block J); shallow non-inversion tillage with a winter oilseed radish (Raphanus sativus) cover crop (Block P); and direct drilling with a winter oilseed radish cover crop (Block L). Soil, water and vegetation chemistry across the trial area were monitored over the 2012/13 (pre-trial), 2013/14 (cover crops and non-inversion tillage) and 2014/15 (non-inversion tillage only) farm years. Results revealed oilseed radish reduced nitrate (NO3¬¬-N) leaching losses in soil water by 75–97% relative to the fallow block, but had no impact upon phosphorus (P) losses. Corresponding reductions in riverine NO3¬¬-N concentrations were not observed, despite the trial area covering 20% of the catchment. Mean soil NO3¬¬-N concentrations were reduced by ~77% at 60–90 cm depth beneath the cover crop, highlighting the ability of deep rooting oilseed radish to scavenge nutrients from deep within the soil profile. Alone, direct drilling and shallow non-inversion tillage were ineffective at reducing soil water NO3¬¬-N and P concentrations relative to conventional ploughing. Applying starter fertiliser to the cover crop increased radish biomass and nitrogen (N) uptake, but resulted in net N accumulation within the soil. There was negligible difference between the gross margins of direct drilling (£731 ha-1) and shallow non-inversion tillage (£758 ha-1) with a cover crop and conventional ploughing with fallow (£745 ha-1), demonstrating farm productivity can be maintained whilst mitigating diffuse pollution. The results presented here support the wider adoption of winter oilseed radish cover crops to reduce NO3¬¬-N leaching losses in arable systems, but caution that it may take several years before catchment-scale impacts downstream are detected

The Ursinus Weekly, November 2, 1972

Election 1972: Vote! • Ecology group gears up truck • The U.C. Student Activities Committee divides eleven thousand dollars • Negative demerit proposal accepted by administration • Specks burns • Halloween dance draws one hundred fifty people, or U.C., the east coast\u27s number one suitcase college • Editorial: The Rot • Spotlight: Cris Crane • Fidler on the wax: Close to the edge • Forum guest Fred Kolb: mentalist or magician? • West Chester vs Ursinus: What a game! • Harriers bounce back! • Won, lost, and tied • Sports buff\u27s cornerhttps://digitalcommons.ursinus.edu/weekly/1090/thumbnail.jp

Application of high-resolution telemetered sensor technology to develop conceptual models of catchment hydrogeological processes

Mitigating agricultural water pollution requires changes in land management practices and the implementation of on-farm measures to tackle the principal reasons for water quality failure. However, a paucity of robust empirical evidence on the hydrological functioning of river catchments can be a major constraint on the design of effective pollution mitigation strategies at the catchment-scale. In this regard, in 2010 the UK government established the Demonstration Test Catchment (DTC) initiative to evaluate the extent to which on-farm mitigation measures can cost-effectively reduce the impacts of agricultural water pollution on river ecology while maintaining food production capacity. A central component of the DTC platform has been the establishment of a comprehensive network of automated, web-based sensor technologies to generate high-temporal resolution empirical datasets of surface water, soil water, groundwater and meteorological parameters. In this paper, we demonstrate how this high-resolution telemetry can be used to improve our understanding of hydrological functioning and the dynamics of pollutant mobilisation and transport under a range of hydrometerological and hydrogeological conditions. Furthermore, we demonstrate how these data can be used to develop conceptual models of catchment hydrogeological processes and consider the implications of variable hydrological functioning on the performance of land management changes aimed at reducing agricultural water pollution

Community Acquired Bacteremia in Young Children from Central Nigeria- A Pilot Study

<p>Abstract</p> <p>Background</p> <p>Reports of the etiology of bacteremia in children from Nigeria are sparse and have been confounded by wide spread non-prescription antibiotic use and suboptimal laboratory culture techniques. We aimed to determine causative agents and underlying predisposing conditions of bacteremia in Nigerian children using data arising during the introduction of an automated blood culture system accessed by 7 hospitals and clinics in the Abuja area.</p> <p>Methods</p> <p>Between September 2008 and November 2009, we enrolled children with clinically suspected bacteremia at rural and urban clinical facilities in Abuja or within the Federal Capital Territory of Nigeria. Blood was cultured using an automated system with antibiotic removing device. We documented clinical features in all children and tested for prior antibiotic use in a random sample of sera from children from each site.</p> <p>Results</p> <p>969 children aged 2 months-5 years were evaluated. Mean age was 21 ± 15.2 months. All children were not systematically screened but there were 59 (6%) children with established diagnosis of sickle cell disease and 42 (4.3%) with HIV infection. Overall, 212 (20.7%) had a positive blood culture but in only 105 (10.8%) were these considered to be clinically significant. Three agents, <it>Staphylococcus aureus </it>(20.9%), <it>Salmonella typhi </it>(20.9%) and Acinetobacter (12.3%) accounted for over half of the positive cultures. <it>Streptococcus pneumoniae and non-typhi Salmonellae </it>each accounted for 7.6%. Although not the leading cause of bacteremia, <it>Streptococcus pneumoniae </it>was the single leading cause of all deaths that occurred during hospitalization and after hospital discharge.</p> <p>Conclusion</p> <p><it>S. typhi </it>is a significant cause of vaccine-preventable morbidity while <it>S. pneumoniae </it>may be a leading cause of mortality in this setting. This observation contrasts with reports from most other African countries where non-typhi Salmonellae are predominant in young children. Expanded surveillance is required to confirm the preliminary observations from this pilot study to inform implementation of appropriate public health control measures.</p