12,803 research outputs found
Automated Network Service Scaling in NFV: Concepts, Mechanisms and Scaling Workflow
Next-generation systems are anticipated to be digital platforms supporting
innovative services with rapidly changing traffic patterns. To cope with this
dynamicity in a cost-efficient manner, operators need advanced service
management capabilities such as those provided by NFV. NFV enables operators to
scale network services with higher granularity and agility than today. For this
end, automation is key. In search of this automation, the European
Telecommunications Standards Institute (ETSI) has defined a reference NFV
framework that make use of model-driven templates called Network Service
Descriptors (NSDs) to operate network services through their lifecycle. For the
scaling operation, an NSD defines a discrete set of instantiation levels among
which a network service instance can be resized throughout its lifecycle. Thus,
the design of these levels is key for ensuring an effective scaling. In this
article, we provide an overview of the automation of the network service
scaling operation in NFV, addressing the options and boundaries introduced by
ETSI normative specifications. We start by providing a description of the NSD
structure, focusing on how instantiation levels are constructed. For
illustrative purposes, we propose an NSD for a representative NS. This NSD
includes different instantiation levels that enable different ways to
automatically scale this NS. Then, we show the different scaling procedures the
NFV framework has available, and how it may automate their triggering. Finally,
we propose an ETSI-compliant workflow to describe in detail a representative
scaling procedure. This workflow clarifies the interactions and information
exchanges between the functional blocks in the NFV framework when performing
the scaling operation.Comment: This work has been accepted for publication in the IEEE
Communications Magazin
Optimized LTE Data Transmission Procedures for IoT: Device Side Energy Consumption Analysis
The efficient deployment of Internet of Things (IoT) over cellular networks,
such as Long Term Evolution (LTE) or the next generation 5G, entails several
challenges. For massive IoT, reducing the energy consumption on the device side
becomes essential. One of the main characteristics of massive IoT is small data
transmissions. To improve the support of them, the 3GPP has included two novel
optimizations in LTE: one of them based on the Control Plane (CP), and the
other on the User Plane (UP). In this paper, we analyze the average energy
consumption per data packet using these two optimizations compared to
conventional LTE Service Request procedure. We propose an analytical model to
calculate the energy consumption for each procedure based on a Markov chain. In
the considered scenario, for large and small Inter-Arrival Times (IATs), the
results of the three procedures are similar. While for medium IATs CP reduces
the energy consumption per packet up to 87% due to its connection release
optimization
A near-IR line of Mn I as a diagnostic tool of the average magnetic energy in the solar photosphere
We report on spectropolarimetric observations of a near-IR line of Mn I
located at 15262.702 A whose intensity and polarization profiles are very
sensitive to the presence of hyperfine structure. A theoretical investigation
of the magnetic sensitivity of this line to the magnetic field uncovers several
interesting properties. The most important one is that the presence of strong
Paschen-Back perturbations due to the hyperfine structure produces an intensity
line profile whose shape changes according to the absolute value of the
magnetic field strength. A line ratio technique is developed from the intrinsic
variations of the line profile. This line ratio technique is applied to
spectropolarimetric observations of the quiet solar photosphere in order to
explore the probability distribution function of the magnetic field strength.
Particular attention is given to the quietest area of the observed field of
view, which was encircled by an enhanced network region. A detailed theoretical
investigation shows that the inferred distribution yields information on the
average magnetic field strength and the spatial scale at which the magnetic
field is organized. A first estimation gives ~250 G for the mean field strength
and a tentative value of ~0.45" for the spatial scale at which the observed
magnetic field is horizontally organized.Comment: 42 pages, 17 figures, accepted for publication in the Astrophysical
Journal. Figures 1 and 9 are in JPG forma
The interaction of aluminum with catecholamine-based neurotransmitters: Can the formation of these species be considered a potential risk factor for neurodegenerative diseases?
The potential neurotoxic role of Al(iii) and its proposed link with the insurgence of Alzheimer's Disease (AD) have attracted increasing interest towards the determination of the nature of bioligands that are propitious to interact with aluminum. Among them, catecholamine-based neurotransmitters have been proposed to be sensitive to the presence of this non-essential metal ion in the brain. In the present work, we characterize several aluminum-catecholamine complexes in various stoichiometries, determining their structure and thermodynamics of formation. For this purpose, we apply a recently validated computational protocol with results that show a remarkably good agreement with the available experimental data. In particular, we employ Density Functional Theory (DFT) in conjunction with continuum solvation models to calculate complexation energies of aluminum for a set of four important catecholamines: l-DOPA, dopamine, noradrenaline and adrenaline. In addition, by means of the Quantum Theory of Atoms in Molecules (QTAIM) and Energy Decomposition Analysis (EDA) we assessed the nature of the Al-ligand interactions, finding mainly ionic bonds with an important degree of covalent character. Our results point at the possibility of the formation of aluminum-catecholamine complexes with favorable formation energies, even when proton/aluminum competition is taken into account. Indeed, we found that these catecholamines are better aluminum binders than catechol at physiological pH, because of the electron withdrawing effect of the positively-charged amine that decreases their deprotonation penalty with respect to catechol. However, overall, our results show that, in an open biological environment, the formation of Al-catecholamine complexes is not thermodynamically competitive when compared with the formation of other aluminum species in solution such as Al-hydroxide, or when considering other endogenous/exogenous Al(iii) ligands such as citrate, deferiprone and EDTA. In summary, we rule out the possibility, suggested by some authors, that the formation of Al-catecholamine complexes in solution might be behind some of the toxic roles attributed to aluminum in the brain. An up-to-date view of the catecholamine biosynthesis pathway with sites of aluminum interference (according to the current literature) is presented. Alternative mechanisms that might explain the deleterious effects of this metal on the catecholamine route are thoroughly discussed, and new hypotheses that should be investigated in future are proposed
Response to fungal exudates of the rhizosphere isolate Pseudomonas sp. UMAF110 involves a GGDEF/EAL domain-containing protein
Pseudomonas sp. UMAF110, isolated from rhizosphere soil in Spain, display in vitro antagonism towards the pythopathogenic fungus Rosellinia necatrix and is able grow in fungal exudates (BM-RE medium). A transposon mutant library of this strain was constructed and several mutants were selected by their reduced competitiveness in BM-RE medium. Pseudomonas sp. UMAF110-G3, which contains the transposon into a gene encoding a putative REC/PAS/GGDEF/EAL protein, was selected for further characterization. Blastn searches using the sequence of the gene interrupted by the transposon in UMAF110-G3, here called cmpA (c-di-GMP Metabolizing Protein), yielded a single positive hit (98% cover, 78% identity) with a gene from a terpene-degrading Pseudomonas sp. strain isolated from soil. Context analysis of the cmpA gene in Pseudomonas sp. UMAF110 showed that this gene is located downstream from several genes involved in flagellar motility/chemotaxis. RT-PCR experiments further confirmed that cmpA form a transcriptional unit with the che gene cluster. Expression analysis of cmpA by qRT-PCR clearly showed upregulation of this gene after transfer of Pseudomonas sp. UMAF110 cells to BM-RE medium, suggesting a role for this operon in response to fungal exudates. Deletion of cmpA in Pseudomonas sp. UMAF110 did not affect the ability of the strain to form biofilms under the conditions tested. However, overexpression of wild type CmpA in Pseudomonas putida KT2440 negatively regulated biofilm formation in this strain. Together, these results suggest that CmpA could be involved in signal transduction pathways regulating flagellar motility/chemotaxis in response to fungal exudates.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech
Radiolysis of the Glycolaldehyde-Na+Montmor- illonite and Glycolaldehyde-Fe3+Montmorillonite Systems in Aqueous Suspension under Gamma Radiation Fields: Implications in Chemical Evolution
The stability and reactivity of organic molecules with biological and pre-biological significance in primitive conditions are of paramount importance in chemical evolution studies. Sugars are an essential component in biological systems for the different roles that they play in living beings. The objective of the present work is to study the gamma radiolysis of aqueous solutions of glycolaldehyde, the simplest sugar and aqueous suspensions of glycolaldehyde-Na+-montmorillonite and glycolaldehyde-Fe3+Montmorillonite. Our results indicate that the radiolysis of the aqueous solutions of glycolaldehyde (0.03M), oxygen free, mainly produce the linear dimer known as eritriol (122 g/mol) and a sugar-like compound with six carbon atoms (180 g/mol). The experiments with the clay suspensions show that clays can adsorb glycolaldehyde and protect it from gamma irradiation. Additionally, it was observed that depending on the cation present in the clay, the percentage and the product (monomer or cyclic dimer) adsorption was different. In the case of Fe3+ Montmorillonite, this clay catalyzed the decomposition of glycolaldehyde, forming small amounts non-identified products. The analysis of these systems was performed by ATR-FTIR, UV spectroscopy, liquid chromatography (UHPLC-UV), and HPLC coupled to a mass spectrometry
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