Heterogeneity Based Solvers’ Segmentation In Crowdsourcing

Multiple facets of factors were examined to be drivers for crowdsourcing intention. However, there is limited research that has studied whether this factors-intention link is uniform for all solvers or not in detail. In fact, the present studies have identified three different segments that are internally consistent and stable. The comparison between the results of two different solutions, single-class and prediction-oriented-segmentation, confirms the existence of unobserved solver segments. The three established segments are “Self-leading solvers”, “External-driving solvers” and “Dual-driving solvers”. These results point the way for factors-based segmentation in intention initiatives and reflect the importance of a multidimensional conceptualization of factors, comprising motivation, perceived sponsor’s and platform’s support components. The paper expands and deepens the application of the heterogeneity theory in the study of crowdsourcing usage behavior and offers implications for organizers to recognize the solvers more clearly and get directions for more valid strategies

Dynamic analysis of reciprocating compressor system with translational clearance and time-varying load

Dynamic behavior of reciprocating compressor system, with translational clearance between the crosshead and guide under time-varying cylinder load, is investigated. In order to analyze the dynamic response of the system with translational clearance, a novel nonlinear dynamic model is established based on the Lagrangian approach. The numerical solution of the dynamic equation is calculated by the Runge-Kutta method. The results show that the translational clearance has a great effect on the reciprocating compressor, and the more the translational clearance, the great the influence. Moreover, the phase space of the crosshead reveals that the reciprocating compressor system with translational clearance has chaotic characteristics

Dynamic analysis of localized defects in rolling bearing systems

In this paper, the dynamics of rolling bearing with localized defects of the outer ring and rolling element are investigated. In order to study the nonlinear dynamical behaviors of the rolling bearing precisely, a novel dynamic model of the rolling bearing is established based on the Lagrangian approach. By setting 0.2 mm, 0.4 mm and 0.6 mm local defects on the outer ring and rolling element of bearing respectively, the results demonstrate that the amplitude of the rolling bearing is more intense as the local defect size increases, and the acceleration amplitude fluctuation is more significant than the velocity. In addition, in the case of the same defect size, the vibration of the rolling element defect is more intense than the vibration response caused by the outer ring defect

Infratentorial superficial siderosis: report of six cases and review of the literature

ObjectivesTo investigate the etiology, clinical manifestations, imaging features, and treatment of patients with infratentorial superficial siderosis (iSS), enhance clinicians' comprehension of this rare disease, and conduct oral deferiprone intervention and subsequent monitoring.MethodsSix patients diagnosed with iSS based on magnetic resonance imaging (MRI) and susceptibility weighted imaging (SWI) were enrolled from 2021 to 2023 at the First Affiliated Hospital of Fujian Medical University. Their clinical datas were summarized, and the etiology and imaging characteristics were analyzed. Follow-up was conducted through telephone or outpatient visits.ResultsAmong the 6 patients, there were 3 males and 3 females. The onset age ranged from 35 to 71 years, with an average onset age of 53 years. The clinical symptoms mainly included acoustic disturbances (6/6), gait imbalance (6/6), dysolfactory (6/6), cognitive impairment (2/6), epilepsy (2/6), and pyramidal tract sign (2/6). Evidence of superficial siderosis was observed on MRI across the cortex, brainstem, cerebellum, and spinal cord in all patients. T2-space sequence MRI revealed two instances of dural tear. During the follow-up period ranging from 1 month to 3 years, three patients who received oral deferiprone treatment showed improvement, whereas the remaining three patients who declined deferiprone treatment demonstrated progression.ConclusionThe primary clinical manifestations of iSS include bilateral sensorineural hearing disturbances, progressive cerebellar ataxia, and spinal cord lesions. The key diagnostic criteria involve the presence of linear hypointensity on T2-WI in the surface region of the nervous system. Dural tear caused by various factors is considered to be the most common cause of iSS, and its treatment mainly involves surgical intervention for hemorrhagic primary diseases as well as pharmacotherapy with deferiprone

Dual circulation strategy, regional healthcare development, and medical collaborative innovation efficiency: evidence from Chinese cities

This study analyzes panel data of Chinese cities from 2003 to 2018 as a sample in the context of the dual circulation strategy in China to ascertain the impact of urban healthcare development on medical collaborative innovation efficiency by using the GS2SLS method. Furthermore, it empirically examines the influence mechanism of regional healthcare development on medical collaborative innovation efficiency by using a threshold regression model. Additionally, we identified the heterogeneity of this impact in different cities. The results show the following: (1) There is a significant positive spatial correlation between regional healthcare development and medical collaborative innovation efficiency; (2) Under the dual circulation strategy, the regional investment level in international circulation has the most significant role in the overall strategy, and domestic circulation has been significantly improved after the launch of the innovation-driven strategy; (3) The results of the threshold test show that while domestic and international circulation promote the efficiency of collaborative innovation by 0.83, the promotion effect is more obvious under a higher regional healthcare development level. The research in this paper can provide specific guidance for the development of China’s healthcare industry under the background of dual-cycle strategy, and can also provide valuable reference for developing countries in the world

Composition and distribution of diatom assemblages in the surface sediments of the Bering Sea

Diatoms collected from the top 1 cm of the surface sediment layer at seven Bering Sea stations during the Fourth Chinese National Arctic Research Expedition (4th CHINARE-Arctic) in 2010 were studied. In total, 101 taxa belonging to 38 genera were found. The species were divided into four groups: eurythermal species, boreal-temperate species, polar species, and sea-ice species. The diatom assemblages at the stations in the southwestern basin area were primarily composed of boreal-temperate species, such as Neodenticula seminae, Thalassiosira trifulta, Rhizosolenia hebetata f. hiemalis, and Actinocyclus curvatulus. The northeastern shelf stations were dominated by polar species, including Fragilariopsis oceanica, Thalassiosira antarctica spora, Thalassiosira nordenskioeldii, and Thalassiosira hyalina. The overall abundance was highest at the basin stations with 3.7 ×106 cells∙g-1 of wet sediment, whereas the eastern shelf stations had the lowest abundance of 0.7×106 cells∙g-1 of wet sediment (excluding the resting spores of Chaetoceros spp.). The relationship between the distribution of the surface sediment diatom assemblages and the environment is discussed

Application of weighted gene co-expression network and immune infiltration for explorations of key genes in the brain of elderly COVID-19 patients

IntroductionAlthough many studies have demonstrated the existing neurological symptoms in COVID-19 patients, the mechanisms are not clear until now. This study aimed to figure out the critical molecular and immune infiltration situations in the brain of elderly COVID-19 patients.MethodsGSE188847 was used for the differential analysis, WGCNA, and immune infiltration analysis. We also performed GO, KEGG, GSEA, and GSVA for the enrich analysis.Results266 DEGs, obtained from the brain samples of COVID-19 and non-COVID-19 patients whose ages were over 70 years old, were identified. GO and KEGG analysis revealed the enrichment in synapse and neuroactive ligand-receptor interaction in COVID-19 patients. Further analysis found that asthma and immune system signal pathways were significant changes based on GSEA and GSVA. Immune infiltration analysis demonstrated the imbalance of CD8+ T cells, neutrophils, and HLA. The MEpurple module genes were the most significantly different relative to COVID-19. Finally, RPS29, S100A10, and TIMP1 were the critical genes attributed to the progress of brain damage.ConclusionRPS29, S100A10, and TIMP1 were the critical genes in the brain pathology of COVID-19 in elderly patients. Our research has revealed a new mechanism and a potential therapeutic target