Efficacy of the combination of Tenghuangjiangu tablets, alfacalcidol capsules and caltrate D3 tablets in osteoporotic vertebral compression fracture, and their effects on bone metabolic indices

Purpose: To investigate the efficacy of the combination of Tenghuangjiangu tablets, Alfacalcidol capsules and Caltrate D3 tablets in osteoporotic vertebral compression fracture (OVCF) and their effects on bone metabolic indices. Methods: Ninety-six patients with OVCF were randomly categorized into study group (SG) and control group (CG). Patients in the CG orally took Caltrate D3 tablets, while those in the SG were given Tenghuangjiangu tablets and Alfacalcidol capsules in addition to caltrate D3 tablets. The Bone mineral density (BMD) values and the treatment efficacy were compared. The levels of bone metabolism markers (PINP, β-CTX, BGP, NBAP), CT and PTH were determined using electrochemiluminescence immunoassay, while Ca2+ levels were assessed using liquid level detection. The incidence of adverse reactions (re-fracture, gastrointestinal reaction, hypotension and abnormal coagulation function) were compared. Results: Treatment efficacy in the SG was 91.67 %, which was significantly higher than that in the CG (81.25 %; p < 0.05). Before treatment, the two groups showed no significant differences in BMD, PINP, β-CTX, BGP, NBAP, Ca2+, CT, and PTH levels (p > 0.05). After treatment, the SG exhibited significantly higher BMD, PINP, BGP, NBAP, Ca2+ and CT levels, and showed lower β-CTX and PTH levels than the CG (p < 0.05). The SG exhibited a significantly lower incidence rate of adverse reactions than that the CG (p < 0.05). Conclusion: The combination of Tenghuangjiangu tablets, Alfacalcidol capsules, and Caltrate D3 tablets, improves bone metabolic indices, bone density and treatment efficacy while reducing the incidence rate of adverse reactions

Layer-by-Layer Self-Assembled Graphene Multilayer Films via Covalent Bonds for Supercapacitor Electrodes

To maximize the utilization of its single-atom thin nature, a facile scheme to fabricate graphene multilayer films via a layer-by-layer self-assembled process was presented. The structure of multilayer films was constructed by covalently bonding graphene oxide (GO) using p-phenylenediamine (PPD) as a covalent cross-linking agent. The assembly process was confirmed to be repeatable and the structure was stable. With the π-π conjugated structure and a large number of spaces in the framework, the graphene multilayer films exhibited excellent electrochemical performance. The uniform ultrathin electrode exhibited a capacitance of 41.71 μF/cm2 at a discharge current of 0.1 μA/cm2, and displayed excellent stability of 88.9 % after 1000 charge-discharge cycles

Dynamics of bouncing convex body

Acknowledgements This work is supported by the National Natural Science Foundation of China (12302015, 12172306, 12172167) and Jiangsu Funding Program for Excellent Postdoctoral Talent .Peer reviewe

A Non-Line-of-Sight Mitigation Method For Indoor Ultra-Wideband Localization With Multiple Walls

Ultra-wideband (UWB) ranging techniques can provide accurate distance measurement under line-of-sight (LOS) conditions. However, various walls and obstacles in indoor non-LOS (NLOS) environments, which obstruct the direct propagation of UWB signals, can generate significant ranging errors. Due to the complex through-wall UWB signal propagation, most conventional studies simplify the ranging error model by assuming that the incidence angle is zero or the relative permittivity\u27s for different walls are the same to improve the through-wall UWB localization performance. Considering walls are different in realistic settings, this article presents a through-multiple-wall NLOS mitigation method for UWB indoor positioning. First, spatial geometric equilibrium equations of UWB through-wall propagation and a numerical method are developed for the precise modeling of UWB through-wall ranging errors. Then, calculated error maps are determined numerically without field measurements. Finally, the determined error maps are combined with a gray wolf optimization algorithm for localization. The proposed method is evaluated via field experiments with four rooms, three walls, and six penetration cases. The results demonstrate that the method can strongly mitigate the multi-wall. NLOS effects on the performance of UWB positioning systems. This solution can reduce project costs and number of power supplies for UWB indoor positioning applications

Development and testing of a XYZ scanner for atomic force microscope

Atomic force microscopy (AFM) is a widely used tool in nano measurement and manipulation techniques. However, a traditional AFM system suffers from the limitation of slow scanning rate, due to the low dynamic performance of piezoelectric positioners. As an important part of AFM system, scanner will have a significant impact the result of the scanning imaging and operation. It is well know that high-speed operation of an AFM are increasingly required, and it is also a challenge for the researchers. In this paper, we proposed a parallel kinematic high-speed piezoelectric actuator (PZT) XYZ scanner. The design is aimed at achieving high resonance frequencies and low cross-coupling. The developed stage consists of a parallel kinematic XY stage and a Z stage. The Z stage is mounted on the central moving platform of the XY stage. To achieve the design objective, several parallel leaf flexure hinge mechanisms, arranging symmetrically around the central moving platform of the XY stage, are utilized to provide large stiffness and reduce cross-coupling. For the Z stage, a symmetrical leaf flexure parallelogram mechanism is adopted to achieve high resonance frequencies and decoupling. Then, finite element analysis (FEA) is utilized to validate the characteristics of the XYZ scanner. Finally, extensive experiments are conducted, demonstrating feasibility of the proposed scanner

Boundedness of solutions for a bouncing ball model with quasiperiodic moving wall

Acknowledgments This work is supported by the National Natural Science Foundation of China (No. 12172306, 12172167).Peer reviewe