Transient dynamics of a one-dimensional Holstein polaron under the influence of an external electric field

Following the Dirac-Frenkel time-dependent variational principle, transient dynamics of a one-dimensional Holstein polaron with diagonal and off-diagonal exciton-phonon coupling in an external electric field is studied by employing the multi-D$_2$ {\it Ansatz}, also known as a superposition of the usual Davydov D$_2$ trial states. Resultant polaron dynamics has significantly enhanced accuracy, and is in perfect agreement with that derived from the hierarchy equations of motion method. Starting from an initial broad wave packet, the exciton undergoes typical Bloch oscillations. Adding weak exciton-phonon coupling leads to a broadened exciton wave packet and a reduced current amplitude. Using a narrow wave packet as the initial state, the bare exciton oscillates in a symmetric breathing mode, but the symmetry is easily broken by weak coupling to phonons, resulting in a non-zero exciton current. For both scenarios, temporal periodicity is unchanged by exciton-phonon coupling. In particular, at variance with the case of an infinite linear chain, no steady state is found in a finite-sized ring within the anti-adiabatic regime. For strong diagonal coupling, the multi-$\rm D_2$ {\it Anstaz} is found to be highly accurate, and the phonon confinement gives rise to exciton localization and decay of the Bloch oscillations

Fine structure and distribution of antennal sensilla of stink bug Arma chinensis (Heteroptera: Pentatomidae)

Scanning electron microscopy was used to examine the morphology, ultrastructure, and distribution of antennal sensilla of the stink bug Arma chinensis. Two types of sensilla trichodea (ST1–2), four types of sensilla basiconica (SB 1– 4), one type of sensilla chaetica (SCH), one type of sensilla cavity (SCA) and one type of sensilla coeloconica (SCO) were distinguished on the antennae in both sexes. ST1 and ST2 were absent from the scape and pedicel. SB1 were absent from the scape. SB2 were distributed throughout the antennae. SB3 were located on the second pedicel and the two flagellomeres. SB4 were absent from the second flagellomere. SCH was observed on the second pedicel and the two flagellomeres. SCA and SCO occurred only on the second flagellomere. SB1 clusters occurred on the distal part of the second flagellomere. We compared the morphology and structure of these sensilla to other Heteroptera and discuss their possible functions

Heparin-binding epidermal growth factor inhibits apoptosis in cisplatin-resistant pancreatic cancer cells via upregulation of EGFR and ERCC 1 expressions

Purpose: To investigate the influence of heparin-binding epidermal growth factor (HB-EGF) on apoptosis in cisplatin-resistant pancreatic cancer cells, as well as its mechanism of action. Methods: Pancreatic cancer cisplatin-resistant cells (BXPC-3/CDDP) were transfected with HB-EGF small interfering RNA (siRNA). The cells were randomly assigned to four groups, namely, BXPC-3 group (group A), BXPC-3/CDDP group (group B), transfected group A (group Asi) and transfected group B (group Bsi). Cell proliferation was determined using MTT assay, and the levels of expression of HBEGF, epidermal growth factor receptor (EGFR) and excision repair cross-complementation group 1 (ERCC 1) were determined using Western blotting. The extent of apoptosis was determined by flow cytometry. Results: Cell proliferation was increased in group B, relative to group A, but was significantly decreased after transfection with HB-EGF siRNA (p < 0.05). The half-maximal inhibitory concentration (IC50) of group Bsi was reduced, relative to group Asi (p < 0.05). The expression of HB-EGF was significantly upregulated in group B, relative to group A (p < 0.05). In contrast, HB-EGF siRNA transfection of the cells significantly down-regulated HB-EGF expression (p < 0.05). Early apoptosis was significantly higher in group A than in groups B and Bsi. Higher levels of apoptosis were seen in group Bsi, relative to group B after inhibition of HB-EGF expression (p < 0.05). Conclusion: These results indicate that HB-EGF is resistant to cisplatin, and it inhibits apoptosis in pancreatic cancer cells via the upregulation of EGFR and ERCC 1 expressions

Dielectric Property of MoS2 Crystal in Terahertz and Visible Region

Two-dimensional materials such as MoS2 have attracted much attention in recent years due to their fascinating optoelectronic properties. Dielectric property of MoS2 is desired for the optoelectronic application. In this paper, terahertz (THz) time-domain spectroscopy and ellipsometry technology are employed to investigate the dielectric response of MoS2 crystal in THz and visible region. The real and imaginary parts of the complex dielectric constant of MoS2 crystal are found to follow a Drude model in THz region, which is due to the intrinsic carrier absorption. In visible region, the general trend of the complex dielectric constant is found to be described with a Lorentz model, while two remarkable peaks are observed at 1.85 and 2.03 eV, which have been attributed to the splitting arising from the combined effect of interlayer coupling and spin-orbit coupling. This work affords the fundamental dielectric data for the future optoelectronic applications with MoS2.Comment: 6 page

Ground state properties of sub-Ohmic spin-boson model with simultaneous diagonal and off-diagonal coupling

By employing the variational approach, density matrix renormalization group (DMRG), exact diagonalization as well as symmetry and mean-field analyses, the ground state properties of the two-bath spin boson model with simultaneous diagonal and off-diagonal coupling are systematically studied in the sub-Ohmic regime. A novel quantum phase transition from a doubly degenerate "localized phase" to the other doubly degenerate "delocalized phase" is uncovered. Via the multi-D1 ansatz as the variational wave function, transition points are determined accurately, consistent with the results from DMRG and exact diagonalization. An effective spatial dimension $d_{eff} = 2.37(6)$ is then estimated, which is found to be compatible with the mean-field prediction. Furthermore, the quantum phase transition is inferred to be of first order for the baths described by a continuous spectral density function. In the case of single mode, however, the transition is softened.Comment: revised version after the paper is publishe

Electrical contact properties between Yb and few-layer WS2_2

Charge injection mechanism from contact electrodes into two-dimensional (2D) dichalcogenides is an essential topic for exploiting electronics based on 2D channels, but remains not well understood. Here, low-work-function metal ytterbium (Yb) was employed as contacts for tungsten disulfide (WS$_2$) to understand the realistic injection mechanism. The contact properties in WS$_2$ with variable temperature (T) and channel thickness (tch) were synergetically characterized. It is found that the Yb/WS$_2$ interfaces exhibit a strong pinning effect between energy levels and a low contact resistance (R_\rm{C}) value down to $5\,k\Omega\cdot\mu$m. Cryogenic electrical measurements reveal that R_\rm{C} exhibits weakly positive dependence on T till 77 K, as well as a weakly negative correlation with tch. In contrast to the non-negligible R_\rm{C} values extracted, an unexpectedly low effective thermal injection barrier of 36 meV is estimated, indicating the presence of significant tunneling injection in subthreshold regime and the inapplicability of the pure thermionic emission model to estimate the height of injection barrier

ConvKyber: Unleashing the Power of AI Accelerators for Faster Kyber with Novel Iteration-based Approaches

The remarkable performance capabilities of AI accelerators offer promising opportunities for accelerating cryptographic algorithms, particularly in the context of lattice-based cryptography. However, current approaches to leveraging AI accelerators often remain at a rudimentary level of implementation, overlooking the intricate internal mechanisms of these devices. Consequently, a significant number of computational resources is underutilized. In this paper, we present a comprehensive exploration of NVIDIA Tensor Cores and introduce a novel framework tailored specifically for Kyber. Firstly, we propose two innovative approaches that efficiently break down Kyber\u27s NTT into iterative matrix multiplications, resulting in approximately a 75% reduction in costs compared to the state-of-the-art scanning-based methods.Secondly, by reversing the internal mechanisms, we precisely manipulate the internal resources of Tensor Cores using assembly-level code instead of inefficient standard interfaces, eliminating memory accesses and redundant function calls. Finally, building upon our highly optimized NTT, we provide a complete implementation for all parameter sets of Kyber. Our implementation surpasses the state-of-the-art Tensor Core based work, achieving remarkable speed-ups of 1.93x, 1.65x, 1.22x and 3.55x for polyvec_ntt, KeyGen, Enc and Dec in Kyber-1024, respectively. Even when considering execution latency, our throughput-oriented full Kyber implementation maintains an acceptable execution latency. For instance, the execution latency ranges from 1.02 to 5.68 milliseconds for Kyber-1024 on R3080 when achieving the peak throughput

ConvKyber: Unleashing the Power of AI Accelerators for Faster Kyber with Novel Iteration-based Approaches

The remarkable performance capabilities of AI accelerators offer promising opportunities for accelerating cryptographic algorithms, particularly in the context of lattice-based cryptography. However, current approaches to leveraging AI accelerators often remain at a rudimentary level of implementation, overlooking the intricate internal mechanisms of these devices. Consequently, a significant number of computational resources is underutilized. In this paper, we present a comprehensive exploration of NVIDIA Tensor Cores and introduce a novel framework tailored specifically for Kyber. Firstly, we propose two innovative approaches that efficiently break down Kyber’s NTT into iterative matrix multiplications, resulting in approximately a 75% reduction in costs compared to the state-of-the-art scanning-based methods. Secondly, by reversing the internal mechanisms, we precisely manipulate the internal resources of Tensor Cores using assembly-level code instead of inefficient standard interfaces, eliminating memory accesses and redundant function calls. Finally, building upon our highly optimized NTT, we provide a complete implementation for all parameter sets of Kyber. Our implementation surpasses the state-of-the-art Tensor Core based work, achieving remarkable speed-ups of 1.93x, 1.65x, 1.22x and 3.55x for polyvec_ntt, KeyGen, Enc and Dec in Kyber-1024, respectively. Even when considering execution latency, our throughput-oriented full Kyber implementation maintains an acceptable execution latency. For instance, the execution latency ranges from 1.02 to 5.68 milliseconds for Kyber-1024 on R3080 when achieving the peak throughput

Epimorphin Regulates Bile Duct Formation via Effects on Mitosis Orientation in Rat Liver Epithelial Stem-Like Cells

Understanding how hepatic precursor cells can generate differentiated bile ducts is crucial for studies on epithelial morphogenesis and for development of cell therapies for hepatobiliary diseases. Epimorphin (EPM) is a key morphogen for duct morphogenesis in various epithelial organs. The role of EPM in bile duct formation (DF) from hepatic precursor cells, however, is not known. To address this issue, we used WB-F344 rat epithelial stem-like cells as model for bile duct formation. A micropattern and a uniaxial static stretch device was used to investigate the effects of EPM and stress fiber bundles on the mitosis orientation (MO) of WB cells. Immunohistochemistry of liver tissue sections demonstrated high EPM expression around bile ducts in vivo. In vitro, recombinant EPM selectively induced DF through upregulation of CK19 expression and suppression of HNF3α and HNF6, with no effects on other hepatocytic genes investigated. Our data provide evidence that EPM guides MO of WB-F344 cells via effects on stress fiber bundles and focal adhesion assembly, as supported by blockade EPM, β1 integrin, and F-actin assembly. These blockers can also inhibit EPM-induced DF. These results demonstrate a new biophysical action of EPM in bile duct formation, during which determination of MO plays a crucial role