8,226 research outputs found
Melting-freezing cycles in a relatively sheared pair of crystalline monolayers
The nonequilibrium dynamical behaviour that arises when two ordered
two-dimensional monolayers of particles are sheared over each other is studied
in Brownian dynamics simulations. A curious sequence of nonequilibrium states
is observed as the driving rate is increased, the most striking of which is a
sliding state with irregular alternation between disordered and ordered states.
We comment on possible mechanisms underlying these cycles, and experiments that
could observe them.Comment: 7 pages, 8 figures, minor changes in text and figures, references
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Adherence to Nutrition and Physical Activity Cancer Prevention Guidelines and Development of Colorectal Adenoma.
Adherence to the American Cancer Society's (ACS) Nutrition and Physical Activity Cancer Prevention Guidelines is associated with reductions in overall cancer incidence and mortality, including site-specific cancers such as colorectal cancer. We examined the relationship between baseline adherence to the ACS guidelines and (1) baseline adenoma characteristics and (2) odds of recurrent colorectal adenomas over 3 years of follow-up. Cross-sectional and prospective analyses with a pooled sample of participants from the Wheat Bran Fiber (n = 503) and Ursodeoxycholic Acid (n = 854) trials were performed. A cumulative adherence score was constructed using baseline self-reported data regarding body size, diet, physical activity and alcohol consumption. Multivariable logistic regression demonstrated significantly reduced odds of having three or more adenomas at baseline for moderately adherent (odds ratio [OR] = 0.67, 95% confidence intervals [CI]: 0.46⁻0.99) and highly adherent (OR = 0.50, 95% CI: 0.31⁻0.81) participants compared to low adherers (p-trend = 0.005). Conversely, guideline adherence was not associated with development of recurrent colorectal adenoma (moderate adherence OR = 1.16, 95% CI: 0.85⁻1.59, high adherence OR = 1.23, 95% CI: 0.85⁻1.79)
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Genetic Variation in Spatio-Temporal Confined USA300 Community-Associated MRSA Isolates: A Shift from Clonal Dispersion to Genetic Evolution?
NTRODUCTION: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) are increasingly isolated, with USA300-0114 being the predominant clone in the USA. Comparative whole genome sequencing of USA300 isolates collected in 2002, 2003 and 2005 showed a limited number of single nucleotide polymorphisms and regions of difference. This suggests that USA300 has undergone rapid clonal expansion without great genomic diversification. However, whole genome comparison of CA-MRSA has been limited to isolates belonging to USA300. The aim of this study was to compare the genetic repertoire of different CA-MRSA clones with that of HA-MRSA from the USA and Europe through comparative genomic hybridization (CGH) to identify genetic clues that may explain the successful and rapid emergence of CA-MRSA.
MATERIALS AND METHODS: Hierarchical clustering based on CGH of 48 MRSA isolates from the community and nosocomial infections from Europe and the USA revealed dispersed clustering of the 19 CA-MRSA isolates. This means that these 19 CA-MRSA isolates do not share a unique genetic make-up. Only the PVL genes were commonly present in all CA-MRSA isolates. However, 10 genes were variably present among 14 USA300 isolates. Most of these genes were present on mobile elements.
CONCLUSION: The genetic variation present among the 14 USA300 isolates is remarkable considering the fact that the isolates were recovered within one month and originated from a confined geographic area, suggesting continuous evolution of this clone
Pathways into services for offenders with intellectual disabilities : childhood experience, diagnostic information and offence variables
The patterns and pathways into intellectual disability (ID) offender services were studied through case file review for 477 participants referred in one calendar year to community generic, community forensic, and low, medium, and maximum secure services. Data were gathered on referral source, demographic information, index behavior, prior problem behaviors, diagnostic information, and abuse or deprivation. Community referrers tended to refer to community services and secure service referrers to secure services. Physical and verbal violence were the most frequent index behaviors, whereas contact sexual offenses were more prominent in maximum security. Age at first incident varied with security, with the youngest in maximum secure services. Attention-deficit/hyperactivity disorder or conduct disorder was the most frequently recorded diagnosis, and severe deprivation was the most frequent adverse developmental experience. Fire starting, theft, and road traffic offenses did not feature prominently. Generic community services accepted a number of referrals with forensic-type behavior and had higher proportions of both women and people with moderate or severe ID
One Dimensional Kondo Lattice Model Studied by the Density Matrix Renormalization Group Method
Recent developments of the theoretical investigations on the one-dimensional
Kondo lattice model by using the density matrix renormalization group (DMRG)
method are discussed in this review. Short summaries are given for the
zero-temperature DMRG, the finite-temperature DMRG, and also its application to
dynamic quantities. Away from half-filling, the paramagnetic metallic state is
shown to be a Tomonaga-Luttinger liquid with the large Fermi surface. For the
large Fermi surface its size is determined by the sum of the densities of the
conduction electrons and the localized spins. The correlation exponent K_rho of
this metallic phase is smaller than 1/2. At half-filling the ground state is
insulating. Excitation gaps are different depending on channels, the spin gap,
the charge gap and the quasiparticle gap. Temperature dependence of the spin
and charge susceptibilities and specific heat are discussed. Particularly
interesting is the temperature dependence of various excitation spectra, which
show unusual properties of the Kondo insulators.Comment: 18 pages, 23 Postscript figures, REVTe
On a conjecture about Dirac's delta representation using q-exponentials
A new representation of Dirac's delta-distribution, based on the so-called
q-exponentials, has been recently conjectured. We prove here that this
conjecture is indeed valid
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