3,430 research outputs found

    Passive Rotation Joint Design Considerations for Lift and Thrust Generation for a Biomimetic Flapping Wing

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    Maximizing the available lift and thrust force is important for designing efficient flapping wing micro air vehicles. Research to date showed the passive rotation joint between the wing and four-bar linkage is an important design aspect. Two key hinge parameters are the angle of attack stop and passive rotation joint stiffness. In this work these design parameters were independently varied. Their impact on lift and thrust force generation, and the ratio of the first and second system resonance frequencies were measured and compared through experiments utilizing prototype hardware of varying design. The prototype hardware and flapping wing controller is based on previous work, focused on using biomimetic wings combined with a design that only requires two piezoelectric actuators, and will be briefly reviewed. The angle of attack stops tested were 30°, 40°, 45°, 50°, and 60°. Five different passive rotation joints were tested of varying stiffness. Optimal angle of attack stops and passive rotation joint designs were found from the experimental results and combined into a best design, which was tested and compared to the optimal results from the independent designs. Results show that while individual selection of angle stop and passive rotation joint stiffness can be optimized, the intersection between the two precludes simply choosing the best of both as the best combined

    A programming logic for Java bytecode programs

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    One significant disadvantage of interpreted bytecode languages, such as Java, is their low execution speed in comparison to compiled languages like C. The mobile nature of bytecode adds to the problem, as many checks are necessary to ensure that downloaded code from untrusted sources is rendered as safe as possible. But there do exist ways of speeding up such systems. One approach is to carry out static type checking at load time, as in the case of the Java Bytecode Verifier. This reduces the number of runtime checks that must be done and also allows certain instructions to be replaced by faster versions. Another approach is the use of a Just In Time (JIT) Compiler, which takes the bytecode and produces corresponding native code at runtime. Some JIT compilers also carry out some code optimization. There are, however, limits to the amount of optimization that can safely be done by the Verifier and JITs; some operations simply cannot be carried out safely without a certain amount of runtime checking. But what if it were possible to prove that the conditions the runtime checks guard against would never arise in a particular piece of code? In this case it might well be possible to dispense with these checks altogether, allowing optimizations not feasible at present. In addition to this, because of time constraints, current JIT compilers tend to produce acceptable code as quickly as possible, rather than producing the best code possible. By removing the burden of analysis from them it may be possible to change this. We demonstrate that it is possible to define a programming logic for bytecode programs that allows the proof of bytecode programs containing loops. The instructions available to use in the programs are currently limited, but the basis is in place to extend these. The development of this logic is non-trivial and addresses several difficult problems engendered by the unstructured nature of bytecode programs

    Constitutive modeling for isotropic materials (HOST)

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    The results of the third year of work on a program which is part of the NASA Hot Section Technology program (HOST) are presented. The goals of this program are: (1) the development of unified constitutive models for rate dependent isotropic materials; and (2) the demonstration of the use of unified models in structural analyses of hot section components of gas turbine engines. The unified models selected for development and evaluation are those of Bodner-Partom and of Walker. A test procedure was developed for assisting the generation of a data base for the Bodner-Partom model using a relatively small number of specimens. This test procedure involved performing a tensile test at a temperature of interest that involves a succession of strain-rate changes. The results for B1900+Hf indicate that material constants related to hardening and thermal recovery can be obtained on the basis of such a procedure. Strain aging, thermal recovery, and unexpected material variations, however, preluded an accurate determination of the strain-rate sensitivity parameter is this exercise. The effects of casting grain size on the constitutive behavior of B1900+Hf were studied and no particular grain size effect was observed. A systematic procedure was also developed for determining the material constants in the Bodner-Partom model. Both the new test procedure and the method for determining material constants were applied to the alternate material, Mar-M247 . Test data including tensile, creep, cyclic and nonproportional biaxial (tension/torsion) loading were collected. Good correlations were obtained between the Bodner-Partom model and experiments. A literature survey was conducted to assess the effects of thermal history on the constitutive behavior of metals. Thermal history effects are expected to be present at temperature regimes where strain aging and change of microstructure are important. Possible modifications to the Bodner-Partom model to account for these effects are outlined. The use of a unified constitutive model for hot section component analyses was demonstrated by applying the Walker model and the MARC finite-element code to a B1900+Hf airfoil problem

    Intensifying rehabilitation of combined sewer systems using trenchless technology in combination with low impact development and green infrastructure

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    Throughout Europe, there is a considerable need for investment in the upgrade of sewer systems – due to three main factors: ageing infrastructure, climate change and urban population growth. The need for investments is expected to grow significantly in the years ahead. Trenchless rehabilitation (no-dig) of sewer pipelines is a cost-efficient and environmental friendly method for upgrading existing pipelines with sufficient capacity. This study examines the possibility of applying no-dig to combined sewer systems (CS) with insufficient capacity. In this study, a concept assessment methodology that combines the analytical approaches from stormwater and sewer system assessments is presented. The methodology was tested on a case area that was part of an environmental project in Oslo, Norway. Three alternative concepts were examined; A0: no-dig and low impact development (LID), A1: no-dig, LID and green infrastructure (GI), and A2: CS up-sizing using open-cut methods. The study concludes that CS with insufficient capacity can be rehabilitated using no-dig if LID and GI. The combination of no-dig and LID reduces costs considerably but does involve the risk of damages from uncontrolled surface runoff. The main risk-reduction measure is the development of GI as an integrated stormwater management system that requires cross-sector collaboration within municipalities.publishedVersio

    Involvement of cyclin-dependent kinase-5 in the kainic acid-mediated degeneration of glutamatergic synapses in the rat hippocampus

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    Increased levels of glutamate causing excitotoxic damage accompany neurological disorders such as ischemia/stroke, epilepsy and some neurodegenerative diseases. Cyclin-dependent kinase-5 (Cdk5) is important for synaptic plasticity and is deregulated in neurodegenerative diseases. However, the mechanisms by which kainic acid (KA)-induced excitotoxic damage involves Cdk5 in neuronal injury are not fully understood. In this work, we have thus studied involvement of Cdk5 in the KA-mediated degeneration of glutamatergic synapses in the rat hippocampus. KA induced degeneration of mossy fiber synapses and decreased glutamate receptor (GluR)6/7 and post-synaptic density protein 95 (PSD95) levels in rat hippocampus in vivo after intraventricular injection of KA. KA also increased the cleavage of Cdk5 regulatory protein p35, and Cdk5 phosphorylation in the hippocampus at 12\u2003h after treatment. Studies with hippocampal neurons in\u2003vitro showed a rapid decline in GluR6/7 and PSD95 levels after KA treatment with the breakdown of p35 protein and phosphorylation of Cdk5. These changes depended on an increase in calcium as shown by the chelators 1,2-bis(o-aminophenoxy)ethane-N,N,N\u200a',N'-tetraacetic acid acetoxymethyl ester (BAPTA-AM) and glycol-bis (2-aminoethylether)-N,N,N\u200a',N\u200a'-tetra-acetic acid. Inhibition of Cdk5 using roscovitine or employing dominant-negative Cdk5 and Cdk5 silencing RNA constructs counteracted the decreases in GluR6/7 and PSD95 levels induced by KA in hippocampal neurons. The dominant-negative Cdk5 was also able to decrease neuronal degeneration induced by KA in cultured neurons. The results show that Cdk5 is essentially involved in the KA-mediated alterations in synaptic proteins and in cell degeneration in hippocampal neurons after an excitotoxic injury. Inhibition of pathways activated by Cdk5 may be beneficial for treatment of synaptic degeneration and excitotoxicity observed in various brain diseases

    Exploring cosmic origins with CORE : Extragalactic sources in cosmic microwave background maps

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    We discuss the potential of a next generation space-borne Cosmic Microwave Background (CMB) experiment for studies of extragalactic sources. Our analysis has particular bearing on the definition of the future space project, CORE, that has been submitted in response to ESA's call for a Medium-size mission opportunity as the successor of the Planck satellite. Even though the effective telescope size will be somewhat smaller than that of Planck, CORE will have a considerably better angular resolution at its highest frequencies, since, in contrast with Planck, it will be diffraction limited at all frequencies. The improved resolution implies a considerable decrease of the source confusion, i.e. substantially fainter detection limits. In particular, CORE will detect thousands of strongly lensed high-z galaxies distributed over the full sky. The extreme brightness of these galaxies will make it possible to study them, via follow-up observations, in extraordinary detail. Also, the CORE resolution matches the typical sizes of high-z galaxy proto-clusters much better than the Planck resolution, resulting in a much higher detection efficiency; these objects will be caught in an evolutionary phase beyond the reach of surveys in other wavebands. Furthermore, CORE will provide unique information on the evolution of the star formation in virialized groups and clusters of galaxies up to the highest possible redshifts. Finally, thanks to its very high sensitivity, CORE will detect the polarized emission of thousands of radio sources and, for the first time, of dusty galaxies, at mm and sub-mm wavelengths, respectively.Peer reviewe

    Collisional perturbation of radio-frequency E1 transitions in an atomic beam of dysprosium

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    We have studied collisional perturbations of radio-frequency (rf) electric-dipole (E1) transitions between the nearly degenerate opposite-parity levels in atomic dysprosium (Dy) in the presence of 10 to 80 ÎĽ\muTorr of H2_\text{2}, N2_\text{2}, He, Ar, Ne, Kr, and Xe. Collisional broadening and shift of the resonance, as well as the attenuation of the signal amplitude are observed to be proportional to the foreign-gas density with the exception of H2_2 and Ne, for which no shifts were observed. Corresponding rates and cross sections are presented. In addition, rates and cross sections for O2_2 are extracted from measurements using air as foreign gas. The primary motivation for this study is the need for accurate determination of the shift rates, which are needed in a laboratory search for the temporal variation of the fine-structure constant [A. T. Nguyen, D. Budker, S. K. Lamoreaux, and J. R. Torgerson, Phys. Rev. A \textbf{69}, 22105 (2004)].Comment: 11 pages, 8 figure

    Arginine-enriched oral nutritional supplementation in the treatment of pressure ulcers: A literature review

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    Abstract Purpose Pressure ulcers are a common, potentially mortal complication to disease, care and treatment for patients of all ages with mobility impairments. In addition, pressure ulcers not always heal straightforward because of multiple intrinsic factors e.g. undernutrition and extrinsic factors e.g. inadequate nutrition that may influence the healing process. The aim of this descriptive review is to investigate the treatment effect of arginine-enriched oral nutritional supplementation in pressure ulcers. Results The included studies, seven RCTs and four CTs, were published between January 2001 and October 2015, and conducted in different settings: hospital, long-term care/care homes and home care. The duration of follow-up of the studies varied from 2 weeks to complete healing and the sample size varied from 16 to 245 patients aged from 37 to 92 years and with pressure ulcer stages II, III or IV. The wound-specific oral nutritional supplementation contained 3–9 g of arginine. The main outcome measures were complete healing, time needed for complete wound closure, reduction in wound surface area, nursing time, and the number of dressings used. Ten out of eleven studies showed a beneficial effect of the arginine-enriched oral nutritional supplementation on the healing of pressure ulcers. Conclusions This review shows that there is substantial evidence supporting the positive effect of nutritional supplementation with additional protein, arginine and micronutrients to promote pressure ulcer healing. Currently, there is only one large study (N = 200) with level 1 evidence. It may be postulated that at least one extra comparable level 1 study is needed to draw firm conclusions on the importance of key nutrients in complete pressure ulcer healing

    Pursuing Regional Opportunities for Mentoring, Innovation, and Success for English Learners (PROMISE) Initiative: A Three-Year Pilot Study Research Monograph

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    The Pursuing Regional Opportunities for Mentoring, Innovation, and Success for English Learners (PROMISE) Initiative Research Monograph is comprised of four sub-studies that took place between 2006 and 2009 to examine the effectiveness of the PROMISE Initiative across six implementing counties. Beginning in 2002, the superintendents of the six Southern California County Offices of Education collaborated to examine the pattern of the alarmingly low academic performance of English learners (EL) across Los Angeles, Orange, San Bernardino, San Diego, Riverside, and Ventura. Together, these six counties serve over one million EL students, more than 66% of the total EL population in the state of California, and close to 20% of the EL population in the nation. Data were compiled for the six counties, research on effective programs for ELs was shared, and a common vision for the success of ELs began to emerge. Out of this effort, the PROMISE Initiative was created to uphold a critical vision that ensured that ELs achieved and sustained high levels of proficiency, high levels of academic achievement, sociocultural and multicultural competency, preparation for successful transition to higher education, successful preparation as a 21st century global citizen, and high levels of motivation, confidence, and self-assurance. This report is organized into six chapters: an introductory chapter, four chapters of related studies, and a summary chapter. The four studies were framed around four areas of inquiry: 1) What is the PROMISE model? 2) What does classroom implementation of the PROMISE model look like? 3) What leadership skills do principals at PROMISE schools need to lead transformative education for ELs? 4) What impact did PROMISE have on student learning and participation? Key findings indicate that the PROMISE Initiative: resulted in positive change for ELs at all levels including achievement gains and narrowing of the gap between ELs and non-ELs increased use of research-based classroom practices refined and strengthened plans for ELs at the district-level, and demonstrated potential to enable infrastructure, partnerships, and communities of practice within and across the six school districts involved. The final chapter of the report provides implications for school reform for improving EL outcomes including bolstering EL expertise in school reform efforts, implementing sustained and in-depth professional development, monitoring and supporting long-term reform efforts, and establishing partnerships and networks to develop, research and disseminate efforts.https://digitalcommons.lmu.edu/ceelreports/1001/thumbnail.jp
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