6 research outputs found
Assessing the photometric redshift precision of the S-PLUS survey: The Stripe-82 as a test-case
Indexación ScopusIn this paper we present a thorough discussion about the photometric redshift (photo-z) performance of the Southern Photometric Local Universe Survey (S-PLUS). This survey combines a seven narrow +5 broad passband filter system, with a typical photometric-depth of r ∼ 21 AB. For this exercise, we utilize the Data Release 1 (DR1), corresponding to 336 deg2 from the Stripe-82 region. We rely on the BPZ2 code to compute our estimates, using a new library of SED models, which includes additional templates for quiescent galaxies. When compared to a spectroscopic redshift control sample of ∼100 k galaxies, we find a precision of σz <0.8 per cent, <2.0 per cent, or <3.0 per cent for galaxies with magnitudes r < 17, <19, and <21, respectively. A precision of 0.6 per cent is attained for galaxies with the highest Odds values. These estimates have a negligible bias and a fraction of catastrophic outliers inferior to 1 per cent. We identify a redshift window (i.e. 0.26 < z < 0.32) where our estimates double their precision, due to the simultaneous detection of two emission lines in two distinct narrow bands; representing a window opportunity to conduct statistical studies such as luminosity functions. We forecast a total of ∼2 M, ∼16 M and ∼32 M galaxies in the S-PLUS survey with a photo-z precision of σz <1.0 per cent, <2.0 per cent, and <2.5 per cent after observing 8000 deg2. We also derive redshift probability density functions, proving their reliability encoding redshift uncertainties and their potential recovering the n(z) of galaxies at z < 0.4, with an unprecedented precision for a photometric survey in the Southern hemisphere. © 2020 The Author(s)https://academic-oup-com.recursosbiblioteca.unab.cl/mnras/article/499/3/3884/585601
Hydrogels containing budesonide-loaded nanoparticles to facilitate percutaneous absorption for atopic dermatitis treatment applications
Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disorder characterized by intense itching and recurrent eczematous lesions. Topical corticosteroids are the first-line treatment to control moderate-to-severe AD; however, prolonged application of corticosteroids is required, which can result in dermal atrophy as a side effect. Drug-delivery systems can provide more effective and targeted therapy strategies. In this study, budesonide (BUD) was encapsulated into chitosan (CS)-coated PLGA nanoparticles, which were further incorporated into poloxamer hydrogels to improve the anti-inflammatory activity and decrease adverse effects. The nanoparticles were prepared by the emulsification–solvent evaporation technique, and their physicochemical characteristics were evaluated. Rheological properties of the hydrogels, such as viscosity and sol–gel transition temperature, were evaluated with and without nanoparticles. In vitro release kinetics and ex vivo drug absorption studies were performed using Franz diffusion cells. The nanoparticles showed a mean diameter of 324 ± 4 nm, positive ζ potential (20 mV) due to CS coating, and high encapsulation efficiency (>90%). The nanoparticles did not show cytotoxic effects in primary human fibroblasts and keratinocytes; however, all formulations induced the generation of reactive oxygen species. Both nanoparticles and hydrogels were able to change the release kinetics of BUD when compared to the nonencapsulated compound. Nanoparticles were not able to surmount the stratum corneum of excised human skin, but the nanoencapsulation facilitated the skin absorption of BUD. The hydrogels containing nanoparticles or not showed non-Newtonian and pseudoplastic behavior. The nanoformulations seem to be a good candidate to deliver glucocorticoids in the skin of AD patients
Quantification Of Antimony In Brazilian Polyethylene Terephthalate (pet) Bottles By X-ray Fluorescence And Chemometric Evaluation To Verify The Presence Of Recycled Pet Through Iron Content. [quantificação De Antimônio Em Garrafas De Politereftalato De Etileno (pet) Brasileiras Por Fluorescência De Raios-x E Avaliação Quimiométrica Para Verificar A Presença De Pet Reciclado Através Do Teor De Ferro]
Antimony is a common catalyst in the synthesis of polyethylene terephthalate used for food-grade bottles manufacturing. However, antimony residues in final products are transferred to juices, soft drinks or water. The literature reports mentions of toxicity associated to antimony. In this work, a green, fast and direct method to quantify antimony, sulfur, iron and copper, in PET bottles by X-ray fluorescence spectrometry is presented. 2.4 to 11 mg Sb kg-1 were found in 20 samples analyzed. The coupling of the multielemental technique to chemometric treatment provided also the possibility to classify PET samples between bottle-grade PET/ recycled PET blends by Fe content.34813891393Romão, W., Spinacé, M.A.S., De Paoli, M.-A., (2009) Polim.: Ciência e Tecnol., 19, p. 121Cadore, S., Matoso, E., Santos, M.C., (2008) Quim. Nova, 31, p. 1533Pereira, R.C.C., MacHado, A.H., Silva, G.G., (2002) Química Nova Na Escola, (15), p. 3Biros, S.M., Bridgewater, B.M., Villeges-Estrada, A., Tanski, J.M., Parkin, G., (2002) Inorg. Chem., 41, p. 4051Romão, W., Franco, M.F., Bueno, M.I.M.S., Eberlin, M.N., De Paoli, M.-A., (2010) J. Appl. Polym. Sci., 117, p. 2993Aharoni, S.M., (1998) Polym. Eng. Sci., 38, p. 1039Martin, R.R., Shotyk, W.S., Naftel, S.J., Ablettc, J.M., Northrupd, P., (2010) X-Ray Spectrom., 39, p. 257Hansen, C., Tsirigotaki, A., Bak, S.A., Pergantis, S.A., Stürup, S., Gammelgaarda, B., Hansena, H.R., (2010) J. Environ. Monit., 12, p. 822Shotyk, W., Krachler, M., Chen, B., (2006) J. Environ. Monit., 8, p. 288Demicheli, C., Frézard, F., (2005) Química Nova Na Escola, (6), p. 24King, R.B., (2005) Encyclopedia of Inorganic Chemistry, , 2nd ed. Wiley: New YorkShotyk, W., Krachler, M., (2007) Environ. Sci. Technol., 41, p. 1560Westerhoff, P., Prapaipong, P., Shock, E., Hillaireau, A., (2008) Water Res., 42, p. 551Skoog, D., Holler, F.J., Nieman, T.A., (1998) Principles of Instrumental Analysis, , 5th ed. Saunders College: Philadelphi