Single nucleotide polymorphisms (SNPs) in genes related to innate immune response against Salmonella in nursery pigs

The objective of this study was to investigate the association of single nucleotide polymorphisms (SNPs) in innate immune response genes with Salmonella shedding in nursery pigs. One hundred and sixty eight pigs on seven farrow-to- finish farms and one farrow-feeder operation were included in the study. On each farm, 21 pigs were selected from seven sows at weaning. Fecal samples were collected from selected pigs and cultured for Salmonella, and the isolates were serotyped. DNA was extracted from liver samples and used to genotype pigs for single nucleotide polymorphisms (SNPs) in 21 different innate immune response genes. In total, 15 (9.3%) pigs tested positive for Salmonella; the isolates from six pigs from four different litters on one farm were serotyped as Salmonella Infantis and from nine pigs from six different litters on another farm as Salmonella Worthington. SNP analysis showed an association of Salmonella shedding with a SNP in the genes encoding mannan-binding lectin (MBL)-associated serine protease-2 (MASP-2) and Toll-like receptor-1 (TLR-1) (P \u3c 0.05). These findings suggest that Salmonella shedding in pigs is controlled by genetic elements and these genetic variants could possibly be used to breed pigs that are more resistant to Salmonella colonization and Salmonella shedding

Charged Lepton Flavor Physics and Extra Dimensions

We estimate the charged lepton electric dipole moments and the branching ratios of radiative lepton flavor violating decays in the framework of the two Higgs doublet model with the inclusion two extra dimensions. Here, we consider that the new Higgs doublet is accessible to one of the extra dimensions with a Gaussian profile and the fermions are accessible to the other extra dimension with uniform zero mode profile. We observe that the numerical values of the physical quantities studied enhance with the additional effects due to the extra dimensions and they are sensitive to the new Higgs localization.Comment: 23 pages, 13 page

Top Compositeness at the Tevatron and LHC

We explore the possibility that the right-handed top quark is composite. We examine the consequences that compositeness would have on $t \bar{t}$ production at the Tevatron, and derive a weak constraint on the scale of compositeness of order a few hundred GeV from the $t \bar{t}$ inclusive cross section. More detailed studies of differential properties of $t \bar{t}$ production could potentially improve this limit. We find that a composite top can result in an enhancement of the $t \bar{t} t \bar{t}$ production rate at the LHC (of as much as $10^3$ compared to the Standatd Model four top rate). We explore observables which allow us to extract the four top rate from the backgrounds, and show that the LHC can either discover or constrain top compositeness for wide ranges of parameter space.Comment: 9 pages, 4 figure

Spatial mapping of band bending in semiconductor devices using in-situ quantum sensors

Band bending is a central concept in solid-state physics that arises from local variations in charge distribution especially near semiconductor interfaces and surfaces. Its precision measurement is vital in a variety of contexts from the optimisation of field effect transistors to the engineering of qubit devices with enhanced stability and coherence. Existing methods are surface sensitive and are unable to probe band bending at depth from surface or bulk charges related to crystal defects. Here we propose an in-situ method for probing band bending in a semiconductor device by imaging an array of atomic-sized quantum sensing defects to report on the local electric field. We implement the concept using the nitrogen-vacancy centre in diamond, and map the electric field at different depths under various surface terminations. We then fabricate a two-terminal device based on the conductive two-dimensional hole gas formed at a hydrogen-terminated diamond surface, and observe an unexpected spatial modulation of the electric field attributed to a complex interplay between charge injection and photo-ionisation effects. Our method opens the way to three-dimensional mapping of band bending in diamond and other semiconductors hosting suitable quantum sensors, combined with simultaneous imaging of charge transport in complex operating devices.Comment: This is a pre-print of an article published in Nature Electronics. The final authenticated version is available online at https://dx.doi.org/10.1038/s41928-018-0130-

The Maritime Labour Convention, 2006 – Reflections on Challenges for Flag State Implementation

This paper begins by providing a brief overview of the International Labour Organization’s Maritime Labour Convention, 2006 (MLC, 2006), noting that this Convention, often called the “Seafarers’ bill of rights”, seeks to achieve both social and labour rights (“decent work”) for seafarers and fair competition (achieving a level-playing field) for shipowners. It has been described as the “fourth pillar” of the international maritime regulatory regime complementing the major International Maritime Organization conventions. The paper provides a brief update on international efforts to achieve the 30/33 formula needed to bring the Convention into force [at present, the tonnage element, 33% has been achieved already with coverage now at 54% of the world fleet (by gross tonnage), with 18 ratifications]. It then explores challenges faced by flag States in connection with capacity to implement the ship inspection and certification system under the MLC, 2006 and other difficulties with respect to legal implementation by the flag States. The paper also comments on some challenges in connection with port State, coastal State and labour-supplying State responsibilities. The paper points out that the MLC, 2006 is a comprehensive code that covers diverse issues and a wider range of both ships and seafarers than previous conventions. It often requires interdepartmental cooperation to implement its requirements at the national level. The paper concludes that, despite the slower pace of ratification in some regions, largely because of the recent economic and other crises, it appears that many actors in the maritime sector are already actively engaged in MLC, 2006 implementation, often ahead of governments. The question is not “if” but “when” the formula will be achieved to allow the MLC, 2006 to enter into force

New Higgs Production Mechanism in Composite Higgs Models

Composite Higgs models are only now starting to be probed at the Large Hadron Collider by Higgs searches. We point out that new resonances, abundant in these models, can mediate new production mechanisms for the composite Higgs. The new channels involve the exchange of a massive color octet and single production of new fermion resonances with subsequent decays into the Higgs and a Standard Model quark. The sizable cross section and very distinctive kinematics allow for a very clean extraction of the signal over the background with high statistical significance. Heavy gluon masses up to 2.8 TeV can be probed with data collected during 2012 and up to 5 TeV after the energy upgrade to $\sqrt{s}=14$ TeV.Comment: 27 pages, 22 figures. V2: typos corrected, matches published versio

Manifestations of Top Compositeness at Colliders

We explore the possibility that the right-handed top quark is composite, identifying possible signatures of compositeness and how they might manifest themselves at the LHC and Tevatron. We perform a complete analysis of the dimension six modifications of the top coupling to gluons and find that cancellations among operators in the t\bar{t} rate allow for very low compositeness scales, but this can be drastically improved by looking at kinematic distributions. Turning to the LHC, we examine four top production from a dimension six four-top operator and estimate the LHC with 100 {\rm fb}^{-1} collected luminosity to be sensitive to compositeness scales as high as 5 TeV.Comment: 8 pages, 6 figures, updated figure 6, updated references, final version published in JHE

Search for anomalous top-gluon couplings at LHC revisited

Through top-quark pair productions at LHC, we study possible effects of nonstandard top-gluon couplings yielded by SU(3)xSU(2)xU(1) invariant dimension-6 effective operators. We calculate the total cross section and also some distributions for p p -> t tbar X as functions of two anomalous-coupling parameters, i.e., the chromoelectric and chromomagnetic moments of the top, which are constrained by the total cross section sigma(p pbar -> t tbar X) measured at Tevatron. We find that LHC might give us some chances to observe sizable effects induced by those new couplings.Comment: One comment and related two refs. added. Final version (to appear in Eur.Phys.J. C

Theories for the Fermi Scale

I give a short review of our present understanding of new theories of the electroweak scale, with emphasis on recent progress. Plenary talk at the EPS 2007 Conference at Manchester.Comment: 14 pages, EPS 2007 Conferenc

The effects of non-universal extra dimensions on the radiative lepton flavor decays \mu\to e\gamma and \tau\to \mu\gamma in the two Higgs doublet model

We study the effect of non-universal extra dimensions on the branching ratios of the lepton flavor violating processes \mu\to e\gamma and \tau\to \mu\gamma in the general two Higgs doublet model. We observe that these effects are small for a single extra dimension, however, in the case of two extra dimensions there is a considerable enhancement in the additional contributions.Comment: 16 Pages, 9 Figure