Land Grant Application- Libby, James (Poland)

Land grant application submitted to the Maine Land Office on behalf of James Libby for service in the Revolutionary War, by their widow Sally.https://digitalmaine.com/revolutionary_war_me_land_office/1569/thumbnail.jp

Characterization of a RNA that accumulates only in non-dividing Tetrahymena thermophila

Tetrahymena thermophila is a fresh water, ciliated protozoan that is able to regulate the expression of various sets of genes in response to physiological changes. When cells are transferred from their normal growth medium to starvation medium, cell division is arrested. When cells are transferred back to growth medium, cells are able to resume dividing. If cells are heat shocked at 41°C or above, cells are not able to divide at these temperatures, but if returned to 30°C, will resume dividing. The environmental condition in which the cells are placed can dramatically effect cell division;In this study, we have characterized the accumulation of a 1460 nucleotide long, poly A+ RNA that is induced to become an abundant RNA in non-dividing cells. This RNA, called C5, is not present in growing cells, but accumulates during starvation, heat shock, and during stationary growth. These conditions will cause cell division to be arrested. When cells are allowed to resume dividing, the concentration of C5 RNA drops rapidly as cells begin dividing. For this RNA to be accumulated and maintained, ongoing protein synthesis is required, but not continued DNA replication. Although this RNA has some properties of a poly A+ mRNA, our evidence suggests that C5 RNA does not encode a peptide. The function of this RNA in division arrested cells is not known

Coronavirus Closures Could Lead to a Radical Revolution in Conservation

In the early days of the COVID-19 lockdowns, social media was flooded with reports of animals reclaiming abandoned environments. According to one widely shared post, dolphins had returned to the canals of Venice. While many of those stories have since been debunked, conservationists are providing legitimate reports of cleaner air and water, and wildlife reclaiming contested habitats. With widespread closures of parks and conservation areas around the world, could this be an opportunity to transform the way we manage and use these protected environments

Feeding Interactions Between Juvenile and Adult Flightless Cormorants.

We report observations on chick feedings by adult Flightless Cormorants Phalacrocorax harrisi, indicating that, contrary to the literature, the sequence of interaction is similar to that of other Pelecaniformes

First simulation study of trackless events in the INO-ICAL detector to probe the sensitivity to atmospheric neutrinos oscillation parameters

The proposed India-based Neutrino Observatory will host a 50 kton magnetized iron calorimeter (ICAL) with resistive plate chambers as its active detector element. Its primary focus is to study charged-current interactions of atmospheric muon neutrinos via the reconstruction of muons in the detector. We present the first study of the energy and direction reconstruction of the final state lepton and hadrons produced in charged current interactions of atmospheric electron neutrinos at ICAL and the sensitivity of these events to neutrino oscillation parameters $\theta_{23}$ and $\Delta m_{32}^2$. However, the signatures of these events are similar to those from neutral-current interactions and charged-current muon neutrino events in which the muon track is not reconstructed. On including the entire set of events that do not produce a muon track, we find that reasonably good sensitivity to $\theta_{23}$ is obtained, with a relative $1\sigma$ precision of 15% on the mixing parameter $\sin^2\theta_{23}$, which decreases to 21%, when systematic uncertainties are considered

When do analysts adjust for biases in management guidance? Effects of guidance track record and analysts' incentives

Prior research indicates that analysts do not fully adjust for the general downward bias in earnings guidance issued by management. We report the results of two experiments designed to investigate how guidance track record and analysts incentives jointly explain the extent to which analysts adjust for guidance bias. Our results suggest that analysts with accuracy incentives adjust for managements track record of downwardly biased guidance when the bias is relatively small (one cent), but those with relationship incentives do not. Furthermore, the difference in adjustment is larger when the bias track record is inconsistent than when it is consistent. Also, when guidance bias is larger (two cents) relative to smaller (one cent), analysts with relationship incentives partially adjust, as they appear to strike a balance between accuracy and their desire to please management. These findings hold implications for investors, regulators, and the interpretation of prior research