Multifractality of wavefunctions at the quantum Hall transition revisited

We investigate numerically the statistics of wavefunction amplitudes $\psi({\bf r})$ at the integer quantum Hall transition. It is demonstrated that in the limit of a large system size the distribution function of $|\psi|^2$ is log-normal, so that the multifractal spectrum $f(\alpha)$ is exactly parabolic. Our findings lend strong support to a recent conjecture for a critical theory of the quantum Hall transition.Comment: 4 pages Late

Optical activity of neutrinos and antineutrinos

Using the one-loop helicity amplitudes for low-energy $\nu\gamma\to\nu\gamma$ and $\bar\nu\gamma\to\bar\nu\gamma$ scattering in the standard model with massless neutrinos, we study the optical activity of a sea of neutrinos and antineutrinos. In particular, we estimate the values of the index of refraction and rotary power of this medium in the absence of dispersion.Comment: Additional reference

Subversion of actin dynamics by EspM effectors of attaching and effacing bacterial pathogens

Rho GTPases are common targets of bacterial toxins and type III secretion system effectors. IpgB1 and IpgB2 of Shigella and Map of enteropathogenic (EPEC) and enterohemorrhagic (EHEC) Escherichia coli were recently grouped together on the basis that they share a conserved WxxxE motif. In this study, we characterized six WxxxE effectors from attaching and effacing pathogens: TrcA and EspM1 of EPEC strain B171, EspM1 and EspM2 of EHEC strain Sakai and EspM2 and EspM3 of Citrobacter rodentium. We show that EspM2 triggers formation of global parallel stress fibres, TrcA and EspM1 induce formation of localized parallel stress fibres and EspM3 triggers formation of localized radial stress fibres. Using EspM2 and EspM3 as model effectors, we report that while substituting the conserved Trp with Ala abolished activity, conservative Trp to Tyr or Glu to Asp substitutions did not affect stress-fibre formation. We show, using dominant negative constructs and chemical inhibitors, that the activity of EspM2 and EspM3 is RhoA and ROCK-dependent. Using Rhotekin pull-downs, we have shown that EspM2 and EspM3 activate RhoA; translocation of EspM2 and EspM3 triggered phosphorylation of cofilin. These results suggest that the EspM effectors modulate actin dynamics by activating the RhoA signalling pathway

Strong Phase Separation in a Model of Sedimenting Lattices

We study the steady state resulting from instabilities in crystals driven through a dissipative medium, for instance, a colloidal crystal which is steadily sedimenting through a viscous fluid. The problem involves two coupled fields, the density and the tilt; the latter describes the orientation of the mass tensor with respect to the driving field. We map the problem to a 1-d lattice model with two coupled species of spins evolving through conserved dynamics. In the steady state of this model each of the two species shows macroscopic phase separation. This phase separation is robust and survives at all temperatures or noise levels--- hence the term Strong Phase Separation. This sort of phase separation can be understood in terms of barriers to remixing which grow with system size and result in a logarithmically slow approach to the steady state. In a particular symmetric limit, it is shown that the condition of detailed balance holds with a Hamiltonian which has infinite-ranged interactions, even though the initial model has only local dynamics. The long-ranged character of the interactions is responsible for phase separation, and for the fact that it persists at all temperatures. Possible experimental tests of the phenomenon are discussed.Comment: To appear in Phys Rev E (1 January 2000), 16 pages, RevTex, uses epsf, three ps figure

Photons, neutrinos and optical activity

We compute the one-loop helicity amplitudes for low-energy $\nu\gamma\to\nu\gamma$ scattering and its crossed channels in the standard model with massless neutrinos. In the center of mass, with $\sqrt{s} = 2\omega\ll 2m_e$, the cross sections for these $2\to 2$ channels grow roughly as $\omega^6$. The scattered photons in the elastic channel are circularly polarized and the net value of the polarization is non-zero. We also present a discussion of the optical activity of a sea of neutrinos and estimate the values of its index of refraction and rotary power.Comment: 9 pages, ReVTeX4, 6 figures include

Association Between Lifetime Marijuana Use and Cognitive Function in Middle Age: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

Marijuana use is increasingly common in the United States. It is unclear whether it has long-term effects on memory and other domains of cognitive function. To study the association between cumulative lifetime exposure to marijuana use and cognitive performance in middle age. We used data from the Coronary Artery Risk Development in Young Adults (CARDIA) study, a cohort of 5115 black and white men and women aged 18 to 30 years at baseline from March 25, 1985, to June 7, 1986 (year 0), and followed up over 25 years from June 7, 1986, to August 31, 2011, to estimate cumulative years of exposure to marijuana (1 year = 365 days of marijuana use) using repeated measures and to assess associations with cognitive function at year 25. Linear regression was used to adjust for demographic factors, cardiovascular risk factors, tobacco smoking, use of alcohol and illicit drugs, physical activity, depression, and results of the mirror star tracing test (a measure of cognitive function) at year 2. Data analysis was conducted from June 7, 1986, to August 31, 2011. Three domains of cognitive function were assessed at year 25 using the Rey Auditory Verbal Learning Test (verbal memory), the Digit Symbol Substitution Test (processing speed), and the Stroop Interference Test (executive function). Among 3385 participants with cognitive function measurements at the year 25 visit, 2852 (84.3%) reported past marijuana use, but only 392 (11.6%) continued to use marijuana into middle age. Current use of marijuana was associated with worse verbal memory and processing speed; cumulative lifetime exposure was associated with worse performance in all 3 domains of cognitive function. After excluding current users and adjusting for potential confounders, cumulative lifetime exposure to marijuana remained significantly associated with worse verbal memory. For each 5 years of past exposure, verbal memory was 0.13 standardized units lower (95% CI, -0.24 to -0.02; P = .02), corresponding to a mean of 1 of 2 participants remembering 1 word fewer from a list of 15 words for every 5 years of use. After adjustment, we found no associations with lower executive function (-0.03 [95% CI, -0.12 to 0.07]; P = .56) or processing speed (-0.04 [95% CI, -0.16 to 0.08]; P = .51). Past exposure to marijuana is associated with worse verbal memory but does not appear to affect other domains of cognitive function

Axial vector current in an electromagnetic field and low-energy neutrino-photon interactions

An expression for the axial vector current in a strong, slowly varying electromagnetic field is obtained. We apply this expression to the construction of the effective action for low-energy neutrino-photon interactions.Comment: 6 pages, references updated, final version to appear in Phys. Rev.

Weak localization of disordered quasiparticles in the mixed superconducting state

Starting from a random matrix model, we construct the low-energy effective field theory for the noninteracting gas of quasiparticles of a disordered superconductor in the mixed state. The theory is a nonlinear sigma model, with the order parameter field being a supermatrix whose form is determined solely on symmetry grounds. The weak localization correction to the field-axis thermal conductivity is computed for a dilute array of s-wave vortices near the lower critical field H_c1. We propose that weak localization effects, cut off at low temperatures by the Zeeman splitting, are responsible for the field dependence of the thermal conductivity seen in recent high-T_c experiments by Aubin et al.Comment: RevTex, 8 pages, 1 eps figure, typos correcte

Atenolol versus losartan in children and young adults with Marfan's syndrome

BACKGROUND : Aortic-root dissection is the leading cause of death in Marfan's syndrome. Studies suggest that with regard to slowing aortic-root enlargement, losartan may be more effective than beta-blockers, the current standard therapy in most centers. METHODS : We conducted a randomized trial comparing losartan with atenolol in children and young adults with Marfan's syndrome. The primary outcome was the rate of aortic-root enlargement, expressed as the change in the maximum aortic-root-diameter z score indexed to body-surface area (hereafter, aortic-root z score) over a 3-year period. Secondary outcomes included the rate of change in the absolute diameter of the aortic root; the rate of change in aortic regurgitation; the time to aortic dissection, aortic-root surgery, or death; somatic growth; and the incidence of adverse events. RESULTS : From January 2007 through February 2011, a total of 21 clinical centers enrolled 608 participants, 6 months to 25 years of age (mean [+/- SD] age, 11.5 +/- 6.5 years in the atenolol group and 11.0 +/- 6.2 years in the losartan group), who had an aorticroot z score greater than 3.0. The baseline-adjusted rate of change (+/- SE) in the aortic-root z score did not differ significantly between the atenolol group and the losartan group (-0.139 +/- 0.013 and -0.107 +/- 0.013 standard-deviation units per year, respectively; P = 0.08). Both slopes were significantly less than zero, indicating a decrease in the degree of aortic-root dilatation relative to body-surface area with either treatment. The 3-year rates of aortic-root surgery, aortic dissection, death, and a composite of these events did not differ significantly between the two treatment groups. CONCLUSIONS : Among children and young adults with Marfan's syndrome who were randomly assigned to losartan or atenolol, we found no significant difference in the rate of aorticroot dilatation between the two treatment groups over a 3-year period

Materials recycle and waste management in fusion power reactors. Progress report for 1982

Several components of a STARFIRE fusion reactor have been studied. The breeding ratios were calculated as a function of lithium enrichment and neutron multiplier for systems containing either Li/sub 2/O or LiAlO/sub 2/. The lithium requirements for a fusion economy were also estimated for those cases and the current US resources were found to be adequate. However, competition with other lithium demands in the future emphasizes the need for recovering and reusing lithium. The radioactivities induced in the breeder and the impurities responsible for their formation were determined. The residual radioactivities of several low-activation structural materials were compared with the radioactivity from the prime candidate alloy (PCA) a titanium modified Type 316 stainless steel used in STARFIRE. The impurities responsible for the radioactivity levels were identified. From these radioactive impurity levels it was determined that V15Cr5Ti could meet the requirements for shallow land burial as specified by the Nuclear Regulatory Commission (10CFR61), whereas PCA would require a more restrictive disposal mode, i.e. in a geologic medium. The costs for each of these disposal modes were then estimated