243 research outputs found
Effect of high oxygen pressure annealing on superconducting Nd1.85Ce0.15CuO4 thin films by pulsed laser deposition from Cu-enriched targets
We show that the quality of Nd1.85Ce0.15CuO4 films grown by pulsed laser
deposition can be enhanced by using a non-stoichiometric target with extra
copper added to suppress the formation of a parasitic (Nd, Ce)2O3 phase. The
properties of these films are less dependent on the exact annealing procedure
after deposition as compared to films grown from a stoichiometric target. Film
growth can be followed by a 1 bar oxygen annealing, after an initial vacuum
annealing, while retaining the superconducting properties and quality. This
enables the integration of electron-doped cuprates with their hole-doped
counterparts on a single chip, to create, for example, superconducting
pn-junctions.Comment: This is an author-created, un-copyedited version of an article
accepted for publication in Superconductor Science and Technology. The
publisher is not responsible for any errors or omissions in this version of
the manuscript or any version derived from it. The Version of Record is
available online at http://dx.doi.org/10.1088/0953-2048/27/4/04401
Carrier freeze-out induced metal-insulator transition in oxygen deficient SrTiO3 films
We report the optical, electrical transport, and magnetotransport properties
of high quality oxygen deficient SrTiO3 (STO) single crystal film fabricated by
pulsed laser deposition and reduced in the vacuum chamber. The oxygen vacancy
distribution in the thin film is expected to be uniform. By comparing the
electrical properties with oxygen deficient bulk STO, it was found that the
oxygen vacancies in bulk STO is far from uniform over the whole material. The
metal-insulator transition (MIT) observed in the oxygen deficient STO film was
found to be induced by the carrier freeze-out effect. The low temperature
frozen state can be re-excited by an electric field, Joule heating, and
surprisingly also a large magnetic field.Comment: 5 pages, 5 figure
The effect of bone marrow aspiration strategy on the yield and quality of human mesenchymal stem cells
Introduction Large inter-donor differences exist in human mesenchymal stem cell (hMSC) yield and the response of these cells to osteogenic stimuli. The source of these differences may be clinical differences in stem cell characteristics between individuals or the aspiration procedure itself
A membership categorization analysis of roles, activities and relationships in inclusive research conducted by co-researchers with intellectual disabilities
Contains fulltext :
204050.pdf (publisher's version ) (Open Access
Mental healthcare for adults with mild intellectual disabilities: population-based database study in Dutch mental health services
BackgroundAdults with mild intellectual disability (MID) experience more mental health disorders than the general population. However, mental healthcare may be insufficiently tailored to match their needs. Detailed information is lacking regarding care provided to people with MID in mental health services. AimsTo compare mental health disorders and care provided to patients with and without MID in Dutch mental health services, including patients with missing MID status in the service files. MethodIn this population-based database study, we used a Statistics Netherlands mental health service database, containing health insurance claims of patients who utilised advanced mental health services in 2015-2017. Patients with MID were identified by linking this database with Statistic Netherlands' social services and long-term care databases. ResultsWe identified 7596 patients with MID, of whom 60.6% had no intellectual disability registration in the service files. Compared with patients without intellectual disability (n = 329 864), they had different profiles of mental health disorders. They received fewer diagnostic (odds ratio 0.71, 95% CI 0.67-0.75) and treatment activities (odds ratio 0.56, 95% CI 0.53-0.59), and required more interprofessional consultations outside of the service (odds ratio 2.06, 95% CI 1.97-2.16), crisis interventions (odds ratio 2.00, 95% CI 1.90-2.10) and mental health-related hospital admissions (odds ratio 1.72, 95% CI 1.63-1.82). ConclusionsPatients with MID in mental health services have different profiles of mental health disorders and care than patients without intellectual disability. In particular, fewer diagnostics and treatments are provided, especially in those with MID with no intellectual disability registration, putting patients with MID at risk of undertreatment and poorer mental health outcomes.Stress-related psychiatric disorders across the life spa
High throughput surface plasmon resonance imaging method for clinical detection of presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection
Surface Plasmon Resonance imaging (SPRi) was used to determine the presence and strength of binding of IgG, IgM and IgA against the Receptor Binding Domain (RBD) of SARS-CoV-2 in sera of 102 CoViD-19 and non-CoViD-19 patients. The SPRi assay simultaneously measures the antibody isotype levels and the strength of binding to the RBD of ultimate 384 patient samples in one run. It turns out that during the course of the disease, the IgG levels and strength of binding increased while generally the IgM and IgA levels go down. Recovered patients all show high strength of binding of the IgG type to the RBD protein. The anti-RBD immunoglobulins SPRi assay provides additional insights in the immune status of patients recovering from CoViD-19. This new high throughput method can be applied for the assessment of the quality of the immune reaction of healthy individuals to SARS-CoV-2 and its mutants in vaccination programs.•Surface Plasmon Resonance imaging is an unprecedented technology for high throughput screening of antibody profiling of CoViD19 patients.•Fingerprinting of isotypes IgM, IgG and IgA can be performed for 384 patients in one run.•An affinity maturation effect was shown for patients recovering from CoViD19
Nonlinear Insulator in Complex Oxides
The insulating state is one of the most basic electronic phases in condensed
matter. This state is characterised by an energy gap for electronic excitations
that makes an insulator electrically inert at low energy. However, for complex
oxides, the very concept of an insulator must be re-examined. Complex oxides
behave differently from conventional insulators such as SiO2, on which the
entire semiconductor industry is based, because of the presence of multiple
defect levels within their band gap. As the semiconductor industry is moving to
such oxides for high-dielectric (high-k) materials, we need to truly understand
the insulating properties of these oxides under various electric field
excitations. Here we report a new class of material called nonlinear insulators
that exhibits a reversible electric-field-induced metal-insulator transition.
We demonstrate this behaviour for an insulating LaAlO3 thin film in a
metal/LaAlO3/Nb-SrTiO3 heterostructure. Reproducible transitions were observed
between a low-resistance metallic state and a high-resistance non-metallic
state when applying suitable voltages. Our experimental results exclude the
possibility that diffusion of the metal electrodes or oxygen vacancies into the
LaAlO3 layer is occurring. Instead, the phenomenon is attributed to the
formation of a quasi-conduction band (QCB) in the defect states of LaAlO3 that
forms a continuum state with the conduction band of the Nb-SrTiO3. Once this
continuum (metallic) state is formed, the state remains stable even when the
voltage bias is turned off. An opposing voltage is required to deplete the
charges from the defect states. Our ability to manipulate and control these
defect states and, thus, the nonlinear insulating properties of complex oxides
will open up a new path to develop novel devices.Comment: 23 pages, 4 figure
Improving Environmental Capacities for Health Promotion in Support Settings for People with Intellectual Disabilities: Inclusive Design of the DIHASID Tool
People with intellectual disabilities (ID) have unhealthier lifestyles than the general population. To sustainably improve their lifestyle and health status, a whole-system approach to creating healthy environments is crucial. To gain insight into how support for physical activity and healthy nutrition can be embedded in a setting, asset mapping can be helpful. Asset mapping involves creating a bottom–up overview of promoting and protective factors for health. However, there is no asset mapping tool available for ID support settings. This study aims to develop an asset mapping tool in collaboration with people with ID to gain insight into assets for healthy nutrition and physical activity in such settings. The tool is based on previous research and development continued in an iterative and inclusive process in order to create a clear, comprehensive, and usable tool. Expert interviews (n = 7), interviews with end-users (n = 7), and pilot testing (n = 16) were conducted to refine the tool. Pilot participants perceived the tool as helpful in pinpointing perceived assets and in prompting ideas on how to create inclusive environments with support for physical activity and healthy nutrition. This overview of assets can be helpful for mobilizing assets and building the health-promoting capacities of ID support settings
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