Paciente pediátrico portador de transtorno espectro autista em um ambulatório: relato de experiência / Pediatric patient with autistic spectrum disorder in an outpatient clinic: experience report

O transtorno do espectro autista (TEA) é um grupo de distúrbios do desenvolvimento neurológico de início precoce, caracterizado por comprometimento das habilidades sociais e de comunicação, além de comportamentos estereotipados. Este trabalho teve como objetivo relatar a experiência vivenciadas durante o período das aulas práticas em um ambulatório pediátrico, pontuando a assistência de enfermagem para um paciente pediátrico com Transtorno do Espectro Autista (TEA), e os cuidados voltados para as suas enfermidades. Trata-se de um estudo descritivo do tipo relato de experiência, realizado por acadêmicas de enfermagem da Universidade da Amazônia - UNAMA, durante as aulas práticas em um ambulatório infantil em Belém – PA, concluímos que a importância do enfermeiro sobre orientar os pais, e direciona-los a consultar o filho com outros profissionais da equipe multiprofissional de saúde, e para melhorar a qualidade de vida da criança.

Perfil clínico-epidemiológico de vítimas de traumatismo crânio encefálico em Rondônia: estudo coorte retrospectivo entre 2018 e 2021 / Clinical-epidemiological profile of traumatic brain injury victims in Rondônia: retrospective cohort study from 2018 to 2021

O traumatismo crânio encefálico (TCE) é uma lesão que ocorre a partir de um trauma externo, podendo causar alterações anatômicas no crânio da vítima. Entre as causas mais comuns, pode-se citar acidentes automobilísticos, atropelamentos, acidentes com motos e bicicletas, agressões físicas, quedas, lesões por armas de fogo. Este estudo objetiva-se identificar o perfil sociodemográfico de vítimas de TCE no estado de Rondônia entre os anos de 2018 a 2021. Trata-se de um estudo retrospectivo, descritivo e observacional, com abordagem qualiquantitativa. A coleta dos dados secundários ocorreu através do Departamento de Informática do Sistema Único de Saúde – DATASUS, disponibilizado no TABNET. Fizeram parte deste estudo, 798 vítimas de acidentes ou causas externas notificados no estado de Rondônia. Os resultados encontrados neste estudo evidenciaram as causas externas relacionadas aos óbitos, sendo as mais comuns: exposição a acidentes e outros fatores/causas não específicas, quedas, motociclistas traumatizados e agressões, correspondendo a um total de 79,82% das causas associadas aos óbitos. Os resultados deste estudo possibilitaram caracterizar o perfil clínico-epidemiológico das mortes notificadas no estado de Rondônia em decorrência às causas ou fatores externos que levaram indivíduos a evoluírem para TCE

Deltamethrin pyrethroid susceptibility characterization of Triatoma sordida Stål, 1859 (Hemiptera: Reduviidae) populations in the Northern Region of Minas Gerais, Brazil

Submitted by Nuzia Santos ([email protected]) on 2015-03-26T16:49:39Z No. of bitstreams: 1 2014_174.pdf: 736569 bytes, checksum: a487d3f862f8997b06a5dc09cb460c64 (MD5)Approved for entry into archive by Nuzia Santos ([email protected]) on 2015-03-26T16:49:46Z (GMT) No. of bitstreams: 1 2014_174.pdf: 736569 bytes, checksum: a487d3f862f8997b06a5dc09cb460c64 (MD5)Approved for entry into archive by Nuzia Santos ([email protected]) on 2015-03-26T16:51:47Z (GMT) No. of bitstreams: 1 2014_174.pdf: 736569 bytes, checksum: a487d3f862f8997b06a5dc09cb460c64 (MD5)Made available in DSpace on 2015-03-26T16:51:47Z (GMT). No. of bitstreams: 1 2014_174.pdf: 736569 bytes, checksum: a487d3f862f8997b06a5dc09cb460c64 (MD5) Previous issue date: 2014Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, MG, BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, MG, BrasilIntroduction: Triatoma sordida is the most captured Triatomine species in the Brazilian artifi cial environment. In 2008, the discovery of three Triatomine populations with altered susceptibilities to deltamethrin highlighted the importance of investigating the genetic potential for resistance in triatomines. The purpose of this study was to characterize the susceptibility to deltamethrin of peridomestic T. sordida populations in Minas Gerais, Brazil. Methods: A susceptibility reference lineage derived from Uberaba, Minas Gerais, Brazil was used. Serial dilutions of deltamethrin were prepared and applied to the dorsal abdomen of first instar nymphs. The control group received only pure acetone. Mortality was evaluated after 72h. Qualitative tests assessed mortality in response to a diagnostic dose of 1xLD99 of the susceptibility reference lineage. Results: Susceptibility profi le characterization of T. sordida populations revealed resistance ratios (RR50s) ranging from 0.42 to 3.94. The percentage mortality in response to the diagnostic dose varied from 70% to 100%. A comparison of the results obtained in the quantitative and qualitative assays demonstrated a lack of correspondence for some populations. Conclusions: We demonstrated that only T. sordida populations that present a RR50>1.0 have altered susceptibility, and the execution of simultaneous fi eld and laboratory tests is required to understand the actual effect of vector control. A possible cause of the observed resistance ratios might be the continuous use of pyrethroids in Brazil since the 1980s

Susceptibility of Triatoma brasiliensis from state of Ceará, Northeastern Brazil, to the pyrethroid deltamethrin

After controlling Triatoma infestans in Brazil, other species of triatomine that were considered minor in the transmission of Chagas disease became important. The persistence of Triatoma brasiliensis in Northeastern Brazil, associated with reinfection of domestic environments recently sprayed with pyrethroids, may be a signal of susceptibility alteration of this species to this insecticide. Specimens of T. brasiliensis from the municipality of Tauá, state of Ceará, were captured before and one year after spraying. They were submitted to bioassays using deltamethrin. The LD50 ranged from 0.19-0.33 ng of deltamethrin/nymph. The resistance ratio among samples from Tauá varied from 1.16-1.79 in the samples captured before the spraying and 1.00-1.74 in the samples captured one year after spraying, demonstrating that the two populations were equally susceptible to deltamethrin. The small difference in susceptibility between the two captures suggests that T. brasiliensis obtained in the second capture are from new invasions of the domestic environment and that the insecticide did not select resistant individuals. Therefore, it is suggested that T. brasiliensis control be carried out supplementing the regular use of pyrethroids with complementary measures, such as improvement of the dwellings and health education

Pré-triagem não laboratorial para diabetes mellitus tipo 2 em escolares de 3 a 6 anos na Amazônia Oriental, Brasil

Type 2 Diabetes mellitus is a chronic disease that affects more than 415 million people worldwide. Some risk factors to consider among children are poor diet, obesity, physical inactivity, family history, if the mother has been diagnosed with gestational diabetes mellitus and early weaning. Our objective was to propose a non-lab pre-screening test for Type 2 Diabetes mellitus among preschoolers aged 3 to 6 years old in the Amazon region, Maraba, Brazil. Our sample comprised (N=425) children enrolled in a public preschool and their respective caregivers/parents. A discriminant analysis was used to test the score's ability to maximize the differences between groups according to the relation to the risk factors for Type 2 Diabetes mellitus. Our results suggested that our proposed pre-screening test for Type 2 Diabetes mellitus-using assessment of risk factors is as simple as statistically significant based on heredity, overweight/obesity, physical inactivity, and habit of intake high-calorie foods. The proposed pre-screening test for Type 2 Diabetes mellitus using assessment of risk factors is a simple as statistically significant method for potentially identifying children at risk for Type 2 Diabetes mellitus in schools.La Diabetes mellitus tipo 2 es una enfermedad crónica que afecta a más de 415 millones de personas en todo el mundo. Algunos factores de riesgo a considerar en los niños son la mala alimentación, la obesidad, la inactividad física, los antecedentes familiares, si la madre ha sido diagnosticada con diabetes mellitus gestacional y el destete precoz. Nuestro objetivo fue proponer una prueba de preselección no de laboratorio para Diabetes mellitus tipo 2 entre preescolares de 3 a 6 años de edad en la región amazónica, Maraba, Brasil. Nuestra muestra estuvo compuesta por (N=425) niños matriculados en un preescolar público y sus respectivos cuidadores/padres. Se utilizó una análisis discriminante para probar la capacidad de la puntuación para maximizar las diferencias entre los grupos según la relación con los factores de riesgo para la diabetes mellitus tipo 2. Nuestros resultados sugirieron que nuestra prueba de preselección propuesta para la diabetes mellitus tipo 2, que utiliza la evaluación de los factores de riesgo, es tan simple como estadísticamente significativa en función de la herencia, el sobrepeso/obesidad, la inactividad física y el hábito de ingerir alimentos ricos en calorías. La prueba de preselección propuesta para la diabetes mellitus tipo 2 mediante la evaluación de los factores de riesgo es un método simple y estadísticamente significativo para identificar potencialmente a los niños en riesgo de diabetes mellitus tipo 2 en las escuelas.Diabetes mellitus tipo 2 é uma doença crônica que afeta mais de 415 milhões de pessoas em todo o mundo. Alguns fatores de risco, relevantes entre as crianças, são: má alimentação, obesidade, sedentarismo, história familiar, diabetes mellitus gestacional e desmame precoce. O objetivo deste estudo foi propor um teste não laboratorial de pré-triagem para diabetes mellitus tipo 2 entre pré-escolares de 3 a 6 anos na região Amazônica, Marabá, Brasil. Nossa amostra foi composta (N=425) crianças matriculadas em uma pré-escola pública e seus respectivos responsáveis/pais. A análise discriminante foi utilizada para testar a capacidade do escore em maximizar as diferenças entre os grupos de acordo com a relação dos fatores de risco para Diabetes Mellitus tipo 2. Nossos resultados sugeriram que nosso teste de pré-triagem proposto para Diabetes Mellitus tipo 2 usando a avaliação de fatores de risco são simples, entretanto, são estatisticamente significativos com base na hereditariedade, sobrepeso / obesidade, sedentarismo e hábito de ingestão de alimentos altamente calóricos. O teste de pré-triagem proposto para Diabetes Mellitus tipo 2 usando avaliação de fatores de risco é um método simples e estatisticamente significativo para identificar potencialmente crianças em risco de desenvolver Diabetes Mellitus tipo 2 nas escolas

First Record of Zaprionus tuberculatus Malloch, 1932 (Diptera: Drosophilidae) in Minas Gerais, Brazil

ABSTRACT The Afrotropical Zaprionus Coquillett, 1902 (Diptera: Drosophilidae) has gained visibility since the 1990s due to the geographic expansion of Zaprionus indianus Gupta, 1970. More recently, a second species, Zaprionus tuberculatus Malloch, 1932, invaded regions outside its original African regions, causing economic concerns, particularly in Europe. In 2021, Z. tuberculatus was captured for the first time in the Americas, specifically in urban parks, and preserved fragments of the Brazilian Cerrado, causing concerns about the competition with native drosophilids. Here we report the occurrence of Z. tuberculatus 900 km from its first record in urban and rural areas of Viçosa, MG, but not in forest fragments. Considering the great capacity for dispersion and the potential of Z. tuberculatus to compete with native drosophilids species, as well as the potential harm to fruit production when co-occurring with Drosophila suzukii (Matsumura, 1931), further studies would be necessary to monitor this invasion and create mechanisms to control it

Markers for the population genetics studies of Triatoma sordida (Hemiptera: Reduviidae).

Submitted by Nuzia Santos ([email protected]) on 2016-02-04T13:08:07Z No. of bitstreams: 1 Markers for the population genetics studies.pdf: 3604761 bytes, checksum: 7f8913d71b7e2c1494ed8ed71ad3ce1d (MD5)Approved for entry into archive by Nuzia Santos ([email protected]) on 2016-02-04T13:11:54Z (GMT) No. of bitstreams: 1 Markers for the population genetics studies.pdf: 3604761 bytes, checksum: 7f8913d71b7e2c1494ed8ed71ad3ce1d (MD5)Made available in DSpace on 2016-02-04T13:11:54Z (GMT). No. of bitstreams: 1 Markers for the population genetics studies.pdf: 3604761 bytes, checksum: 7f8913d71b7e2c1494ed8ed71ad3ce1d (MD5) Previous issue date: 2015Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, Minas Gerais BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, Minas Gerais BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, Minas Gerais BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, Minas Gerais BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, Minas Gerais BrasilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, Minas Gerais BrasilBackground: Triatoma sordida, a vector of Trypanosoma cruzi, is native of Brazil, Bolivia, Paraguay, Argentina, and Uruguay, and occurs primarily in peridomiciles. Currently, it is the species most frequently captured by the Chagas Disease Control Program in Brazil. For this reason, population genetic studies attract great interest, as they can provide further information about the dispersal and household invasion processes of this species. In the absence of suitable markers, the objective of this study was to test the cross amplification of microsatellite primers. Findings: 23 primers were tested for microsatellite loci already described for other species of the genus Triatoma sp. Forty four specimens of T. sordida captured in the north of Minas Gerais were used to validate the use of standardized loci for population genetic analyses. It was possible to amplify 10 of the 23 loci tested for T. sordida. Conclusions: This is the first study that provides 10 microsatellite markers for population analysis of this triatomine species. Cross-amplification of primers can be used among other phylogenetically related species whose loci are already available for stud

Toxicological profile of deltamethrin in Triatoma brasiliensis (Hemiptera: Reduviidae) in State of Ceará; Northeastern Brazil

Submitted by Nuzia Santos ([email protected]) on 2016-06-16T16:55:51Z No. of bitstreams: 1 ve_Grasielle_Pessoa_etal_Toxicological_CPqRR_2015.pdf: 202511 bytes, checksum: 80336ab7c4611a95956db4264270a2b6 (MD5)Approved for entry into archive by Nuzia Santos ([email protected]) on 2016-06-16T16:59:14Z (GMT) No. of bitstreams: 1 ve_Grasielle_Pessoa_etal_Toxicological_CPqRR_2015.pdf: 202511 bytes, checksum: 80336ab7c4611a95956db4264270a2b6 (MD5)Made available in DSpace on 2016-06-16T16:59:14Z (GMT). No. of bitstreams: 1 ve_Grasielle_Pessoa_etal_Toxicological_CPqRR_2015.pdf: 202511 bytes, checksum: 80336ab7c4611a95956db4264270a2b6 (MD5) Previous issue date: 2015Item withdrawn by Nuzia Santos ([email protected]) on 2016-07-01T18:51:37Z Item was in collections: CPqRR - Artigos de Periódicos (ID: 80) No. of bitstreams: 2 ve_Grasielle_Pessoa_etal_Toxicological_CPqRR_2015.pdf.txt: 23745 bytes, checksum: 8786b1015f4fce0542398a8a6fddb8aa (MD5) ve_Grasielle_Pessoa_etal_Toxicological_CPqRR_2015.pdf: 202511 bytes, checksum: 80336ab7c4611a95956db4264270a2b6 (MD5)Made available in DSpace on 2016-07-08T02:09:53Z (GMT). No. of bitstreams: 3 ve_Grasielle_Pessoa_etal_Toxicological_CPqRR_2015.pdf.txt: 23745 bytes, checksum: 8786b1015f4fce0542398a8a6fddb8aa (MD5) ve_Grasielle_Pessoa_etal_Toxicological_CPqRR_2015.pdf: 202511 bytes, checksum: 80336ab7c4611a95956db4264270a2b6 (MD5) license.txt: 2991 bytes, checksum: 5a560609d32a3863062d77ff32785d58 (MD5) Previous issue date: 2015Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, MG, Brasil.Secretaria de Saúde do Estado do Ceará. Fortaleza, CE, Brasil.Secretaria de Saúde do Estado de Minas Gerais. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Triatomíneos e Epidemiologia da Doença de Chagas. Belo Horizonte, MG, Brasil.INTRODUCTION: Triatoma brasiliensis is the species of greatest epidemiological relevance in the semi-arid region of Brazil. This species is predominantly found in domestic environments, and it has the ability to build large colonies with high levels of natural infection via Trypanosoma cruzi. Thus, T. brasiliensis is one of the most efficient transmitters of Chagas disease (CD) to humans. Despite household spraying with residual insecticides, many areas report persistent reinfestations for reasons that remain poorly understood. Therefore, this study sought to characterize the toxicological profile of deltamethrin in T. brasiliensis from areas with persistent reinfestation in State of Ceará, Brazil. METHODS: The susceptibility reference lineage (SRL) was derived from Umari. Serial dilutions of deltamethrin were prepared and applied to the dorsal abdomen of first instar nymphs. The control group received only pure acetone. Mortality was evaluated after 72h. Qualitative tests assessed mortality in response to a diagnostic dose of 1xLD99 (0.851 nanograms of active ingredient per treated nymph) of the SRL. RESULTS: The susceptibility profile characterization of the T. brasiliensis populations revealed 50% resistance ratios (RR50) that ranged from 0.32 to 1.21. The percentage of mortality in response to the diagnostic dose was 100%. CONCLUSIONS: We demonstrated that T. brasiliensis was highly susceptible to deltamethrin. The control difficulties found might be related to the recolonization of the triatomines originating from neighboring environments and the possible operational failures related to the process of spraying that enabled specimens less susceptible to deltamethrin to survive