Analysis of Music Products Under the Market Economy

In the institution of market economy, music products exist not only in the form of resting spirit, but also have the attributes of goods, which are integrations of emotions and money. This paper analyses the commodity attribute of music, and elaborates how to open the music market from several aspects like music creation, industrialized operation, how to develop and how to o product marketing and so on

The Analysis of Opera Teaching Methodology in Vocal Music Major in College

Opera plays an important role in the study of college students majoring in vocal music. From the analysis of opera works, musical structure, emotion and stage practice. This paper puts forward its own views and expounds how to teach opera

Evaluation of methods to decrease the discharge temperature of R32 scroll compressor

Recently, R32 has been considered as an important alternative in application of small to middle capacity air conditioner by many countries due to its advantages such as low global warming potential (GWP), favorable thermal properties, less refrigerant charge and low cost. However, the much increased discharge temperature of R32 compressor, as compared with the R22, becomes the main barrier affecting the wide and quick alternation. Refrigerant injection has proven to be effective in decreasing discharge temperature. In this work, three kinds of refrigerant injection technology used to decrease the discharge temperature of R32 scroll compressor are discussed, namely, two-phase suction, liquid injection and two-phase/gas injection. The detailed scroll compressor model proposed in previous work is modified and validated by experimental data of R32 scroll compressor. The potentials in decreasing discharge temperature of the three methods are investigated. The detailed performance comparisons are presented. The results indicate that the two-phase/gas injection achieves the best performance with the enhancement of cooling capacity by 14.2% and increase in COP by 8.1%

Three-dimensional reconstruction optimization of tunnel face and intelligent extraction of discontinuity orientation based on binocular stereo vision

In the process of grading and dynamically optimizing the design and construction parameters of the surrounding rock mass of a rock tunnel face, efficiently and accurately acquiring the geometrical parameters of the rock discontinuities is an important basic task. To address the problems of time consuming, low accuracy, and high danger associated with traditional methods of obtaining the structural information of rock mass, this paper proposes a method for three-dimensional reconstruction and intelligent information extraction of tunnel face based on binocular stereo vision (BSV). First, the parallel binocular device with a single camera was improved, calibrated using the checkerboard calibration method. By integrating with the semi-global matching algorithm, the BSV based method for the three-dimensional reconstruction of the rock mass of the tunnel face was optimized. Furthermore, based on the results from on-site engineering applications, this study leveraged two parameters, point cloud density and algorithm runtime, to determine the optimal values for the disparity range and window size parameters within the semi-global stereo matching algorithm. This enhancement improved the performance of the 3D reconstruction method based on binocular stereo vision. Finally, efficient and refined intelligent methods for extracting structural parameters of the rock mass were proposed based on k-nearest neighbor search and kernel density estimation. The research results can provide reliable technical support for the intelligent and efficient acquisition of rock mass structural information in rock tunnel engineering faces

Does Serum Vitamin D Level Affect COVID-19 Infection and Its Severity?-A Case-Control Study

Background: As effective medication to treat COVID-19 is currently unavailable, preventive remedies may be particularly important. Objective: To examine the relationship between serum 25-hydroxy vitamin D (25(OH)D) level and COVID-19 infection, its severity, and its clinical case characteristics. Methods: This case-control study compared serum 25(OH)D levels and rates of vitamin D deficiency (VDD) between 80 healthy controls and 62 patients diagnosed with COVID-19 and admitted to Guangxi People’s Hospital, China, 2/16/2020–3/16/2020. Cases were categorized into asymptomatic, mild/moderate, and severe/critical disease. Logistic regression analysis was conducted to examine the associations between 25(OH)D level, or VDD, and case status/severity of COVID-19 while controlling for demographics and comorbidities. A threshold level of vitamin D for conveying COVID-19 risk was estimated. Results: Severe/critical COVID-19 cases were significantly older and had higher percentages of comorbidity (renal failure) compared to mild cases. The serum 25(OH)D concentration in COVID-19 patient was much lower than that in healthy control. And 25(OH)D level was the lowest in severe/ critical cases, compared with mild cases. In further, significantly higher rates of VDD were found in COVID-19 cases (41.9%) compared to healthy controls (11.1%). And VDD was the greatest in severe/critical cases (80%), compared with mild cases (36%). These statistically significant associations remained even after controlling for demographics and comorbidities. A potential threshold of 25(OH)D (41.19nmol/L) to protect against COVID-19 was identified. Conclusion: Elderly and people with comorbidities were susceptible to severe COVID-19 infection. VDD was a risk factor for COVID-19, especially for severe/critical cases. While further confirmation is needed, vitamin D supplementation may have prevention or treatment potential for COVID- 19 disease

Expression of MK-1 and RegⅣ and its clinicopathological significances in the benign and malignant lesions of gallbladder

<p>Abstract</p> <p>Background</p> <p>To study the expression of MK-1 and RegⅣ and to detect their pathological significances in benign and malignant lesions of gallbladder.</p> <p>Methods</p> <p>The expression of MK-1 and RegⅣ was detected by immunohistochemical method in paraffin-embedded sections of surgical resected specimens from gallbladder adenocarcinoma (n = 108), peritumoral tissues (n = 46), adenomatous polyp (n = 15), and chronic cholecystitis (n = 35).</p> <p>Results</p> <p>The positive rate of MK-1 or RegⅣ expression was significantly higher in gallbladder adenocarcinoma than that in peritumoral tissues (χ²_MK-1= 18.76, <it>P </it>< 0.01; χ²_RegⅣ= 9.92, <it>P </it>< 0.01), denomatous polyp (χ²_MK-1= 9.49, <it>P </it>< 0.01; χ²_RegⅣ= 8.59, <it>P </it>< 0.01) and chronic cholecystitis (χ²_MK-1= 24.11, <it>P </it>< 0.01; χ²_RegⅣ= 19.24, <it>P </it>< 0.01). The positive cases of MK-1 and/or RegⅣ in the benign lesions showed moderately- or severe-atypical hyperplasia of gallbladder epitheli. The positive rates of MK-1 were significantly higher in the cases of well-differentiated adenocarcinoma, no-metastasis of lymph node, and no-invasiveness of regional tissues than those in the ones of differentiated adenocarcinoma, metastasis of lymph node, and invasiveness of regional tissues in gallbladder adenocarcinoma (<it>P </it>< 0.05 or <it>P </it>< 0.01). On the contrary, the positive rates of RegⅣ were significantly lower in the cases of well-differentiated adenocarcinoma, no-metastasis of lymph node, and no-invasiveness of regional tissues than those in the ones of differentiated adenocarcinoma, metastasis of lymph node, and invasiveness of regional tissues in gallbladder adenocarcinoma (<it>P </it>< 0.05 or <it>P </it>< 0.01). Univariate Kaplan-Meier analysis showed that decreased expression of MK-1 (<it>P </it>= 0.09) or increased expression of RegⅣ (<it>P </it>= 0.003) was associated with decreased overall survival. Multivariate Cox regression analysis showed that decreased expression of MK-1 (<it>P </it>= 0.033) and increased expression of RegⅣ (<it>P </it>= 0.008) was an independent prognostic predictor in gallbladder adenocarcinoma.</p> <p>Conclusions</p> <p>The expression of MK-1 and/or RegⅣ might be closely related to the carcinogenesis, clinical biological behaviors, and prognosis of gallbladder adenocarcinoma.</p