Model architecture for associative memory in a neural network of spiking neurons

AbstractA synaptic connectivity model is assembled on a spiking neuron network aiming to build up a dynamic pattern recognition system. The connection architecture includes gap junctions and both inhibitory and excitatory chemical synapses based on Hebb’s hypothesis. The network evolution resulting from external stimulus is sampled in a properly defined frequency space. Neurons’ responses to different current injections are mapped onto a subspace using Principal Component Analysis. Departing from the base attractor, related to a quiescent state, different external stimuli drive the network to different fixed points through specific trajectories in this subspace

Towards a genome-wide transcriptogram: the Saccharomyces cerevisiae case

A genome modular classification that associates cellular processes to modules could lead to a method to quantify the differences in gene expression levels in different cellular stages or conditions: the transcriptogram, a powerful tool for assessing cell performance, would be at hand. Here we present a computational method to order genes on a line that clusters strongly interacting genes, defining functional modules associated with gene ontology terms. The starting point is a list of genes and a matrix specifying their interactions, available at large gene interaction databases. Considering the Saccharomyces cerevisiae genome we produced a succession of plots of gene transcription levels for a fermentation process. These plots discriminate the fermentation stage the cell is going through and may be regarded as the first versions of a transcriptogram. This method is useful for extracting information from cell stimuli/responses experiments, and may be applied with diagnostic purposes to different organisms

1998] \Exploring collective behaviors with a multi-attractor quartic map

Abstract We simulate a 2D coupled map lattice formed by individual units consisting of a multi-attractor quartic map. We show that the interesting recently discovered non-trivial collective behaviors (where macroscopic quantities show well-deÿned, usually regular, temporal evolution in spite of the presence of local disorder in space and time) also exist, over wide parameter domains, in the presence of local periodic order, in systems having more realistic units allowing coexistence of more than one attractor

Synchronization regimes in a map-based model neural network

The dynamical activity of a neural network model composed of electrically connected map-based neurons is investigated. After detailing the behavior of the isolated neuron for a wide parameter range, collective network states are depicted using the activity, spatial correlation and time phase distribution as measures. A detailed discussion on the stability of global and partial synchronization states is presented