“Perversity, Futility, Jeopardy”: An Economic Analysis of the Attack on Gun Control

A relatively new way for utilizing the thermal performance of heat pipes is to use nanofluids as working fluids in the heat pipes. Heat pipes are effective heat transfer devices in which the nanofluid operates in the two phases, evaporation and condensation. The heat pipe transfers the heat supplied in e.g. a laptop, from the evaporator to condenser part. Nanofluids are mixtures consisting of nanoparticles (e.g. nano-sized silver particles) and a base fluid (e.g. water). The aim of this bachelor’s thesis has been to examine the effect of nanofluids on heat pipes on the subject of temperature parameters and thermal resistance in the heat pies, through findings in literature and an applied model. The study, based on literature and an applied model, found that higher particle conductivity and higher concentration of nanoparticles consequently decrease the thermal resistance in the heat pipes, resulting in an enhanced thermal performance of the heat pipes with nanofluids as working fluids. It is however concluded that difficulties in finding the optimal synthesis of nanofluids, the concentration level of nanoparticles and the filling ratio of nanofluids in heat pipes, set bounds to the commercial use of nanofluids in heat pipes. It is suggested that, in order to enhance the heat transfer performance of nanofluids in heat pipes, to conduct further research concerning e.g. synthesis of nanofluids and concentration level of nanoparticles in nanofluids

From Harm to Robustness: A Principled Approach to Vice Regulation

John Stuart Mill’s harm principle maintains that adult behavior cannot justifiably be subject to social coercion unless the behavior involves harm or a significant risk of harm to non-consenting others. The absence of harms to others, however, is one of the distinguishing features of many manifestations of “vices” such as the consumption of alcohol, nicotine, recreational drugs, prostitution, pornography, and gambling. It is with respect to vice policy, then, that the harm principle tends to be most constraining, and some current vice controls, such as prohibitions on drug possession and prostitution, violate Mill’s precept. In the vice arena, we seem to be willing to accept social interference with what Mill termed “self-regarding” behavior. But does that willingness then imply that any social intervention into private affairs is justifiable, that the government has just as much right to outlaw Protestantism, or shag carpets, or spicy foods, as it does to outlaw drugs? In this paper I argue that advances in neuroscience and behavioral economics offer strong evidence that vices and other potentially addictive goods or activities frequently involve less-than-rational choices, and hence are exempt from the full force of the harm principle. As an alternative guide to vice policy, and following some guidance from Mill, I propose the “robustness principle”: public policy towards addictive or vicious activities engaged in by adults should be robust with respect to departures from full rationality. That is, policies should work pretty well if everyone is completely rational, and policies should work pretty well even if many people are occasionally (or frequently) irrational in their vice-related choices. The harm and robustness principles cohere in many ways, but the robustness principle offers more scope for policies that try to direct people “for their own good,” without opening the door to tyrannical inroads upon self-regarding behavior

"SMART" GUNS: A TECHNOLOGICAL FIX FOR REGULATING THE SECONDARY MARKET

A "personalized" or "smart" gun will not fire unless it is being used by an authorized individual. Such guns have the potential to reduce the negative externalities of gun ownership while preserving the benefits. Ongoing efforts to develop practical "smart" designs make it timely to consider regulations that would favor or mandate them in the market for new guns. The likely consequences would depend on the design details, in particular the costs of transferring the "key" to firing such guns. With an "ideal" design, transferring the key would require special equipment that could be monitored by appropriate authorities. The result would be to block thefts and other transfers of such guns in the secondary market and, in the long run, reduce access by individuals who are proscribed from possessing a gun. Personalized guns, therefore, could make existing firearms regulations more effective and reduce the social costs associated with gun misuse. Though personalized guns have advantages relative to standard guns in a wide variety of situations, some of the potential benefits of personalized guns could be captured through alternative policy measures. Copyright 2002 Western Economic Association International.

Patients with elevation in both serum ferritin and CRP have the poorest response to trastuzumab-containing therapy.

<p>Kaplan-Meier analysis of overall survival (A) and progression-free survival (B) in trastuzumab-treated patients stratified by their CRP and serum ferritin levels. High CRP (>7.25 mg/l); High Ferritin (>250 ng/ml).</p