3,123 research outputs found

    Identifying low-carb dieter\u27s characteristics and their diet practices during business travels

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    The low carbohydrate diet phenomenon has recently evolved to such an extent that there is now extensive consumer demand for carbohydrate conscious dining options. The power of the recent movement is impacting all facets of the hospitality industry including restaurants, hotels, airlines and conventions. The purpose of this study is to identify business travelers\u27 low carbohydrate diet practices and to understand their experiences with low-carbohydrate menus during business trips; This research identified low-carb dieters\u27 characteristics and their diet practices during business trips. Results indicated that, compared to other dieters, low-carb dieters are older, more likely to be overweight or obese, more concerned with weight loss as a reason for dieting, and more likely to follow their diets and seek high quality low-carb foods when traveling. In addition, the findings indicate that the respondents\u27 experiences with low-carb foods during their business trips are influential in predicting their behavior regarding following a diet in the future. This study suggests that the food, restaurant, and hotel industry should understand business travelers\u27 diet practices and food preferences at meetings. The findings imply that all facets of the hospitality industry interfacing with business travelers need to continue development of low-carb menu offerings if they are to meet business travelers\u27 needs

    Special Apparel Needs of Consumers with Visual Impairments

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    The purpose of this study is to understand apparel consumers with visual impairments in terms of their apparel selection and shopping needs. The apparel needs of disabled consumers, specifically consumers with visual impairments, have not been thoroughly investigated (Chang et al., 2014). It is not known to what extent they differ, if at all, from consumers who are not visually impaired. Thus, this research provides insight into their apparel needs so that apparel manufacturers and retailers can better meet the needs of these disabled consumers

    From fandom to tourism: An examination of self-~expansion theory

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    In recent years, pop-culture tourism, in which individuals travel to destinations made famous through pop-culture or relative media themes, has come into the spotlight. The new market segment induced by pop-culture has created a specialized but dedicated consumer, called a fan. This study examined the impact of pop-stars on a destination from the perspective of fans. Specifically, the research investigated whether fans at different degrees of fandom had different travel attitudes and behaviors with regard to motivation, satisfaction, attachment, and loyalty in the destination context by applying self-expansion theory. In particular, Korean pop-star\u27s fans were chosen as the study example of Korean pop-culture. This research provided empirical support for the impact of fandom on tourism. Results of the study revealed a new characteristic of fans, a high level of self-expansion. Fans\u27 self-expansion was significant in influencing their fandom and travel motivation. As a result, a high degree of fandom had a significant effect on travel satisfaction and destination loyalty. Given the growing importance of pop-culture tourism, this research is among the first studies to investigate the impact of fandom on tourism, providing new insights in understanding this niche segment from the pop-culture fans\u27 perspective. The examination of self-expansion theory on fandom and tourism has helped to bridge the link between a fan and a destination, extending the literature on destination studies, and suggesting meaningful implications for destination marketers. The findings of this study suggest that future research continue to investigate destination markets with different and/or broader contexts using diverse research approaches

    Cug2 is essential for normal mitotic control and CNS development in zebrafish.

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    Background: We recently identified a novel oncogene, Cancer-upregulated gene 2 (CUG2), which is essential for kinetochore formation and promotes tumorigenesis in mammalian cells. However, the in vivo function of CUG2 has not been studied in animal models. Results: To study the function of CUG2 in vivo, we isolated a zebrafish homologue that is expressed specifically in the proliferating cells of the central nervous system (CNS). Morpholino-mediated knockdown of cug2 resulted in apoptosis throughout the CNS and the development of neurodegenerative phenotypes. In addition, cug2-deficient embryos contained mitotically arrested cells displaying abnormal spindle formation and chromosome misalignment in the neural plate. Conclusions: Therefore, our findings suggest that Cug2 is required for normal mitosis during early neurogenesis and has functions in neuronal cell maintenance, thus demonstrating that the cug2 deficient embryos may provide a model system for human neurodegenerative disorders

    Portulaca oleracea Ameliorates Diabetic Vascular Inflammation and Endothelial Dysfunction in db/db Mice

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    Type 2 diabetes is associated with significantly accelerated rates of micro- and macrovascular complications such as diabetic vascular inflammation and endothelial dysfunction. In the present study, we investigated the protective effect of the aqueous extract of Portulaca oleracea L. (AP), an edible plant used as a folk medicine, on diabetic vascular complications. The db/db mice were treated with AP (300 mg/kg/day, p.o.) for 10 weeks, and AP treatment markedly lowered blood glucose, plasma triglyceride, plasma level of LDL-cholesterol, and systolic blood pressure in diabetic db/db mice. Furthermore, AP significantly increased plasma level of HDL-cholesterol and insulin level. The impairment of ACh- and SNP-induced vascular relaxation of aortic rings were ameliorated by AP treatment in diabetic db/db mice. This study also showed that overexpression of VCAM-1, ICAM-1, E-selectin, MMP-2, and ET-1 were observed in aortic tissues of untreated db/db mice, which were significantly suppressed by treatment with AP. We also found that the insulin immunoreactivity of the pancreatic islets remarkably increased in AP treated db/db mice compared with untreated db/db mice. Taken together, AP suppresses hyperglycemia and diabetic vascular inflammation, and prevents the development of diabetic endothelial dysfunction for the development of diabetes and its vascular complications

    Risk of Atrial Fibrillation and Adverse Outcomes in Patients With Cardiac Implantable Electronic Devices.

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    Background and objectives: Comprehensive epidemiological data are lacking on the incident atrial fibrillation (AF) in patients with cardiac implantable electronic devices (CIEDs). This study aimed to examine the incidence, risk factors, and AF-related adverse outcomes of patients with CIEDs.Methods: This was an observational cohort study that analyzed patients without prevalent AF who underwent CIED implantation in 2009-2018 using a Korean nationwide claims database. The subjects were divided into three groups by CIED type and indication: pacemaker (n=21,438), implantable cardioverter defibrillator (ICD)/cardiac resynchronization therapy (CRT) with heart failure (HF) (n=3,450), and ICD for secondary prevention without HF (n=2,146). The incidence of AF, AF-associated predictors, and adverse outcomes were evaluated.Results: During follow-up, the incidence of AF was 4.3, 7.3, and 5.1 per 100 person-years in the pacemaker, ICD/CRT with HF, and ICD without HF cohorts, respectively. Across the three cohorts, older age and valvular heart disease were commonly associated with incident AF. Incident AF was consistently associated with an increased risk of ischemic stroke (3.8-11.4-fold), admission for HF (2.6-10.5-fold), hospitalization for any cause (2.4-2.7-fold), all-cause death (4.1-5.0-fold), and composite outcomes (3.4-5.7-fold). Oral anticoagulation rates were suboptimal in patients with incident AF (pacemaker, 51.3%; ICD/CRT with HF, 51.7%; and ICD without HF, 33.8%, respectively).Conclusions: A substantial proportion of patients implanted CIED developed newly diagnosed AF. Incident AF was associated with a higher risk of adverse events. The importance of awareness, early detection, and appropriate management of AF in patients with CIED should be emphasized

    KINEMATIC ANALYSIS OF GOLF SWING PERFORMED WITH INTENDED LATE HITTING

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    The purposes of this study were to analyze and compare the kinematic parameters for standard and purpose golf swings. The purpose golf swing is characterized as intended late hitting and increase displacement of ball through the air (carry). Twenty-five male college golfers were recruited as sUbjects and Science eye field 3 camera system was used to measure the parameters of deterministic model. Paired t-test was used to compare between two different golf swings and correlation coefficients between selected parameters and carry were also computed. As results, a significant difference between standard and purpose golf swings was found in terms of increasing carry. Coefficients of correlation indicated that post-impact ball velocity, pre-impact club head velocity, and meet rate were positively correlated with carry. However, backspin, and angle of release were negatively correlated with carry. These results represented that the parameters of deterministic model were very useful indicators to determine performance and the purpose swing is beneficial to increase carry

    Fabrication of a spherical inclusion phantom for validation of magnetic resonance-based magnetic susceptibility imaging

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    © 2019 Kim et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Fabrication of a spherical multi-compartment MRI phantom is demonstrated that can be used to validate magnetic resonance (MR)-based susceptibility imaging reconstruction. The phantom consists of a 10 cm diameter gelatin sphere that encloses multiple smaller gelatin spheres doped with different concentrations of paramagnetic contrast agents. Compared to previous multi-compartment phantoms with cylindrical geometry, the phantom provides the following benefits: (1) no compartmental barrier materials are used that can introduce signal voids and spurious phase; (2) compartmental geometry is reproducible; (3) spherical susceptibility boundaries possess a ground-truth analytical phase solution for easy experimental validation; (4) spherical geometry of the overall phantom eliminates background phase due to air-phantom boundary in any scan orientation. The susceptibility of individual compartments can be controlled independently by doping. During fabrication, formalin crosslinking and water-proof surface coating effectively blocked water diffusion between the compartments to preserve the phantom’s integrity. The spherical shapes were realized by molding the inner gel compartments in acrylic spherical shells, 3 cm in diameter, and constructing the whole phantom inside a larger acrylic shell. From gradient echo images obtained at 3T, we verified that the phantom produced phase images in agreement with the theoretical prediction. Factors that limit the agreement include: air bubbles trapped at the gel interfaces, imperfect magnet shimming, and the susceptibility of external materials such as the phantom support hardware. The phantom images were used to validate publicly available codes for quantitative susceptibility mapping. We believe that the proposed phantom can provide a useful testbed for validation of MR phase imaging and MR-based magnetic susceptibility reconstructio
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