50 research outputs found
Title page cGMP-Selective Phosphodiesterase Inhibitors Stimulate Mitochondrial Biogenesis and Promote Recovery from AKI
- Publication venue
- Publication date
- 24/04/2020
- Field of study
Multiple Wolbachia strains provide comparative levels of protection against dengue virus infection in Aedes aegypti.
- Author
- Carrington Lauren B
- Flores Heather A
- Le Anh Huy Huynh
- O'Donnell Tanya B
- O'Neill Scott L
- Simmons Cameron P
- Taneja de Bruyne Jyotika
- Thanh Phong Nguyen
- Thi Dui Le
- Thi Giang Nguyen
- Thi Hue Kien Duong
- Thi Le Duyen Huynh
- Thi Long Vo
- Thi Thuy Van Huynh
- Thi Van Thuy Nguyen
- Thi Xuan Trang Huynh
- Thuy Vi Tran
- Tuyet Nhu Vu
- Van Vinh Chau Nguyen
- Wills Bridget
- Publication venue
- PLoS Pathog
- Publication date
- 01/04/2020
- Field of study
The insect bacterium Wolbachia pipientis is being introgressed into Aedes aegypti populations as an intervention against the transmission of medically important arboviruses. Here we compare Ae. aegypti mosquitoes infected with wMelCS or wAlbB to the widely used wMel Wolbachia strain on an Australian nuclear genetic background for their susceptibility to infection by dengue virus (DENV) genotypes spanning all four serotypes. All Wolbachia-infected mosquitoes were more resistant to intrathoracic DENV challenge than their wildtype counterparts. Blocking of DENV replication was greatest by wMelCS. Conversely, wAlbB-infected mosquitoes were more susceptible to whole body infection than wMel and wMelCS. We extended these findings via mosquito oral feeding experiments, using viremic blood from 36 acute, hospitalised dengue cases in Vietnam, additionally including wMel and wildtype mosquitoes on a Vietnamese nuclear genetic background. As above, wAlbB was less effective at blocking DENV replication in the abdomen compared to wMel and wMelCS. The transmission potential of all Wolbachia-infected mosquito lines (measured by the presence/absence of infectious DENV in mosquito saliva) after 14 days, was significantly reduced compared to their wildtype counterparts, and lowest for wMelCS and wAlbB. These data support the use of wAlbB and wMelCS strains for introgression field trials and the biocontrol of DENV transmission. Furthermore, despite observing significant differences in transmission potential between wildtype mosquitoes from Australia and Vietnam, no difference was observed between wMel-infected mosquitoes from each background suggesting that Wolbachia may override any underlying variation in DENV transmission potential
Comparative Susceptibility of Aedes albopictus and Aedes aegypti to Dengue Virus Infection After Feeding on Blood of Viremic Humans: Implications for Public Health.
- Author
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 17/03/2015
- Field of study
Aedes albopictus is secondary to Aedes aegypti as a vector of dengue viruses (DENVs) in settings of endemicity, but it plays an important role in areas of dengue emergence. This study compared the susceptibility of these 2 species to DENV infection by performing 232 direct blood-feeding experiments on 118 viremic patients with dengue in Vietnam. Field-derived A. albopictus acquired DENV infections as readily as A. aegypti after blood feeding. Once infected, A. albopictus permitted higher concentrations of DENV RNA to accumulate in abdominal tissues, compared with A. aegypti. However, the odds of A. albopictus having infectious saliva were lower than the odds observed for A. aegypti (odds ratio, 0.70; 95% confidence interval, .52-.93). These results quantitate the susceptibility of A. albopictus to DENV infection and will assist parameterization of models for predicting disease risk in settings where A. albopictus is present
Evaluation of individual and ensemble probabilistic forecasts of COVID-19 mortality in the United States
- Author
- Abbott Sam
- Abernethy Neil F.
- Adee Madeline
- Adhikari Bijaya
- Arik Sercan O.
- Asplund John
- Ayer Turgay
- Baccam Prasith
- Baek Jackie
- Baer Thomas M.
- Ban Xuegang
- Bannur Nayana
- Barber Ryan
- Baxter Arden
- Ben-Nun Michal
- Bennouna Mohammed Amine
- Bertsimas Dimitris
- Bian Jiang
- Biegel Hannah
- Bien Jacob
- Biggerstaff Matthew
- Bosse Nikos I.
- Bracher Johannes
- Brennen Andrea
- Brooks Logan
- Burant John C.
- Cao Wei
- Castro Rivadeneira Alvaro J.
- Castro Lauren
- Cavany Sean
- Cegan Jeffrey C.
- Celi Leo A.
- Chen Jinghui
- Chen Samuel
- Chen YangQuan
- Chhatwal Jagpreet
- Chinazzi Matteo
- Corsetti Sabrina M.
- Cramer Estee Y.
- Cui Jiaming
- Dahan Maytal
- Dalgic Ozden O.
- Davis Jessica T.
- Della Penna Nicolas
- Dent Juan
- DesRoches David
- Dettwiller Ian D.
- Deva Ayush
- Drake John M.
- Dusenberry Mike
- Eisenberg Marisa C.
- England William P.
- Epshteyn Arkady
- España Guido
- Fairchild Geoffrey
- Falb Karl
- Faraone Stephen V.
- Farias Vivek
- Farthing Matthew W.
- Forli Pedro
- Fox Spencer
- Funk Sebastian
- Gaither Kelly
- Gakidou Emmanuela
- Gao Lei
- Gao Liyao
- Gao Zhifeng
- Gardner Lauren
- George Glover E.
- Georgescu Andreea
- Gerding Aaron
- Gibson Graham Casey
- Gneiting Tilmann
- Grantz Kyra H.
- Green Alden
- Gu Quanquan
- Gu Youyang
- Gu Zhiling
- Guertin Stephanie L.
- Guo Lihong
- Gurung Heidi L.
- Hamory Bruce
- Hay Simon I.
- Hellewell Joel
- Hess Jonathan
- Hill Alison L.
- Ho Lam Si Tung
- Hong Qi-Jun
- House Katie H.
- Hu Addison J.
- Huang Yitao
- Huang Yuxin
- Hulme-Lowe Christopher
- Hunter Robert H.
- Huynh Huong
- Jadbabaie Ali
- Jahja Maria
- Jain Sansiddh
- Jayawardena Dasuni
- Jin Xiaoyong
- Johansson Michael A.
- Kalantari Rahi
- Kaminsky Joshua
- Kaminsky Kathryn
- Kanal Elli
- Kanji Abdul H.
- Karlen Dean
- Keegan Lindsay T.
- Keskinocak Pinar
- Khandelwal Ayush
- Kim Myungjin
- Kinsey Matt
- Kong Stanley
- Koyluoglu Ugur
- Kraus Andrea
- Kraus David
- Kulkarni Mihir
- Kyriakides Christina
- Lachmann Michael
- Ladd Mary A.
- Lafferty Brandon
- Lauer Stephen A.
- Lavista Ferres Juan
- Le Khoa
- Le Long T.
- Lee Elizabeth C.
- Lega Joceline
- Leis Helen
- Lemaitre Joseph C.
- Lessler Justin
- Levi Retsef
- Li Chaozhuo
- Li Chun-Liang
- Li Michael L.
- Li Xinyi
- Lim Steve
- Linas Benjamin P.
- Linkov Igor
- Liu Tie-Yan
- Lopez Velma K.
- Ma Yian
- Marshall Maximilian
- Martin Emily T.
- Mayo Michael L.
- McCauley Ella
- McConnell Steve
- McDonald Daniel
- Meakin Sophie R.
- Meredith Hannah R.
- Merugu Srujana
- Meyers Lauren Ancel
- Michaud Isaac
- Milliken John
- Moloney Michael
- Moore Sean
- Morgan James
- Morley Christopher P.
- Mu Kunpeng
- Mueller Peter
- Mullany Luke C.
- Murray Chris
- Myers Robert L.
- Mühlemann Anja
- Nagraj V. P.
- Narasimhan Balasubramanian
- Niemi Jarad
- Nirgudkar Ninad
- Nixon Kristen
- Nze-Ndong David
- Oidtman Rachel
- Oruc Buse Eylul
- Osthus Dave
- Ozcan Gokce
- O’Dea Eamon B.
- Pagano Robert
- Parno Matthew D.
- Pastore y Piontti Ana
- Pei Sen
- Perakis Georgia
- Perez-Saez Javier
- Perkins Alex
- Pfister Tomas
- Pigott David
- Piwonka Noah
- Politsch Collin
- Prakash B. Aditya
- Rainwater-Lovett Kaitlin
- Rajanala Samyak
- Raval Alpan
- Ravi Matt
- Ray Evan L.
- Reich Nicholas G.
- Reiner Robert C.
- Riley Pete
- Riley Steven
- Rodríguez Alexander
- Rowland Michael A.
- Rumack Aaron
- Salekin Asif
- Sarker Arnab
- Sava Dario
- Schrader Chris
- Schwarz Tom
- Scott James G.
- Serban Nicoleta
- Shah Apurv
- Shah Devavrat
- Shah Sam
- Shakhnovich Elizabeth
- Shaman Jeffrey
- Sheldon Daniel
- Sherratt Katharine
- Shi Yunfeng
- Shin Lauren
- Shingi Siddhant
- Siegel Daniel
- Simon Noah
- Singhvi Divya
- Sinha Deeksha
- Sinha Rajarishi
- Skali Lami Omar
- Slayton Rachel B.
- Smith Claire P.
- Soni Saksham
- Spantidakis Ioannis
- Spatz Ryan
- Srivastava Ajitesh
- Stage Steven A.
- Stark Ariane
- Stiefeling Chris
- Suchoski Bradley T.
- Sundar Saketh
- Tabassum Anika
- Tallaksen Katharine
- Tazi Bouardi Hamza
- Tec Mauricio
- Thayaparan Leann
- Tibshirani Rob
- Tibshirani Ryan J.
- Tiwari Avtansh
- Tran Quoc T.
- Truelove Shaun A.
- Trump Benjamin D.
- Tsai Thomas
- Tsiourvas Asterios
- Turner Stephen D.
- Turtle James A.
- van de Walle Axel
- Ventura Valerie
- Vespignani Alessandro
- Walker Jo W.
- Walraven Robert
- Wang Dongliang
- Wang Guannan
- Wang Lily
- Wang Lingxiao
- Wang Qinxia
- Wang Yijin
- Wang Yu-Xiang
- Wang Yuanjia
- Wang Yueying
- Wasserman Larry
- Wattanachit Nutcha
- White Jerome
- Wilde Joshua
- Wilkinson Barrie
- Wills Josh
- Wilson Shelby
- Wolfinger Russ
- Wong Alexander
- Woody Spencer
- Wu Dongxia
- Xiao Jade
- Xie Jiajia
- Xie Shanghong
- Xie Xing
- Xiong Xinyue
- Xu Pan
- Yamana Teresa K.
- Yan Xifeng
- Yoder Nate
- Yoon Jinsung
- Yu Rose
- Yu Shan
- Zeng Donglin
- Zhang Leyou
- Zhang Shun
- Zhang Weitong
- Zhang-James Yanli
- Zhao Yanting
- Zheng Andrew
- Zheng Shun
- Zhou Mingyuan
- Zorn Martha W.
- Zou Difan
- Publication venue
- National Academy of Sciences
- Publication date
- 04/05/2022
- Field of study
Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. Starting in April 2020, the US COVID-19 Forecast Hub (https://covid19forecasthub.org/) collected, disseminated, and synthesized tens of millions of specific predictions from more than 90 different academic, industry, and independent research groups. A multimodel ensemble forecast that combined predictions from dozens of groups every week provided the most consistently accurate probabilistic forecasts of incident deaths due to COVID-19 at the state and national level from April 2020 through October 2021. The performance of 27 individual models that submitted complete forecasts of COVID-19 deaths consistently throughout this year showed high variability in forecast skill across time, geospatial units, and forecast horizons. Two-thirds of the models evaluated showed better accuracy than a naïve baseline model. Forecast accuracy degraded as models made predictions further into the future, with probabilistic error at a 20-wk horizon three to five times larger than when predicting at a 1-wk horizon. This project underscores the role that collaboration and active coordination between governmental public-health agencies, academic modeling teams, and industry partners can play in developing modern modeling capabilities to support local, state, and federal response to outbreaks
The United States COVID-19 Forecast Hub dataset
- Author
- Abbott Sam
- Abu-Mostafa Yaser
- Adee Madeline
- Adhikari Bijaya
- Adiga Aniruddha
- Arik Sercan O.
- Asplund John
- Ayer Turgay
- Baccam Prasith
- Baek Jackie
- Baer Thomas M.
- Ban Xuegang
- Bannur Nayana
- Barber Ryan
- Bathwal Rahil
- Baxter Arden
- Bejar Benjamín
- Belov Artur A.
- Ben-Nun Michal
- Bennouna Amine
- Berlin Abraham
- Bertsimas Dimitris
- Bhatia Sangeeta
- Bian Jiang
- Biegel Hannah
- Bien Jacob
- Biggerstaff Matthew
- Bosch Jurgen
- Bosse Nikos I.
- Bouardi Hamza Tazi
- Bracher Johannes
- Brennen Andrea
- Brenner Michael
- Brooks Logan
- Budzinski Jozef
- Burant John C.
- Cao Duy
- Cao Wei
- Castro Lauren
- Cavany Sean
- Cegan Jeffrey C.
- Celi Leo A.
- Chang Nicholas A.
- Chattopadhyay Ishanu
- Chen Jinghui
- Chen Samuel
- Chen YangQuan
- Chen Ye
- Chen Yixian
- Chhatwal Jagpreet
- Chiang Wen-Hao
- Chinazzi Matteo
- Chintanippu Krishna
- Chitta Pavan
- Cho Jae H.
- Choirat Christine
- Chow Carson C.
- Coram Marc
- Cornell Matthew
- Corsetti Sabrina M.
- Cramer Estee Y.
- Cui Jiaming
- Dahan Maytal
- Dalgic Ozden O.
- Davis Jessica T.
- DesRoches David
- Dettwiller Ian D.
- Deva Ayush
- Drake John M.
- Dusenberry Mike
- Edwards Jessie K.
- Eisenberg Marisa C.
- England William P.
- Epshteyn Arkady
- Erickson Anne
- España Guido
- Fairchild Geoffrey
- Falb Karl
- Faraone Stephen V.
- Farias Vivek
- Farthing Matthew W.
- Ferres Juan Lavista
- Flahault Antoine
- Fong Chung-Yan
- Forli Pedro
- Fox Spencer
- Funk Sebastian
- Gaikedu Emmanuela
- Gaither Kelly
- Galasso Joseph
- Gandhi Parth D.
- Gao Junyi
- Gao Lei
- Gao Liyao
- Gao Zhifeng
- Gardner Lauren
- George Glover E.
- Georgescu Andreea
- Gerding Aaron
- Gerkin Richard C.
- Gibson Graham Casey
- Glass Lucas
- Gneiting Tilmann
- Goel Sumit
- Gowda Jethin
- Grantz Kyra H.
- Green Alden
- Gu Quanquan
- Gu Youyang
- Gu Zhiling
- Guertin Stephanie L.
- Guo Lihong
- Gurung Heidi L.
- Hamory Bruce
- Hay Simon
- Hellewell Joel
- Hess Jonathan
- Hill Alison L.
- Hlavacek William
- Ho Lam
- Hong Qi-Jun
- House Katie
- Hu Addison J.
- Huang Yi
- Huang Yitao
- Huang Yuxin
- Hulme-Lowe Christopher
- Hulse Juan Dent
- Hunter Robert H.
- Hurt Benjamin
- Hussain Fazle
- Huynh Huong
- Ibrahim Mark
- Ivy Julie S.
- Jadbabaie Ali
- Jahja Maria
- Jain Chaman
- Jain Chandini
- Jain Sansiddh
- Jayawardena Dasuni
- Jin Qixuan
- Jin Xiaoyong
- Jivane Viresh
- Jo Areum
- Jo HyeongChan
- Johansson Michael A.
- Joshi Keya
- Kalantari Rahi
- Kaminsky Joshua
- Kaminsky Kathryn
- Kanal Elli
- Kanji Abdul Hannan
- Karimzadeh Morteza
- Karlen Dean
- Keegan Lindsay T.
- Keskinocak Pinar
- Khan Zeina
- Khandelwal Ayush
- Khurana Ankita
- Kim Juhyun
- Kim Myungjin
- Kinsey Matt
- Klein Ellen
- Koyluoglu Ugur
- Kraus Andrea
- Kraus David
- Krymova Ekaterina
- Kulkarni Mihir
- Kulkarni Pranav
- Kumar Ajay
- Kyriakides Christina
- Lachmann Michael
- Lacroix Timothee
- Ladd Mary A.
- Lafferty Brandon
- Lakhani Anshul
- Lami Omar Skali
- Lauer Stephen A.
- Le Khoa
- Le Long T.
- Le Matthew
- Lee Elizabeth C.
- Lee Gavin
- Lega Joceline
- Leis Helen
- Lemaitre Joseph C.
- Lessler Justin
- Levi Retsef
- Lewis Bryan
- Li Chaozhuo
- Li Chun-Liang
- Li Michael L.
- Li Xinyi
- Liao Jason
- Lim Steve
- Lin Yen Ting
- Linas Benjamin P.
- Linkov Igor
- Liu Tie-Yan
- Lopez Velma K.
- Lu Guoqing
- Lucas Benjamin
- Lushtak Samuel M.
- Ma Yian
- Mallela Abhishek
- Manetti Elisa
- Mann Ethan
- Marathe Madhav
- Marshall Maximilian
- Martin Emily T.
- Mayo Michael L.
- Mayorga Maria E.
- McAndrew Thomas
- McCauley Ella
- McConnell Steve
- McDonald Daniel
- Meakin Sophie R.
- Mehrotra Prakhar
- Mele Jessica
- Meredith Hannah R.
- Merugu Srujana
- Meyers Lauren Ancel
- Michaud Isaac
- Miller Ely
- Milliken John
- Mody Vidhi
- Mody Vrushti
- Mohler George
- Moloney Michael
- Moore Sean
- Morgan James
- Morley Christopher P.
- Mu Kunpeng
- Mueller Peter
- Mullany Luke C.
- Murray Chris
- Myers Robert L.
- Mühlemann Anja
- Nagraj V. P.
- Namigai Kristen
- Narasimhan Balasubramanian
- Ndong David Nze
- Neumann Jacob
- Ngo Thoai
- Nickel Maximilian
- Niemi Jarad
- Nirgudkar Ninad
- Nixon Kristen
- Nouvellet Pierre
- Obozinski Guillaume
- Oidtman Rachel
- Oruc Buse Eylul
- Osthus Dave
- Ozcan Gokce
- O’Dea Eamon B.
- Pagano Robert
- Panaggio Mark J.
- Parno Matthew D.
- Pasumarty Sujitha
- Peddireddy Akhil Sai
- Penna Nicolas D.
- Perakis Georgia
- Perez-Saez Javier
- Perkins Alex
- Pfeiffer Ruth
- Pfister Tomas
- Pigott David
- Piontti Ana Pastore y
- Piriya Matthew
- Piwonka Noah
- Politsch Collin
- Popken Max
- Porebski Przemyslaw
- Posner Richard
- Prakash B. Aditya
- Qian Cheng
- Rainwater-Lovett Kaitlin
- Rajanala Samyak
- Raval Alpan
- Ravi Matt
- Ray Evan L.
- Reich Nicholas G.
- Reich Nicholas G.
- Reiner Robert C.
- Riley Pete
- Riley Steven
- Rivadeneira Alvaro J. Castro
- Rodríguez Alexander
- Romberg Justin
- Rosenstrom Erik T.
- Rowland Michael A.
- Rumack Aaron
- Sagun Levent
- Salekin Asif
- Sarker Arnab
- Schrader Chris
- Schwarz Tom
- Scott James G.
- Sen Pei
- Serban Nicoleta
- Shah Apurv
- Shah Devavrat
- Shah Sam
- Shakhnovich Elizabeth
- Shaman Jeffrey
- Sharma Rakshith
- Sheldon Daniel
- Sherratt Katharine
- Shi Yunfeng
- Shin Lauren
- Shingi Siddhant
- Shrivastav Monika
- Siegel Daniel
- Simon Noah
- Singhvi Divya
- Sinha Deeksha
- Sinha Rajarishi
- Slayton Rachel B.
- Smith Claire P.
- Soni Saksham
- Soohoo Connor
- Spaeder Jeffrey
- Spantidakis Ioannis
- Spatz Ryan
- Srivastava Ajitesh
- Stage Steven A.
- Stark Ariane
- Stiefeling Chris
- Suchoski Bradley T.
- Sumner Timothy
- Sun Jimeng
- Sun Tao
- Sundar Saketh
- Swann Julie L.
- Tabassum Anika
- Tallaksen Katharine
- Tec Mauricio
- Thanou Dorina
- Thayaparan Leann
- Tibshirani Rob
- Tibshirani Ryan J.
- Tirumala Kushal
- Tiwari Avtansh
- Tomar Vishal
- Tran Quoc
- Truelove Shaun A.
- Trump Benjamin D.
- Tsai Thomas
- Tseng Albert
- Tsiourvas Asterios
- Turner Stephen D.
- Turtle James
- US COVID-19 Forecast Hub Consortium
- Vahedi Behzad
- Van Bussel Frank
- van de Walle Axel
- Varadarajan Vignesh
- Venkatramanan Srinivasan
- Ventura Valerie
- Vespignani Alessandro
- Vytheeswaran Jagath
- Walker Jo W.
- Walraven Robert
- Wang Christopher
- Wang Dongdong
- Wang Dongliang
- Wang Guannan
- Wang Lijing
- Wang Lily
- Wang Lingxiao
- Wang Liqiang
- Wang Qinxia
- Wang Yijin
- Wang Yu-Xiang
- Wang Yuanjia
- Wang Yueying
- Wang Zhongying
- Wasserman Larry
- Wattanchit Nutcha
- Weisberg Shane
- White Jerome
- Wilde Joshua
- Wilkinson Barrie
- Wills Josh
- Wilson Austin
- Wilson Daniel
- Wilson Shelby
- Wolffram Daniel
- Wolfinger Russ
- Wong Alexander
- Woody Spencer
- Wu Dongxia
- Xiao Cao
- Xiao Jade
- Xie Jiajia
- Xie Shanghong
- Xie Xing
- Xiong Xinyue
- Xu Pan
- Xu Tianjian
- Yamana Teresa K.
- Yan Xifeng
- Yeluri Akshay
- Yeung Dit-Yan
- Yoder Nate
- Yogurtcu Osman N.
- Yoon Jinsung
- You Jialu
- Yu Rose
- Yu Shan
- Yurk Dominic
- Zeng Donglin
- Zhang Leyou
- Zhang Michael
- Zhang Shun
- Zhang Shunpu
- Zhang Weitong
- Zhang-James Yanli
- Zhao Yanting
- Zheng Andrew
- Zheng Shun
- Zhou Mingyuan
- Zimmerman Peter
- Zlokapa Alexander
- Zoraghein Hamidreza
- Zorn Martha W.
- Zou Difan
- Zou Zihang
- Publication venue
- Nature Research
- Publication date
- 17/08/2022
- Field of study
Academic researchers, government agencies, industry groups, and individuals have produced forecasts at an unprecedented scale during the COVID-19 pandemic. To leverage these forecasts, the United States Centers for Disease Control and Prevention (CDC) partnered with an academic research lab at the University of Massachusetts Amherst to create the US COVID-19 Forecast Hub. Launched in April 2020, the Forecast Hub is a dataset with point and probabilistic forecasts of incident cases, incident hospitalizations, incident deaths, and cumulative deaths due to COVID-19 at county, state, and national, levels in the United States. Included forecasts represent a variety of modeling approaches, data sources, and assumptions regarding the spread of COVID-19. The goal of this dataset is to establish a standardized and comparable set of short-term forecasts from modeling teams. These data can be used to develop ensemble models, communicate forecasts to the public, create visualizations, compare models, and inform policies regarding COVID-19 mitigation. These open-source data are available via download from GitHub, through an online API, and through R packages
Finishing the euchromatic sequence of the human genome
- Author
- . Haifeng
- . Magner
- . Yin
- Abbott Scott
- Abbott-Ozersky Amanda
- Abdellah Zahra
- Abouelleil Amr
- Abrajano Anne
- Adachi Tamami
- Adam Catherine
- Adams Charles Q.
- Adamson Aaron
- Adekoya Emmanuel
- Adio-Oduola Babajide
- Aerts Andrea
- Aggarwal Arun
- Ahmadi Alireza
- Ahmed Shahana
- Aimable Matthew
- Ainscough Rachael
- Ait-Zahra Mostafa
- Aizu Tomoyuki
- Alcivare Dana
- Alegria Michelle
- Ali Alla
- Ali Johar
- Allegria-hartmann Michelle
- Alleman Jennifer
- Allen Carlana C.
- Allen Heather
- Allen Nicole R.
- Allen Susan
- Allen Thaddeus
- Almeida Jeff
- Almond Claire
- Alsbrooks Stephen L.
- Altherr Michael R.
- Amaratunge Harshinie C.
- Ambler Andrew
- Ambrose Karen
- Ambrose Kerrie
- Amemiya Chris
- Amico-Keller Gina
- Amin Amita G.
- Anderson Mechele
- Anderson Scott
- Anderson Scott
- Andora Janice
- Andredesz Carol
- Andrew Robert
- Andrews Dan
- Andrews Daniel
- Andrews Neil
- Andrews Stephanie
- Andriese Tim
- Anthouard Véronique
- Antonarakis Stylianos E.
- Anyalebechi Vivian
- Aoki Norie
- Apostolou Sinoula
- Apweiler Eva
- Arachchi Harindra
- Arai Rie
- Arbery Hazel
- Arcaina Marlon
- Arcaina Terisita
- Archer Beth
- Arellano Andre
- Arellano-Jones Perry
- Armbruster Jeff
- Armstrong Jon
- Arredondo Dilrukshi P.
- Arredondo Heather Hope
- Artiguenave François
- Asakawa Shuichi
- Asakawa Teruyo
- Ash Gareth
- Ashcroft Kevin
- Ashurst Jennifer
- Ashwell Robert
- Ashworth Linda K.
- Aslanidis Cara
- Asomugha Chinwe O.
- Asuncion Lawreen
- Atkin Deborah
- Atkinson Andrea
- Atkinson Barry
- Attix Cristina
- Attwood John
- Aubin Keith
- Auger Katherine
- Austin Shannon Michelle
- Avila Aaron
- Avis Terry
- Ayele Mulu
- Babayan Primo
- Babbage Anne
- Babbage Sarah
- Bach Phil
- Bachatsang Pasang
- Bacon Joanne
- Badri Hummy
- Baertsch Robert
- Bagguley Claire
- Bailey Jonathan
- Bajorek Eva
- Baker Andrew
- Baker Dan
- Baker M.
- Baker Richard
- Bakis Michele
- Baldwin Jennifer
- Banda Michael
- Banerjee Ruby
- Bao Jingyue
- Bao Qiyu
- Bao Weidong
- Bao Weidong
- Baptiste Pertrice
- Barbaria Joseph A.
- Barbe Valérie
- Bardill Simon
- Barker Daniel
- Barker Darren
- Barker Gary
- Barlow Karen
- Baron Laurent
- Barrett Anika
- Bartlett Rebecca
- Basham Victoria
- Bashman David
- Basu Suba
- Bateman Alex
- Bates Karen
- Battles John
- Batzer Mark
- Baumgart Cornelia
- Baumohl Jason
- Baynes Caroline
- Bayul Tashi
- Beall Keith
- Beard Lisa
- Beard Susan
- Beare David
- Beasley Alastair
- Beasley Helen
- Beasley Oliver
- Beaucham Leslie
- Beaudet Arthur
- Beck Alfred
- Beck Stephen
- Becker Michael
- Bell Emma
- Bell George I.
- Bellard Terell M.
- Bellerby Damian
- Bellerby Tristram
- Belter Edward A., Jr.
- Bemrose Richard
- Benard Michael Anthony
- BenKahla Alia
- Benke J
- Benner William
- Bennett James
- Bensasson Douda
- Bentley Andrew
- Bentley Dan
- Bentley David
- Berardinis Véronique de
- Bercovitz John
- Berghoff Amy
- Bergmann Anne
- Berkowicz Nicolas
- Berks Mary
- Berks Michael
- Bethel Graeme
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- Lovell Jamie
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- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
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- MacLean Christine
- Madabhushi Ramki
- Madu Renita C.
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- Wylie Kris
- Wyman Dudley
- Wyman Stacia
- Xi Yan
- Xi Yingying
- Xie Fei
- Xie Gary
- Xie Jane
- Xiong Hui
- Xiong Yuqing
- Xu Alex
- Xu Jing
- Xu Jing
- Xu Ruqin
- Xu Shuhua
- Xu Wei
- Xu Xinlai
- Xu Yan
- Xu Yuning
- Xu Zhihong
- Xu Zuyuan
- Xuan Yali
- Xuan Zhenyu
- Xue Rui
- Yada Tetsushi
- Yadav Shailendra
- Yakub Syed
- Yamamoto Lynn
- Yamamoto Noriko
- Yamamoto Yuko
- Yamashita Yasue
- Yamazaki Satoru
- Yang Hao
- Yang Huanming
- Yang Huanming
- Yang Joan
- Yang Shiaw-Pyng
- Yang Shudong
- Yang Xiaonan
- Yang Xiaonan
- Yang Xiaoping
- Yang Yongkui
- Yano Candance
- Yao Zhijian
- Yao Zhijian
- Yaspo Marie-Laure
- Ye Chen
- Yeager Shane
- Yeh Mimi
- Yen Jennifer
- Yeshitela Rahel Retta
- Yoakum Martin
- Yokobata Kathy
- Yokoyama Jennifer
- Yonezawa Miho
- Yoon Lillienne
- Yoon Vivienne
- Yoshida Satoru
- You Bo
- Young Geneva
- Young Louise
- Young Shelia
- Younger Ruth
- Yu Bing
- Yu Charles
- Yu Fuli
- Yu Jun
- Yu Jun
- Yu Jun
- Yuan Kaiwen
- Yuan Ye
- Yuan Yida
- Yue Shujie
- Yumae Brian
- Yun Rui
- Zainoun Joanne
- Zembeck Lisa
- Zeng Yixin
- Zhai Dong
- Zhan Guoping
- Zhang Bo
- Zhang Caimin
- Zhang Fengmei
- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission
- Author
- Aanensen David M.
- Abell Chris
- Abudahab Khalil
- Acheson Erwan
- Adams Alexander
- Adams Helen
- Afifi Safiah
- Aggarwal Dinesh
- Aggarwal Dinesh
- Ahmad Shazaad S. Y.
- Ahmadi-Assalemi Gabriela
- Aigrain Louise
- Alam Mohammad T.
- Alcolea-Medina Adela
- Alderton Alex
- Alikhan Nabil-Fareed
- Allara Elias
- Amato Roberto
- Andersson Monique
- Angelis Daniela De
- Angelis Daniela De
- Angyal Adrienn
- Aranday-Cortes Elihu
- Ariani Cristina V.
- Asad Hibo
- Asamaphan Patawee
- Ash Amy
- Ashcroft Fiona
- Atkinson Laura
- Attwood Stephen W.
- Auckland Cressida
- Awan Ali R.
- Aydin Alp
- Baker David J.
- Baker Paul
- Balcazar Carlos E.
- Ball Jonathan
- Barrett Jeff
- Barton Edward
- Bashton Matthew
- Bassett Andrew R.
- Batra Rahul
- Baxter Laura
- Bayzid Nadua
- Beale Mathew A.
- Beaver Charlotte
- Beckett Angela H.
- Bedford Luke
- Beer Robert
- Beggs Andrew
- Bellis Katherine L.
- Berry Lisa
- Berry Louise
- Berry Sarah
- Best Angus
- Betancor Gilberto
- Betteridge Emma
- Bewshea Claire M.
- Bibby David
- Bicknell Kelly
- Birchley Alec
- Bird Paul
- Bishop Chloe
- Blacow Rachel
- Blakey Victoria
- Blane Beth
- Bolt Frances
- Bonfield James
- Bonner Stephen
- Bonsall David
- Boswell Tim
- Bosworth Andrew
- Bourgeois Yann
- Boyd Olivia
- BoYes John
- Bradley Amanda
- Bradley Declan T.
- Bradshaw Daniel
- Braithwaite Vickie
- Breen Cassie
- Bresner Catherine
- Breuer Judith
- Bridgewater Hannah E.
- Brierley Craig
- Bronner Iraad F.
- Brooks Ellena
- Broos Alice
- Brown Christopher
- Brown Christopher A.
- Brown Julianne R.
- Brown Nicholas M.
- Brown Paul E.
- Brown Rebecca
- Bucca Giselda
- Buck David
- Bull Matthew
- Burton-Fanning Shirelle
- Campbell Sharon
- Carabelli Alessandro M.
- Carden Holli
- Carlile Matthew
- Carmichael Stephen N.
- Casey Anna
- Caspersz Michelle
- Ceaser Matt
- Cerda Alberto C.
- Chalker Vicki
- Chand Meera
- Chapman Michael H. S.
- Chapman Michael R.
- Chappell Joseph G.
- Charalampous Themoula
- Chatterton Wendy
- Chaudhry Afzal
- Chaudhry Yasmin
- Chauhan Anoop J.
- Cheng Jeffrey K. J.
- Churcher Carol M.
- Clark Gemma
- Clark Roger
- Clarke Rebecca
- Cogger Benjamin J.
- Coll Francesc
- Collins Jennifer
- Connor David
- Connor Thomas R.
- Constantinidou Chrystala
- Cook Kate
- Coombes Jason
- Corden Sally
- Cormie Claire
- Cortes Nick
- Cotic Marius
- Cottrell Simon
- Coupland Lindsay
- Cowell Angela
- Cox Alison
- Craine Noel
- Crawford Liam
- Cronin Michelle
- Crook Derrick
- Crowcroft Jon
- Cumley Nicola
- Curran Martin D.
- Curran Tanya
- da Silva Filipe Ana
- Dabrera Gavin
- Dadrah Ashok
- Dahal Aastha
- Danaei Darius
- Danesh John
- Darby Alistair C.
- Davidson Rose K.
- Davies Alisha
- Davies Richard
- Davies Robert
- Davis Thomas
- de Cesare Mariateresa
- de Oliveira Martins Leonardo
- de Silva Thushan I.
- Debebe Johnny
- Dent Hannah
- Dervisevic Samir
- Dewar Rebecca
- Dhada Maharshi
- Dias Joana
- Dorman Matthew J.
- Dougan Gordon
- Douthwaite Julie
- Downing Fatima
- Drury Eleanor
- du Plessis Louis
- du Plessis Louis
- Duckworth Nichola
- Durham Jillian
- Dyer Rory
- Eccles Richard
- Edgeworth Jonathan
- Edwards Sue
- Eldirdiri Sahar
- Ellaby Nicholas
- Ellard Sian
- Elliott Scott
- Eltringham Gary
- Emanuela P.
- Enright Jessica
- Ensell Leah
- Essex Sarah
- Evans Cariad
- Evans Johnathan M.
- Eyre David
- Fairley Derek J.
- Fallon Karlie
- Farbos Audrey
- Farr Ben W.
- Fatseas Tania
- Faulkner Kathryn
- Fearn Christopher
- Feather Tom
- Feltwell Theresa
- Fenton Melisa L.
- Ferris Mark
- Fieldman Thomas
- Fina Laia
- Fisher Chloe L.
- Flaviani Flavia
- Fleming Vicki M.
- Forrest Sally
- Foulser Luke
- Francois Sarah
- Fraser Christophe
- Freeling Anthony
- Freeman Timothy M.
- Frost Lucy R.
- Fuller Stewart
- Fuller William
- Galai Katerina
- Gallagher Eileen
- Gallagher Michael D.
- Gallis Marta
- Gaskin Amy
- Gatica-Wilcox Bree
- Geidelberg Lily
- Gemmell Matthew
- Georgana Iliana
- George Ryan P.
- Georgiou Christine
- Gibbs Karen
- Gifford Laura
- Gilbert Lauren
- Gill Harmeet K.
- Girgis Sophia T.
- Glaysher Sharon
- Glew Rob
- Glover Michael
- Golubchik Tanya
- Goncalves Sonia
- Goodall Robin
- Goodfellow Ian
- Goodfellow Ian G.
- Goodwin Scott
- Goudarzi Salman
- Gourtovaia Marina
- Graham Clive
- Graham Lee
- Grammatopoulos Dimitris
- Gransden Lucie
- Greatorex Jane
- Green Angie
- Green Luke R.
- Greenaway Jane
- Gregory Richard
- Groves Danielle C.
- Groves Natalie
- Guest Martyn
- Gulliver Huw
- Gunson Rory N.
- Gupta Ravi K.
- Gutierrez Bernardo
- Hadjirin Nazreen F.
- Haldenby Sam T.
- Hale Antony D.
- Hall Grant
- Halstead Fenella
- Hamilton William L.
- Hamilton William L.
- Hamilton William L.
- Hancock Dawn
- Hannan Sophie
- Haque Tanzina
- Harper Katherine L.
- Harris Kathryn A.
- Harrison Ewan M.
- Harrison Ian
- Harrison James W.
- Hart Jennifer
- Hartley John A.
- Hartman Hassan
- Hassan-Ibrahim Mohammed O.
- Heaney Judith
- Helmer Thomas
- Henderson Robert
- Hesketh Andrew R.
- Heyburn David
- Higginson Ellen E.
- Hilborne Sarah
- Hill Verity
- Hilvers Ember
- Hiscox Julian A.
- Hoensch Steve
- Hogsden Wendy
- Holden Matthew T. G.
- Holgate Jon
- Hollamby Victoria
- Holmes Alison
- Holmes Christopher
- Holmes Nadine
- Hopes Richard
- Hosaja Aleksandra
- Hosmillo Myra
- Hosmillo Myra
- Howe Robin
- Howes Rob
- Howson-Wells Hannah C.
- Hubb Jonathan
- Hughes Gareth J.
- Hughes Joseph
- Hughes Margaret
- Hughes Robert
- Hunt Martin
- Hutchings Stephanie
- Illingworth Chris
- Illingworth Chris J.
- Impey Robert
- Irish-Tavares Dianne
- Iturriza-Gomara Miren
- Izuagbe Rhys
- Jackson Chris
- Jackson David K.
- Jackson Kathryn A.
- Jahun Aminu
- Jahun Aminu S.
- James Keith
- James Laura
- Jamrozy Dorota
- Jannoo Riaz
- Jeffries Aaron R.
- Jeremiah Sarah
- Jesudason Natasha G.
- John Michaela
- Johnson Dean
- Johnson Kate
- Johnson Natasha
- Johnson Rob
- Johnston Ian
- Jones Carl
- Jones Christopher R.
- Jones Daniel R.
- Jones Hannah
- Jones Katie
- Jones Rachel
- Jones Sophie
- Jordan Sinead
- Jorgensen David
- Joseph Amelia
- Justice Anita
- Kahkeshi Mahin Bagheri
- Kane Leanne
- Karamani Angeliki
- Kay Gemma L.
- Kay Sally
- Keatley Jon-Paul
- Keeley Alexander J.
- Keen Martin
- Kenyon Anita
- Kermack Leanne M.
- Khakh Manjinder
- Kidd Stephen
- Kitchen Christine
- Knapton James
- Knight Bridget A.
- Koshy Cherian
- Kraemer Moritz U. G.
- Kristiansen Mark
- Kuenzi Fred
- Kumziene-SummerhaYes Sara
- Kwiatkowski Dominic
- Lackenby Angie
- Lacy Elen De
- Lambson Oliver
- Langford Cordelia F.
- Lawniczak Mara
- Le-Viet Thanh
- Ledesma Juan
- Lee David
- Lee Jack C. D.
- Leek Danielle
- Lehner Paul
- Lensing Stefanie V.
- Leonard Steven
- Leong Clare
- Leslie Ian
- Letchford Laura
- Levene Nick
- Levett Lisa J.
- Lewis Kevin
- Li Kathy K.
- Liddell Kathleen
- Liddle Jennifier
- Liggett Steven
- Lindsey Benjamin B.
- Lister Michelle M.
- Livett Rich
- Lloyd Allyson
- Lo Stephanie
- Loman Nicholas J.
- Loose Matthew W.
- Louka Stavroula F.
- Loveson Katie F.
- Lowe Hannah
- Lowe Helen L.
- Lucaci Anita O.
- Ludden Catherine
- Ludden Catherine
- Lynch Jessica
- Lyons Ronan A.
- Macfarlane-Smith Louissa R.
- Machin Nicholas W.
- MacIntyre-Cockett George
- Maclean Alasdair
- Mactavous Lenette
- Madona Pinglawathee
- Maes Mailis
- Mahanama Adhyana I. K.
- Mahungu Tabitha W.
- Mair Daniel
- Maksimovic Joshua
- Makunin Alex
- Malone Cassandra S.
- Manesis Nikos
- Manley Robin
- Manso Carmen
- Marchbank Angela
- Marchetti Filippo
- Margolis Ben
- Martincorena Inigo
- Masoli Jane A. H.
- Mason Jenifer
- Mather Alison E.
- Matheson Nicholas
- Matheson Nicholas J.
- Mathieson Nick
- Matthews Steve
- Maxwell Patrick
- Maxwell Patrick H.
- Mayhew Megan
- Mbisa Tamyo
- McCann Clare
- McCarthy Shane
- McCluggage Kathryn
- McClure Patrick C.
- McFarlane Duncan
- McGuigan Samantha
- McHugh Martin P.
- McKenna James P.
- McKerr Caoimhe
- McManus Georgina M.
- McMurray Claire
- McNally Alan
- McNulty Claire
- Meader Emma J.
- Meadows Lizzie
- Megram Oliver
- Menegazzo Mirko
- Merrick Ian
- Merrill Tammy V.
- Metaxaki Marina
- Miah Shahjahan
- Michell Stephen L.
- Michelsen Michelle L.
- Mills John
- Mirza Jeremy
- Moles-Garcia Emma
- Moll Robin J.
- Mollett Guy
- Molnar Zoltan
- Monaghan Lynn
- Mookerjee Siddharth
- Moore Catherine
- Moore Christopher
- Moore Jonathan
- Moore Nathan
- Morgan Mari
- Morgan Sally
- Morgan Sian
- Mori Matilde
- Moses Samuel
- Mozdzen Barbara
- Muir Peter
- Mungovan Diane
- Munn Robert
- Murphy Edna
- Myers Richard
- Nascimento Fabricia F.
- Nebbia Gaia
- Neely Andy
- Nelson Andrew
- Nelson Charlotte
- Nelson Rachel
- Nicholls Sam
- Nichols Jenna
- Nickbakhsh Seema
- Niebel Marc O.
- Nikitina Katya
- Nomikou Kyriaki
- Nsonwu Olisaeloka
- Nunez Rocio T. Martinez
- Oliver Karen
- Orton Alexandra
- Orton Richard J.
- Osman Husam
- Ott Sascha
- O’Brien Sarah
- O’Grady Justin
- O’Toole Elaine
- O’Toole Áine
- Pacchiarini Nicole
- Packer Simon
- Padgett Debra
- Page Andrew J.
- Palmer Sophie
- Palmer Steve
- Pandey Sarojini
- Park Naomi R.
- Parker Matthew D.
- Parlikad Ajith
- Parmar Surendra
- Parsons Paul J.
- Partridge David G.
- Patel Amita
- Patel Minal
- Patel Vineet
- Paterson Steve
- Paul Hannah
- Payne Brendan AI.
- Peacock Sharon J.
- Peacock Sharon J.
- Pearson Clare
- Percival Benita
- Perry Malorie
- Peto Timothy
- Pinckert Malte
- Pinckert Malte L.
- Platt Steven
- Plimmer Amy
- Poplawski Radoslaw
- Poppitt Steve
- Prestwood Liam
- Price Anna
- Price James
- Prieto Jacqui A.
- Puethe Christoph
- Pusok Monika
- Pybus Oliver G.
- Pymont Hannah M.
- Quail Michael A.
- Quick Joshua
- Quinnell Natalie
- Radecki Asako
- Raghwani Jayna
- Ragonnet-Cronin Manon
- Rainbow Lucille
- Rajan Diana
- Rajatileka Shavanthi
- Rambaut Andrew
- Ramsay Mary
- Randell Paul A.
- Rankin Jennifer
- Ratcliffe Liz
- Raub Gabor
- Raviprakash Veena
- Raza Mohammad
- Redshaw Nicholas M.
- Rees Steve
- Rey Sara
- Reynolds Nicola
- Richter Alex
- Ridgman Tom
- Robertson David L.
- Robinson Esther
- Robinson Trevor I.
- Robson Samuel C.
- Rooke Stefan
- Rowan Aileen
- Rowe Will
- Roy Sunando
- Rudder Steven
- Ruis Chris
- Rushton Steven
- Russell Matthew
- Saeed Kordo
- Saluja Tranprit
- Samaraweera Buddhini
- Sambles Christine M.
- Samtani Vijay
- Samworth Richard
- Sang Fei
- Sato Aris
- Scarlett Garry P.
- Schaefer Ulf
- Scott Carol
- Scott Garren
- Searle Paul
- Shaaban Sharif
- Shah Divya
- Shah Rajiv N.
- Shankar Giri
- Shaw Ashley
- Sheldrake Zara
- Shepherd James G.
- Sheridan Linda
- Sheriff Nicola
- Shirley Lesley
- Signell Adrian W.
- Sillitoe John
- Silveira Siona
- Simpson David A.
- Sing Robert
- Singer Joshua B.
- Sivaprakasam Venkat
- Siveroni Igor
- Sloan Tim J.
- Sluga Graciela
- Smith Colin P.
- Smith Darren
- Smith Kim S.
- Smith Louise
- Smith Nikki
- Smith Wendy
- Smollett Katherine L.
- Snell Luke B.
- Southgate Joel
- Spellman Karla
- Sridhar Sushmita
- Stanley Rachael
- Stanton Thomas D.
- Starinskij Igor
- Stark Richard
- Stockton Joanne
- Stonehouse Susanne
- Storey Nathaniel
- Studholme David J.
- Swindells Emma
- Symmonds Amanda
- Taha Yusri
- Tang Julian
- Taylor Ben E. W.
- Taylor Graham P.
- Taylor Peter
- Taylor Sarah
- Taylor-Joyce Grace
- Temperton Ben
- Templeton Kate E.
- The Cambridge Covid-19 testing Centre
- The COVID-19 Genomics UK (COG-UK) Consortium
- Thompson Thomas
- Thomson Emma C.
- Thornton Alicia
- Thurston Scott A. J.
- Todd John A.
- Tolhurst Jonathan
- Tong Lily
- Tonkin-Hill Gerry
- Torok M. Estee
- Tovar-Corona Jaime M.
- Trebes Amy
- Trotter Alexander J.
- Tsoleridis Theocharis
- Tucker Rachel M.
- Turtle Lance
- Twohig Katherine A.
- Tynan Jo
- Underwood Anthony P.
- University of Cambridge Asymptomatic COVID-19 Screening Programm
- Unnikrishnan Meera
- Valletta Sally
- Vamos Edith E.
- Vasylyeva Tetyana I.
- Vattipally Sreenu
- Vernet Gabrielle
- Vignoles Anna
- Vinnell Martin
- Vipond Ian B.
- Volz Erik M.
- Waddell Ian
- Walsh Sarah
- Wang Dennis
- Wantoch Michelle
- Warne Ben
- Warwick-Dugdale Joanna
- Wastenge Elizabeth
- Watkins Emmeline
- Watkins Joanne
- Watts Joanne
- Waugh Sheila
- Weale Gillian
- Webster Hermione J.
- Weekes Michael P.
- Weldon Danni
- Westhorpe Adam P.
- White Phil
- Whitehead Mark
- Whiteley Max
- Whitwham Andrew
- Wierzbicki Claudia
- Williams Charlotte A.
- Williams Chris
- Williams David
- Williams Lesley-Anne
- Williams Rachel J.
- Williams Rebecca
- Williams Thomas
- Williamson Kathleen A.
- Williman Jack
- Willingham Iona
- Wills Mark
- Wilson Harry D.
- Wilson Karl
- Wilson Rebekah E.
- Wilson-Davies Eleri
- Winster Jennifer
- Wise Emma
- Witele Eric
- Workman Chris
- Workman Trudy
- Wright Elizabeth
- Wright Elizabeth
- Wright Giles
- Wright Jo
- Wright Victoria
- Wyatt Tim
- Wyles Matthew
- Wyllie Sarah
- Xu-McCrae Li
- Yeats Corin A.
- Yew Wen Chyin
- Young Greg
- Young Jamie
- Zamudio Marina Escalera
- Zarebski Alex E.
- Zhang Peijun
- Publication venue
- Nature Communications
- Publication date
- 08/02/2022
- Field of study
AbstractUnderstanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the university or the community. Our study highlights key determinants of SARS-CoV-2 transmission and effective interventions in a higher education setting that will inform public health policy during pandemics.</jats:p
Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Nuclear import of protein kinase D1 (PKD1) is an important event in the transcriptional regulation of cardiac gene reprogramming leading to the hypertrophic growth response, however, little is known about the molecular events that govern this event. We have identified a novel complex between PKD1 and a heat shock protein (Hsp), Hsp20, which has been implicated as cardioprotective. This study aims to characterize the role of the complex in PKD1-mediated myocardial regulatory mechanisms that depend on PKD1 nuclear translocation
Effect of CYP1A inhibition on the biotransformation of benzo[a]pyrene in two populations of Fundulus heteroclitus with different exposure histories
- Publication venue
- 'Elsevier BV'
- Publication date
- Field of study