22 research outputs found
Solar UV irradiance in a changing climate: Trends in europe and the significance of spectral monitoring in Italy
Review of the existing bibliography shows that the direction and magnitude of the long-term trends of UV irradiance, and their main drivers, vary significantly throughout Europe. Analysis of total ozone and spectral UV data recorded at four European stations during 1996–2017 reveals that long-term changes in UV are mainly driven by changes in aerosols, cloudiness, and surface albedo, while changes in total ozone play a less significant role. The variability of UV irradiance is large throughout Italy due to the complex topography and large latitudinal extension of the country. Analysis of the spectral UV records of the urban site of Rome, and the alpine site of Aosta reveals that differences between the two sites follow the annual cycle of the differences in cloudiness and surface albedo. Comparisons between the noon UV index measured at the ground at the same stations and the corresponding estimates from the Deutscher Wetterdienst (DWD) forecast model and the ozone monitoring instrument (OMI)/Aura observations reveal differences of up to 6 units between individual measurements, which are likely due to the different spatial resolution of the different datasets, and average differences of 0.5–1 unit, possibly related to the use of climatological surface albedo and aerosol optical properties in the retrieval algorithms
Excess cardiovascular mortality associated with cold spells in the Czech Republic
<p>Abstract</p> <p>Background</p> <p>The association between cardiovascular mortality and winter cold spells was evaluated in the population of the Czech Republic over 21-yr period 1986–2006. No comprehensive study on cold-related mortality in central Europe has been carried out despite the fact that cold air invasions are more frequent and severe in this region than in western and southern Europe.</p> <p>Methods</p> <p>Cold spells were defined as periods of days on which air temperature does not exceed -3.5°C. Days on which mortality was affected by epidemics of influenza/acute respiratory infections were identified and omitted from the analysis. Excess cardiovascular mortality was determined after the long-term changes and the seasonal cycle in mortality had been removed. Excess mortality during and after cold spells was examined in individual age groups and genders.</p> <p>Results</p> <p>Cold spells were associated with positive mean excess cardiovascular mortality in all age groups (25–59, 60–69, 70–79 and 80+ years) and in both men and women. The relative mortality effects were most pronounced and most direct in middle-aged men (25–59 years), which contrasts with majority of studies on cold-related mortality in other regions. The estimated excess mortality during the severe cold spells in January 1987 (+274 cardiovascular deaths) is comparable to that attributed to the most severe heat wave in this region in 1994.</p> <p>Conclusion</p> <p>The results show that cold stress has a considerable impact on mortality in central Europe, representing a public health threat of an importance similar to heat waves. The elevated mortality risks in men aged 25–59 years may be related to occupational exposure of large numbers of men working outdoors in winter. Early warnings and preventive measures based on weather forecast and targeted on the susceptible parts of the population may help mitigate the effects of cold spells and save lives.</p
Apparent Temperature and Air Pollution vs. Elderly Population Mortality in Metro Vancouver
Background: Meteorological conditions and air pollution in urban environments have been associated with general population and elderly mortality, showing seasonal variation. Objectives: This study is designed to evaluate the relationship between apparent temperature (AT) and air pollution (PM2.5) vs. mortality in elderly population of Metro Vancouver. Methods: Statistical analyses are performed on moving sum daily mortality rates vs. moving average AT and PM 2.5 in 1-, 2-, 3-, 5-, and 7-day models for all seasons, warm temperatures above 15uC, and cold temperatures below 10uC. Results: Approximately 37 % of the variation in all-season mortality from circulatory and respiratory causes can be explained by the variation in 7-day moving average apparent temperature (r 2 = 0.37, p,0.001). Although the analytical results from air pollution models show increasingly better prediction ability of longer time-intervals (r 2 = 0.012, p,0.001 in a 7-day model), a very weak negative association between elderly mortality and air pollution is observed. Conclusions: Apparent temperature is associated with mortality from respiratory and circulatory causes in elderly population of Metro Vancouver. In a changing climate, one may anticipate to observe potential health impacts from the projected high- and particularly from the low-temperature extremes
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
BACKGROUND:
Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes.
METHODS:
We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization.
RESULTS:
During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events.
CONCLUSIONS:
Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)
Nuove tecniche per la valutazione dell'irradianza ultravioletta solare e del contenuto colonnare di ozono: è ancora necessaria la misura da terra?
La recente comparsa di episodi di assottigliamento dello strato di ozono (“buco dell'ozono”) al polo nord, in aggiunta al fenomeno analogo osservato da maggior tempo al polo sud, e la comprensione dei legami che sussistono tra cambiamento climatico, composizione atmosferica e radiazione in arrivo alla superficie del pianeta, confermano l'importanza scientifica, nonché la rilevanza pratica, del monitoraggio della radiazione ultravioletta (UV) solare e dell'ozono colonnare. La strumentazione da terra, finora considerata il riferimento insuperato, ed il suo mantenimento richiedono necessariamente una elevata esperienza da parte dell’operatore, delicate politiche di taratura e investimenti regolari. Gli ultimi decenni, tuttavia, hanno visto progredire e diffondersi, in seno alla comunità scientifica, nuove tecniche di misura, basate ad esempio su radiometri satellitari, o di stima previsionale, a partire da modelli meteo e di trasporto radiativo. Tali dati sono facilmente reperibili in rete, spesso senza costi aggiuntivi. Da qui la domanda: vale ancora la pena investire nella strumentazione ground-based, in un momento di contrazione delle risorse? Quali sono i limiti tecnologici e intrinseci, e quali i vantaggi, delle fonti alternative di informazione
Arbeitsmigrantinnen in der Landwirtschaft. Erkenntnisse über einen transnational segmentierten Arbeitsmarkt in der EU während der Covid-Pandemie
Die prekäre Situation von osteuropäischen Arbeitsmigrant*innen in der westeuropäischen Landwirtschaftsproduktion ist bislang nicht ausreichend untersucht. In unserem Beitrag analysieren wir sie als Folge eines transnational segmentierten Arbeitsmarktes in der EU und beleuchten, inwiefern Maßnahmen in der Covid-19 Pandemie für seine Aufrechterhaltung eine Rolle spielten. Mechanismen zur Reproduktion der benachteiligten Position von transnational mobilen Arbeitsmigrant*innen können auf diese Weise untersucht werden.
Schlagworte: Transnational segmentierter Arbeitsmarkt, Arbeitsmigrant*innen, EU, Covid-19-Pandemi