Implications of Implementing HDTV Over Digital Subscriber Line Networks

This thesis addresses the different challenges a telecommunications company would face when trying to implement an HDTV video service over a Digital Subscriber Line (DSL) connection. Each challenge is discussed in detail and a technology, protocol, or method is suggested to overcome that particular challenge. One of the biggest challenges is creating a network architecture that can provide enough bandwidth to support video over a network that was originally designed for voice traffic. The majority of the network connections to a customer premises in a telephony network consists of a copper pair. This type of connection is not optimal for high bandwidth services. This limitation can be overcome using Gigabit Ethernet (GE) over fiber in the core part of the network and VDSL2 in the access part of the network. For the purposes of this document, the core portion of the network is considered to be an area equal to several counties or approximately 50 miles in radius. The core network starts at the primary central office (CO) and spreads out to central offices in suburbs and small towns. The primary central office is a central point in the telecom operator\u27s network. Large trunks are propagated from the primary central office to smaller central offices making up the core network. The access portion of the network is considered to be an area within a suburb or small town from the central office to a subscriber\u27s home. Appendix A, located on page 60, contains a network diagram illustrating the scope of each of the different portions of the network. Considerations must also be given for the internal network to the residence such as category 5 (Cat5) cable or higher grade and network equipment that can provide up to 30 Megabits per second (Mbps) connections or throughput. The equipment in the telecommunications network also plays a part in meeting the challenge of 30 Mbps bandwidth. GE switches should be used with single mode fiber optic cable in the core part of the network. Digital Subscriber Line Access Multiplexers (DSLAM) with the capability to filter Internet Group Management Protocol (IGMP) messages should be used in the access part of the network to facilitate bandwidth utilization. Placement of this equipment and how the data is aggregated is another issue to consider when implementing HDTV service. Another major challenge facing the implementation of HDTV over DSL networks is controlling quality of service (QoS) throughout the network. Class of Service (CoS) and Differentiated Services (DiffServ) is a method of QoS that would enable video packets to have a higher priority and less delay than other data packets. The consumer could have data, video, and voice traffic all over the same DSL connection. Data, video and voice packets would need to have a different priority in order to maintain appropriate QoS levels for each service. The use of advanced technology in video encoding will be essential to the success of the video service. MPEG-2, MPEG-4, and Windows Media 9 are just a few of the video encoding technologies that could be used to reduce the necessary bandwidth for HDTV. The advancement of this technology is essential to allow telecommunications providers to offer HDTV. Another challenge for the telecom operator concerns the security of the network and service after implementation. Theft of service will be another area that the telecomm operator will be forced to resolve. The cable operators currently face this issue and lose millions of dollars in revenue. Authentication, IP filtering and MAC address blocking are a few possible solutions to this problem

Evaluating the deep-sea coral Acanella from Hawaii as a paleoceanographic archive

Deep-sea corals have emerged as potential proxies of changing paleoceanographic properties. The utility of deep-sea corals for the purpose of interpreting paleoclimatic reconstructions is still in the discovery phase. However, long life spans, a relatively stable habitat, and unique growth geometry provide support to the growing body of research that has identified deep-sea corals as indicators of past climate and ocean properties. Two colonies of Acanella were collected from the permanent thermocline at depths between 414 and 437 m in the Makapuu Coral Bed, Oahu, HI in 1997 by submersible. Here I present results from a pilot study of the deep-sea coral Acanella to evaluate its use as a paleoceanographic archive. Commonly referred to as “bamboo coral” due to their alternating segments of calcite and gorgonin, Acanella was radiocarbon dated using samples from the protinaceous gorgonin knuckles. Scanning electron microscope (SEM) images, stable isotope data (δ18O and δ13C), and a radiocarbon study of this azooxanthellate, ahermatypic coral were used to conclude that the vicinity where Acanella was growing in Makapuu Coral Bed most likely experienced significant shifts in thermocline depth over the course of the coral’s lifespan. Samples were taken from the innermost and outermost growth bands of two Acanella thick sections (one from each colony studied here). These samples were corrected for a reservoir effect of 450 years and yielded an age of 270 +/- 35 years old for colony one and 22 +/- 35 for colony two. Colony one of Acanella may have recorded shifts in the thermocline near Hawaii as indicated by a 6º warming of ocean temperatures over 50 years. This warming trend was not observed in colony two, indicating that more information on growth geometry and deep-sea coral biology is needed in order to safely confirm that Acanella is consistently archiving paleoceanographic properties of the microhabitat in which the corals grow

Heritability of susceptibility to Salmonella enteritidis infection in fowls and test of the role of the chromosome carrying the NRAMP1 gene

373 thirteen-week-old chicks issued from a commercial cross and 312 chickens from the L2 line were intravenously inoculated with 106 Salmonella enteritidis and the numbers of Salmonella in the spleen, liver and genital organs were assessed 3 days later. Heritabilities of the number of Salmonella were estimated at 0.02 ± 0.04 and 0.05 ± 0.05 in the liver; at 0.29 ± 0.07 and 0.10 ± 0.06 in the spleen; and at 0.16 ± 0.05 and 0.11 ± 0.08 in the genital organs, in the first and second experiments, respectively. The difference between the two experiments could result from sampling variations and from differences in the genetic structure of the two populations possibly including both heterosis and additive effects as well as their interaction in the first experiment. Genetic correlations between the number of bacteria in the genital organs and liver (0.56 ± 0.58 and 0.76 ± 0.32 in the first and second experiments, respectively) and spleen (0.37 ± 0.24 and 0.79 ± 0.23) were positive. Moreover a significant within-sire effect of VIL1, a marker gene for NRAMP1, was observed in 117 progeny resulting from 25 informative matings. These results indicate that there are genetic differences in the resistance to visceral infection by S. enteritidis in these commercial egg-laying flocks, and suggest that these differences are at least partly due to genetic polymorphism in the NRAMP1 region

Hatred and harm: the influence of digital pimps and the miseducation of the hyper-masculine man

Master's Project (M.A.) University of Alaska Fairbanks, 2021The purpose of this research project is to measure the effects of a correlation between exposure to violent, hardcore sexually-explicit Internet materials, or SEIM (also known as pornography), and behaviors and attitudes that demean, degrade, subjugate, and abuse women and girls resulting in systemic gender inequality. Research is based on peer-reviewed journal articles, subject-matter publications, crime statistics, personal interviews with experts, and meta-analyses of previous research on related topics. The research has demonstrated a very strong correlation between exposure to SEIM and hyper-masculine attitudes and behaviors of gender-inequality toward women, beginning at one end of the spectrum with verbal micro-aggressions or misogynistic cultural biases and ending at the other end with sexual assault or sexual abuse, depending on external factors of the user including environmental, social, family of origin, and psychological. The conclusion is that any exposure to SEIM relates to negative attitudes and behaviors toward women, but that specific types of individuals are more effected by such exposure. All exposure to these materials should be limited to avoid continued gender-inequality in our society

Actividade profissional da mãe e escolaridade das crianças

Inexistenteinfo:eu-repo/semantics/publishedVersio

Quantitative trait loci linked to PRNP gene controlling health and production traits in INRA 401 sheep

In this study, the potential association of PrP genotypes with health and productive traits was investigated. Data were recorded on animals of the INRA 401 breed from the Bourges-La Sapinière INRA experimental farm. The population consisted of 30 rams and 852 ewes, which produced 1310 lambs. The animals were categorized into three PrP genotype classes: ARR homozygous, ARR heterozygous, and animals without any ARR allele. Two analyses differing in the approach considered were carried out. Firstly, the potential association of the PrP genotype with disease (Salmonella resistance) and production (wool and carcass) traits was studied. The data used included 1042, 1043 and 1013 genotyped animals for the Salmonella resistance, wool and carcass traits, respectively. The different traits were analyzed using an animal model, where the PrP genotype effect was included as a fixed effect. Association analyses do not indicate any evidence of an effect of PrP genotypes on traits studied in this breed. Secondly, a quantitative trait loci (QTL) detection approach using the PRNP gene as a marker was applied on ovine chromosome 13. Interval mapping was used. Evidence for one QTL affecting mean fiber diameter was found at 25 cM from the PRNP gene. However, a linkage between PRNP and this QTL does not imply unfavorable linkage disequilibrium for PRNP selection purposes

Urocortin 2 Gene Transfer Improves Glycemic Control and Reduces Retinopathy and Mortality in Murine Insulin Deficiency.

Type 1 diabetes affects 20 million patients worldwide. Insulin is the primary and commonly the sole therapy for type 1 diabetes. However, only a minority of patients attain the targeted glucose control and reduced adverse events. We tested urocortin 2 gene transfer as single-agent therapy for insulin deficiency using two mouse models. Urocortin 2 gene transfer reduced blood glucose for months after a single intravenous injection, through increased skeletal muscle insulin sensitivity, increased insulin release in response to glucose stimulation, and increased plasma insulin levels before and during euglycemic clamp. The combined increases in both insulin availability and sensitivity resulted in improved glycemic indices-events that were not anticipated in these insulin-deficient models. In addition, urocortin 2 gene transfer reduced ocular manifestations of long-standing insulin deficiency such as vascular leak and improved retinal function. Finally, mortality was reduced by urocortin 2 gene transfer. The mechanisms for these beneficial effects included increased activities of AMP-activated protein kinase and Akt (protein kinase B) in skeletal muscle, increased skeletal muscle glucose uptake, and increased insulin release. These data suggest that urocortin 2 gene transfer may be a viable therapy for new onset type 1 diabetes and might reduce insulin needs in later stage disease

Antagonistic control of muscle cell size by AMPK and mTORC1.

7 pages (2640-2646)International audienceNutrition and physical activity have profound effects on skeletal muscle metabolism and growth. Regulation of muscle mass depends on a thin balance between growth-promoting and growth-suppressing factors. Over the past decade, the mammalian target of rapamycin (mTOR) kinase has emerged as an essential factor for muscle growth by mediating the anabolic response to nutrients, insulin, insulin-like growth factors and resistance exercise. As opposed to the mTOR signaling pathway, the AMP-activated protein kinase (AMPK) is switched on during starvation and endurance exercise to upregulate energy-conserving processes. Recent evidence indicates that mTORC1 (mTOR Complex 1) and AMPK represent two antagonistic forces governing muscle adaption to nutrition, starvation and growth stimulation. Animal knockout models with impaired mTORC1 signaling showed decreased muscle mass correlated with increased AMPK activation. Interestingly, AMPK inhibition in p70S6K-deficient muscle cells restores cell growth and sensitivity to nutrients. Conversely, muscle cells lacking AMPK have increased mTORC1 activation with increased cell size and protein synthesis rate. We also demonstrated that the hypertrophic action of MyrAkt is enhanced in AMPK-deficient muscle, indicating that AMPK acts as a negative feedback control to restrain muscle hypertrophy. Our recent results extend this notion by showing that AMPKα1, but not AMPKα2, regulates muscle cell size through the control of mTORC1 signaling. These results reveal the diverse functions of the two catalytic isoforms of AMPK, with AMPKα1 playing a predominant role in the control of muscle cell size and AMPKα2 mediating muscle metabolic adaptation. Thus, the crosstalk between AMPK and mTORC1 signaling is a highly regulated way to control changes in muscle growth and metabolic rate imposed by external cues

Genetic parameters for�resistance to the Salmonella abortusovis vaccinal strain Rv6 in sheep

An experimental population (1216 lambs from 30 sires) of the Inra401 sheep was created in an Inra flock to allow QTL detection for susceptibility to Salmonella infection, wool and carcass traits. The Inra401 is a sheep composite line developed from two breeds: Berrichon du Cher and Romanov. At 113 days of age on average, the lambs were inoculated intravenously with 10(8 )Salmonella abortusovis Rv6 (vaccinal strain). They were slaughtered 10 days after the inoculation. Several traits were measured at inoculation and/or slaughtering to estimate the genetic resistance of the lambs to Salmonella infection: specific IgM and IgG1 antibody titres, body weight loss, spleen and pre-scapular node weights and counts of viable Salmonella persisting in these organs. This paper presents a quantitative analysis of the genetic variability of the traits related to salmonellosis susceptibility. The heritabilities of the traits varied between 0.10 and 0.64 (significantly different from zero). Thus, in sheep as well as in other species, the determinism of resistance to Salmonella infection is under genetic control. Moreover, the correlations between the traits are in agreement with the known immune mechanisms. The genetic variability observed should help QTL detection