26 research outputs found
Features of psychoemotional disorders in patients with multiple sclerosis in different clinical and demographic groups
Purpose: to conduct an analysis of psychoemotional disorders in patients with multiple sclerosis, who are not receiving any treatment for these disorders. Material and Methods. A cohort of patients with a reliable diagnosis of multiple sclerosis, according to the criteria of Π‘ Poseur, consisting of 163 people, was selected for the research. A four-dimensional symptomatic questionnaire was used to assess distress, depression, anxiety and somatization (4DSQ) and a self-questionnaire for evaluating the symptoms of fibromyalgia with quantitative measures (WPI, SS, FS). Re-sults. Differences in the average values of the level of distress, depression, anxiety and somatization in patients with multiple sclerosis of different sex, age, with different type of course and duration of the disease are shown. Conclusion. The neuropsychological status of patients depends on the type of course of the disease, the level of distress β from age and sex, the level of somatization βfrom the age of this category of patients. In the complex treatment of this category of patients it is necessary to use symptomatic treatment in addition to pathogenetic therapy, which has not only neurotrophic and vasoactive effects, but also affects the psychoemotional background of patients.</p
Public knowledge of risk factors, signs and treatment of stroke: Analysis of the survey results in 2014 and 2017
Aim. This study was conducted to establish levels of knowledge in the general population, and also to determine the impact of educational sessions on stroke knowledge. Material and Methods. Two groups (2014 and 2017 years) completed a stroke knowledge questionnaire (435 respondents). Results. Overall, most of respondents could list 2 or more risk factors, but only 50% in 2014 could list 3 warning signs. More than 80% would call emergency number in response to stroke, but only 25% had heard of thrombolytic therapy. Overall stroke knowledge scores decreased in 2017 despite the public awareness in the media. Conclusion. Currently the knowledge of stroke risk factors, warning signs, and treatment is poor in Saratov. Our study demonstrates that more educational campaigns should be conducted for improve knowledge of stroke symptoms, and therapy.</p
ΠΠΠΠ£ΠΠΠΠΠΠΠ’ΠΠ§ΠΠ‘ΠΠΠ ΠΠ‘ΠΠΠΠ’Π« Π ΠΠΠΠΠΠ Π ΠΠΠΠΠ’ΠΠΠΠΠΠΠ ΠΠ Π’Π ΠΠ’Π
The study is aimed to investigate the distribution of alleles of HLA-DRB1 gene in patients with early rheumatoid arthritis and healthy individuals in Russian population, and evaluate their significance as molecular genetic markers of rheumatoid arthritis predisposition and protection. The association between alleles of HLA-DRB1 genes, antibodies to cyclic citrullinated peptides and IgM rheumatoid factor was also studied. Low and high resolution HLA-DRB1 genotyping were compared. In the cohort of patients with early rheumatoid arthritis, the alleles of HLA-DRB1 gene were found to be markers of rheumatoid arthritis protection/risk, especially in the homozygous state. They determined production of antibodies to cyclic citrullinated peptides but were not associated with rheumatoid factor IgM levels. These findings support different autoimmune mechanisms of rheumatoid arthritis pathogenesis.Β ΠΠ·ΡΡΠ΅Π½ΠΎ ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ Π°Π»Π»Π΅Π»Π΅ΠΉ Π³Π΅Π½Π° HLA-DRB1 Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΠ°Π½Π½ΠΈΠΌ ΡΠ΅Π²ΠΌΠ°ΡΠΎΠΈΠ΄Π½ΡΠΌ Π°ΡΡΡΠΈΡΠΎΠΌ ΠΈ Π·Π΄ΠΎΡΠΎΠ²ΡΡ
Π»ΠΈΡ ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ ΡΠΎΡΡΠΈΠΉΡΠΊΠΎΠΉ ΠΏΠΎΠΏΡΠ»ΡΡΠΈΠΈ ΠΈ ΠΎΡΠ΅Π½Π΅Π½Π° ΠΈΡ
Π·Π½Π°ΡΠΈΠΌΠΎΡΡΡ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΠΌΠΎΠ»Π΅ΠΊΡΠ»ΡΡΠ½ΠΎ-Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΌΠ°ΡΠΊΠ΅ΡΠΎΠ² ΠΏΡΠ΅Π΄ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΠΈ ΠΏΡΠΎΡΠ΅ΠΊΡΠΈΠΈ ΡΠ΅Π²ΠΌΠ°ΡΠΎΠΈΠ΄Π½ΠΎΠ³ΠΎ Π°ΡΡΡΠΈΡΠ°. ΠΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π° ΡΠΈΠ»Π° Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΠ²Π½ΠΎΠΉ ΡΠ²ΡΠ·ΠΈ Π°Π»Π»Π΅Π»Π΅ΠΉ Π³Π΅Π½Π° HLA-DRB1 Ρ ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ΅ΠΉ Π°Π½ΡΠΈΡΠ΅Π» ΠΊ ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠΈΡΡΡΠ»Π»ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌ ΠΏΠ΅ΠΏΡΠΈΠ΄Π°ΠΌ ΠΈ ΡΠ΅Π²ΠΌΠ°ΡΠΎΠΈΠ΄Π½ΠΎΠΌΡ ΡΠ°ΠΊΡΠΎΡΡ ΠΊΠ»Π°ΡΡΠ° Π. Π ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΎ ΡΡΠ°Π²Π½Π΅Π½ΠΈΠ΅ ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² Π²ΡΡΠΎΠΊΠΎ- ΠΈ Π½ΠΈΠ·ΠΊΠΎΡΠ°Π·ΡΠ΅ΡΠ°ΡΡΠ΅Π³ΠΎ Π³Π΅Π½ΠΎΡΠΈΠΏΠΈΡΠΎΠ²Π°Π½ΠΈΡ Π°Π»Π»Π΅Π»Π΅ΠΉ HLA-DRB1. Π£ Π±ΠΎΠ»ΡΠ½ΡΡ
ΡΠ°Π½Π½ΠΈΠΌ ΡΠ΅Π²ΠΌΠ°ΡΠΎΠΈΠ΄Π½ΡΠΌ Π°ΡΡΡΠΈΡΠΎΠΌ ΠΎΠ±Π½Π°ΡΡΠΆΠ΅Π½Ρ Π°Π»Π»Π΅Π»ΠΈ Π³Π΅Π½Π° HLA-DRB1, ΡΠ²Π»ΡΡΡΠΈΠ΅ΡΡ ΠΌΠ°ΡΠΊΠ΅ΡΠ°ΠΌΠΈ ΡΠΈΡΠΊΠ° ΠΈ ΠΏΡΠΎΡΠ΅ΠΊΡΠΈΠΈ ΡΠ΅Π²ΠΌΠ°ΡΠΎΠΈΠ΄Π½ΠΎΠ³ΠΎ Π°ΡΡΡΠΈΡΠ°, Π΄Π΅ΡΠ΅ΡΠΌΠΈΠ½ΠΈΡΡΡΡΠΈΠ΅ ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΡ Π°Π½ΡΠΈΡΠ΅Π» ΠΊ ΡΠΈΠΊΠ»ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠΈΡΡΡΠ»Π»ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΠΌ ΠΏΠ΅ΠΏΡΠΈΠ΄Π°ΠΌ, Π½ΠΎ Π½Π΅ Π°ΡΡΠΎΡΠΈΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ Ρ Π°Π½ΡΠΈΡΠ΅Π»Π°ΠΌΠΈ ΠΊΠ»Π°ΡΡΠ° M ΠΊ ΡΠ΅Π²ΠΌΠ°ΡΠΎΠΈΠ΄Π½ΠΎΠΌΡ ΡΠ°ΠΊΡΠΎΡΡ. ΠΠΎΠ»ΡΡΠ΅Π½Π½ΡΠ΅ Π΄Π°Π½Π½ΡΠ΅ ΠΌΠΎΠ³ΡΡ ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΠΎΠ²Π°ΡΡ ΠΎ ΡΠ°Π·Π»ΠΈΡΠ½ΡΡ
Π°ΡΡΠΎΠΈΠΌΠΌΡΠ½Π½ΡΡ
ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌΠ°Ρ
ΠΏΠ°ΡΠΎΠ³Π΅Π½Π΅Π·Π° ΡΠ΅Π²ΠΌΠ°ΡΠΎΠΈΠ΄Π½ΠΎΠ³ΠΎ Π°ΡΡΡΠΈΡΠ°.Β
Discriminação entre estÑgios nutricionais na cultura do trigo com técnicas de visão artificial e medidor portÑtil de clorofila
Assessment level of anxiety and depression in patients with multiple sclerosis
<p>In patients with multiple sclerosis observed polymorphism of the emergency psychiatric disorders with a wide range of psychopathological phenomena β from neurotic and personality disorders to psychotic states and epileptiform syndrome. However, the problems of mental health problems in people with MS for a long time little attention was paid. The aim of our study was to analyze the level of anxiety and depression severity in patients with multiple sclerosis. According to this objective have been identifed objectives of the study: to determine the level of depression and anxiety in MS patients according to sex, age, course, duration of disease. For our work was selected group of patients with documented diagnosis of multiple sclerosis, Charles Poser criteria, consisting of 79 persons, with a disease duration of more than 2 years. We used a specially designed questionnaire, which included a table to assess complaints, anamnesis, the neurological status of the patient, and standard questionnaires (test anxiety, Taylor Depression Scale Research psychoneurology them. Spondylitis, the index of overall psychological well-being). The study found that mood disorders such as anxiety, depression, often occurs in patients with multiple sclerosis. However, they are expressed in groups of patients receiving and not receiving DMD, in many ways. Thus, it should be recommended&nbsp; Vat practical neurologists in the treatment of multiple sclerosis patients to pay attention to whether or not they have a certain range of mental disorders, and above all, anxious-depressive syndrome, which is in need of medical and non-pharmacological correction.</p>
Headache features in persons with anxiety disorders
The aim of the article is to estimate the impact of anxiety on personality characteristics of headache in young adults studying full-time. Material and Methods. We observed 92 people aged from 15 to 25 years old, socially adapted, students in schools, colleges and universities on a full-time offices. Results. The perception of headache strongly depends on the emotional state of the individual, so it is very important to take this into account in the analysis of complaints and anamnesis of patients. Conclusion. Anxiety personality disorders hinder objectifying cephalgia, leading to misdiagnosis and incorrect treatment tactically with the possible development of abuse headaches. Therefore, it is necessary to convey to the patient the importance of reducing the impact of modifiable risk factors to explain the relationship of his condition with these factors and create a positive attitude to treatment
The role of transient ischemic attacks in the occurrence of cognitive impairment
The information about cognitive impairment of patient, suffered from transient ischemic attack (TIA) is summarized on the base of Russian and foreign literature. There were considered primary risk factors and pathogenesis of the occurrence of TIA and cognitive impairment. The algorithm of examination of patients with TIA was presented
Π Π΅Π΄ΠΊΠΈΠΉ ΡΠ»ΡΡΠ°ΠΉ Π΄ΡΠΎΠ΄Π΅Π½ΠΎ-ΠΎΠ±ΠΎΠ΄ΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠ²ΠΈΡΠ° Ρ ΡΠ΅Π±Π΅Π½ΠΊΠ° 3 Π»Π΅Ρ
Intraintestinal fistula is an unnatural communication between the intestinal cavity and other parts of the gut. Duodenocolic fistulas are common in adult patients with duodenal peptic ulcer or colon malignancies. In children, the formation of intraintestinal fistulas is possible as aΒ rare complication of necrotizing enterocolitis of the newborn, after swallowing of several (two and more) magnetic foreign bodies localized in different parts of the digestive tract, as well as aΒ complication of Crohn's disease at an older age. The article presents aΒ clinical case of aΒ duodenocolic fistula in aΒ 3-year-old child. The patient Sh., 3Β years and 2Β months old, was admitted to the Pediatric Department of our clinic with aΒ malabsorption syndrome and complaints of periodic vomiting after meals, weakness, tiredness, unstable light grayish stools, flatulence, periodic abdominal pains, and weight loss. There were clinical signs of stage II hypotrophy, protein and energy insufficiency. Laboratory tests showed low protein, albumin, and cholesterol levels, hypochromic anemia; fecal steatorrhea, creatorrhea, and amilorrhea. The differential diagnosis included intestinal malabsorption syndrome, presumably of aΒ secondary origin, intestinal infection, congenital pancreatic disease, hereditary metabolic disorders, cystic fibrosis, celiac disease, lambliosis, and tumor. Multiple endoscopic and radiological examinations of the gastrointestinal tract were performed, but the intraintestinal fistula was identified only after repeated examinations. The patient's medical history from the first referral to the final diagnosis lasted about 9Β months. The mechanism of the fistula formation in this patient is unclear. The clinical manifestation corresponded to the location of the fistula. In the long-term, the functioning of pathological intraintestinal communication could have aΒ negative impact on the growth and development of the child; mucosal atrophy of the descending part of the intestine would have been possible, with progressive cachexy that could have become fatal.ΠΠ΅ΠΆΠΊΠΈΡΠ΅ΡΠ½ΡΠΉ ΡΠ²ΠΈΡΒ β Π½Π΅Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΡ, ΡΠΎΠ΅Π΄ΠΈΠ½ΡΡΡΠ°Ρ ΠΏΠΎΠ»ΠΎΡΡΡ ΠΊΠΈΡΠΊΠΈ ΡΒ Π΄ΡΡΠ³ΠΈΠΌΠΈ ΠΎΡΠ΄Π΅Π»Π°ΠΌΠΈ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ°. ΠΡΠΎΠ΄Π΅Π½Π°Π»ΡΠ½ΠΎ-ΠΎΠ±ΠΎΠ΄ΠΎΡΠ½ΡΠ΅ ΡΠ²ΠΈΡΠΈ ΠΎΠ±ΡΡΠ½ΠΎ Π²ΡΡΡΠ΅ΡΠ°ΡΡΡΡ ΡΒ Π²Π·ΡΠΎΡΠ»ΡΡ
ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠ² ΡΒ ΡΠ·Π²Π΅Π½Π½ΠΎΠΉ Π±ΠΎΠ»Π΅Π·Π½ΡΡ Π΄Π²Π΅Π½Π°Π΄ΡΠ°ΡΠΈΠΏΠ΅ΡΡΡΠ½ΠΎΠΉ ΠΊΠΈΡΠΊΠΈ Π»ΠΈΠ±ΠΎ ΠΏΡΠΈ Π·Π»ΠΎΠΊΠ°ΡΠ΅ΡΡΠ²Π΅Π½Π½ΡΡ
ΠΎΠΏΡΡ
ΠΎΠ»ΡΡ
ΡΠΎΠ»ΡΡΠΎΠΉ ΠΊΠΈΡΠΊΠΈ. Π£Β Π΄Π΅ΡΠ΅ΠΉ ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΌΠ΅ΠΆΠΊΠΈΡΠ΅ΡΠ½ΡΡ
ΡΠ²ΠΈΡΠ΅ΠΉ Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎ ΠΊΠ°ΠΊ ΡΠ΅Π΄ΠΊΠΎΠ΅ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠ΅ ΠΏΠ΅ΡΠ΅Π½Π΅ΡΠ΅Π½Π½ΠΎΠ³ΠΎ Π½Π΅ΠΊΡΠΎΡΠΈΠ·ΠΈΡΡΡΡΠ΅Π³ΠΎ ΡΠ½ΡΠ΅ΡΠΎΠΊΠΎΠ»ΠΈΡΠ° Π²Β ΠΏΠ΅ΡΠΈΠΎΠ΄Π΅ Π½ΠΎΠ²ΠΎΡΠΎΠΆΠ΄Π΅Π½Π½ΠΎΡΡΠΈ, ΠΏΡΠΈ ΠΏΡΠΎΠ³Π»Π°ΡΡΠ²Π°Π½ΠΈΠΈ Π½Π΅ΡΠΊΠΎΠ»ΡΠΊΠΈΡ
ΠΌΠ°Π³Π½ΠΈΡΠ½ΡΡ
ΠΈΠ½ΠΎΡΠΎΠ΄Π½ΡΡ
ΡΠ΅Π» (Π΄Π²Π° ΠΈΒ Π±ΠΎΠ»Π΅Π΅), ΠΊΠΎΠ³Π΄Π° ΠΎΠ½ΠΈ ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»ΡΡΡΡΡ Π²Β ΡΠ°Π·Π½ΡΡ
ΠΎΡΠ΄Π΅Π»Π°Ρ
ΠΏΠΈΡΠ΅Π²Π°ΡΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ°, Π°Β ΡΠ°ΠΊΠΆΠ΅ ΠΊΠ°ΠΊ ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½ΠΈΠ΅ Π±ΠΎΠ»Π΅Π·Π½ΠΈ ΠΡΠΎΠ½Π° Π²Β Π±ΠΎΠ»Π΅Π΅ ΡΡΠ°ΡΡΠ΅ΠΌ Π²ΠΎΠ·ΡΠ°ΡΡΠ΅. ΠΒ ΡΡΠ°ΡΡΠ΅ ΠΎΠΏΠΈΡΠ°Π½ΠΎ ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½ΠΎΠ΅ Π½Π°Π±Π»ΡΠ΄Π΅Π½ΠΈΠ΅ Π΄ΡΠΎΠ΄Π΅Π½ΠΎ-ΠΎΠ±ΠΎΠ΄ΠΎΡΠ½ΠΎΠ³ΠΎ ΡΠ²ΠΈΡΠ° ΡΒ ΡΠ΅Π±Π΅Π½ΠΊΠ° ΡΡΠ΅Ρ
Π»Π΅Ρ. ΠΠ°ΡΠΈΠ΅Π½Ρ Π¨., 3Β Π³ΠΎΠ΄Π° 2Β ΠΌΠ΅ΡΡΡΠ°, ΠΏΠΎΡΡΡΠΏΠΈΠ» Π²Β ΠΏΠ΅Π΄ΠΈΠ°ΡΡΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΎΡΠ΄Π΅Π»Π΅Π½ΠΈΠ΅ ΠΊΠ»ΠΈΠ½ΠΈΠΊΠΈ ΡΒ ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ Π½Π°ΡΡΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ°ΡΡΠ²Π°Π½ΠΈΡ ΠΈΒ ΠΆΠ°Π»ΠΎΠ±Π°ΠΌΠΈ Π½Π° ΠΏΠ΅ΡΠΈΠΎΠ΄ΠΈΡΠ΅ΡΠΊΡΡ ΡΠ²ΠΎΡΡ ΠΏΠΎΡΠ»Π΅ Π΅Π΄Ρ, ΡΠ»Π°Π±ΠΎΡΡΡ, Π²ΡΠ»ΠΎΡΡΡ, Π½Π΅ΡΡΡΠΎΠΉΡΠΈΠ²ΡΠΉ ΡΡΡΠ» ΡΠ²Π΅ΡΠ»ΠΎ-ΡΠ΅ΡΠΎΠ³ΠΎ ΡΠ²Π΅ΡΠ°, ΠΌΠ΅ΡΠ΅ΠΎΡΠΈΠ·ΠΌ, ΠΏΠ΅ΡΠΈΠΎΠ΄ΠΈΡΠ΅ΡΠΊΡΡ Π±ΠΎΠ»Ρ Π²Β ΠΆΠΈΠ²ΠΎΡΠ΅, ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΠ΅ Π²Π΅ΡΠ°. ΠΡΠΌΠ΅ΡΠ°Π»ΠΈΡΡ ΠΏΡΠΈΠ·Π½Π°ΠΊΠΈ Π³ΠΈΠΏΠΎΡΡΠΎΡΠΈΠΈ II ΡΡΠ΅ΠΏΠ΅Π½ΠΈ, Π±Π΅Π»ΠΊΠΎΠ²ΠΎ-ΡΠ½Π΅ΡΠ³Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π½Π΅Π΄ΠΎΡΡΠ°ΡΠΎΡΠ½ΠΎΡΡΠΈ. ΠΠΎ Π΄Π°Π½Π½ΡΠΌ Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΡΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΠΊΡΠΎΠ²ΠΈ Π²ΡΡΠ²Π»Π΅Π½Ρ Π³ΠΈΠΏΠΎΠΏΡΠΎΡΠ΅ΠΈΠ½Π΅ΠΌΠΈΡ, Π³ΠΈΠΏΠΎΠ°Π»ΡΠ±ΡΠΌΠΈΠ½Π΅ΠΌΠΈΡ, Π³ΠΈΠΏΠΎΡ
ΠΎΠ»Π΅ΡΡΠ΅ΡΠΈΠ½Π΅ΠΌΠΈΡ, Π³ΠΈΠΏΠΎΡ
ΡΠΎΠΌΠ½Π°Ρ Π°Π½Π΅ΠΌΠΈΡ, Π²Β ΠΊΠ°Π»Π΅Β β ΡΡΠ΅Π°ΡΠΎΡΠ΅Ρ, ΠΊΡΠ΅Π°ΡΠΎΡΠ΅Ρ, Π°ΠΌΠΈΠ»ΠΎΡΠ΅Ρ. ΠΡΠΎΠ²ΠΎΠ΄ΠΈΠ»Π°ΡΡ Π²Π΅ΡΠΈΡΠΈΠΊΠ°ΡΠΈΡ Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° ΠΌΠ΅ΠΆΠ΄Ρ ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ Π½Π°ΡΡΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ Π²ΡΠ°ΡΡΠ²Π°Π½ΠΈΡ, ΠΏΡΠ΅Π΄ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎ Π²ΡΠΎΡΠΈΡΠ½ΠΎΠ³ΠΎ Π³Π΅Π½Π΅Π·Π°, ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ, Π²ΡΠΎΠΆΠ΄Π΅Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠ΅ΠΉ ΠΏΠΎΠ΄ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ, Π½Π°ΡΠ»Π΅Π΄ΡΡΠ²Π΅Π½Π½ΡΠΌ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΠΎΠ±ΠΌΠ΅Π½Π° Π²Π΅ΡΠ΅ΡΡΠ², ΠΌΡΠΊΠΎΠ²ΠΈΡΡΠΈΠ΄ΠΎΠ·ΠΎΠΌ, ΡΠ΅Π»ΠΈΠ°ΠΊΠΈΠ΅ΠΉ, Π»ΡΠΌΠ±Π»ΠΈΠΎΠ·ΠΎΠΌ, ΠΎΠΏΡΡ
ΠΎΠ»Π΅Π²ΡΠΌ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠΌ. ΠΠ΅ΠΎΠ΄Π½ΠΎΠΊΡΠ°ΡΠ½ΠΎ ΠΎΡΡΡΠ΅ΡΡΠ²Π»ΡΠ»ΠΈΡΡ ΡΠ½Π΄ΠΎΡΠΊΠΎΠΏΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈΒ ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ°, ΠΎΠ΄Π½Π°ΠΊΠΎ Π²ΡΡΠ²ΠΈΡΡ ΠΌΠ΅ΠΆΠΊΠΈΡΠ΅ΡΠ½ΡΠΉ ΡΠ²ΠΈΡ ΡΠ΄Π°Π»ΠΎΡΡ Π»ΠΈΡΡ ΠΏΡΠΈ ΠΏΠΎΠ²ΡΠΎΡΠ½ΠΎΠΌ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ. ΠΠ½Π°ΠΌΠ½Π΅Π· Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΎΡ ΠΌΠΎΠΌΠ΅Π½ΡΠ° ΠΏΠ΅ΡΠ²ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΡ Π·Π° ΠΌΠ΅Π΄ΠΈΡΠΈΠ½ΡΠΊΠΎΠΉ ΠΏΠΎΠΌΠΎΡΡΡ Π΄ΠΎ ΠΏΠΎΡΡΠ°Π½ΠΎΠ²ΠΊΠΈ ΠΎΠΊΠΎΠ½ΡΠ°ΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ Π΄ΠΈΠ°Π³Π½ΠΎΠ·Π° ΡΠΎΡΡΠ°Π²ΠΈΠ» ΠΎΠΊΠΎΠ»ΠΎ 9Β ΠΌΠ΅ΡΡΡΠ΅Π². ΠΠ΅Π½Π΅Π· ΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ²ΠΈΡΠ° ΡΒ Π΄Π°Π½Π½ΠΎΠ³ΠΎ Π±ΠΎΠ»ΡΠ½ΠΎΠ³ΠΎ Π½Π΅ ΡΡΠ΅Π½. ΠΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΠΉ ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Ρ ΡΡΠΎΠ²Π½Π΅ΠΌ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°ΡΠΈΠΈ ΡΠ²ΠΈΡΠ΅Π²ΠΎΠ³ΠΎ Ρ
ΠΎΠ΄Π°. ΠΠ»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ΅ ΡΡΠ½ΠΊΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΌΠ΅ΠΆΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΠΎΠΎΠ±ΡΠ΅Π½ΠΈΡ ΠΌΠΎΠ³Π»ΠΎ Π±Ρ ΠΎΠΊΠ°Π·Π°ΡΡ Π½Π΅Π³Π°ΡΠΈΠ²Π½ΠΎΠ΅ Π²Π»ΠΈΡΠ½ΠΈΠ΅ Π½Π° ΡΠΎΡΡ ΠΈΒ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ ΡΠ΅Π±Π΅Π½ΠΊΠ° Π²Β Π±ΡΠ΄ΡΡΠ΅ΠΌ: Π²ΠΎΠ·ΠΌΠΎΠΆΠ½ΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ Π°ΡΡΠΎΡΠΈΠΈ ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΎΡΠ²ΠΎΠ΄ΡΡΠ΅Π³ΠΎ ΠΎΡΠ΄Π΅Π»Π° ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ°, ΠΏΡΠΎΠ³ΡΠ΅ΡΡΠΈΡΡΡΡΠ΅Π΅ ΠΈΡΡΠΎΡΠ΅Π½ΠΈΠ΅ ΠΌΠΎΠ³Π»ΠΎ Π±Ρ ΠΏΡΠΈΠ²Π΅ΡΡΠΈ ΠΊΒ ΡΠΌΠ΅ΡΡΠΈ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°
Π‘ΡΡΡΠΊΡΡΡΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡΠΊΠΈ ΡΠΎΠ½ΠΊΠΎΠ³ΠΎ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ° Ρ ΡΠΎΠ±Π°ΠΊ ΠΏΡΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Cystoisospora sp. ΠΈ Giardia sp
The protozoa are often the cause of development in dogs of the pathologies of the gastrointestinal tract. At the same time in the early stages there may be no clinical signs of the disease. The aim of our work was to study the structural changes in the mucous membrane of the small intestine in dogs with infection Cystoisospora sp. and Giardia sp. After studying the obtained biopsy specimens in dogs with Cystoisospora sp. duodenitis was established with moderate changes in accordance with the recommendations of the WSAVA Gastrointestinal Standardization Group. The villi of the duodenal mucosa are shortened, unsharply expanded, the epithelial lining is represented by one layer of cells with signs of degenerative changes, the lamina propria is swollen, with moderate infiltration by inflammatory cells - single lymphocytes, single plasma cells, neutrophils, single eosinophils. Infection with Giardia sp. causes disorders of the gastrointestinal tract with signs of moderate and severe inflammatory process. Histoarchitecture of the mucous and muscular membranes of the intestinal tube is partially broken, the epithelial lining is represented by one layer with significant signs of degenerative changes, its own plate is swollen, with marked infiltration by inflammatory cells - lymphocytes, plasma cells, neutrophils, eosinophils. Outside the muscle plate infiltration is practically not distributed. We did not get a direct connection between the severity of the small intestinal lesion during infection with Giardia sp. and clinical manifestations, especially with the severity and frequency of diarrhea.ΠΡΠΎΡΡΠ΅ΠΉΡΠΈΠ΅ Π½Π΅ΡΠ΅Π΄ΠΊΠΎ ΡΡΠ°Π½ΠΎΠ²ΡΡΡΡ ΠΏΡΠΈΡΠΈΠ½ΠΎΠΉ ΡΠ°Π·Π²ΠΈΡΠΈΡ Ρ ΡΠΎΠ±Π°ΠΊ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΉ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ°. ΠΡΠΈ ΡΡΠΎΠΌ Π½Π° ΡΠ°Π½Π½ΠΈΡ
ΡΡΠ°Π΄ΠΈΡΡ
ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΈΠ·Π½Π°ΠΊΠΎΠ² Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡ ΠΌΠΎΠΆΠ΅Ρ Π½Π΅ Π±ΡΡΡ. Π¦Π΅Π»ΡΡ Π½Π°ΡΠ΅ΠΉ ΡΠ°Π±ΠΎΡΡ ΡΡΠ°Π»ΠΎ ΠΈΠ·ΡΡΠΈΡΡ ΡΡΡΡΠΊΡΡΡΠ½ΡΠ΅ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡΠΊΠΈ ΡΠΎΠ½ΠΊΠΎΠ³ΠΎ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ° Ρ ΡΠΎΠ±Π°ΠΊ ΠΏΡΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ Cystoisospora spM Giardia sp. ΠΡΠΎΠ²Π΅Π΄Ρ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠ΅ ΠΏΠΎΠ»ΡΡΠ΅Π½Π½ΡΡ
Π±ΠΈΠΎΠΏΡΠΈΠΉΠ½ΡΡ
ΠΎΠ±ΡΠ°Π·ΡΠΎΠ² Ρ ΡΠΎΠ±Π°ΠΊ Ρ Cystoisospora sp. Π±ΡΠ» ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½ Π΄ΡΠΎΠ΄Π΅Π½ΠΈΡ Ρ ΡΠΌΠ΅ΡΠ΅Π½Π½ΡΠΌΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌΠΈ Π² ΡΠΎΠΎΡΠ²Π΅ΡΡΡΠ²ΠΈΠΈ Ρ ΡΠ΅ΠΊΠΎΠΌΠ΅Π½Π΄Π°ΡΠΈΡΠΌΠΈ WSAVA Gastrointestinal Standardization Group. ΠΠΎΡΡΠΈΠ½ΠΊΠΈ ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡΠΊΠΈ Π΄Π²Π΅Π½Π°Π΄ΡΠ°ΡΠΈΠΏΠ΅ΡΡΡΠ½ΠΎΠΉ ΠΊΠΈΡΠΊΠΈ ΡΠΊΠΎΡΠΎΡΠ΅Π½Ρ, Π½Π΅ΡΠ΅Π·ΠΊΠΎ ΡΠ°ΡΡΠΈΡΠ΅Π½Ρ, ΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½Π°Ρ Π²ΡΡΡΠΈΠ»ΠΊΠ° ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π° ΠΎΠ΄Π½ΠΈΠΌ ΡΠ»ΠΎΠ΅ΠΌ ΠΊΠ»Π΅ΡΠΎΠΊ Ρ ΠΏΡΠΈΠ·Π½Π°ΠΊΠ°ΠΌΠΈ Π΄Π΅Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠ²Π½ΡΡ
ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ, ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΏΠ»Π°ΡΡΠΈΠ½ΠΊΠ° ΠΎΡΠ΅ΡΠ½Π°, Ρ ΡΠΌΠ΅ΡΠ΅Π½Π½ΠΎΠΉ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠ΅ΠΉ ΠΊΠ»Π΅ΡΠΊΠ°ΠΌΠΈ Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ - Π΅Π΄ΠΈΠ½ΠΈΡΠ½ΡΠΌΠΈ Π»ΠΈΠΌΡΠΎΡΠΈΡΠ°ΠΌΠΈ, Π΅Π΄ΠΈΠ½ΠΈΡΠ½ΡΠΌΠΈ ΠΏΠ»Π°Π·ΠΌΠΎΡΠΈΡΠ°ΠΌΠΈ, Π½Π΅ΠΉΡΡΠΎΡΠΈΠ»Π°ΠΌΠΈ, Π΅Π΄ΠΈΠ½ΠΈΡΠ½ΡΠΌΠΈ ΡΠΎΠ·ΠΈΠ½ΠΎΡΠΈΠ»Π°ΠΌΠΈ. ΠΠ°ΡΠ°Π·ΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΠ΅ Giardia sp. ΡΡΠ°Π½ΠΎΠ²ΠΈΡΡΡ ΠΏΡΠΈΡΠΈΠ½ΠΎΠΉ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ ΡΠ°Π±ΠΎΡΡ ΠΆΠ΅Π»ΡΠ΄ΠΎΡΠ½ΠΎ-ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΠΊΡΠ° Ρ ΠΏΡΠΈΠ·Π½Π°ΠΊΠ°ΠΌΠΈ ΡΠΌΠ΅ΡΠ΅Π½Π½ΠΎΠ³ΠΎ ΠΈ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΠ³ΠΎ Π²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°. ΠΠΈΡΡΠΎΠ°ΡΡ
ΠΈΡΠ΅ΠΊΡΠΎΠ½ΠΈΠΊΠ° ΡΠ»ΠΈΠ·ΠΈΡΡΠΎΠΉ ΠΈ ΠΌΡΡΠ΅ΡΠ½ΠΎΠΉ ΠΎΠ±ΠΎΠ»ΠΎΡΠ΅ΠΊ ΠΊΠΈΡΠ΅ΡΠ½ΠΎΠΉ ΡΡΡΠ±ΠΊΠΈ ΡΠ°ΡΡΠΈΡΠ½ΠΎ Π½Π°ΡΡΡΠ΅Π½Π°, ΡΠΏΠΈΡΠ΅Π»ΠΈΠ°Π»ΡΠ½Π°Ρ Π²ΡΡΡΠΈΠ»ΠΊΠ° ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½Π° ΠΎΠ΄Π½ΠΈΠΌ ΡΠ»ΠΎΠ΅ΠΌ ΡΠΎ Π·Π½Π°ΡΠΈΡΠ΅Π»ΡΠ½ΡΠΌΠΈ ΠΏΡΠΈΠ·Π½Π°ΠΊΠ°ΠΌΠΈ Π΄Π΅Π³Π΅Π½Π΅ΡΠ°ΡΠΈΠ²Π½ΡΡ
ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ, ΡΠΎΠ±ΡΡΠ²Π΅Π½Π½Π°Ρ ΠΏΠ»Π°ΡΡΠΈΠ½ΠΊΠ° ΠΎΡΠ΅ΡΠ½Π°, Ρ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΠΉ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠ΅ΠΉ ΠΊΠ»Π΅ΡΠΊΠ°ΠΌΠΈ Π²ΠΎΡΠΏΠ°Π»Π΅Π½ΠΈΡ - Π»ΠΈΠΌΡΠΎΡΠΈΡΠ°ΠΌΠΈ, ΠΏΠ»Π°Π·ΠΌΠΎΡΠΈΡΠ°ΠΌΠΈ, Π½Π΅ΠΉΡΡΠΎΡΠΈΠ»Π°ΠΌΠΈ, ΡΠΎΠ·ΠΈΠ½ΠΎΡΠΈΠ»Π°ΠΌΠΈ. ΠΠ° ΠΏΡΠ΅Π΄Π΅Π»Ρ ΠΌΡΡΠ΅ΡΠ½ΠΎΠΉ ΠΏΠ»Π°ΡΡΠΈΠ½ΠΊΠΈ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°Ρ ΠΏΡΠ°ΠΊΡΠΈΡΠ΅ΡΠΊΠΈ Π½Π΅ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½ΡΠ΅ΡΡΡ. Π£ ΠΆΠΈΠ²ΠΎΡΠ½ΡΡ
, ΠΈΠ½Π²Π°Π·ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
Giardia sp., ΠΌΡ Π½Π΅ ΠΏΠΎΠ»ΡΡΠΈΠ»ΠΈ ΠΏΡΡΠΌΠΎΠΉ ΡΠ²ΡΠ·ΠΈ ΡΡΠΆΠ΅ΡΡΠΈ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ ΡΠΎΠ½ΠΊΠΎΠ³ΠΎ ΠΊΠΈΡΠ΅ΡΠ½ΠΈΠΊΠ° ΠΏΡΠΈ ΠΏΠ°ΡΠ°Π·ΠΈΡΠΈΡΠΎΠ²Π°Π½ΠΈΠΈ ΠΏΡΠΎΡΡΠ΅ΠΉΡΠΈΡ
ΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΡΠΌΠΈ, ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎ Ρ ΡΡΠΆΠ΅ΡΡΡΡ ΠΈ ΡΠ°ΡΡΠΎΡΠΎΠΉ ΠΏΡΠΎΡΠ΅ΠΊΠ°ΡΡΠ΅ΠΉ Π΄ΠΈΠ°ΡΠ΅ΠΈ
Polyneuropathy: clinical polymorphism and the algorithms of diagnostics
The information about epidemiology and clinical polymorphism of neuropathies is summarized on the base of Russian and foreign literature. The algorithm of clinical observation in patients with polyneuropathy is presented