7 research outputs found
Homozygous staggerer (sg/sg) mice display improved insulin sensitivity and enhanced glucose uptake in skeletal muscle
- Author
- A Mamontova
- AD Baron
- AG Smith
- AG Smith
- AM Jetten
- B Friedrich
- BA Hamilton
- BL Wagner
- C Schmitz-Peiffer
- C Sztalryd
- D An
- DA Gold
- E Raspe
- E Raspe
- F Boukhtouche
- F Lang
- G. E. O. Muscat
- GE Muscat
- GR Peck
- H Cho
- H Duez
- HS Kang
- I Dussault
- J Wang
- JT Brozinick Jr
- LD McBroom
- M Bell
- M Schwab
- M Steinmayr
- M. A. Pearen
- M. J. Watt
- MJ Watt
- N Kumar
- N Vu-Dac
- NE Wolins
- OP McGuinness
- P Delerive
- P Delerive
- P Lau
- P Lau
- P. Lau
- R Bertin
- R. L. Fitzsimmons
- RS Garofalo
- S Andrikopoulos
- S Matthaei
- S Raichur
- S Raichur
- U Matysiak-Scholze
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2011
- Field of study
Homozygous staggerer (sg/sg) mice, which have decreased and dysfunctional Ror alpha (also known as Rora) expression in all tissues, display a lean and dyslipidaemic phenotype. They are also resistant to (high fat) diet-induced obesity. We explored whether retinoic acid receptor-related orphan receptor (ROR) alpha action in skeletal muscle was involved in the regulation of glucose metabolism
Teaching nutritional biochemistry: an experimental approach using yeast
- Author
- Publication venue
- 'American Physiological Society'
- Publication date
- Field of study
Disruption of the nuclear hormone receptor RORα in staggerer mice
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Activation of orphan receptor-mediated transcription by Ca(2+)/calmodulin-dependent protein kinase IV
- Author
- Anderson KA
- Anderson KA
- Anderson KA
- Arany Z
- Aronica M
- Bunone G
- Chang C
- Chatila T
- Chawla S
- Chrivia JC
- Cooney AJ
- Dussault I
- Eckner R
- Forman BM
- Frangakis MV
- Gö
- Giguè
- Giguè
- Gonzalez GA
- Guastavino JM
- Hamilton BA
- Harding HP
- Haribabu B
- Heery DM
- Heyman RA
- Hong H
- Hu E
- Jensen KF
- Lau P
- Makishima M
- Matthews RP
- McBroom LD
- Means AR
- Medvedev A
- Miranti CK
- Nghiem P
- Nolte RT
- Norris JD
- Oñ
- Ohmstede CA
- Parks DJ
- Schrä
- Sidman RL
- Steinmayr M
- Sun P
- Sun Z
- Takimoto GS
- Tokumitsu H
- Torchia J
- Trenkner E
- Weigel NL
- White RR
- Wurtz J-M
- Publication venue
- Oxford University Press
- Publication date
- 15/02/2000
- Field of study
Retinoid-related receptor α (RORα) is an orphan nuclear receptor that constitutively activates transcription from its cognate response element. We show that RORα is Ca(2+)responsive, and a Ca(2+)/calmodulin-independent form of Ca(2+)/calmodulin-dependent protein kinase IV (CaMKIV) potentiates RORα-dependent transcription 20- to 30-fold. Other orphan receptors including RORα2, RORγ and COUP-TFI are also potentiated by CaMKIV. Transcriptional activation by CaMKIV is orphan receptor selective and does not occur with either the thyroid hormone or estrogen receptor. CaMKIV does not phosphorylate RORα or its ligand-binding domain (LBD) in vitro, although the LBD is essential for transactivation. Therefore, the RORα LBD was used in the mammalian two-hybrid assay to identify a single class of small peptide molecules containing LXXLL motifs that interacted with greater affinity in the presence of CaMKIV. This class of peptides antagonized activation of orphan receptor-mediated transcription by CaMKIV. These studies demonstrate a pivotal role for CaMKIV in the regulation of orphan receptor-mediated transcription
Molecular effects on a resilient bacterium surviving in outer space
- Author
- A Krisko
- A Kulp
- A Sancar
- A Venkateswaran
- A Yamagishi
- AJ McBroom
- AR Quinlan
- B Basu
- B Langmead
- BA Fox
- BE Moseley
- C Panitz
- C Panitz
- C Trapnell
- C Zhang
- CS Cockell
- D Ghosal
- D Slade
- DM Sweet
- E Ott
- E Ott
- E Rabbow
- ES Reynolds
- F Mastroleo
- FA de Gontijo
- FI Chou
- G Horneck
- HJ Rhee
- J Cox
- J Li
- J-S Park
- JC Caruana
- JJ Truglio
- JK Fredrickson
- JW Wilson
- K Neuberger
- L Selbmann
- LD Fairbanks
- LG Sancho
- M Nakakoshi
- M Potts
- M Wassmann
- MJ Daly
- MJ Daly
- MM Cox
- MR Patel
- O White
- P Rettberg
- PA Vaishampayan
- R Saffary
- RP Rastogi
- S Leuko
- S Mooney
- S Onofri
- T Stojanovic
- U Pogoda de la Vega
- W Weckwerth
- WL Nicholson
- Y Kawaguchi
- Y Kawaguchi
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Membrane Vesicles in Sea Water: Heterogeneous DNA Content and Implications for Viral Abundance Estimates
- Author
- A Bankevich
- A Frias
- A Patel
- AI Culley
- AJ Manning
- AJ McBroom
- AJ Szekely
- AS Lang
- AV Klieve
- BL Deatherage
- BL Hurwitz
- C Camacho
- C PĂ©rez-Cruz
- C PĂ©rez-Cruz
- C Rumbo
- C Schwechheimer
- C Schwechheimer
- CH Wigington
- CP Brussaard
- CPD Brussaard
- CPD Brussaard
- D Marie
- DW Dorward
- DW Dorward
- EJ Biers
- Everett Rogers
- F Chen
- GF Steward
- H Valadi
- H Wickham
- H-W Ackermann
- IA MacDonald
- IA MacDonald
- J Kowal
- J MartĂnez MartĂnez
- JG Stockner
- JL Höög
- JL Kadurugamuwa
- JL Van Etten
- JM Labonté
- John H Paul
- JR Brum
- JR Brum
- JW Schertzer
- K Holmfeldt
- K Rosario
- K-H Kim
- KE Bonnington
- KP Hennes
- L Brown
- L Moore
- L Turnbull
- Lauren D McDaniel
- LD McDaniel
- LF Jover
- LM Proctor
- M Gaudin
- M Hopkins
- M Krupovic
- M Renelli
- M Toyofuku
- M Yáñez-Mó
- MB Sullivan
- MG Fischer
- MG Weinbauer
- MK Pietilä
- Mya Breitbart
- N Koliha
- N Soler
- N Soler
- NC Kesty
- P Forterre
- P Rath
- PM Berube
- Q Wang
- R Grande
- RJ Parsons
- RT Espejo
- RT Noble
- S Hara
- S Overballe-Petersen
- S Roier
- S Roux
- S Yaron
- Sallie W Chisholm
- SJ Biller
- SJ Biller
- Steven J Biller
- TN Ellis
- Y Jiang
- Y Tomaru
- ZJ Smith
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 08/11/2016
- Field of study
Diverse microbes release membrane-bound extracellular vesicles from their outer surfaces into the surrounding environment. Vesicles are found in numerous habitats including the oceans, where they likely have a variety of functional roles in microbial ecosystems. Extracellular vesicles are known to contain a range of biomolecules including DNA, but the frequency with which DNA is packaged in vesicles is unknown. Here, we examine the quantity and distribution of DNA associated with vesicles released from five different bacteria. The average quantity of double-stranded DNA and size distribution of DNA fragments released within vesicles varies among different taxa. Although some vesicles contain sufficient DNA to be visible following staining with the SYBR fluorescent DNA dyes typically used to enumerate viruses, this represents only a small proportion (\u3c0.01–1%) of vesicles. Thus DNA is packaged heterogeneously within vesicle populations, and it appears that vesicles are likely to be a minor component of SYBR-visible particles in natural sea water compared with viruses. Consistent with this hypothesis, chloroform treatment of coastal and offshore seawater samples reveals that vesicles increase epifluorescence-based particle (viral) counts by less than an order of magnitude and their impact is variable in space and time
Die Pathologie der Avitaminosen und Hypervitaminosen
- Author
- A Albeggiani
- A Aschkenasy
- A Bennandi
- A Brown
- A Brusa
- A Carlsson
- A Carotene
- A Chevallier
- A Chevallier
- A Corcos
- A Cruchaud
- A Dagianti
- A Dury
- A Faller
- A Faller
- A Ferraro
- A Fingerland
- A Forse
- A Froehlich
- A Gellhorn
- A Gellhorn
- A Gerber
- A Gerber
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Giroud
- A Golden
- A Grimm
- A Heise
- A Hirt
- A Hoffer
- A Holst
- A Holst
- A Ingelmansundberg
- A Ingelmansundberg
- A Issidorides
- A JuhaszschÄFfer
- A JuhaszschÄFfer
- A Kirschbaum
- A Kornberg
- A Kornberg
- A Kornberg
- A Kornberg
- A Krupski
- A Krupski
- A Libretti
- A Mariakulandai
- A Matet
- A Mex
- A Minkowski
- A Minkowski
- A Morelli
- A MUsIni
- A Narrozzi
- A Narrozzi
- A Pirie
- A Pirie
- A Pittoni
- A Prader
- A Schleich
- A Sesmarais
- A Steiger
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Studer
- A Szentgyorgy
- A Tannenbaum
- A Tannenbaum
- A Taylor
- A Taylor
- A Terbruggen
- A Volta
- A Werthemann
- A Werthemann
- A Windaus
- A Wolf
- A Wolf
- A. H. Douthwaite
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
- AA Nelson
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- AB Watts
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- AC Wiese
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- AD Laurence
- AD Welch
- AE Axelrod
- AE Axelrod
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- AE Schaefer
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- AJ Maw
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- AK Raychaudhury
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- AT Milhorat
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- AV Muralt
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- B Green
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- B Lindsay
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- D Afonsky
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- D Bianchi
- D Bianchi
- D Dennybrown
- D Gribetz
- D Gribetz
- D Horrigan
- D Koch-Weser
- D Laszlo
- D Leigh
- D Maibauer
- D Mceachern
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- D Perla
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- D. E. ZisiIN
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- S Vgami
- S Vgami
- S Wasserman
- S Weiss
- S Weiss
- S. K. Elster
- S. W. LrPpincott
- SA Barnett
- SA Dangelo
- SA Singal
- SA Singal
- SA Singal
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbach
- SB Wolbacit
- SB Wolbacu
- SB Wolrach
- SC Chang
- SC Smith
- SC Stothers
- SC Stothers
- SC Stothers
- SE Goldzier
- SE Snyderman
- SE Walker
- SG Ross
- SG Smith
- SG Smith
- SJ Hartfall
- SJ Piliero
- SK Elster
- SQ Cohlan
- SQ Cohlan
- SQ Cohlan
- SQ Conman
- SR Ames
- SR Ames
- SR Ames
- SR Ames
- SR Ames
- SS Chernick
- SS Chernick
- SS Spicer
- SS Spicer
- SS Turesky
- SS Turesky
- SS Turesky
- SW Clausen
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SW Lippincott
- SY Pan
- T Barlow
- T Barlow
- T Barlow
- T Gillman
- T Gordonoff
- T Gordonoff
- T Iwabuchi
- T Masella
- T Moore
- T Moore
- T Moore
- T Moore
- T Terroine
- TA Jukes
- TC Jones
- TC Lonie
- TC Wyatt
- TD Luckey
- TD Spies
- TD Spies
- TE Metre
- TF Zucker
- TH Brandt
- TH Jukes
- TH Tomlinson
- TH Tomrinson
- TJ Cunha
- TJ Cunha
- TJ Haley
- TK Oliver
- TL Miller
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TM Ferguson
- TR Riggs
- TS Argyris
- TW Gullickson
- TW Gullicxson
- Untersuchungen über die Wirksamkeit des Vitamins BB (Pyridoxin) bei diphtherischen Lähmungen
- V Claassen
- V Demole
- V Demole
- V Demole
- V Demole
- V Demole
- V Piccioni
- V Ramalingasfami
- V Ramalingaswami
- V Ramalingaswami
- V Ramalingaswami
- V Ramalingaswami
- V Spampinato
- V Spampinato
- V. L. Hart
- VA Drill
- VD Vigneaud
- VE Kinsey
- VN Patfardhan
- W Antopol
- W Antopol
- W Antopol
- W Antopol
- W Antopol
- W Antopol
- W Antopol
- W Antopol
- W Antopol
- W Antopol
- W Bartley
- W Bartley
- W Becker
- W Birkmayer
- W Birkmayer
- W Bolagna
- W Boltz
- W Burkl
- W Burroughs
- W Burroughs
- W Creutzfeld
- W Daubenmerkl
- W Daubenmerkl
- W Dittrich
- W Eger
- W Ehrengut
- W Ehrengut
- W Fey
- W Goettscii
- W Hessler
- W Hohlweg
- W Hohlweg
- W Kircher
- W Kwiatkowski
- W Landauer
- W Landauer
- W Loffler
- W Marusich
- W Mcfarland
- W Montagna
- W Montagna
- W Muller
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Neuweiler
- W Rozynek
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Ruppel
- W Salmon
- W Sebrell
- W Stepp
- W Stepp
- W Stepp
- W Swoboda
- W Tobler
- W Trager
- W Trager
- W. E. Shute
- W. F. Alexander
- W. W. Fox
- WA Grimes
- WA Krehl
- WA Krehl
- WB Atkinson
- WB Atkinson
- WB Bean
- WB Hawkins
- WB Leftwich
- WB Mcallister
- WB Robertson
- WB Robertson
- WB Robertson
- WB Robertson
- WB Robertson
- WC Aalsmeer
- WC Owens
- WC Russell
- WC Thomas
- WD King
- WD Salmon
- WD Salmon
- WD Salmon
- WD Salmon
- WE Germeraad
- WE Germeraad
- WE Loch
- WE Phillips
- WE Shute
- WF Abercrombie
- WF Orr
- WF Perry
- WG Casselman
- WG Casselman
- WG Hoekstra
- WG Hoekstra
- WG Jaffe
- WG Jaffe
- WG Jaffe
- WG Jaffe
- WH Eddy
- WH Fishman
- WH Fishman
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Griffith
- WH Jr
- WH Sebrell
- WH Sebrell
- WH Sebrell
- WH Sebrell
- WJ Darby
- WJ Emerson
- WJ Griffiths
- WJ Mcganity
- WK Hall
- WK Manning
- WL Money
- WL Money
- WL Money
- WL Williams
- WM Booker
- WM Booker
- WO Brown
- WO Motte
- WO Russell
- WO Russell
- WO Russell
- WP Covell
- WP Covell
- WP Lehrer
- WR Ruegamer
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WS Hartroft
- WT Wong
- WV Drigalski
- WW Cravens
- WW Cravens
- WW Cravens
- WW Cravens
- WW Crnvens
- WW Crnvens
- WW Crnvens
- WW Hawkins
- WW Hawkins
- WW Hawkins
- WW Hawkins
- WW Wainwright
- Y Hosoya
- Y Raoul
- YO Chang
- Z Menschik
- Z Menschik
- Z Menschik
- Z Menschir
- ZM Bacq
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1962
- Field of study