Performance Variables and Technical Penalties of the Split Leap

Los autores desean mostrar su agradecimiento a las gimnastas participantes en este estudio por su esfuerzo entusiasta e implicación durante la ejecución de la habilidad de salto analizadaSe analizó la relación entre las penalizaciones técnicas obtenidas en la ejecución de un elemento gimnástico aislado con el nivel competitivo de las gimnastas, sus características antropométricas y las variables temporales y angulares más importantes analizadas en dicha habilidad. Fueron seleccionadas 29 gimnastas (17,1 ± 3,1 años) procedentes de distintos niveles competitivos. Tres entrenadores evaluaron la ejecución mediante una adaptación del Código de Puntuación. Se observaron asociaciones significativas directas e indirectas (p < 0,05): bajo índice de adiposidad (rho = 0,643), tiempo total de batida (rho = 0,619), tiempo total de vuelo (rho = - 0,596), máxima amplitud articular de caderas (rho = - 0,902) y máxima extensión de los tobillos (rho = - 0,738). La valoración de las penalizaciones así como el uso del nivel competitivo y del Salto Zancada como test específico han resultado ser herramientas útiles para la valoración del rendimientoThe aim of this study was to analyze the relationship between the following aspects: the technical penalties obtained in the execution of an isolated gymnastics element, the competitive level of the gymnasts, their anthropometric characteristics, and the most important temporal and angular variables analyzed in this skill. Twenty nine gymnasts (aged 17.1 ± 3.1 years) from different competition levels were selected. Three coaches evaluated the execution through an adaptation of the Code of Points. Significant direct and indirect associations were observed (p < 0.05): low adiposity index (rho = 0.643), take-off total time (rho = 0.619), flight total time (rho = - 0.596), maximum range of motion of the hips (rho = - 0.902), and maximum extension of ankles (rho = - 0.738). The assessment of penalties as well as the use of competitive level and Split Leap as specific tests, have demonstrated to be useful tools for evaluating performanc

Two Fundamental Concepts in Skeletal Parallel Programming

We define the concepts of nesting mode and interaction mode as they arise in the description of skeletal parallel programming systems. We sugegs

RICORS2040 : The need for collaborative research in chronic kidney disease

Chronic kidney disease (CKD) is a silent and poorly known killer. The current concept of CKD is relatively young and uptake by the public, physicians and health authorities is not widespread. Physicians still confuse CKD with chronic kidney insufficiency or failure. For the wider public and health authorities, CKD evokes kidney replacement therapy (KRT). In Spain, the prevalence of KRT is 0.13%. Thus health authorities may consider CKD a non-issue: very few persons eventually need KRT and, for those in whom kidneys fail, the problem is 'solved' by dialysis or kidney transplantation. However, KRT is the tip of the iceberg in the burden of CKD. The main burden of CKD is accelerated ageing and premature death. The cut-off points for kidney function and kidney damage indexes that define CKD also mark an increased risk for all-cause premature death. CKD is the most prevalent risk factor for lethal coronavirus disease 2019 (COVID-19) and the factor that most increases the risk of death in COVID-19, after old age. Men and women undergoing KRT still have an annual mortality that is 10- to 100-fold higher than similar-age peers, and life expectancy is shortened by ~40 years for young persons on dialysis and by 15 years for young persons with a functioning kidney graft. CKD is expected to become the fifth greatest global cause of death by 2040 and the second greatest cause of death in Spain before the end of the century, a time when one in four Spaniards will have CKD. However, by 2022, CKD will become the only top-15 global predicted cause of death that is not supported by a dedicated well-funded Centres for Biomedical Research (CIBER) network structure in Spain. Realizing the underestimation of the CKD burden of disease by health authorities, the Decade of the Kidney initiative for 2020-2030 was launched by the American Association of Kidney Patients and the European Kidney Health Alliance. Leading Spanish kidney researchers grouped in the kidney collaborative research network Red de Investigación Renal have now applied for the Redes de Investigación Cooperativa Orientadas a Resultados en Salud (RICORS) call for collaborative research in Spain with the support of the Spanish Society of Nephrology, Federación Nacional de Asociaciones para la Lucha Contra las Enfermedades del Riñón and ONT: RICORS2040 aims to prevent the dire predictions for the global 2040 burden of CKD from becoming true

Ultrasound diagnosis of Terson syndrome as an indicator of extreme severity in neurocritical care patients

Introduction: Terson syndrome (TS) is defined as any intraocular haemorrhage identified in patients with acute intracranial pathology. TS appears to be associated with clinical severity in patients with subarachnoid haemorrhage (SAH), but the association is yet to be defined in patients with traumatic brain injury (TBI) and intracerebral haemorrhage (ICH). This study aimed to evaluate the diagnostic performance of ocular ultrasound (OU) and its usefulness in clinical practice. Material and methods: We performed an observational, prospective, single-centre study of neurocritical care patients. We analysed cases and controls, defined according to indirect ophthalmoscopy (IO) and OU findings. We determined the diagnostic characteristics of OU. A multivariate analysis was performed to identify clinically relevant associations. Results: The sample included 91 patients diagnosed with ICH (41.76%), SAH (29.67%), and TBI (28.57%). TS was identified by OU in 8 patients (8.79%) and by IO in 24 (24.37%). The adjusted mortality rate in patients with TS showed an odds ratio (OR) of 4.15 (95% confidence interval [CI], 1.52-11.33). All patients with TS detected by OU presented Glasgow Coma Scale scores < 9, with an elevated risk of needing decompressive craniectomy (OR: 9.84; 95% CI, 1.64-59). OU presented an overall sensitivity of 30.43%, specificity of 98.53%, and diagnostic accuracy of 81.32%. For the detection of vitreous haemorrhage, sensitivity and specificity were 87.5% and 98.5%, respectively. Conclusions: OU diagnosis of TS identifies extremely critical patients, who may require the highest level of care; TS is an independent risk factor for in-hospital mortality. Resumen: Introducción: Se denomina Síndrome de Terson (ST) a cualquier tipo de hemorragia intraocular (HIO), identificada en pacientes con patología aguda intracraneal. El ST parece estar relacionado con la gravedad clínica en la hemorragia subaracnoidea (HSA), pero en pacientes con trauma craneoencefálico (TCE) y hemorragia intracerebral (HIC), su asociación está por definir. Diseñamos este estudio para evaluar el rendimiento de la ecografía ocular (EO) y su utilidad en la práctica clínica. Materiales y métodos: Realizamos un estudio observacional prospectivo, unicéntrico en pacientes neurocríticos. Analizamos los casos con respecto a los controles, identificados con oftalmoscopia indirecta (OI), y por EO. Determinamos las características diagnósticas de la EO. Hicimos un análisis multivariante para determinar asociaciones clínicamente relevantes. Resultados: Se incluyeron 91 pacientes con diagnósticos de HIC (41,76%), HSA (29,67%) y TCE (28,57%). El ST fue identificado por EO en ocho pacientes (8,79%) y en 24 pacientes (24,37%) por OI. La mortalidad ajustada para los pacientes con ST tuvo una OR 4,15 con IC 95% (1,52-11,33). Todos los pacientes con ST identificados por EO presentaron una escala de coma de Glasgow <9 y tuvieron un riesgo elevado de precisar craniectomía descompresiva, una OR 9,84 (1,64-59). La EO alcanzó una sensibilidad global de 30,43%, una especificidad del 98,53%, con una precisión diagnóstica de 81,32. Para la detección de la hemorragia vítrea, una sensibilidad y especificidad del 87,5%, y 98,5% respectivamente. Conclusiones: El ST diagnosticado por EO discrimina pacientes neurocríticos de extrema gravedad que pueden requerir el máximo escalón terapéutico y es un factor independiente de mortalidad intrahospitalaria

Supplementary Material for: Prenatal Diagnosis of a Female Fetus with Ring Chromosome 9, 46,XX,r(9)(p24q34), and a de novo Interstitial 9p Deletion

Ring chromosomes are circular structures formed as a result of breaks in the chromosome arms and the fusion of the proximal broken ends with a loss of distal material, or by fusion of dysfunctional telomeres without any loss. The mechanism underlying this process has not yet been sufficiently explained. Commonly, rings occur as acquired genetic abnormalities; however, sometimes they are found as constitutional aberrations with a prevalence of around 1:50,000 live births. Here, we present a new case of r(9) in a female fetus with intrauterine growth retardation and slight craniofacial dysmorphisms. Both parents had a normal phenotype. Amniotic fluid karyotype showed r(9)(p24q34). An array CGH revealed 3 deletion segments: a ring chromosome with a 2.57-Mb deletion at 9pterp24.2 (chr9:163,131-2,729,722), a 2.60-Mb deletion at 9q34.3qter (chr9:138,523,302-141,122,055), and also a 0.15-Mb interstitial deletion at 9p24.1 (chr9:5,090,443-5,235,765). These deletions overlap with proposed regions for the 9p24.3 deletion and Kleefstra syndrome. Segregation analysis revealed a maternal origin of the rearranged chromosome. We conclude that both the ring chromosome and the interstitial deletion occurred de novo<i>. </i>This last deletion has not been reported before. Prenatal array CGH, combined with fine mapping of breakpoints contributes to the assessment of genotype-phenotype correlations

Monitoring, Modelling and Forecasting of the Pollen Season

The section about monitoring covers the development of phenological networks, remote sensing of the season cycle of the vegetation, the emergence of the science of aerobiology and, more specifically, aeropalynology, pollen sampling instruments, pollen counting techniques, applications of aeropalynology in agriculture and the European Pollen Information System. Three data sources are directly related with aeropalynology: phenological observations, pollen counts and remote sensing of the vegetation activity. The main future challenge is the assimilation of these data streams into numerical pollen forecast systems. Over the last decades consistent monitoring efforts of various national networks have created a wealth of pollen concentration time series. These constitute a nearly untouched treasure, which is still to be exploited to investigate questions concerning pollen emission, transport and deposition. New monitoring methods allow measuring the allergen content in pollen. Results from research on the allergen content in pollen are expected to increase the quality of the operational pollen forecasts