Design and Characterization of a Prototype Stripline Beam Position Monitor for the Clic Drive Beam*

The prototype of a stripline Beam Position Monitor (BPM) with its associated readout electronics is under development at CERN, in collaboration with SLAC, LAPP and IFIC. The anticipated position resolution and accuracy are expected to be below 2μm and 20μm respectively for operation of the BPM in the CLIC drive beam (DB) linac. This paper describes the particular CLIC DB conditions with respect to the beam position monitoring, presents the measurement concept, and summarizes electromagnetic simulations and RF measurements performed on the prototype

Near-IR Atlas of S0-Sa galaxies (NIRS0S)

An atlas of Ks-band images of 206 early-type galaxies is presented, including 160 S0-S0/a galaxies, 12 ellipticals, and 33 Sa galaxies. A majority of the Atlas galaxies belong to a magnitude-limited (mB<12.5 mag) sample of 185 NIRS0S (Near-IR S0 galaxy Survey) galaxies. To assure that mis-classified S0s are not omitted, 25 ellipticals from RC3 classified as S0s in the Carnegie Atlas were included in the sample. The images are 2-3 mag deeper than 2MASS images. Both visual and photometric classifications are made. Special attention is paid to the classification of lenses, coded in a systematic manner. A new lens-type, called a 'barlens', is introduced. Also, boxy/peanut/x-shaped structures are identified in many barred galaxies, even-though the galaxies are not seen in edge-on view, indicating that vertical thickening is not enough to explain them. Multiple lenses appear in 25% of the Atlas galaxies, which is a challenge to the hierarchical evolutionary picture of galaxies. Such models need to explain how the lenses were formed and survived in multiple merger events that galaxies may have suffered during their lifetimes. Following the early suggestion by van den Bergh, candidates of S0c galaxies are shown, which galaxies are expected to be former Sc-type spirals stripped out of gas.Comment: 67 pages (include 16 figures and 6 tables). Accepted to MNRAS 2011 June 1

Assessing the effectiveness of the Ramsar Convention in preserving wintering waterbirds in the Mediterranean

lthough biological conservation is based on international agreements, its effectiveness depends on how countries implement such recommendations as effective conservation tools. The Ramsar Convention is the oldest international treaty for wetland and waterbird conservation, establishing the world's largest network of protected areas. However, since it does not constitute any binding measure, its effectiveness in protecting wintering waterbird populations at an international scale has been questioned. Here, we use long-term (1991–2012) count data to assess the effectiveness of the Ramsar Convention in the Mediterranean Basin. We compared abundance and temporal trends of 114 waterbird species between 251 Ramsar wetlands and 3486 non-Ramsar wetlands. We found that the Ramsar network is critical for wintering waterbirds, concentrating nearly half of all waterbirds counted in the Mediterranean Basin in only 7% of monitored wetlands. Waterbird trends followed a northwestsoutheast gradient, with a population decrease in the East. A significant and positive Ramsar effect on population trends was only found for the species of higher conservation concern in the Maghreb, particularly when a management plan was implemented. The Ramsar Convention was previously used on very important wetlands for waterbirds in Southern Europe, but is now an underused conservation tool. Our study suggests weaknesses in the use of Ramsar as an effective conservation tool in most of the Mediterranean Basin. However, the Ramsar Convention effectiveness to enhance waterbird populations in the Maghreb should encourage strengthening the Ramsar Convention. It should be done particularly in countries with limited environmental agreements and by systematic implementation of management plans. Conservation measures International conventions Protected areas Protection status Monitoring WetlandsacceptedVersio

Variability in lutetium-177 SPECT quantification between different state-of-the-art SPECT/CT systems

Background: Quantitative SPECT imaging in targeted radionuclide therapy with lutetium-177 holds great potential for individualized treatment based on dose assessment. The establishment of dose-effect relations requires a standardized method for SPECT quantification. The purpose of this multi-center study is to evaluate quantitative accuracy and inter-system variations of different SPECT/CT systems with corresponding commercially available quantitative reconstruction algorithms. This is an important step towards a vendor-independent standard for quantitative lutetium-177 SPECT. Methods: Four state-of-the-art SPECT/CT systems were included: Discovery™ NM/CT 670Pro (GE Healthcare), Symbia Intevo™, and two Symbia™ T16 (Siemens Healthineers). Quantitative accuracy and inter-system variations were evaluated by repeatedly scanning a cylindrical phantom with 6 spherical inserts (0.5 – 113 ml). A sphere-to-background activity concentration ratio of 10:1 was used. Acquisition settings were standardized: medium energy collimator, body contour trajectory, photon energy window of 208 keV (± 10%), adjacent 20% lower scatter window, 2 × 64 projections, 128 × 128 matrix size, and 40 s projection time. Reconstructions were performed using GE Evolution with Q.Metrix™, Siemens xSPECT Quant™, Siemens Broad Quantification™ or Siemens Flash3D™ algorithms using vendor recommended settings. In addition, projection data were reconstructed using Hermes SUV SPECT™ with standardized reconstruction settings to obtain a vendor-neutral quantitative reconstruction for all systems. Volumes of interest (VOI) for the spheres were obtained by applying a 50% threshold of the sphere maximum voxel value corrected for background activity. For each sphere, the mean and maximum recovery coefficient (RCmean and RCmax) of three repeated measurements was calculated, defined as the imaged activity concentration divided by the actual activity concentration. Inter-system variations were defined as the range of RC over all systems. Re

Electron Cooling Experiments in CSR

The six species heavy ion beam was accumulated with the help of electron cooling in the main ring of Cooler Storage Ring of Heavy Ion Research Facility in Lanzhou(HIRFL-CSR), the ion beam accumulation dependence on the parameters of cooler was investigated experimentally. The 400MeV/u 12C6+ and 200MeV/u 129Xe54+ was stored and cooled in the experimental ring CSRe, the cooling force was measured in different condition.Comment: 5 pages 11 figure

PMm2: large photomultipliers and innovative electronics for the next-generation neutrino experiments

The next generation of proton decay and neutrino experiments, the post-SuperKamiokande detectors as those that will take place in megaton size water tanks, will require very large surfaces of photodetection and a large volume of data. Even with large hemispherical photomultiplier tubes, the expected number of channels should reach hundreds of thousands. A funded R&D program to implement a solution is presented here. The very large surface of photodetection is segmented in macro pixels made of 16 hemispherical (12 inches) photomultiplier tubes connected to an autonomous front-end which works on a triggerless data acquisition mode. The expected data transmission rate is 5 Mb/s per cable, which can be achieved with existing techniques. This architecture allows to reduce considerably the cost and facilitate the industrialization. This document presents the simulations and measurements which define the requirements for the photomultipliers and the electronics. A proto-type of front-end electronics was successfully tested with 16 photomultiplier tubes supplied by a single high voltage, validating the built-in gain adjustment and the calibration principle. The first tests and calculations on the photomultiplier glass led to the study of a new package optimized for a 10 bar pressure in order to sustain the high underwater pressure.Comment: 1 pdf file, 4 pages, 4 figures, NDIP08, submitted to Nucl. Instr. and Meth. Phys. Res.

Impact of uptake time on image quality of [68 Ga]Ga-PSMA-11 PET/CT

Background: With the introduction of prostate specific membrane antigen (PSMA) PET/CT, the detection rate of prostate cancer metastases has improved significantly, both for primary staging and for biochemical recurrence. EANM/SNMMI guidelines recommend a 60 min time interval between [ 68Ga]Ga-PSMA administration and acquisition. Purpose: This study evaluates the possibility of a shorter time interval by investigating the dynamic change in image quality measures. Method: We retrospectively analyzed 10 consecutive prostate cancer patients who underwent a dynamic whole body [ 68Ga]Ga-PSMA-11 PET/CT of 75 min from skull vertex to mid-thigh using Siemens FlowMotion. PET images were acquired directly after injection of 1.5 MBq/kg [ 68Ga]Ga-PSMA-11. Image quality measures included lesion maximum standardized uptake value corrected for lean body mass (SUL max), tumor-to-background ratio (TBR), and contrast-to-noise ratio (CNR). Quantitative analysis of image quality in dynamic PET was performed using PMOD (version 4.2). Regions of interest (ROIs), drawn included different types of prostate lesions (primary tumor, lymph nodes, and bone metastasis), organ tissue (liver, spleen, lacrimal gland, submandibular gland, parotid gland, urinary bladder, kidneys blood pool [ascending aorta], left ventricle), bone tissue (4th lumbar vertebral body [L4]) and muscle tissue (gluteus maximus). To further investigate image quality four 10 min multi-frame reconstructions with clinical parameters were made at different post-injection times (15, 30, 45, and 60 min). A nuclear medicine physician performed a blinded lesion detectability evaluation on these multi-frame reconstructions for different prostate cancer lesions. Results: Six primary prostate tumors in seven patients with prostate in situ, 13 lymph node metastases in six patients and up to 12 bone metastases in three patients were found. The different prostate lesion types (lymph nodes metastases, bone metastases, and primary prostate tumor) all show an increase in average SUL max, TBR, and CNR over time during the scan. The normalized average SUL max, TBR, and CNR of the combined prostate lesions at 15, 30, and 45 min post-injection scans were all significant p < 0.05 lower from the 60 min post-injection [ 68Ga]Ga-PSMA-11 PET/CT (9.5 ± 4.5, 12.7 ± 6.2, and 41.8 ± 24.5, respectively). At patient level, the reader concluded the same regarding the presence/absence of primary prostate cancer recurrence, lymph node metastases, and/or bone metastases on all <60 min post-injection [ 68Ga]Ga-PSMA-11 PET/CT's in comparison to the reference scan (60 min post-injection). At lesion level, all bone metastases seen on the reference scan were also seen on all <60 min post-injection [ 68Ga]Ga-PSMA-11 PET/CT's but there were some lymph nodes (n = 2) metastases missed on the 15, 30, and 45 min post-injection scans. One lymph node metastasis on both the 15 and 30 min post-injection [ 68Ga]Ga-PSMA-11 PET/CT's was missed and one lymph node metastasis was missed, only on the 45 min post-injection [ 68Ga]Ga-PSMA-11 PET/CT. Conclusion: Shorter post-injection times (15, 30, and 45 min) compared to the recommended post-injection time of 60 min are not optimal. However, the impact of a shorter time interval of 45 min instead of 60 min between [ 68Ga]Ga-PSMA-11 administration and the start of PET/CT acquisition on both image quality (SUL max, TBR, and CNR) and lesion detection, while significant, is small

Relating Habitat and Climatic Niches in Birds

Predicting species' responses to the combined effects of habitat and climate changes has become a major challenge in ecology and conservation biology. However, the effects of climatic and habitat gradients on species distributions have generally been considered separately. Here, we explore the relationships between the habitat and thermal dimensions of the ecological niche in European common birds. Using data from the French Breeding Bird Survey, a large-scale bird monitoring program, we correlated the habitat and thermal positions and breadths of 74 bird species, controlling for life history traits and phylogeny. We found that cold climate species tend to have niche positions in closed habitats, as expected by the conjunction of the biogeographic history of birds' habitats, and their current continent-scale gradients. We also report a positive correlation between thermal and habitat niche breadths, a pattern consistent with macroecological predictions concerning the processes shaping species' distributions. Our results suggest that the relationships between the climatic and habitat components of the niche have to be taken into account to understand and predict changes in species' distributions